MTMR2 dimensional representation. Using structure viewer Cn3D program (http://www.ncbi.nlm.nih.gov/Structure /CN3D/cn3d) human MTMR2 is represented (amino acids 74-586, Begley et al). Right; PH-Gram domain (pink), Phosphatase domain (yellow) and missense disease mutations (blue) are shown. Based on Begley MJ et al. 2003