Papers in Peer-Reviewed Journals:
Thornton S, Coupland SE, Olohan L, Sibbring JS, Kenny JG,
Hertz-Fowler C, Liu X, Haldenby S, Heimann H, Hussain R, Kipling N, Taktak A,
Kalirai H. (doi: 10.3390/cancers12041039)
Targeted Next-Generation Sequencing of 117 Routine Clinical Samples Provides
Further Insights into the Molecular Landscape of Uveal Melanoma.
Cancers (Basel). 12(4). pii: E1039. (2020)
Damato B, Eleuteri A, Hussain R, Kalirai H, Thornton S, Taktak A,
Heimann H, Coupland SE. (doi:
10.1167/iovs.61.4.35)
Parsimonious Models for Predicting Mortality from Choroidal Melanoma.
Invest Ophthalmol Vis Sci. 61(4):35. (2020)
Cunha Rola A, Taktak A, Eleuteri A, Kalirai H, Heimann H, Hussain R,
Bonnett LJ, Hill CJ, Traynor M, Jager MJ, Marinkovic M, Luyten GPM, Dogrusöz M,
Kilic E, de Klein A, Smit K, van Poppelen NM, Damato BE, Afshar A, Guthoff RF,
Scheef BO, Kakkassery V, Saakyan S, Tsygankov A, Mosci C, Ligorio P, Viaggi S,
Le Guin CHD, Bornfeld N, Bechrakis NE, Coupland SE. (doi: 10.3390/cancers12020477)
Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator
Online: An OOG Collaborative Study.
Cancers (Basel);
12(2). pii: E477 (2020)
Hussain R, Czanner G, Taktak A, Damato B, Praidou A, Heimann H.
(DOI: 10.1097/IAE.0000000000002763)
Mortality of patients with uveal melanoma detected by diebetic retinopathy
screening.
Retina.
[Epub ahead of print] (2020)
Thornton S, Coupland SE, Heimann H, Hussain R, Groenewald C, Kacperek A, Damato
B, Taktak A, Eleuteri A, Kalirai H.
(doi:
10.1136/bjophthalmol-2019-315363)
Effects of plaque brachytherapy and proton beam radiotherapy on prognostic
testing: a comparison of uveal melanoma genotyped by microsatellite analysis.
Br J Ophthalmol. [Epub ahead of print]
(2020)
Kenawy N, Kalirai H, Sacco JJ, Lake SL, Heegaard S, Larsen AC, Finger PT, Milman
T, Chin K, Mosci C, Lanza F, Moulin A, Schmitt CA, Caujolle JP, Maschi C,
Marinkovic M, Taktak AF, Heimann H,
Damato BE, Coupland SE.
Conjunctival melanoma copy number alterations and correlation with mutation
status, tumor features, and clinical outcome.
Pigment, Cell and Melanoma Research,
Epub (2019)
A. Eleuteri, A.F.G. Taktak, S.E.
Coupland, H. Heimann, H. Kalirai, B.E. Damato (doi:
10.1016/j.compbiomed.2018.09.024)
Prognostication of metastatic death in uveal melanoma patients: A Markov
multi-state model. Computers in Biology
and Medicine, Epub (2018)
N. Farquhar, S. Thornton, S. E. Coupland, J. M. Coulson, J. J. Sacco, Y.
Krishna, H. Heimann, A. Taktak, C.
M. Cebulla, M. H. Abdul-Rahman, H. Kalirai (doi:
10.1002/cjp2.86)
Patterns of BAP1 protein expression provide insight into prognostic significance
and the biology of uveal melanoma The Journal of Pathology: Clinical
Research, pp 1-13, Online publication (2017).
M. Angi, H. Kalirai, A. Taktak, R.
Hussain, C. Groenewald, B. E. Damato, H. Heimann, S. E. Coupland (doi:
10.1136/bjophthalmol-2017-310361)
Prognostic biopsy of choroidal melanoma: an optimised surgical and laboratory
approach British Journal of Ophthalmology, 101, 8,
1143-1146 (2017).
S. E. Coupland, A. Taktak, B. E.
Damato (doi:
10.1001/jamaophthalmol.2017.1391)
Incorporating clinical, histological, and genetic parameters for choroidal
melanoma prognostication JAMA Ophthalmology, 135, 7, 818-819
(2017).
J. E. Medcalf, C. P. Johnson, A. Taktak,
S. Grabherr (doi:
10.1007/s12024-016-9819-4)
Variation in the anatomy of vertebral artery cervical loop segment - a potential
predisposing factor for traumatic basal subarachnoid hemorrhage? Forensic Sci
Med Pathol, 12 444-450 (2016).
S. W. DeParis, A. Taktak, A.
Eleuteri, W. Enanoria, H. Heimann, S. E. Coupland, B. E. Damato (doi:
10.1167/iovs.16-19654)
External validation of the Liverpool uveal melanoma progonsticator online,
Invest Ophthalmol Vis Sci, 57 6116-6122 (2016).
L. Ireland, A. Santos, M. S. Ahmed, C. Rainer, S. R. Nielsen, V. Quaranta, U.
Weyer-Czernilofski, D. D. Engle, P. A. Perez-Mancera, , S. E. Coupland,
A. Taktak, T. Bogenrieder, D. A.
Tuveson, F. Campbell, M. C. Schmid, A. Mielgo (doi:
10.1158/0008-5472.CAN-16-1201)
Chemoresistence in pancreatic cancer is driven by stroma-derived insulin-like
growth factors, Cancer Research, 76, 23 (2016).
S. Middle, S. E. Coupland, A. Taktak,
V. Kidgell, J. Slupsky, A. R. Pettitt, K. J. Till (doi:
10.1186/s40164-015-0004-3)
Immunohistochemical analysis indicates that the anatomical location of B-cell
non-Hodgkin's lymphoma is determined by differentially expressed chemokine
receptors, sphingosine-1-phosphate receptors and integrins, Experimental
Hematology & Oncology, 4, 10 (2015)
R. Caines, A. Eleuteri, H. Kalirai, A.C. Fisher, H. Heimann, B.E. Damato, S.E.
Coupland, A.F.G. Taktak (Link)
Cluster analysis of multiplex ligation-dependent probe amplification data in
choroidal melanoma, Molecular Vision, 21, 1-11 (2015)
A.F.G. Taktak
(Link)
Medical signal and information processing. Int J Biomedical Engineering and
Technology; Editorial. 13, 4, 301-302 (2013).
S.L. Lake, B. E. Damato, H. Kalirai, A.R. Dodson,
A.F.G. Taktak, B.H. Lloyd, S.E.
Coupland (doi:
10.1016/j.ajpath.2012.11.036)
Single nucleotide polymorphism array analysis of uveal melanomas reveals that
amplification of CNKSR3 is correlated with improved patient survival, Am J
Path, 182, 3, 678-687 (2013).
O.K. Idowu, Q. Ding, A.F.G. Taktak,
C.R. Chandrasekar, Q. Yin (doi:10.3109/1354750X.2012.699554)
Clinical implication of pre-treatment Nuetrophil lymphocyte ratio in soft tissue
sarcoma, Biomarkers, 17,6, 539-544 (2012).
F. Jmor, H. Kalirai, A.F.G. Taktak,
B. E. Damato, S.E. Coupland (doi:
10.1111/j.1755-3768.2010.02038.x)
HSP-27 protein expression in uveal melanoma: correlation with survival, Acta
Ophthalmologica, 90,6, 534-539 (2012).
A. Eleuteri, B.E. Damato, S.E. Coupland,
A.F.G. Taktak (Link)
Enhancing survival prognostication in patients with choroidal melanoma by
integrating pathologic, clinical and genetic predictors of metastasis. Int J
Biomedical Engineering and Technology, 8,1, 18-35 (2012).
S.L. Lake, F. Jmor, J. Dopierala, A.F.G.
Taktak, S.E. Coupland, B. E. Damato (doi:
10.1167/iovs.10-6934)
Multiplex ligation-dependent probe amplification of conjunctival melanoma
reveals common BRAF V600 gene mutation and gene copy number changes. Invest
Ophthalmol Vis Sci, 52,8 5598-5604 (2011).
S.L. Lake, B.E. Damato, J. Dopierala, M.M. Baudo,
A.F.G. Taktak, S.E. Coupland (doi:
10.1167/iovs.10-6845)
Multiplex ligation-dependent probe amplification analysis of uveal melanoma with
extraocular extension demonstrates heterogeneity of gross chromosomal
abnormalities. Invest Ophthalmol Vis Sci, 52,8, 55595564 (2011).
B.E. Damato, A. Eleuteri, A.F.G. Taktak,
S.E. Coupland (doi:
10:1016/j.preteyeres.2011.05.003)
Estimating prognosis for survival after treatment of choroidal melanoma. Prog
Retin Eye Res, 30,5, 285-295 (2011).
S. Harigopal, H.P. Satish, A.F.G. Taktak,
K.W.Southern, N.J. Shaw (doi:
10.1136/adc.2010.191437)
Oxygen saturation profiles in healthy preterm infants. Archives of Disease in
Childhood Fetal and Neonatal Edition, 96,5, F339-F342 (2011).
M. Angi, B. Damato, H. Kalirai, A. Dodson,
A. Taktak, S. Coupland (doi:
10.1111/j.1755-3768.2009.01769.x)
Immunohistochemical assessment of mitotic count in uveal melanoma. Acta
Ophtalmologica, 89, e155-e160 (2011)
J. Dopierala, B.E. Damato, S.L. Lake,
A.F.G. Taktak, S.E. Coupland (doi:
10.1167/iovs.09-5004)
Heterogeneity of genetic abnormalities in uveal melanoma assessed by multiplex
ligation-dependent probe amplification. Invest Ophthalmol Vis Sci.
51,10, 4898-4905 (2010).
S.L. Lake, S.E. Coupland, A.F.G. Taktak
and B.E. Damato. (doi:10.1167/iovs.09-5083)
Whole genome microarray detects deletions and loss of heterozygosity of
chromosome 3 occurring exclusively in metastasizing uveal melanoma. Invest
Ophthalmol Vis Sci. 51,10, 4884-4891 (2010).
R.N.G. Naguib, A.F.G. Taktak (Link)
Decision support in Medicine. Int J Biomedical Engineering and Technology;
Editorial. 3, 3/4, 209-211 (2010)
P.J.G. Lisboa, T.A. Etchells, I.H. Jarman, C.T. Arsene, M.S. Aung, A. Eleuteri,
A.F.G. Taktak, F. Ambrogi, P.
Boracchi, E. Biganzoli
(
doi:10.1109/TNN.2009.2023654)
Partial logistic artificial neural network for competing risks regularized with
automatic relevance determination. IEEE Transactions on Neural Networks,
20,9, 1403-1416 (2009)
A.F.G. Taktak,
A. Eleuteri, M.H. Aung, P.J.G. Lisboa, L. Desjardins, B.E. Damato
Survival analysis in cancer using partial logistic neural network model with
Bayesian regularisation framework: a validation study. Int J Knowledge
Engineering and Soft Data Paradigms, 1,3, 277-295 (2009)
B.E. Damato, A. Eleuteri, A.C. Fisher, S.E. Coupland and A.F.G.
Taktak (
doi:10.1016/j.ophtha.2008.01.032)
Artificial neural networks estimating survival probability after treatment of
choroidal melanoma. Ophthalmology, 115,9, 1598 - 1607 (2008)
A.F.G. Taktak,
A. Eleuteri, S.P. Lake, A.C. Fisher (doi:10.1016/j.compbiomed.2008.04.005)
A web-based tool for the assessment of discrimination and calibration properties
of prognostic models. Computers in Biology and Medicine, 38,7, pp
785-791 (2008)
A. Taktak,
L. Antolini, M. Aung, P. Boracchi, I. Campbell, B. Damato, E. Ifeachor, N. Lama,
P. Lisboa, C. Setzkorn, V. Stalbovskaya, E. Biganzoli (doi:10.1016/j.compbiomed.2006.10.001)
Double-blind evaluation and benchmarking of survival models in a multi-centre
study. Computers in Biology and Medicine, 37, pp 1108-1120 (2007)
C.Setzkorn, A. Taktak, B. Damato (doi:10.1016/j.biosystems.2006.03.002)
On the use of multi-objective evolutionary algorithms for survival analysis.
Biosystems, 87,1, pp 31-48 (2007)
A.C. Fisher, A.F.G. Taktak, R.P.
Hagan, M.C. Brown (doi:10.1007/s10633-006-9000-6)
Automated post hoc removal of power-line and frame-pulse contamination from
retinal and cortical evoked potentials (EPs). Documenta Ophthalmologica,
112, 169-175 (2006)
P.J.G. Lisboa, A.F.G. Taktak (doi:10.1016/j.neunet.2005.10.007)
The use of artificial neural networks in decision support in cancer: A
Systematic Review. Neural Networks, 19, pp 408-415 (2006).
A.S. Jones, A.F.G. Taktak, T.R.
Helliwell, J.E. Fenton, M.A. Birchall, D.J. Husband and A.C. Fisher (doi:10.1007/s00405-006-0021-2)
An artificial neural network improves prediction of observed survival in
patients with laryngeal squomous carcinoma. European Archives of
Oto-Rhino-Laryngology, 263, pp 541-547 (2006).
S.Y. Belal, A.F.G. Taktak, A. Nevill
and A. Spencer (doi:
10.1088/0967-3334/26/4/019)
An intelligent ventilation and oxygenation management system in neonatal
intensive care using fuzzy trend template fitting. Physiological Measurement,
26, pp 555-570 (2005).
A.F.G. Taktak,
A.C. Fisher and B.E. Damato (doi:
10.1088/0031-9155/49/1/006)
Modelling survival after treatment of intraocular melanoma using artificial
neural networks and Bayes theorem. Physics in Medicine and Biology, 49,1,
pp 87 – 98 (2004).
S. Belal, A. Taktak, A. Nevill, S.
Spencer, D. Roden and S. Bevan (doi:10.1016/S0933-3657(01)00099-9)
Automatic detection of distorted plethysmogram pulses in neonates and paediatric
patients using an adaptive-network-based fuzzy inference system. Artificial
Intelligence in Medicine, 24, pp 149-165 (2002).
S. Belal, A. Taktak, A. Nevill, S.
Spencer (doi:
10.1088/0967-3334/22/2/311)
A fuzzy system for detecting distorted plethysmogram pulses in neonates and
paediatric patients. Physiological Measurement, 22, 2,
pp397-412 (2001).
A. Taktak,
S. Simpson, S. Patel, G. Meyer (doi:
10.1088/0967-3334/21/3/401)
Neural networks analysis of oxygenation signals in infants during sleep.
Physiological Measurement, 21, 3, pp N11-N22, (2000).
A. Taktak,
P. Record, R. Gadd, P. Rolfe (doi:10.1016/1350-4533(95)00086-0)
Data recovery from reduced electrode connection in electrical impedance
tomography. Medical Engineering & Physics, 18, 6, pp
519-522 (1996).
A. Taktak,
A. Spencer, P. Record, R. Gadd, P. Rolfe (doi:10.1016/0378-3782(95)01700-3)
Feasibility of neonatal lung monitoring using electrical impedance tomography.
Early Human Development, vol 44, issue 2, pp 131-138
(1996).
P. Record, A. Taktak
Reproducibility of EIT images in vivo. Medical & Biological Engineering &
Computing; Editorial, 34, 5, p 344, (1996).
A. Taktak,
P. Record, R. Gadd, P. Rolfe
Interface impedance measurements of paediatric electrodes. Innovation et
Technologie en Biologie et Medicine, 16, 2, pp 126-135 (1995).
A. Taktak,
P. Record, R. Gadd, P. Rolfe
Practical factors in neonatal lung imaging using electrical impedance
tomography. Medical & Biological Engineering & Computing, 33 pp
202-205 (1995).