Photo of Dr Ruwanthi Kolamunnage-Dona

Dr Ruwanthi Kolamunnage-Dona Ph.D

Reader in Medical Statistics Health Data Science

Publications

2021

Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children. (Journal article)

Nielsen, M. J., Baines, P., Jennings, R., Siner, S., Kolamunnage-Dona, R., Newland, P., . . . Carrol, E. D. (2021). Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children.. PLoS One, 16(2), e0246027. doi:10.1371/journal.pone.0246027

DOI: 10.1371/journal.pone.0246027

2020

Adjustment for the measurement error in evaluating biomarker performances at baseline for future survival outcomes: Time-dependent ROC curve within a joint modelling framework (Journal article)

Kolamunnage-Dona, R. (2020). Adjustment for the measurement error in evaluating biomarker performances at baseline for future survival outcomes: Time-dependent ROC curve within a joint modelling framework. Research Methods in Medicine & Health Sciences. doi:10.1177/2632084320972257

DOI: 10.1177/2632084320972257

Faster Monte Carlo estimation of joint models for time-to-event and multivariate longitudinal data (Journal article)

Philipson, P., Hickey, G. L., Crowther, M. J., & Kolamunnage-Dona, R. (2020). Faster Monte Carlo estimation of joint models for time-to-event and multivariate longitudinal data. Computational Statistics & Data Analysis, 151, 107010. doi:10.1016/j.csda.2020.107010

DOI: 10.1016/j.csda.2020.107010

Pharmacodynamics of the Novel Metallo-beta-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae (Journal article)

Das, S., Johnson, A., McEntee, L., Farrington, N., Kirby, A., Unsworth, J., . . . Hope, W. (2020). Pharmacodynamics of the Novel Metallo-beta-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 64(11). doi:10.1128/AAC.01076-20

DOI: 10.1128/AAC.01076-20

Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum (Journal article)

Bustinduy, A. L., Kolamunnage-Dona, R., Mirochnick, M. H., Capparelli, E. V., Tallo, V., Acosta, L. P., . . . Hope, W. W. (2020). Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64(9). doi:10.1128/AAC.00566-20

DOI: 10.1128/AAC.00566-20

Spatial Linear Mixed Effects Modelling for OCT Images: SLME Model (Journal article)

Zhu, W., Ku, J. Y., Zheng, Y., Knox, P. C., Kolamunnage-Dona, R., & Czanner, G. (n.d.). Spatial Linear Mixed Effects Modelling for OCT Images: SLME Model. Journal of Imaging, 6(6), 44. doi:10.3390/jimaging6060044

DOI: 10.3390/jimaging6060044

Treatment Outcomes of Incidental Intracranial Meningiomas: Results from the IMPACT Cohort (Journal article)

Islim, A. I., Mohan, M., Moon, R. D. C., Rathi, N., Kolamunnage-Dona, R., Crofton, A., . . . Jenkinson, M. D. (2020). Treatment Outcomes of Incidental Intracranial Meningiomas: Results from the IMPACT Cohort. WORLD NEUROSURGERY, 138, E725-E735. doi:10.1016/j.wneu.2020.03.060

DOI: 10.1016/j.wneu.2020.03.060

Spatial and spatio-temporal statistical analyses of retinal images: a review of methods and applications. (Journal article)

Zhu, W., Kolamunnage-Dona, R., Zheng, Y., Harding, S., & Czanner, G. (2020). Spatial and spatio-temporal statistical analyses of retinal images: a review of methods and applications.. BMJ open ophthalmology, 5(1), e000479. doi:10.1136/bmjophth-2020-000479

DOI: 10.1136/bmjophth-2020-000479

Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-beta-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae (Journal article)

Johnson, A., McEntee, L., Farrington, N., Kolamunnage-Dona, R., Franzoni, S., Vezzelli, A., . . . Hope, W. (2020). Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-beta-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64(6). doi:10.1128/AAC.00180-20

DOI: 10.1128/AAC.00180-20

TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy (Journal article)

Pushpakom, S. P., Kolamunnage-Dona, R., Taylor, C., Foster, T., Spowart, C., Garcia-Finana, M., . . . Pirmohamed, M. (n.d.). TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy. Clinical Infectious Diseases. doi:10.1093/cid/ciz589

DOI: 10.1093/cid/ciz589

Serum Levels of Alpha Fetoprotein Increased More Than 10 Years Before Detection of Hepatocellular Carcinoma (Journal article)

Hughes, D. M., Berhane, S., Emily de Groot, C. A., Toyoda, H., Tada, T., Kumada, T., . . . Johnson, P. (2020). Serum Levels of Alpha Fetoprotein Increased More Than 10 Years Before Detection of Hepatocellular Carcinoma. Clinical Gastroenterology and Hepatology. doi:10.1016/j.cgh.2020.04.084

DOI: 10.1016/j.cgh.2020.04.084

Bayesian joint modelling of longitudinal and time to event data: a methodological review (Journal article)

Alsefri, M., Sudell, M., García-Fiñana, M., & Kolamunnage-Dona, R. (2020). Bayesian joint modelling of longitudinal and time to event data: a methodological review. BMC Medical Research Methodology.

Clinical studies of incidental intracranial meningiomas-towards high-quality evidence-based practice (Journal article)

Islim, A. I., Millward, C. P., Martin-McGill, K. J., Kolamunnage-Dona, R., Santarius, T., Mathew, R. K., . . . Jenkinson, M. D. (2020). Clinical studies of incidental intracranial meningiomas-towards high-quality evidence-based practice. ACTA NEUROCHIRURGICA, 162(3), 673-674. doi:10.1007/s00701-020-04214-y

DOI: 10.1007/s00701-020-04214-y

A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas (Journal article)

Islim, A., Kolamunnage-Dona, R., Mohan, M., Moon, R., Crofton, A., Haylock, B., . . . Jenkinson, M. (2020). A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas. Neuro-Oncology, 22(2), 2278-289. doi:10.1093/neuonc/noz160

DOI: 10.1093/neuonc/noz160

Spatial Modelling of Retinal Thickness in Images from Patients with Diabetic Macular Oedema (Conference Paper)

Zhu, W., Ku, J. Y., Zheng, Y., Knox, P., Harding, S. P., Kolamunnage-Dona, R., & Czanner, G. (2020). Spatial Modelling of Retinal Thickness in Images from Patients with Diabetic Macular Oedema. In Unknown Conference (pp. 114-126). Springer International Publishing. doi:10.1007/978-3-030-39343-4_10

DOI: 10.1007/978-3-030-39343-4_10

2019

Biomarker-guided trials: Challenges in practice (Journal article)

Antoniou, M., Kolamunnage-Dona, R., Wason, J., Bathia, R., Billingham, C., Bliss, J. M., . . . Jorgensen, A. L. (2019). Biomarker-guided trials: Challenges in practice. Contemporary Clinical Trials Communications, 16, 100493. doi:10.1016/j.conctc.2019.100493

DOI: 10.1016/j.conctc.2019.100493

Estimating treatment effects in the presence of informative missingness (Conference Paper)

Kolamunnage-Dona, R. (2019). Estimating treatment effects in the presence of informative missingness. In TRIALS Vol. 20. Retrieved from http://gateway.webofknowledge.com/

Joint Modelling for longitudinal measures of marker CA19-9 and survival data in patients with pancreatic cancer (Conference Paper)

Cicconi, S., Ghaneh, P., Neoptolemos, J., Kolamunnage-Dona, R., & Jackson, R. (2019). Joint Modelling for longitudinal measures of marker CA19-9 and survival data in patients with pancreatic cancer. In TRIALS Vol. 20. Retrieved from http://gateway.webofknowledge.com/

Comparing results from one and two stage meta-analytic joint models (Poster)

Sudell, M. E., Kolamunnage-Dona, R., & Tudur Smith, C. (2019). Comparing results from one and two stage meta-analytic joint models. Poster session presented at the meeting of RSS 2019. Belfast.

Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT (Journal article)

Pushpakom, S., Kolamunnage-Dona, R., Taylor, C., Foster, T., Spowart, C., Garcia-Finana, M., . . . Pirmohamed, M. (2019). Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT.

DOI: 10.3310/eme06060

Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT (Journal article)

Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D. A., McKay, A., Rosala-Halas, A., . . . Grp, S. Y. C. A. M. O. R. E. S. (2019). Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT. HEALTH TECHNOLOGY ASSESSMENT, 23(15), 1-139. doi:10.3310/hta23150

DOI: 10.3310/hta23150

OPTIMISING OBSERVATION STRATEGIES FOR INCIDENTALLY DISCOVERED INTRACRANIAL MENINGIOMAS (Conference Paper)

Islim, A. I., Mohan, M., Moon, R. D. C., Mills, S. J., Brodbelt, A. R., Haylock, B. J., . . . Jenkinson, M. D. (2019). OPTIMISING OBSERVATION STRATEGIES FOR INCIDENTALLY DISCOVERED INTRACRANIAL MENINGIOMAS. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 90 (pp. E9-E10). doi:10.1136/jnnp-2019-ABN.29

DOI: 10.1136/jnnp-2019-ABN.29

Population Pharmacodynamics of Amphotericin B Deoxycholate for Disseminated Infection Caused by Talaromyces marneffei (Journal article)

Le, T., Ly, V. T., Thu, N. T. M., Nguyen, A., Thanh, N. T., Vinh Chau, N. V., . . . Hope, W. (2019). Population Pharmacodynamics of Amphotericin B Deoxycholate for Disseminated Infection Caused by Talaromyces marneffei. Antimicrobial Agents and Chemotherapy, 63(2). doi:10.1128/aac.01739-18

DOI: 10.1128/aac.01739-18

2018

Investigation of one-stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application (Journal article)

Sudell, M. E., Kolamunnage-Dona, R., Gueyffier, F., & Tudur Smith, C. (2018). Investigation of one-stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application. Statistics in Medicine, 38(2), 247-268. doi:10.1002/sim.7961

DOI: 10.1002/sim.7961

Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (vol 62, e02526-17, 2018) (Journal article)

Stott, K. E., Beardsley, J., Whalley, S., Kibengo, F. M., Mai, N. T. H., Tung, N. L. N., . . . Day, J. (2018). Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (vol 62, e02526-17, 2018). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(12). doi:10.1128/AAC.02249-18

DOI: 10.1128/AAC.02249-18

Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (vol 62, e00885-18, 2018) (Journal article)

Stott, K. E., Beardsley, J., Kolamunnage-Dona, R., Castelazo, A. S., Kibengo, F. M., Mai, N. T. H., . . . Hope, W. (2018). Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (vol 62, e00885-18, 2018). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62(12). doi:10.1128/AAC.02254-18

DOI: 10.1128/AAC.02254-18

A comparison of joint models for longitudinal and competing risks data, with application to an epilepsy drug randomized controlled trial (Journal article)

Hickey, G., Philipson, P., Jorgensen, A., & Kolamunnage-Dona, R. (2018). A comparison of joint models for longitudinal and competing risks data, with application to an epilepsy drug randomized controlled trial. Journal of the Royal Statistical Society Series A: Statistics in Society, 181(04), 1105-1123. doi:10.1111/rssa.12348

DOI: 10.1111/rssa.12348

Evaluation of time-dependent diagnostic efficacy of a baseline (Conference Paper)

Kolamunnage-Dona, R. (2018). Evaluation of time-dependent diagnostic efficacy of a baseline. In Diagnostic and Prognostic Research 2018 Vol. 2(Suppl 1):12 (pp. 16). Utrecht, The Netherlands.

Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis (Journal article)

Stott, K. E., Beardsley, J., Whalley, S., Kibengo, F. M., Mai, N. T. H., Tung, N. L. N., . . . Day, J. (2018). Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis. Antimicrobial agents and chemotherapy, 62(7). doi:10.1128/aac.02526-17

DOI: 10.1128/aac.02526-17

Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis (Journal article)

Stott, K. E., Beardsley, J., Kolamunnage-Dona, R., Santoyo Castelazo, A., Kibengo, F. M., Mai, N. T. H., . . . Hope, W. (2018). Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis. Antimicrobial Agents and Chemotherapy, 62(9). doi:10.1128/aac.00885-18

DOI: 10.1128/aac.00885-18

joineRML: a joint model and software package for time-to-event and multivariate longitudinal outcomes (Journal article)

Hickey, G. L., Philipson, P., Jorgensen, A., & Kolamunnage-Dona, R. (2018). joineRML: a joint model and software package for time-to-event and multivariate longitudinal outcomes. BMC MEDICAL RESEARCH METHODOLOGY, 18. doi:10.1186/s12874-018-0502-1

DOI: 10.1186/s12874-018-0502-1

Time-dependent efficacy of longitudinal biomarker for clinical endpoint (Journal article)

Kolamunnage-Dona, R., & Williamson, P. R. (2018). Time-dependent efficacy of longitudinal biomarker for clinical endpoint. Statistical Methods in Medical Research, 27(6), 1909-1924. doi:10.1177/0962280216673084

DOI: 10.1177/0962280216673084

Correction to: joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis (Journal article)

Sudell, M., Kolamunnage-Dona, R., & Tudur-Smith, C. (2018). Correction to: joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis. BMC MEDICAL RESEARCH METHODOLOGY, 18. doi:10.1186/s12874-018-0489-7

DOI: 10.1186/s12874-018-0489-7

Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus. (Journal article)

Negri, C. E., Johnson, A., McEntee, L., Box, H., Whalley, S., Schwartz, J. A., . . . Hope, W. W. (2018). Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus.. The Journal of infectious diseases, 217(7), 1118-1127. doi:10.1093/infdis/jix479

DOI: 10.1093/infdis/jix479

Statistical primer: performing repeated-measures analysis (Journal article)

Hickey, G. L., Mokhles, M., Chambers, D., & Kolamunnage-Dona, R. (2018). Statistical primer: performing repeated-measures analysis. Interactive CardioVascular and Thoracic Surgery, 26(4), 539-544. doi:10.1093/icvts/ivy009

DOI: 10.1093/icvts/ivy009

Investigation of two stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application (Journal article)

Sudell, M., Tudur Smith, C., Gueyffier, F., & Kolamunnage-Dona, R. (2018). Investigation of two stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application. Statistics in Medicine, 37(8), 1227-1244. doi:10.1002/sim.7585

DOI: 10.1002/sim.7585

Joint models of longitudinal and time-to-event data with more than one event time outcome: a review (Journal article)

Hickey, G. L., Philipson, P., Jorgensen, A., & Kolamunnage-Dona, R. (2018). Joint models of longitudinal and time-to-event data with more than one event time outcome: a review. The International Journal of Biostatistics, 14(1). doi:10.1515/ijb-2017-0047

DOI: 10.1515/ijb-2017-0047

2017

Fixed and Adaptive Parallel Subgroup-Specific Design for Survival Outcomes: Power and Sample Size (Journal article)

Antoniou, M., Jorgensen, A. L., & Kolamunnage-Dona, R. (2017). Fixed and Adaptive Parallel Subgroup-Specific Design for Survival Outcomes: Power and Sample Size. JOURNAL OF PERSONALIZED MEDICINE, 7(4). doi:10.3390/jpm7040019

DOI: 10.3390/jpm7040019

Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease. (Journal article)

Hope, W. W., McEntee, L., Livermore, J., Whalley, S., Johnson, A., Farrington, N., . . . Rex, J. H. (n.d.). Pharmacodynamics of the Orotomides against Aspergillus fumigatus: New Opportunities for Treatment of Multidrug-Resistant Fungal Disease.. mBio, 8(4). doi:10.1128/mbio.01157-17

DOI: 10.1128/mbio.01157-17

Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department (Journal article)

Irwin, A. D., Grant, A., Williams, R., Kolamunnage-Dona, R., Drew, R. J., Paulus, S., . . . Carrol, E. D. (2017). Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department. Pediatrics, 140(2), 0. doi:10.1542/peds.2016-2853

DOI: 10.1542/peds.2016-2853

Practical methods to pool multi-study joint longitudinal and time to event data (Conference Paper)

Sudell, M. E., Kolamunnage-Dona, R., & Tudur Smith, C. (2017). Practical methods to pool multi-study joint longitudinal and time to event data. In ISCB 2017. Vigo.

Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response (Journal article)

Kovanda, L. L., Kolamunnage-Dona, R., Neely, M., Maertens, J., Misun, L., & Hope, W. (2017). Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response. Clinical Infectious Diseases, 64(11), 1557-1563. doi:10.1093/cid/cix198

DOI: 10.1093/cid/cix198

Biomarker-guided clinical trial designs: sample size calculations with survival endpoints (Conference Paper)

Antoniou, M., Kolamunnage-Dona, R., & Jorgensen, A. L. (2017). Biomarker-guided clinical trial designs: sample size calculations with survival endpoints. In TRIALS Vol. 18. Retrieved from http://gateway.webofknowledge.com/

Time-dependent ROC curve analysis in medical research: current methods and applications (Journal article)

Kolamunnage-Dona, R., Cox, T., & Kamarudin, A. N. (2017). Time-dependent ROC curve analysis in medical research: current methods and applications. BMC Medical Research Methodology, 17. doi:10.1186/s12874-017-0332-6

DOI: 10.1186/s12874-017-0332-6

Methodology for analysis of joint longitudinal and time-to-event data from multiple studies (Conference Paper)

Sudell, M. E., Kolamunnage-Dona, R., & Tudur Smith, C. (2017). Methodology for analysis of joint longitudinal and time-to-event data from multiple studies. In Survival Analysis for Junior Researchers (SAfJR). University of Leicester.

Laparoscopy-assisted gastrectomy in the elderly: experience from a UK centre (Journal article)

Tandon, A., Rajendran, I., Aziz, M., Kolamunnage-Dona, R., Nunes, Q. M., & Shrotri, M. (2017). Laparoscopy-assisted gastrectomy in the elderly: experience from a UK centre. Annals of the Royal College of Surgeons of England, 99(4), 325-331. doi:10.1308/rcsann.2016.0344

DOI: 10.1308/rcsann.2016.0344

Incorporating the time-dependency in ROC methodology for censored clinical event (Conference Paper)

Kolamunnage-Dona, R. (2017). Incorporating the time-dependency in ROC methodology for censored clinical event. In Diagnostic and Prognostic Research 2017, 1(Suppl 1):7 (pp. 16). Birmingham, UK.

Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review (Journal article)

Antoniou, M., Kolamunnage-Dona, R., & Jorgensen, A. L. (2017). Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review. Journal of Personalized Medicine, 7(1). doi:10.3390/jpm7010001

DOI: 10.3390/jpm7010001

2016

Joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis (Journal article)

Sudell, M. E., Kolamunnage-Dona, R., & Tudur Smith, C. (2016). Joint models for longitudinal and time-to-event data: a review of reporting quality with a view to meta-analysis. BMC Medical Research Methodology, 16. doi:10.1186/s12874-016-0272-6

DOI: 10.1186/s12874-016-0272-6

A Randomized Controlled Trial of Extended Brief Intervention for Alcohol-Dependent Patients in an Acute Hospital Setting (Journal article)

Owens, L., Kolamunnage-Dona, R., Owens, A., Perkins, E., Butcher, G., Wilson, K., . . . Pirmohamed, M. (2016). A Randomized Controlled Trial of Extended Brief Intervention for Alcohol-Dependent Patients in an Acute Hospital Setting. Alcohol and Alcoholism, 51(05), 584-592. doi:10.1093/alcalc/agw023

DOI: 10.1093/alcalc/agw023

Joint modelling of time-to-event and multivariate longitudinal outcomes: recent developments and issues (Journal article)

Hickey, G. L., Philipson, P., Jorgensen, A., & Kolamunnage-Dona, R. (2016). Joint modelling of time-to-event and multivariate longitudinal outcomes: recent developments and issues. BMC Medical Research Methodology, 16. doi:10.1186/s12874-016-0212-5

DOI: 10.1186/s12874-016-0212-5

Modelling variable dropout in randomised controlled trials with longitudinal outcomes: Application to the MAGNETIC study (Journal article)

Kolamunnage-Dona, R., Powell, C., & Williamson, P. R. (2016). Modelling variable dropout in randomised controlled trials with longitudinal outcomes: Application to the MAGNETIC study. Trials, 17. doi:10.1186/s13063-016-1342-0

DOI: 10.1186/s13063-016-1342-0

Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review (Journal article)

Antoniou, M., Jorgensen, A. L., & Kolamunnage-Dona, R. (2016). Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review. PLoS One, 11(2). doi:10.1371/journal.pone.0149803

DOI: 10.1371/journal.pone.0149803

2015

Evaluating statistical characteristics of biomarker-guided trial designs (Journal article)

Antoniou, M., Jorgensen, A., & Kolamunnage-Dona, R. (2015). Evaluating statistical characteristics of biomarker-guided trial designs. TRIALS, 16. doi:10.1186/1745-6215-16-S2-O83

DOI: 10.1186/1745-6215-16-S2-O83

Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIVpositive individuals on combination antiretroviral therapy (Journal article)

Pushpakom, S., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcia Finana, M., . . . Pirmohamed, M. (2015). Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIVpositive individuals on combination antiretroviral therapy. BMJ Open, 5(10). doi:10.1136/bmjopen-2015-009566

DOI: 10.1136/bmjopen-2015-009566

2014

Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study (Journal article)

Swale, A., Miyajima, F., Kolamunnage-Dona, R., Roberts, P., Little, M., Beeching, N., . . . Pirmohamed, M. (2014). Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study. Clinical Infectious Diseases, 59(10), 1429-1436. doi:10.1093/cid/ciu666

DOI: 10.1093/cid/ciu666

ECONOMIC EVALUATION OF NEBULIZED MAGNESIUM SULPHATE IN ACUTE SEVERE ASTHMA IN CHILDREN (Journal article)

Petrou, S., Boland, A., Khan, K., Powell, C., Kolamunnage-Dona, R., Lowe, J., . . . Williamson, P. (2014). ECONOMIC EVALUATION OF NEBULIZED MAGNESIUM SULPHATE IN ACUTE SEVERE ASTHMA IN CHILDREN. INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE, 30(4), 354-360. doi:10.1017/S0266462314000440

DOI: 10.1017/S0266462314000440

Calprotectin and Lactoferrin Faecal Levels in Patients with Clostridium difficile Infection (CDI): A Prospective Cohort Study (Journal article)

Swale, A., Miyajima, F., Roberts, P., Hall, A., Little, M., Beadsworth, M., . . . Pirmohamed, M. (2014). Calprotectin and Lactoferrin Faecal Levels in Patients with Clostridium difficile Infection (CDI): A Prospective Cohort Study. PLoS One, 9(8). doi:10.1371/journal.pone.0106118

DOI: 10.1371/journal.pone.0106118

A review of the handling of missing longitudinal outcome data in clinical trials (Journal article)

Powney, M., Williamson, P., Kirkham, J., & Kolamunnage-Dona, R. (2014). A review of the handling of missing longitudinal outcome data in clinical trials. Trials, 15. doi:10.1186/1745-6215-15-237

DOI: 10.1186/1745-6215-15-237

Is the Interleukin 8 Promoter Polymorphism rs4073/–251T >A Associated With Clostridium difficile Infection? (Journal article)

Miyajima, F., Swale, A., Zhang, E., Alfirevic, A., Little, M., Beeching, N., . . . Pirmohamed, M. (2014). Is the Interleukin 8 Promoter Polymorphism rs4073/–251T >A Associated With Clostridium difficile Infection?. Clinical Infectious Disease, 58(12), e148-e151. doi:10.1093/cid/ciu152

DOI: 10.1093/cid/ciu152

Thoughts of self-harm and depression as prognostic factors in palliative care patients (Journal article)

Lloyd-Williams, M., Payne, S., Reeve, J., & Kolamunnage, D. R. (2014). Thoughts of self-harm and depression as prognostic factors in palliative care patients. Journal Affecitve Disorders, 166, 324-329. doi:10.1016/j.jad.2014.05.029

DOI: 10.1016/j.jad.2014.05.029

2013

Antidepressant medication in patients with advanced cancer--an observational study (Journal article)

Lloyd-Williams, M., Payne, S., Reeve, J., & Kolamunnage Dona, R. (2013). Antidepressant medication in patients with advanced cancer--an observational study. QJM, 106(11), 995-1001. doi:10.1093/qjmed/hct133

DOI: 10.1093/qjmed/hct133

Assessment and clinical course of hypocalcemia in critical illness (Journal article)

Steele, T., Kolamunnage-Dona, R., Downey, C., Toh, C. -H., & Welters, I. (2013). Assessment and clinical course of hypocalcemia in critical illness. CRITICAL CARE, 17(3). doi:10.1186/cc12756

DOI: 10.1186/cc12756

Magnesium sulphate in acute severe asthma in children (MAGNETIC): a randomised, placebo-controlled trial (Journal article)

Powell, C., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . Grp, M. A. G. N. E. T. I. C. S. (2013). Magnesium sulphate in acute severe asthma in children (MAGNETIC): a randomised, placebo-controlled trial. LANCET RESPIRATORY MEDICINE, 1(4), 301-308. doi:10.1016/S2213-2600(13)70037-7

DOI: 10.1016/S2213-2600(13)70037-7

A multistate modelling approach for pancreatic cancer development in genetically high-risk families (Journal article)

Kolamunnage-Dona, R., Vitone, L., Greenhalf, W., Henderson, R., & Williamson, P. R. (2013). A multistate modelling approach for pancreatic cancer development in genetically high-risk families. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 62(2), 201-212. doi:10.1111/j.1467-9876.2012.01051.x

DOI: 10.1111/j.1467-9876.2012.01051.x

Albumin-adjusted calcium concentration should not be used to identify hypocalcaemia in critical illness (Conference Paper)

Steele, T., Kolamunnage-Dona, R., Downey, C., Toh, C., & Welters, I. (2013). Albumin-adjusted calcium concentration should not be used to identify hypocalcaemia in critical illness. In Intensive Care and Emergency Medicine (pp. 1). Brussels: ICICEM.

Assessment and clinical course of hypocalcemia in critical illness. (Journal article)

Steele, T., Kolamunnage-Dona, R., Downey, C., Toh, C. H., & Welters, I. (2013). Assessment and clinical course of hypocalcemia in critical illness.. Critical Care, 17(3).

MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children. (Journal article)

Powell, C. V. E., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . MAGNETIC study group. (2013). MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children.. Health technology assessment (Winchester, England), 17(45), v-216. doi:10.3310/hta17450

DOI: 10.3310/hta17450

Time course of hyponatraemia in critical care (Conference Paper)

Nee, A. E., Welters, I. D., Steele, T., & Kolamunnage-Dona, R. (2013). Time course of hyponatraemia in critical care. In European Society of Intensive Care Medicine (pp. 1). 1820 Montreux: ESICM 2013.

2012

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children (Journal article)

Irwin, A. D., Marriage, F., Mankhambo, L. A., Group, I. P. D. S., Jeffers, G., Kolamunnage-Dona, R., . . . Carrol, E. D. (2012). Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children. BMC Medical Genomics, 5(1). doi:10.1186/1755-8794-5-13

DOI: 10.1186/1755-8794-5-13

MAGNESIUM TRIAL IN CHILDREN (MAGNETIC): A Randomised, Placebo Controlled Trial of Nebulised Magnesium Sulphate in Acute Severe Asthma in Children (Journal article)

Powell, C. V. E., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . on behalf of the MAGNETIC study group. (2012). MAGNESIUM TRIAL IN CHILDREN (MAGNETIC): A Randomised, Placebo Controlled Trial of Nebulised Magnesium Sulphate in Acute Severe Asthma in Children. Health Technology Assessment.

joineR: Joint modelling of repeated measurements and time-to-event data. (Software / Code)

Philipson, P., Sousa, I., Diggle, P., Williamson, P., Kolamunnage-Dona, R., & Henderson, R. (2012). joineR: Joint modelling of repeated measurements and time-to-event data. (Version 1) [Internet (free access)]. Comprehensive R Archive Network, United Kingdom.. Retrieved from http://cran.r-project.org/web/packages/joineR/index.html

2011

A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC) (Journal article)

Owens, L., Butcher, G., Gilmore, I., Kolamunnage-Dona, R., Oyee, J., Perkins, L., . . . Pirmohamed, M. (2011). A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). BMC PUBLIC HEALTH, 11. doi:10.1186/1471-2458-11-528

DOI: 10.1186/1471-2458-11-528

Brief Interventions in Dependent Drinkers: A Comparative Prospective Analysis in Two Hospitals (Journal article)

Cobain, K., Owens, L., Kolamunnage-Dona, R., Fitzgerald, R., Gilmore, I., & Pirmohamed, M. (2011). Brief Interventions in Dependent Drinkers: A Comparative Prospective Analysis in Two Hospitals. ALCOHOL AND ALCOHOLISM, 46(4), 434-440. doi:10.1093/alcalc/agr044

DOI: 10.1093/alcalc/agr044

Depressive and manic symptoms are not opposite poles in bipolar disorder (Journal article)

Johnson, S. L., Morriss, R., Scott, J., Paykel, E., Kinderman, P., Kolamunnage-Dona, R., & Bentall, R. P. (2011). Depressive and manic symptoms are not opposite poles in bipolar disorder. ACTA PSYCHIATRICA SCANDINAVICA, 123(3), 206-210. doi:10.1111/j.1600-0447.2010.01602.x

DOI: 10.1111/j.1600-0447.2010.01602.x

Investigating the effect of differential titration rates on efficacy and tolerability between new and standard drugs (Conference Paper)

Kolamunnage-Dona, R., Williamson, P., Philipson, P., & Marson, A. (2011). Investigating the effect of differential titration rates on efficacy and tolerability between new and standard drugs. In MRC North West Hub for Trials Methodology Research Showcase Meeting (pp. 1). Liverpool: MRC HUB.

Joint modelling of longitudinal and competing risks data (Conference Paper)

Kolamunnage-Dona, R., Williamson, P., Philipson, P., & Marson, A. (2011). Joint modelling of longitudinal and competing risks data. In IBS Channel Network Conference (pp. 1). Bordeaux: IBS Channel Network Conference.

Longitudinal and event time data: Medical section meeting. (Journal article)

Kolamaunnage-Doan, R. (2011). Longitudinal and event time data: Medical section meeting.. RSS NEWS, 39(4), 14.

2010

Assessing the potential for outcome reporting bias in a review: a tutorial (Journal article)

Dwan, K., Gamble, C., Kolamunnage-Dona, R., Mohammed, S., Powell, C., & Williamson, P. R. (2010). Assessing the potential for outcome reporting bias in a review: a tutorial. TRIALS, 11. doi:10.1186/1745-6215-11-52

DOI: 10.1186/1745-6215-11-52

Patients with epilepsy: Cognitively compromised before the start of antiepileptic drug treatment? (Journal article)

Taylor, J., Kolamunnage-Dona, R., Marson, A. G., Smith, P. E. M., Aldenkamp, A. P., Baker, G. A., & Grp, S. A. N. A. D. S. (2010). Patients with epilepsy: Cognitively compromised before the start of antiepileptic drug treatment?. EPILEPSIA, 51(1), 48-56. doi:10.1111/j.1528-1167.2009.02195.x

DOI: 10.1111/j.1528-1167.2009.02195.x

Enhanced relapse prevention for bipolar disorder by community mental health teams: cluster feasibility randomised trial (Journal article)

Lobban, F., Taylor, L., Chandler, C., Tyler, E., Kinderman, P., Kolamunnage-Dona, R., . . . Morriss, R. K. (2010). Enhanced relapse prevention for bipolar disorder by community mental health teams: cluster feasibility randomised trial. BRITISH JOURNAL OF PSYCHIATRY, 196(1), 59-63. doi:10.1192/bjp.bp.109.065524

DOI: 10.1192/bjp.bp.109.065524

Evaluation of Longitudinal Biomarkers (Conference Paper)

Kolamunnage-Dona, R., Williamson, P., Toh, C. H., Welters, I., & Downey, C. (2010). Evaluation of Longitudinal Biomarkers. In METHODS FOR EVALUATING MEDICAL TESTS AND BIOMARKERS: 2010 Symposium (pp. 37). Birmingham: University of Birmingham.

Prasugrel for the treatment of acute coronary artery syndromes with percutaneous coronary intervention (Journal article)

Greenhalgh, J., Bagust, A., Boland, A., Saborido, C. M., Fleeman, N., McLeod, C., . . . Fisher, M. (n.d.). Prasugrel for the treatment of acute coronary artery syndromes with percutaneous coronary intervention. Health Technology Assessment, 14(Suppl 1). doi:10.3310/hta14suppl1/05

DOI: 10.3310/hta14suppl1/05

SANAD study group. Patients with epilepsy: cognitively compromised before the start of antiepileptic drug treatment? (Journal article)

Taylor, J., Kolamunnage-Dona, R., Marson, A. G., Smith, P. E., Aldenkamp, A. P., & Baker, G. A. (2010). SANAD study group. Patients with epilepsy: cognitively compromised before the start of antiepileptic drug treatment?. Epilepsia, 51(1), 48-56.

2008

Joint modelling of longitudinal and competing risks data (Journal article)

Williamson, P. R., Kolamunnage-Dona, R., Philipson, R., & Marson, A. G. (2008). Joint modelling of longitudinal and competing risks data. STATISTICS IN MEDICINE, 27(30), 6426-6438. doi:10.1002/sim.3451

DOI: 10.1002/sim.3451

2007

The influence of competing-risks setting on the choice of hypothesis test for treatment effect (Journal article)

Williamson, P. R., Kolamunnage-Dona, R., & Smith, C. T. (2007). The influence of competing-risks setting on the choice of hypothesis test for treatment effect. BIOSTATISTICS, 8(4), 689-694. Retrieved from http://gateway.webofknowledge.com/

Joint modelling of competing risks in anti-epileptic drug trials and quality of life in epilepsy (Conference Paper)

Kolamunnage-Dona, R., Williamson, P. R., Gamble, C., Phillipson, P., Jacoby, A., & Marson, A. (2007). Joint modelling of competing risks in anti-epileptic drug trials and quality of life in epilepsy. In 28th Annual Conference of the International Society for Clinical Biostatistics (pp. 89). Greece: ISCB.

Modelling the association between diabetes onset and pancreatic cancer allowing for the competing risks of resection (Conference Paper)

Kolamunnage-Dona, R., Williamson, P. R., Henderson, R., & Vitone, L. (2007). Modelling the association between diabetes onset and pancreatic cancer allowing for the competing risks of resection. In 28th Annual Conference of the International Society for Clinical Biostatistics (pp. 189). Greece: ISCB.

2005

Analysing shape variation of biological objects (Thesis / Dissertation)

Kolamunnage-Dona, R. (2005). Analysing shape variation of biological objects. (PhD Thesis, University of Leeds).

Decomposing departures from bilateral symmetry (Chapter)

Kolamunnage-Dona, R., & Kent, J. T. (2005). Decomposing departures from bilateral symmetry. In S. Barber, P. D. Baxter, K. V. Mardia, & R. E. Walls (Eds.), Quantitative Biology, Shape Analysis and Wavelets (pp. 75-78). Leeds: Leeds University Press.

Visualising facial asymmetry (Conference Paper)

Kolamunnage-Dona, R. (2005). Visualising facial asymmetry. In Research Students Conference in Probability and Statistics (pp. 62). Cambridge: RSC.

2004

Symmetric and Asymmetric variation of Shape (Conference Paper)

Kolamunnage-Dona, R. (2004). Symmetric and Asymmetric variation of Shape. In International Sri Lankan Statistical Conference (pp. 253). Kandy: ISSC.

2003

PCA for Shape Variation about an Underlying Symmetric Shape (Chapter)

Kolamunnage-Dona, R., & Kent, J. T. (2003). PCA for Shape Variation about an Underlying Symmetric Shape. In R. G. Aykroyd, K. V. Mardia, & M. J. Langdon (Eds.), Stochastic Geometry, Biological Structure and Images (pp. 137-139). Leeds: Leeds University Press.

2002

Type I Progressively Censored variables-Sampling Plans in the Presence of Competing Risks (Thesis / Dissertation)

Kolamunnage-Dona, R. (2002). Type I Progressively Censored variables-Sampling Plans in the Presence of Competing Risks. (Master's Thesis, National University of Singapore).