Email: ngreeves@liv.ac.uk
via Eudora Pro 2.1.4
TEL NOS:- DIRECT +44 (0)151 794 3506
Our research covers all aspects of organic synthesis, particularly the design, discovery, and development of new stereoselective reactions and the application of these synthetic methods to the construction of various biologically active natural products and structurally related molecules of interest. Opportunities exist for industrial collaboration with leading pharmaceutical companies on the testing of these materials.
Natural Product Synthesis
The development of concise synthetic routes to biologically important molecules using acyclic and macrocyclic stereocontrol strategies, supported by computer modelling, is the second complementary research area. Current synthetic targets include cytotoxic terpenes (Neoliacine - CASE award with Glaxo).
Selected Recent References
`Synthesis of Phenylthiomethyl Substituted Furans by Lewis Acid Catalysed Substitution,' Synthesis, 1993, 1109-1112.
`Regioselective and Stereoselective Palladium(0) Catalyzed Hydrostannation of Disubstituted Propargyl Alcohols', Synlett 1994, 537-538.