Human Bone Cell Research Group
Department of Human Anatomy and Cell Biology
New Medical School
Ashton Street
Liverpool
L69 3GE
UK
Tel +44 (0)151 794 5505
Fax +44 (0)151 794 5517
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The Human Bone Cell Research group, based in the Department of Human
Anatomy and Cell Biology, is one of the largest research groups in the
University of Liverpool. Research is focused on the application of
contemporary cellular and molecular biology to investigate the remodelling
of human skeletal and articular tissues. Specific emphasis is placed on the
development and application of techniques to culture bone and cartilage cells
of human origin. This is the largest research group in the region undertaking
osteoarticular research and consists of fifteen research staff who work in
close co-operation and collaboration with orthopaedic surgeons, rheumatologists
and other clinical colleagues throughout the Merseyside region. Funding is
from the research councils, medical charities and the pharmaceutical and
diagnostic industries.
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| | GROUP LEADER Jim Gallagher
| | Major research interests include culture of human osteoblasts and the
regulation of human bone remodelling (See:- Gallagher J.A., Gundle R.,
Beresford J.N. (1996) Isolation and Culture of Osteoblastic Cells from
Human Bone. In 'Human Cell Culture Protocols' Ed. G.E. Jones, Humana Press
Inc. pp 233-262 and Gallagher, J.A., Dillon J.P. (1997) Human Bone Remodeling.
In 'Encyclopaedia of Human Biology' 2nd Edition. Ed. R. Dulbecco, Academic
Press, In press).
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SENIOR SCIENTISTS
| Cathy Walsh
Human bone cell culture ( See Walsh C. A., Carron J.A., Gallagher J.A., (1996) Isolation of
osteoclasts from human giant cell tumour and long term marrow cultures. In
'Human Cell Culture Protocols' Ed. G.E. Jones, Humana Press Inc. pp 263-276).
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| | John Carron
Matrix proteins in cartilage and bone (See Carron J.A., Walsh C.A.,
Fraser W.D., Gallagher J.A. (1995) Thrombospondin promotes resorption by
osteoclasts in vitro. Biochimica Biophysica Research Communications 213:1017-1025).
| | WayneBowler Purinoceptors in
cartilage and bone (See Bowler, W.B., Birch, M.A., Gallagher, J.A., Bilbe G.
(1995) Identification and cloning of human P2U purinoceptor present in
osteoclastoma, bone and osteoblasts. Journal of Bone and Mineral Research
10: 1137-1145).
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This page was last updated by
John Carron on 18th November 1997
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