2022
Voronina, S., Chvanov, M., De Faveri, F., Mayer, U., Wileman, T., Criddle, D., & Tepikin, A. (2022). Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle. CELLS, 11(16). doi:10.3390/cells11162514DOI: 10.3390/cells11162514
2020
Chvanov, M., Voronina, S., Criddle, D. N., & Tepikin, A. V. (2020). The role of Ca2+ signalling in the physiology and pathophysiology of exocrine pancreas. Current Opinion in Physiology, 17, 96-105. doi:10.1016/j.cophys.2020.07.013DOI: 10.1016/j.cophys.2020.07.013
De Faveri, F., Chvanov, M., Voronina, S., Moore, D., Pollock, L., Haynes, L., . . . Tepikin, A. (2020). LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells. Autophagy, 16(7), 1314-1331. doi:10.1080/15548627.2019.1679514DOI: 10.1080/15548627.2019.1679514
Chvanov, M., Voronina, S., Zhang, X., Telnova, S., Chard, R., Ouyang, Y., . . . Tepikin, A. V. (2020). Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancreatitis. CELLS, 9(6). doi:10.3390/cells9061407DOI: 10.3390/cells9061407
2019
Goerguelue, K., Diakopoulos, K. N., Ai, J., Schoeps, B., Kabacaoglu, D., Karpathaki, A. -F., . . . Alguel, H. (2019). Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology, 156(1), 203-217e20. doi:10.1053/j.gastro.2018.09.053DOI: 10.1053/j.gastro.2018.09.053
2018
Tanton, H., Voronina, S., Evans, A., Armstrong, J., Sutton, R., Criddle, D. N., . . . Tepikin, A. V. (2018). F<sub>1</sub>F<sub>0</sub>-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation. FRONTIERS IN PHYSIOLOGY, 9. doi:10.3389/fphys.2018.00833DOI: 10.3389/fphys.2018.00833
Chvanov, M., De Faveri, F., Moore, D., Sherwood, M. W., Awais, M., Voronina, S., . . . Tepikin, A. V. (2018). Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis. JOURNAL OF PHYSIOLOGY, 596(13), 2547-2564. doi:10.1113/JP275879DOI: 10.1113/JP275879
2017
Szatmary, P., Liu, T., Abrams, S. T., Voronina, S., Wen, L., Chvanov, M., . . . Sutton, R. (2017). Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis. PANCREATOLOGY, 17(6), 884-892. doi:10.1016/j.pan.2017.10.002DOI: 10.1016/j.pan.2017.10.002
2016
Epithelial-mesenchymal transition, IP<sub>3</sub> receptors and ER-PM junctions: translocation of Ca<SUP>2+</SUP> signalling complexes and regulation of migration (Journal article)
Okeke, E., Parker, T., Dingsdale, H., Concannon, M., Awais, M., Voronina, S., . . . Tepikin, A. V. (2016). Epithelial-mesenchymal transition, IP<sub>3</sub> receptors and ER-PM junctions: translocation of Ca<SUP>2+</SUP> signalling complexes and regulation of migration. BIOCHEMICAL JOURNAL, 473, 757-767. doi:10.1042/BJ20150364DOI: 10.1042/BJ20150364
2015
Wen, L., Voronina, S., Javed, M. A., Awais, M., Szatmary, P., Latawiec, D., . . . Sutton, R. (2015). Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models. GASTROENTEROLOGY, 149(2), 481-492.e7. doi:10.1053/j.gastro.2015.04.015DOI: 10.1053/j.gastro.2015.04.015
The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells (Journal article)
Voronina, S., Collier, D., Chvanov, M., Middlehurst, B., Beckett, A., Prior, I., . . . Tepikin, A. V. (2015). The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells. Biochemical Journal, 465(3), 405-412. doi:10.1042/BJ20140398DOI: 10.1042/BJ20140398
An Efficient Method is Required to Transfect Non-dividing Cells with Genetically Encoded Optical Probes for Molecular Imaging (Journal article)
Awais, M., Voronina, S. G., & Sutton, R. (2015). An Efficient Method is Required to Transfect Non-dividing Cells with Genetically Encoded Optical Probes for Molecular Imaging. ANALYTICAL SCIENCES, 31(4), 293-298. doi:10.2116/analsci.31.293DOI: 10.2116/analsci.31.293
2014
How to win ATP and influence Ca<SUP>2+</SUP> signaling (Journal article)
Voronina, S., Okeke, E., Parker, T., & Tepikin, A. (2014). How to win ATP and influence Ca<SUP>2+</SUP> signaling. CELL CALCIUM, 55(3), 131-138. doi:10.1016/j.ceca.2014.02.010DOI: 10.1016/j.ceca.2014.02.010
2012
Cellular geography of IP<sub>3</sub> receptors, STIM and Orai: a lesson from secretory epithelial cells (Journal article)
Dingsdale, H., Voronina, S., Haynes, L., Tepikin, A., & Lur, G. (2012). Cellular geography of IP<sub>3</sub> receptors, STIM and Orai: a lesson from secretory epithelial cells. BIOCHEMICAL SOCIETY TRANSACTIONS, 40, 108-111. doi:10.1042/BST20110639DOI: 10.1042/BST20110639
Mitochondrial calcium in the life and death of exocrine secretory cells (Journal article)
Voronina, S., & Tepikin, A. (2012). Mitochondrial calcium in the life and death of exocrine secretory cells. CELL CALCIUM, 52(1), 86-92. doi:10.1016/j.ceca.2012.03.007DOI: 10.1016/j.ceca.2012.03.007
2010
Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells (Journal article)
Voronina, S. G., Barrow, S. L., Simpson, A. W. M., Gerasimenko, O. V., Xavier, G. D. S., Rutter, G. A., . . . Tepikin, A. V. (2010). Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells. GASTROENTEROLOGY, 138(5), 1976-U111. doi:10.1053/j.gastro.2010.01.037DOI: 10.1053/j.gastro.2010.01.037
2009
Modulation of calcium signalling by mitochondria (Journal article)
Walsh, C., Barrow, S., Voronina, S., Chvanov, M., Petersen, O. H., & Tepikin, A. (2009). Modulation of calcium signalling by mitochondria. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1787(11), 1374-1382. doi:10.1016/j.bbabio.2009.01.007DOI: 10.1016/j.bbabio.2009.01.007
Downstream from calcium signalling: mitochondria, vacuoles and pancreatic acinar cell damage (Journal article)
Voronina, S., Sherwood, M., Barrow, S., Dolman, N., Conant, A., & Tepikin, A. (2009). Downstream from calcium signalling: mitochondria, vacuoles and pancreatic acinar cell damage. ACTA PHYSIOLOGICA, 195(1), 161-169. doi:10.1111/j.1748-1716.2008.01931.xDOI: 10.1111/j.1748-1716.2008.01931.x
2008
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP (Journal article)
Chvanov, M., Walsh, C. M., Haynes, L. P., Voronina, S. G., Lur, G., Gerasimenko, O. V., . . . Tepikin, A. V. (2008). ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 457(2), 505-517. doi:10.1007/s00424-008-0529-yDOI: 10.1007/s00424-008-0529-y
ATP depletion inhibits Ca<SUP>2+</SUP> release, influx and extrusion in pancreatic acinar cells but not pathological Ca<SUP>2+</SUP> responses induced by bile (Journal article)
Barrow, S. L., Voronina, S. G., Xavier, G. D. S., Chvanov, M. A., Longbottom, R. E., Gerasimenko, O. V., . . . Tepikin, A. V. (2008). ATP depletion inhibits Ca<SUP>2+</SUP> release, influx and extrusion in pancreatic acinar cells but not pathological Ca<SUP>2+</SUP> responses induced by bile. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 455(6), 1025-1039. doi:10.1007/s00424-007-0360-xDOI: 10.1007/s00424-007-0360-x
2007
Visualizing formation and dynamics of vacuoles in living cells using contrasting dextran-bound indicator: endocytic and nonendocytic vacuoles (Journal article)
Voronina, S. G., Sherwood, M. W., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2007). Visualizing formation and dynamics of vacuoles in living cells using contrasting dextran-bound indicator: endocytic and nonendocytic vacuoles. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(6), G1333-G1338. doi:10.1152/ajpgi.00275.2007DOI: 10.1152/ajpgi.00275.2007
Calcium signalling and pancreatic cell death: apoptosis or necrosis? (Journal article)
Criddle, D. N., Gerasimenko, J. V., Baumgartner, H. K., Jaffar, M., Voronina, S., Sutton, R., . . . Gerasimenko, O. V. (2007). Calcium signalling and pancreatic cell death: apoptosis or necrosis?. CELL DEATH AND DIFFERENTIATION, 14(7), 1285-1294. doi:10.1038/sj.cdd.4402150DOI: 10.1038/sj.cdd.4402150
Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells (Journal article)
Sherwood, M. W., Prior, I. A., Voronina, S. G., Barrow, S. L., Woodsmith, J. D., Gerasimenko, O. V., . . . Tepikin, A. V. (2007). Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(13), 5674-5679. doi:10.1073/pnas.0700951104DOI: 10.1073/pnas.0700951104
2006
Bile acids induce Ca<SUP>2+</SUP> release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors (Journal article)
Gerasimenko, J. V., Flowerdew, S. E., Voronina, S. G., Sukhomlin, T. K., Tepikin, A. V., Petersen, O. H., & Gerasimenko, O. V. (2006). Bile acids induce Ca<SUP>2+</SUP> release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(52), 40154-40163. doi:10.1074/jbc.M606402200DOI: 10.1074/jbc.M606402200
Movement of calcium signals and calcium-binding proteins: firewalls, traps and tunnels (Journal article)
Barrow, S. L., Sherwood, M. W., Dolman, N. J., Gerasimenko, O. V., Voronina, S. G., & Tepikin, A. V. (2006). Movement of calcium signals and calcium-binding proteins: firewalls, traps and tunnels. BIOCHEMICAL SOCIETY TRANSACTIONS, 34, 381-384. doi:10.1042/BST0340381DOI: 10.1042/BST0340381
2005
Stable Golgi-mitochondria complexes and formation of Golgi Ca<SUP>2+</SUP> gradients in pancreatic acinar cells (Journal article)
Dolman, N. J., Gerasimenko, J. V., Gerasimenko, O. V., Voronina, S. G., Petersen, O. H., & Tepikin, A. V. (2005). Stable Golgi-mitochondria complexes and formation of Golgi Ca<SUP>2+</SUP> gradients in pancreatic acinar cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(16), 15794-15799. doi:10.1074/jbc.M412694200DOI: 10.1074/jbc.M412694200
Bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular Na<SUP>+</SUP> concentration (Journal article)
Voronina, S. G., Gryshchenko, O. V., Gerasimenko, O. V., Green, A. K., Petersen, O. H., & Tepikin, A. V. (2005). Bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular Na<SUP>+</SUP> concentration. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(3), 1764-1770. doi:10.1074/jbc.M410230200DOI: 10.1074/jbc.M410230200
Bile Acids Induce a Cationic Current, Depolarizing Pancreatic Acinar Cells and Increasing the Intracellular Na+ Concentration (Journal article)
Voronina, S. G., Gryshchenko, O. V., Gerasimenko, O. V., Green, A. K., Petersen, O. H., & Tepikin, A. V. (2005). Bile Acids Induce a Cationic Current, Depolarizing Pancreatic Acinar Cells and Increasing the Intracellular Na+ Concentration. Journal of Biological Chemistry, 280(3), 1764-1770. doi:10.1074/jbc.m410230200DOI: 10.1074/jbc.m410230200
2004
Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells -: Comparison of different modes of evaluating Δψ<sub>m</sub> (Journal article)
Voronina, S. G., Barrow, S. L., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2004). Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells -: Comparison of different modes of evaluating Δψ<sub>m</sub>. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(26), 27327-27338. doi:10.1074/jbc.M311698200DOI: 10.1074/jbc.M311698200
2002
Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology (Journal article)
Voronina, S., Longbottom, R., Sutton, R., Petersen, O. H., & Tepikin, A. (2002). Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology. JOURNAL OF PHYSIOLOGY-LONDON, 540(1), 49-55. doi:10.1113/jphysiol.2002.017525DOI: 10.1113/jphysiol.2002.017525
Correlation of NADH and Ca<sup>2+</sup> signals in mouse pancreatic acinar cells (Journal article)
Voronina, S., Sukhomlin, T., Johnson, P. R., Erdemli, G., Petersen, O. H., & Tepikin, A. (2002). Correlation of NADH and Ca<sup>2+</sup> signals in mouse pancreatic acinar cells. Journal of Physiology, 539(1), 41-52. doi:10.1113/jphysiol.2001.013134DOI: 10.1113/jphysiol.2001.013134
Correlation of NADH and Ca<SUP>2+</SUP> signals in mouse pancreatic acinar cells (Journal article)
Voronina, S., Sukhomlin, T., Johnson, P. R., Erdemli, G., Petersen, O. H., & Tepikin, A. (2002). Correlation of NADH and Ca<SUP>2+</SUP> signals in mouse pancreatic acinar cells. JOURNAL OF PHYSIOLOGY-LONDON, 539(1), 41-52. doi:10.1113/jphysiol.2001.013134DOI: 10.1113/jphysiol.2001.013134
1992
PULSATILE CA2+ EXTRUSION FROM SINGLE PANCREATIC ACINAR-CELLS DURING RECEPTOR-ACTIVATED CYTOSOLIC CA2+ SPIKING (Journal article)
TEPIKIN, A. V., VORONINA, S. G., GALLACHER, D. V., & PETERSEN, O. H. (1992). PULSATILE CA2+ EXTRUSION FROM SINGLE PANCREATIC ACINAR-CELLS DURING RECEPTOR-ACTIVATED CYTOSOLIC CA2+ SPIKING. JOURNAL OF BIOLOGICAL CHEMISTRY, 267(20), 14073-14076. Retrieved from https://www.webofscience.com/
ACETYLCHOLINE-EVOKED INCREASE IN THE CYTOPLASMIC CA2+ CONCENTRATION AND CA2+ EXTRUSION MEASURED SIMULTANEOUSLY IN SINGLE-MOUSE PANCREATIC ACINAR-CELLS (Journal article)
TEPIKIN, A. V., VORONINA, S. G., GALLACHER, D. V., & PETERSEN, O. H. (1992). ACETYLCHOLINE-EVOKED INCREASE IN THE CYTOPLASMIC CA2+ CONCENTRATION AND CA2+ EXTRUSION MEASURED SIMULTANEOUSLY IN SINGLE-MOUSE PANCREATIC ACINAR-CELLS. JOURNAL OF BIOLOGICAL CHEMISTRY, 267(6), 3569-3572. Retrieved from https://www.webofscience.com/
