Prof Andrew Morris BSc, MSc, PhD

Chair in Statistical Genetics Biostatistics

    Publications

    2019

    Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions. (Journal article)

    Nicoletti, P., Barrett, S., McEvoy, L., Daly, A. K., Aithal, G., Lucena, M. I., . . . Pirmohamed, M. (2019). Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions.. Clinical pharmacology and therapeutics. doi:10.1002/cpt.1493

    DOI: 10.1002/cpt.1493

    Genome-wide association study of type 2 diabetes in Africa (Journal article)

    Chen, J., Sun, M., Adeyemo, A., Pirie, F., Carstensen, T., Pomilla, C., . . . Motala, A. A. (2019). Genome-wide association study of type 2 diabetes in Africa. DIABETOLOGIA, 62(7), 1204-1211. doi:10.1007/s00125-019-4880-7

    DOI: 10.1007/s00125-019-4880-7

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (Journal article)

    Warrington, N. M., Beaumont, R. N., Horikoshi, M., Day, F. R., Helgeland, O., Laurin, C., . . . Consortium, E. G. G. (2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. NATURE GENETICS, 51(5), 804-+. doi:10.1038/s41588-019-0403-1

    DOI: 10.1038/s41588-019-0403-1

    Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (Journal article)

    Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., . . . Cohort, L. (2019). Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. NATURE GENETICS, 51(4), 636-+. doi:10.1038/s41588-019-0378-y

    DOI: 10.1038/s41588-019-0378-y

    New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (Journal article)

    Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., . . . Grp, U. S. S. (2019). New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. NATURE GENETICS, 51(3), 481-+. doi:10.1038/s41588-018-0321-7

    DOI: 10.1038/s41588-018-0321-7

    Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. (Journal article)

    Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., . . . Lindgren, C. M. (2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.. Nature genetics. doi:10.1038/s41588-018-0334-2

    DOI: 10.1038/s41588-018-0334-2

    Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia (Journal article)

    Gialluisi, A., Andlauer, T. F. M., Mirza-Schreiber, N., Moll, K., Becker, J., Hoffmann, P., . . . Schulte-Koerne, G. (2019). Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia. TRANSLATIONAL PSYCHIATRY, 9. doi:10.1038/s41398-019-0402-0

    DOI: 10.1038/s41398-019-0402-0

    Disentangling the genetics of lean mass. (Journal article)

    Karasik, D., Zillikens, M. C., Hsu, Y. -H., Aghdassi, A., Akesson, K., Amin, N., . . . Ohlsson, C. (2019). Disentangling the genetics of lean mass.. The American journal of clinical nutrition. doi:10.1093/ajcn/nqy272

    DOI: 10.1093/ajcn/nqy272

    Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation (Journal article)

    Doerr, M., Hamburg, N. M., Mueller, C., Smith, N. L., Gustafsson, S., Lehtimaeki, T., . . . Schnabel, R. B. (2019). Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. CIRCULATION-GENOMIC AND PRECISION MEDICINE, 12(2). doi:10.1161/CIRCGEN.118.002409

    DOI: 10.1161/CIRCGEN.118.002409

    Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. (Journal article)

    Morris, A. P., Le, T. H., Wu, H., Akbarov, A., van der Most, P. J., Hemani, G., . . . Franceschini, N. (2019). Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.. Nature communications, 10(1), 29. doi:10.1038/s41467-018-07867-7

    DOI: 10.1038/s41467-018-07867-7

    2018

    Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes (Journal article)

    Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., . . . Gromada, J. (2018). Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. NATURE COMMUNICATIONS, 9. doi:10.1038/s41467-018-04611-z

    DOI: 10.1038/s41467-018-04611-z

    Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity (Journal article)

    Marklund, M., Morris, A. P., Mahajan, A., Ingelsson, E., Lindgren, C. M., Lind, L., & Riserus, U. (2018). Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity. NUTRIENTS, 10(11). doi:10.3390/nu10111791

    DOI: 10.3390/nu10111791

    Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps (Journal article)

    Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., . . . McCarthy, M. I. (2018). Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. NATURE GENETICS, 50(11), 1505-+. doi:10.1038/s41588-018-0241-6

    DOI: 10.1038/s41588-018-0241-6

    Genome-wide association study in 404,165 individuals identifies 139 novel signals of association with lung function (Conference Paper)

    Shrine, N., Guyatt, A. L., Jackson, V. E., Erzurumluoglu, A. M., Morris, A. P., Hall, I. P., . . . Study, L. E. (2018). Genome-wide association study in 404,165 individuals identifies 139 novel signals of association with lung function. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 730-731). Retrieved from http://gateway.webofknowledge.com/

    Large-scale trans-ethnic genome-wide association study reveals novel loci, causal molecular mechanisms and effector genes for kidney function (Conference Paper)

    Franceschini, N., Le, T., Akbarov, A., Tomaszewski, M., Morris, A. P., & Consortium, C. -K. (2018). Large-scale trans-ethnic genome-wide association study reveals novel loci, causal molecular mechanisms and effector genes for kidney function. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 699). Retrieved from http://gateway.webofknowledge.com/

    Population stratification in the Estonian biobank and its confounding with complex traits (Conference Paper)

    Pervjakova, N., Lall, K., Mandul, M., Morris, A. P., Magi, R., & Fischer, K. (2018). Population stratification in the Estonian biobank and its confounding with complex traits. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 723). Retrieved from http://gateway.webofknowledge.com/

    Prediction of CpG methylation status from SNP genotype data (Conference Paper)

    Fryett, J. J., Morris, A. P., & Cordell, H. J. (2018). Prediction of CpG methylation status from SNP genotype data. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 699-700). Retrieved from http://gateway.webofknowledge.com/

    Trans-ethnic meta-analysis of gestational diabetes reveals shared genetic background with type 2 diabetes (Conference Paper)

    Pervjakova, N., Cook, J. P., Morris, A. P., Ferreira, T., Magi, R., & Consortium, G. (2018). Trans-ethnic meta-analysis of gestational diabetes reveals shared genetic background with type 2 diabetes. In GENETIC EPIDEMIOLOGY Vol. 42 (pp. 693-694). Retrieved from http://gateway.webofknowledge.com/

    Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (Journal article)

    Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsu, B., Pazoki, R., Gao, H., . . . Program, M. V. (2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. NATURE GENETICS, 50(10), 1412-+. doi:10.1038/s41588-018-0205-x

    DOI: 10.1038/s41588-018-0205-x

    Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry (Journal article)

    Pulit, S. L., Stoneman, C., Morris, A. P., Wood, A., Glastonbury, C. A., Tyrrell, J., . . . Consortium, G. I. A. N. T. (2019). Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. HUMAN MOLECULAR GENETICS, 28(1), 166-174. doi:10.1093/hmg/ddy327

    DOI: 10.1093/hmg/ddy327

    Comparison of methods for transcriptome imputation through application to two common complex diseases (Journal article)

    Fryett, J. J., Inshaw, J., Morris, A. P., & Cordell, H. J. (2018). Comparison of methods for transcriptome imputation through application to two common complex diseases. European Journal of Human Genetics, 26(11), 1658-1667. doi:10.1038/s41431-018-0176-5

    DOI: 10.1038/s41431-018-0176-5

    Multi-ethnic genome-wide association study for atrial fibrillation (Journal article)

    Roselli, C., Chaffin, M. D., Weng, L. -C., Aeschbacher, S., Ahlberg, G., Albert, C. M., . . . Ellinor, P. T. (2018). Multi-ethnic genome-wide association study for atrial fibrillation. NATURE GENETICS, 50(9), 1225-+. doi:10.1038/s41588-018-0133-9

    DOI: 10.1038/s41588-018-0133-9

    Progress in defining the genetic contribution to type 2 diabetes susceptibility. (Journal article)

    Morris, A. P. (2018). Progress in defining the genetic contribution to type 2 diabetes susceptibility.. Current opinion in genetics & development, 50, 41-51. doi:10.1016/j.gde.2018.02.003

    DOI: 10.1016/j.gde.2018.02.003

    Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses (Journal article)

    Painter, J. N., O'Mara, T. A., Morris, A. P., Cheng, T. H. T., Gorman, M., Martin, L., . . . Spurdle, A. B. (2018). Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. CANCER MEDICINE, 7(5), 1978-1987. doi:10.1002/cam4.1445

    DOI: 10.1002/cam4.1445

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (Journal article)

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., . . . Consortium, G. I. A. N. T. (2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. NATURE GENETICS, 50(4), 559-+. doi:10.1038/s41588-018-0084-1

    DOI: 10.1038/s41588-018-0084-1

    Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition (Journal article)

    Small, K. S., Todorcevic, M., Civelek, M., Moustafa, J. S. E. -S., Wang, X., Simon, M. M., . . . McCarthy, M. I. (2018). Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. NATURE GENETICS, 50(4), 572-+. doi:10.1038/s41588-018-0088-x

    DOI: 10.1038/s41588-018-0088-x

    A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia (Journal article)

    Chen, X., Gustafsson, S., Whitington, T., Borne, Y., Lorentzen, E., Sun, J., . . . Magnusson, P. K. E. (2018). A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia. HUMAN MOLECULAR GENETICS, 27(10), 1809-1818. doi:10.1093/hmg/ddy094

    DOI: 10.1093/hmg/ddy094

    Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (Journal article)

    Malik, R., Chauhan, G., Traylor, M., Sargurupremraj, M., Okada, Y., Mishra, A., . . . Consortium, M. E. G. A. S. T. R. O. K. E. (2018). Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. NATURE GENETICS, 50(4), 524-+. doi:10.1038/s41588-018-0058-3

    DOI: 10.1038/s41588-018-0058-3

    Progress in defining the genetic contribution to type 2 diabetes susceptibility (Journal article)

    Morris, A. P. (2018). Progress in defining the genetic contribution to type 2 diabetes susceptibility. CURRENT OPINION IN GENETICS & DEVELOPMENT, 50, 41-51. doi:10.1016/j.gde.2018.02.003

    DOI: 10.1016/j.gde.2018.02.003

    A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure (Journal article)

    Sung, Y. J., Winkler, T. W., de las Fuentes, L., Bentley, A. R., Brown, M. R., Kraja, A. T., . . . Study, L. C. (2018). A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. AMERICAN JOURNAL OF HUMAN GENETICS, 102(3), 375-400. doi:10.1016/j.ajhg.2018.01.015

    DOI: 10.1016/j.ajhg.2018.01.015

    Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (vol 4, 170179, 2017) (Journal article)

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., . . . McCarthy, M. I. (2018). Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (vol 4, 170179, 2017). SCIENTIFIC DATA, 5. doi:10.1038/sdata.2018.2

    DOI: 10.1038/sdata.2018.2

    Meta-analysis of exome array data identifies six novel genetic loci for lung function (Journal article)

    Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., . . . London, S. J. (n.d.). Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Research, 3, 4. doi:10.12688/wellcomeopenres.12583.1

    DOI: 10.12688/wellcomeopenres.12583.1

    Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees (Journal article)

    Jun, G., Manning, A., Almeida, M., Zawistowski, M., Wood, A. R., Teslovich, T. M., . . . Blangero, J. (2018). Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(2), 379-384. doi:10.1073/pnas.1705859115

    DOI: 10.1073/pnas.1705859115

    A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood (Journal article)

    Jiang, J., Thalamuthu, A., Ho, J. E., Mahajan, A., Ek, W. E., Brown, D. A., . . . Mather, K. A. (2018). A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. FRONTIERS IN GENETICS, 9. doi:10.3389/fgene.2018.00097

    DOI: 10.3389/fgene.2018.00097

    Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders (Journal article)

    Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., . . . Grp, C. H. A. R. G. E. I. W. (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. AMERICAN JOURNAL OF HUMAN GENETICS, 103(5), 691-706. doi:10.1016/j.ajhg.2018.09.009

    DOI: 10.1016/j.ajhg.2018.09.009

    Genome-Wide Association Study in 404,165 Individuals Identifies 139 Novel Signals of Association with Lung Function (Conference Paper)

    Wain, L. V., Shrine, N., Guyatt, A. L., Jackson, V. E., Erzurumluoglu, A. M., Batini, C., . . . Study, L. E. (2018). Genome-Wide Association Study in 404,165 Individuals Identifies 139 Novel Signals of Association with Lung Function. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 197. Retrieved from http://gateway.webofknowledge.com/

    Meta-analysis of exome array data identifies six novel genetic loci for lung function. (Journal article)

    Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., . . . London, S. J. (2018). Meta-analysis of exome array data identifies six novel genetic loci for lung function.. Wellcome open research, 3, 4. doi:10.12688/wellcomeopenres.12583.3

    DOI: 10.12688/wellcomeopenres.12583.3

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Journal article)

    Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., . . . Grp, U. S. S. (2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. NATURE GENETICS, 50(1), 26-+. doi:10.1038/s41588-017-0011-x

    DOI: 10.1038/s41588-017-0011-x

    2017

    Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (Journal article)

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., . . . McCarthy, M. I. (2017). Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. SCIENTIFIC DATA, 4. doi:10.1038/sdata.2017.179

    DOI: 10.1038/sdata.2017.179

    Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues (Journal article)

    Rahmioglu, N., Drong, A. W., Lockstone, H., Tapmeier, T., Hellner, K., Saare, M., . . . Zondervan, K. T. (2017). Variability of genome-wide DNA methylation and mRNA expression profiles in reproductive and endocrine disease related tissues. EPIGENETICS, 12(10), 897-908. doi:10.1080/15592294.2017.1367475

    DOI: 10.1080/15592294.2017.1367475

    Genome-Wide Association Study Links Variants With Occurrence of Cardiovascular Events in People Taking the COX-2 Inhibitor Celecoxib: Identification of NCKX2 as a Novel Protective Pathway in Renal Vessels (Conference Paper)

    Kirkby, N. S., Morris, A. P., Lytton, J., Seong, J. K., Bae, Y. S., Chu, J. H., . . . Mitchell, J. A. (2017). Genome-Wide Association Study Links Variants With Occurrence of Cardiovascular Events in People Taking the COX-2 Inhibitor Celecoxib: Identification of NCKX2 as a Novel Protective Pathway in Renal Vessels. In CIRCULATION Vol. 136. Retrieved from http://gateway.webofknowledge.com/

    Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (vol 8, 80, 2017) (Journal article)

    Zillikens, M. C., Demissie, S., Hsu, Y. -H., Yerges-Armstrong, L. M., Chou, W. -C., Stolk, L., . . . Kiel, D. P. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (vol 8, 80, 2017). NATURE COMMUNICATIONS, 8. doi:10.1038/s41467-017-01008-2

    DOI: 10.1038/s41467-017-01008-2

    Comparison of methods for transcriptome imputation through application to two common complex diseases (Conference Paper)

    Fryett, J. J., Inshaw, J., Morris, A. P., & Cordell, H. J. (2018). Comparison of methods for transcriptome imputation through application to two common complex diseases. In EUROPEAN JOURNAL OF HUMAN GENETICS Vol. 26 (pp. 1658-1667). doi:10.1038/s41431-018-0176-5

    DOI: 10.1038/s41431-018-0176-5

    Development and Application of Methodology for the Analysis of Rare Genetic Variants with Time to Event Outcomes Using SurvivalGWAS_RV (Conference Paper)

    Syed, H., Jorgensen, A. L., & Morris, A. P. (2017). Development and Application of Methodology for the Analysis of Rare Genetic Variants with Time to Event Outcomes Using SurvivalGWAS_RV. In GENETIC EPIDEMIOLOGY Vol. 41 (pp. 685-686). Retrieved from http://gateway.webofknowledge.com/

    Discovery and Fine-Mapping of Type 2 Diabetes Susceptibility Loci Across Diverse Populations (Conference Paper)

    Below, J. E., Kitajima, H., Mahajan, A., Sim, X., Ng, M., Zhang, W., . . . Consortium, D. I. A. M. A. N. T. E. (2017). Discovery and Fine-Mapping of Type 2 Diabetes Susceptibility Loci Across Diverse Populations. In GENETIC EPIDEMIOLOGY Vol. 41 (pp. 650). Retrieved from http://gateway.webofknowledge.com/

    Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation (Journal article)

    Strawbridge, R. J., Silveira, A., den Hoed, M., Gustafsson, S., Luan, J., Rybin, D., . . . Grp, I. M. P. R. O. V. E. S. (2017). Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. ATHEROSCLEROSIS, 266, 196-204. doi:10.1016/j.atherosclerosis.2017.09.031

    DOI: 10.1016/j.atherosclerosis.2017.09.031

    Exome-wide association study of plasma lipids in > 300,000 individuals (Journal article)

    Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., . . . Program, V. A. M. V. (2017). Exome-wide association study of plasma lipids in > 300,000 individuals. NATURE GENETICS, 49(12), 1758-+. doi:10.1038/ng.3977

    DOI: 10.1038/ng.3977

    IDENTIFICATION OF GENETIC INTERACTIONS INVOLVED IN DYSLEXIA PATHOGENESIS (Conference Paper)

    Karbalai, N., Czamara, D., Moll, K., Ramus, F., Malik, R., Scerri, T. S., . . . Muller-Myhsok, B. (2017). IDENTIFICATION OF GENETIC INTERACTIONS INVOLVED IN DYSLEXIA PATHOGENESIS. In EUROPEAN NEUROPSYCHOPHARMACOLOGY Vol. 27 (pp. S183-S184). Retrieved from http://gateway.webofknowledge.com/

    New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals (Journal article)

    Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., . . . Co, U. K. B. C. -M. T. (2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals. CIRCULATION-CARDIOVASCULAR GENETICS, 10(5). doi:10.1161/CIRCGENETICS.117.001778

    DOI: 10.1161/CIRCGENETICS.117.001778

    Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution (Journal article)

    Magi, R., Horikoshi, M., Sofer, T., Mahajan, A., Kitajima, H., Franceschini, N., . . . Consortium, T. -G. (2017). Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution. HUMAN MOLECULAR GENETICS, 26(18), 3639-3650. doi:10.1093/hmg/ddx280

    DOI: 10.1093/hmg/ddx280

    Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry (Journal article)

    Sapkota, Y., De Vivo, I., Steinthorsdottir, V., Fassbender, A., Bowdler, L., Buring, J. E., . . . Grp, I. -S. -B. (2017). Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-10440-9

    DOI: 10.1038/s41598-017-10440-9

    Discovery and fine-mapping of type 2 diabetes susceptibility loci across diverse population (Conference Paper)

    Kitajima, H., Mahajan, A., Sim, X., Ng, M. C., Zhang, W., Below, J. E., . . . Consortium, D. I. A. M. A. N. T. E. (2017). Discovery and fine-mapping of type 2 diabetes susceptibility loci across diverse population. In DIABETOLOGIA Vol. 60 (pp. S8). Retrieved from http://gateway.webofknowledge.com/

    Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis (Journal article)

    Wheeler, E., Leong, A., Liu, C. -T., Hivert, M. -F., Strawbridge, R. J., Podmore, C., . . . Study, L. C. (2017). Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLOS MEDICINE, 14(9). doi:10.1371/journal.pmed.1002383

    DOI: 10.1371/journal.pmed.1002383

    Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney (Journal article)

    Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., . . . Grp, U. S. S. (2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. HYPERTENSION, 70(3), E4-+. doi:10.1161/HYPERTENSIONAHA.117.09438

    DOI: 10.1161/HYPERTENSIONAHA.117.09438

    Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. (Journal article)

    Zillikens, M. C., Demissie, S., Hsu, Y. -H., Yerges-Armstrong, L. M., Chou, W. -C., Stolk, L., . . . Kiel, D. P. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. NATURE COMMUNICATIONS, 8. doi:10.1038/s41467-017-00031-7

    DOI: 10.1038/s41467-017-00031-7

    Genetic loci associated with heart rate variability and their effects on cardiac disease risk. (Journal article)

    Nolte, I. M., Munoz, M. L., Tragante, V., Amare, A. T., Jansen, R., Vaez, A., . . . de Geus, E. J. C. (2017). Genetic loci associated with heart rate variability and their effects on cardiac disease risk. NATURE COMMUNICATIONS, 8. doi:10.1038/ncomms15805

    DOI: 10.1038/ncomms15805

    Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. (Journal article)

    Shungin, D., Deng, W. Q., Varga, T. V., Luan, J., Mihailov, E., Metspalu, A., . . . Consortium, G. I. A. N. T. (2017). Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLOS GENETICS, 13(6). doi:10.1371/journal.pgen.1006812

    DOI: 10.1371/journal.pgen.1006812

    Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel (Journal article)

    Mitt, M., Kals, M., Parn, K., Gabriel, S. B., Lander, E. S., Palotie, A., . . . Palta, P. (2017). Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel. EUROPEAN JOURNAL OF HUMAN GENETICS, 25(7), 869-876. doi:10.1038/ejhg.2017.51

    DOI: 10.1038/ejhg.2017.51

    An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. (Journal article)

    Scott, R. A., Scott, L. J., Maegi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., . . . Replicat, D. G. (2017). An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. DIABETES, 66(11), 2888-2902. doi:10.2337/db16-1253

    DOI: 10.2337/db16-1253

    A rare-variant test for high-dimensional data. (Journal article)

    Kaakinen, M., Magi, R., Fischer, K., Heikkinen, J., Jarvelin, M. -R., Morris, A. P., & Prokopenko, I. (2017). A rare-variant test for high-dimensional data. EUROPEAN JOURNAL OF HUMAN GENETICS, 25(8), 988-994. doi:10.1038/ejhg.2017.90

    DOI: 10.1038/ejhg.2017.90

    Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. (Journal article)

    Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., . . . Grp, I. -S. -B. (2017). Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. NATURE COMMUNICATIONS, 8. doi:10.1038/ncomms15539

    DOI: 10.1038/ncomms15539

    Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. (Journal article)

    Tachmazidou, I., Suveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., . . . UK10KConsortium. (2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. AMERICAN JOURNAL OF HUMAN GENETICS, 100(6), 865-884. doi:10.1016/j.ajhg.2017.04.014

    DOI: 10.1016/j.ajhg.2017.04.014

    SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes. (Journal article)

    Syed, H., Jorgensen, A. L., & Morris, A. P. (2017). SurvivalGWAS_SV: software for the analysis of genome-wide association studies of imputed genotypes with "time-to-event" outcomes. BMC BIOINFORMATICS, 18. doi:10.1186/s12859-017-1683-z

    DOI: 10.1186/s12859-017-1683-z

    Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children (Journal article)

    Windholz, J., Kovacs, P., Schlicke, M., Franke, C., Mahajan, A., Morris, A. P., . . . Koerner, A. (2017). Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 30(5), 507-515. doi:10.1515/jpem-2016-0435

    DOI: 10.1515/jpem-2016-0435

    Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function (Journal article)

    Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M. -H., Leening, M. J. G., . . . Investigators, K. N. H. I. (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. JOURNAL OF CLINICAL INVESTIGATION, 127(5), 1798-1812. doi:10.1172/JCI84840

    DOI: 10.1172/JCI84840

    Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. (Journal article)

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., . . . Cupples, L. A. (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. NATURE COMMUNICATIONS, 8. doi:10.1038/ncomms14977

    DOI: 10.1038/ncomms14977

    Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. (Journal article)

    Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., . . . Consortium, A. (2017). Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. NATURE GENETICS, 49(6), 946-+. doi:10.1038/ng.3843

    DOI: 10.1038/ng.3843

    Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel. (Journal article)

    Mitt, M., Kals, M., Parn, K., Gabriel, S. B., Lander, E. S., Palotie, A., . . . Palta, P. (2016). Improved Imputation Accuracy of Rare and Low-Frequency Genetic Variants Using Population-Specific High-Coverage Whole-Genome Sequencing Data Based Imputation Reference Panel. HUMAN HEREDITY, 81(4), 235. Retrieved from http://gateway.webofknowledge.com/

    DOI: 10.1038/ejhg.2017.51

    Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. (Journal article)

    Folkersen, L., Fauman, E., Sabater-Lleal, M., Strawbridge, R. J., Franberg, M., Sennblad, B., . . . Grp, I. M. P. R. O. V. E. S. (2017). Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PLOS GENETICS, 13(4). doi:10.1371/journal.pgen.1006706

    DOI: 10.1371/journal.pgen.1006706

    Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population (Journal article)

    Carr, D. F., Bourgeois, S., Chaponda, M., Takeshita, L. Y., Morris, A. P., Castro, E. M. C., . . . Pirmohamed, M. (2017). Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72(4), 1152-1162. doi:10.1093/jac/dkw545

    DOI: 10.1093/jac/dkw545

    A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. (Journal article)

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., . . . Lindgren, C. M. (2017). A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. DIABETES, 66(7), 2019-2032. doi:10.2337/db16-1329

    DOI: 10.2337/db16-1329

    Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (Journal article)

    Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., . . . Grp, U. S. S. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. NATURE GENETICS, 49(3), 403-415. doi:10.1038/ng.3768

    DOI: 10.1038/ng.3768

    Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal (Journal article)

    Parra, E. J., Mazurek, A., Gignoux, C. R., Sockell, A., Agostino, M., Morris, A. P., . . . Cruz, M. (2017). Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal. PLOS ONE, 12(2). doi:10.1371/journal.pone.0172880

    DOI: 10.1371/journal.pone.0172880

    MARV: a tool for genome-wide multi-phenotype analysis of rare variants (Journal article)

    Kaakinen, M., Magi, R., Fischer, K., Heikkinen, J., Jarvelin, M. -R., Morris, A. P., & Prokopenko, I. (2017). MARV: a tool for genome-wide multi-phenotype analysis of rare variants. BMC BIOINFORMATICS, 18. doi:10.1186/s12859-017-1530-2

    DOI: 10.1186/s12859-017-1530-2

    Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. (Journal article)

    Uimari, O., Rahmioglu, N., Nyholt, D. R., Vincent, K., Missmer, S. A., Becker, C., . . . Zondervan, K. T. (2017). Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. HUMAN REPRODUCTION, 32(4), 780-793. doi:10.1093/humrep/dex024

    DOI: 10.1093/humrep/dex024

    Rare and low-frequency coding variants alter human adult height (Journal article)

    Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., . . . Investigators, M. A. G. I. C. (2017). Rare and low-frequency coding variants alter human adult height. NATURE, 542(7640), 186-190. doi:10.1038/nature21039

    DOI: 10.1038/nature21039

    Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Journal article)

    Wain, L. V., Shrine, N., Artigas, M. S., Erzurumluoglu, A. M., Noyvert, B., Bossini-Castillo, L., . . . DiscovEHR, G. -R. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. NATURE GENETICS, 49(3), 416-425. doi:10.1038/ng.3787

    DOI: 10.1038/ng.3787

    Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes (Journal article)

    Cook, J. P., Mahajan, A., & Morris, A. P. (2017). Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes. EUROPEAN JOURNAL OF HUMAN GENETICS, 25(2), 240-245. doi:10.1038/ejhg.2016.150

    DOI: 10.1038/ejhg.2016.150

    SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes (Journal article)

    Magi, R., Suleimanov, Y. V., Clarke, G. M., Kaakinen, M., Fischer, K., Prokopenko, I., & Morris, A. P. (2017). SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes. BMC BIOINFORMATICS, 18. doi:10.1186/s12859-016-1437-3

    DOI: 10.1186/s12859-016-1437-3

    Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis (Journal article)

    van Rooij, F. J. A., Qayyum, R., Smith, A. V., Zhou, Y., Trompet, S., Tanaka, T., . . . Project, B. J. (2017). Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. AMERICAN JOURNAL OF HUMAN GENETICS, 100(1), 51-63. doi:10.1016/j.ajhg.2016.11.016

    DOI: 10.1016/j.ajhg.2016.11.016

    Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p '-dde levels in a population-based sample (Journal article)

    Lind, L., Ng, E., Ingelsson, E., Lindgren, C., Salihovic, S., van Bavel, B., . . . Lind, P. M. (2017). Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p '-dde levels in a population-based sample. ENVIRONMENT INTERNATIONAL, 98, 212-218. doi:10.1016/j.envint.2016.11.010

    DOI: 10.1016/j.envint.2016.11.010

    Improving Gene Expression Prediction Accuracy in Transcriptome-Wide Association Studies (Conference Paper)

    Fryett, J. J., Morris, A. P., & Cordell, H. J. (2017). Improving Gene Expression Prediction Accuracy in Transcriptome-Wide Association Studies. In HUMAN HEREDITY Vol. 83 (pp. 8). Retrieved from http://gateway.webofknowledge.com/

    Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation (Journal article)

    Chu, A. Y., Deng, X., Fisher, V. A., Drong, A., Zhang, Y., Feitosa, M. F., . . . Fox, C. S. (2017). Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. NATURE GENETICS, 49(1), 125-130. doi:10.1038/ng.3738

    DOI: 10.1038/ng.3738

    2016

    Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome (Journal article)

    Turner, R. M., Yin, P., Hanson, A., FitzGerald, R., Morris, A. P., Stables, R. H., . . . Pirmohamed, M. (2017). Investigating the prevalence, predictors, and prognosis of suboptimal statin use early after a non-ST elevation acute coronary syndrome. JOURNAL OF CLINICAL LIPIDOLOGY, 11(1), 204-214. doi:10.1016/j.jacl.2016.12.007

    DOI: 10.1016/j.jacl.2016.12.007

    A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits (Journal article)

    Asimit, J. L., Payne, F., Morris, A. P., Cordell, H. J., & Barroso, I. (2017). A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits. EUROPEAN JOURNAL OF HUMAN GENETICS, 25(3), 341-349. doi:10.1038/ejhg.2016.171

    DOI: 10.1038/ejhg.2016.171

    SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes (Journal article)

    Syed, H., Jorgensen, A. L., & Morris, A. P. (2016). SurvivalGWAS_Power: a user friendly tool for power calculations in pharmacogenetic studies with "time to event" outcomes. BMC BIOINFORMATICS, 17. doi:10.1186/s12859-016-1407-9

    DOI: 10.1186/s12859-016-1407-9

    A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape (Journal article)

    Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., . . . Loos, R. J. F. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. NATURE COMMUNICATIONS, 7. doi:10.1038/ncomms13357

    DOI: 10.1038/ncomms13357

    SNP-Treatment Interactions of Cardiovascular Medications and Risk of Acute Coronary Syndrome Recurrence (Conference Paper)

    Yin, P., Jorgensen, A., Morris, A., Turner, R., Fitzgerald, R., Stables, R., . . . Pirmohamed, M. (2016). SNP-Treatment Interactions of Cardiovascular Medications and Risk of Acute Coronary Syndrome Recurrence. In GENETIC EPIDEMIOLOGY Vol. 40 (pp. 672). Retrieved from http://gateway.webofknowledge.com/

    Genome-wide associations for birth weight and correlations with adult disease (Journal article)

    Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., . . . Consortium, E. G. G. (2016). Genome-wide associations for birth weight and correlations with adult disease. NATURE, 538(7624), 248-+. doi:10.1038/nature19806

    DOI: 10.1038/nature19806

    No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis (Journal article)

    Loley, C., Alver, M., Assimes, T. L., Bjonnes, A., Goel, A., Gustafsson, S., . . . Koenig, I. R. (2016). No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. SCIENTIFIC REPORTS, 6. doi:10.1038/srep35278

    DOI: 10.1038/srep35278

    The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (Journal article)

    Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., . . . Consor, W. T. C. C. (2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. NATURE GENETICS, 48(10), 1171-1184. doi:10.1038/ng.3667

    DOI: 10.1038/ng.3667

    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension (Journal article)

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., . . . Consortium, C. H. D. E. (2016). Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. NATURE GENETICS, 48(10), 1151-1161. doi:10.1038/ng.3654

    DOI: 10.1038/ng.3654

    Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity (Journal article)

    Mahajan, A., Rodan, A. R., Le, T. H., Gaulton, K. J., Haessler, J., Stilp, A. M., . . . Consortium, S. U. M. M. I. T. (2016). Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. AMERICAN JOURNAL OF HUMAN GENETICS, 99(3), 636-646. doi:10.1016/j.ajhg.2016.07.012

    DOI: 10.1016/j.ajhg.2016.07.012

    Cystatin C and Cardiovascular Disease A Mendelian Randomization Study (Journal article)

    van der Laan, S. W., Fall, T., Soumare, A., Teumer, A., Sedaghat, S., Baumert, J., . . . Asselbergs, F. W. (2016). Cystatin C and Cardiovascular Disease A Mendelian Randomization Study. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 68(9), 934-945. doi:10.1016/j.jacc.2016.05.092

    DOI: 10.1016/j.jacc.2016.05.092

    Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility (Journal article)

    Cook, J. P., & Morris, A. P. (2016). Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. EUROPEAN JOURNAL OF HUMAN GENETICS, 24(8), 1175-1180. doi:10.1038/ejhg.2016.17

    DOI: 10.1038/ejhg.2016.17

    Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci (Journal article)

    Walford, G. A., Gustafsson, S., Rybin, D., Stancakova, A., Chen, H., Liu, C. -T., . . . Florez, J. C. (2016). Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. DIABETES, 65(10), 3200-3211. doi:10.2337/db16-0199

    DOI: 10.2337/db16-0199

    The genetic architecture of type 2 diabetes (Journal article)

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., . . . McCarthy, M. I. (2016). The genetic architecture of type 2 diabetes. NATURE, 536(7614), 41-+. doi:10.1038/nature18642

    DOI: 10.1038/nature18642

    Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin (Journal article)

    Liu, C. -T., Raghavan, S., Maruthur, N., Kabagambe, E. K., Hong, J., Ng, M. C. Y., . . . Consortium, M. A. G. I. C. (2016). Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. AMERICAN JOURNAL OF HUMAN GENETICS, 99(1), 56-75. doi:10.1016/j.ajhg.2016.05.006

    DOI: 10.1016/j.ajhg.2016.05.006

    Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient (Journal article)

    Zondervan, K. T., Rahmioglu, N., Morris, A. P., Nyholt, D. R., Montgomery, G. W., Becker, C. M., & Missmer, S. A. (2016). Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient. SEMINARS IN REPRODUCTIVE MEDICINE, 34(4), 242-254. doi:10.1055/s-0036-1585408

    DOI: 10.1055/s-0036-1585408

    A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (Journal article)

    Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., . . . Consortium, C. A. R. D. I. O. G. R. A. M. E. (2016). A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. SCIENCE TRANSLATIONAL MEDICINE, 8(341). doi:10.1126/scitranslmed.aad3744

    DOI: 10.1126/scitranslmed.aad3744

    Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies (Journal article)

    Syed, H., Jorgensen, A. L., & Morris, A. P. (2016). Evaluation of methodology for the analysis of 'time-to-event' data in pharmacogenomic genome-wide association studies. PHARMACOGENOMICS, 17(8), 907-915. doi:10.2217/pgs.16.19

    DOI: 10.2217/pgs.16.19

    Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues (Journal article)

    Pervjakova, N., Kasela, S., Morris, A. P., Kals, M., Metspalu, A., Lindgren, C. M., . . . Magi, R. (2016). Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues. EPIGENOMICS, 8(6), 789-799. doi:10.2217/epi.16.8

    DOI: 10.2217/epi.16.8

    Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study (Journal article)

    Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., . . . Co, I. W. G. C. H. A. R. G. E. (2016). Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLOS MEDICINE, 13(6). doi:10.1371/journal.pmed.1001976

    DOI: 10.1371/journal.pmed.1001976

    Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight (Journal article)

    Tyrrell, J., Richmond, R. C., Palmer, T. M., Feenstra, B., Rangarajan, J., Metrustry, S., . . . Consortium, E. G. G. (2016). Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 315(11), 1129-1140. doi:10.1001/jama.2016.1975

    DOI: 10.1001/jama.2016.1975

    Leveraging Population-Based Cohorts to Understand the Genetic Aetiology of Benign Gynaecological Disorders and Their Overlap: The UK Biobank. (Conference Paper)

    Ferreira, T., Rahmioglu, N., Uimari, O., Becker, C. M., Morris, A. P., & Zondervan, K. T. (2016). Leveraging Population-Based Cohorts to Understand the Genetic Aetiology of Benign Gynaecological Disorders and Their Overlap: The UK Biobank.. In REPRODUCTIVE SCIENCES Vol. 23 (pp. 84A-85A). Retrieved from http://gateway.webofknowledge.com/

    Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms (Journal article)

    Horikoshi, M., Pasquali, L., Wiltshire, S., Huyghe, J. R., Mahajan, A., Asimit, J. L., . . . Consortium, T. -G. (2016). Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. HUMAN MOLECULAR GENETICS, 25(10), 2070-2081. doi:10.1093/hmg/ddw048

    DOI: 10.1093/hmg/ddw048

    Trans-ethnic study design approaches for fine-mapping (Journal article)

    Asimit, J. L., Hatzikotoulas, K., McCarthy, M., Morris, A. P., & Zeggini, E. (2016). Trans-ethnic study design approaches for fine-mapping. EUROPEAN JOURNAL OF HUMAN GENETICS, 24(9), 1330-1336. doi:10.1038/ejhg.2016.1

    DOI: 10.1038/ejhg.2016.1

    Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (Journal article)

    Knowles, J. W., Xie, W., Zhang, Z., Chennamsetty, I., Assimes, T. L., Paananen, J., . . . Quertermous, T. (2016). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. Journal of Clinical Investigation, 126(1), 403. doi:10.1172/jci85921

    DOI: 10.1172/jci85921

    A Genome-Wide Two-Component Mixture Model Expectation-Maximisation Algorithm for Time to Event Data (Conference Paper)

    Francis, B., Yin, P., Cook, J. P., Jorgensen, A. L., Hutton, J., & Morris, A. P. (2016). A Genome-Wide Two-Component Mixture Model Expectation-Maximisation Algorithm for Time to Event Data. In HUMAN HEREDITY Vol. 81 (pp. 212-213). Retrieved from http://gateway.webofknowledge.com/

    Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels (Journal article)

    Kilpelainen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., . . . Loos, R. J. F. (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. NATURE COMMUNICATIONS, 7. doi:10.1038/ncomms10494

    DOI: 10.1038/ncomms10494

    Investigating Fine-Scale Population Structure in UK BioBank (Conference Paper)

    Cook, J. P., & Morris, A. P. (2016). Investigating Fine-Scale Population Structure in UK BioBank. In HUMAN HEREDITY Vol. 81 (pp. 225). Retrieved from http://gateway.webofknowledge.com/

    Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs (Journal article)

    Below, J. E., Parra, E. J., Gamazon, E. R., Torres, J., Krithika, S., Candille, S., . . . Valladares-Salgado, A. (2016). Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. SCIENTIFIC REPORTS, 6. doi:10.1038/srep19429

    DOI: 10.1038/srep19429

    Multi-Phenotype Genome-Wide Meta-Analysis of Lipid Levels and BMI in 64,736 Europeans Suggests Shared Genetic Architecture (Conference Paper)

    Kaakinen, M., Lagou, V., Magie, R., Fischer, K., Morris, A. P., Prokopenko, I., & Consortium, E. N. G. A. G. E. (2016). Multi-Phenotype Genome-Wide Meta-Analysis of Lipid Levels and BMI in 64,736 Europeans Suggests Shared Genetic Architecture. In HUMAN HEREDITY Vol. 81 (pp. 213). Retrieved from http://gateway.webofknowledge.com/

    New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (Journal article)

    Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., . . . Loos, R. J. F. (2016). New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. NATURE COMMUNICATIONS, 7. doi:10.1038/ncomms10495

    DOI: 10.1038/ncomms10495

    SurvivalGWAS_RV: Software to Test Rare Variant Association with "Time-to-Event" Outcomes (Conference Paper)

    Syed, H., Jorgensen, A. L., & Morris, A. P. (2016). SurvivalGWAS_RV: Software to Test Rare Variant Association with "Time-to-Event" Outcomes. In HUMAN HEREDITY Vol. 81 (pp. 230). Retrieved from http://gateway.webofknowledge.com/

    2015

    Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15 (Journal article)

    Ek, W. E., Hedman, A. K., Enroth, S., Morris, A. P., Lindgren, C. M., Mahajan, A., . . . Johansson, A. (2016). Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15. HUMAN MOLECULAR GENETICS, 25(4), 817-827. doi:10.1093/hmg/ddv511

    DOI: 10.1093/hmg/ddv511

    A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits (Journal article)

    Asimit, J. L., Panoutsopoulou, K., Wheeler, E., Berndt, S. I., Cordell, H. J., Morris, A. P., . . . Consortium, A. (2015). A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits. GENETIC EPIDEMIOLOGY, 39(8), 624-634. doi:10.1002/gepi.21919

    DOI: 10.1002/gepi.21919

    Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci (Journal article)

    Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Maegi, R., Reschen, M. E., . . . Meta-A, D. G. R. (2015). Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. NATURE GENETICS, 47(12), 1415-+. doi:10.1038/ng.3437

    DOI: 10.1038/ng.3437

    Evaluation of methodology for the analysis of "time-toevent" data in pharmacogenetic studies (Conference Paper)

    Syed, H., Jorgensen, A., & Morris, A. P. (2015). Evaluation of methodology for the analysis of "time-toevent" data in pharmacogenetic studies. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 584). Retrieved from http://gateway.webofknowledge.com/

    Large-scale exomechip association analysis identifies novel type 2 diabetes susceptibility loci and highlights candidate effector genes (Conference Paper)

    Morris, A. P. (2015). Large-scale exomechip association analysis identifies novel type 2 diabetes susceptibility loci and highlights candidate effector genes. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 570). Retrieved from http://gateway.webofknowledge.com/

    MARV: Anovel method and software tool for genome-wide multi-phenotype analysis of rare variants (Conference Paper)

    Kaakinen, M., Magi, R., Fischer, K., Jarvelin, M. -R., Morris, A. P., & Prokopenko, I. (2015). MARV: Anovel method and software tool for genome-wide multi-phenotype analysis of rare variants. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 560). Retrieved from http://gateway.webofknowledge.com/

    Methodology for the analysis of multi-ethnic genome-wide association studies (Conference Paper)

    Cook, J. P., & Morris, A. P. (2015). Methodology for the analysis of multi-ethnic genome-wide association studies. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 540-541). Retrieved from http://gateway.webofknowledge.com/

    Pharmacogenetics of Acute Coronary Syndrome (Conference Paper)

    Yin, P., Jorgensen, A., Morris, A. P., Turner, R., Fitzgerald, R., Stables, R., . . . Pirmohamed, M. (2015). Pharmacogenetics of Acute Coronary Syndrome. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 596). Retrieved from http://gateway.webofknowledge.com/

    Shared polygenic effects of FEV1 in the first genetic study in UK Biobank (Conference Paper)

    Allen, R. J., Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., . . . Consortium, U. K. B. (2015). Shared polygenic effects of FEV1 in the first genetic study in UK Biobank. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 529-530). Retrieved from http://gateway.webofknowledge.com/

    Trans-ethnic meta-analysis reveals novel loci and effector genes for kidney function in diverse populations (Conference Paper)

    Mahajan, A., Haessler, J., Okada, Y., Stilp, A., Whitfield, J., Laurie, C., . . . Morris, A. P. (2015). Trans-ethnic meta-analysis reveals novel loci and effector genes for kidney function in diverse populations. In GENETIC EPIDEMIOLOGY Vol. 39 (pp. 567). Retrieved from http://gateway.webofknowledge.com/

    Shared genetics underlying epidemiological association between endometriosis and ovarian cancer (Journal article)

    Lu, Y., Cuellar-Partida, G., Painter, J. N., Nyholt, D. R., Morris, A. P., Fasching, P. A., . . . IEC. (2015). Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. HUMAN MOLECULAR GENETICS, 24(20), 5955-5964. doi:10.1093/hmg/ddv306

    DOI: 10.1093/hmg/ddv306

    A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (Journal article)

    Nikpay, M., Goel, A., Won, H. -H., Hall, L. M., Willenborg, C., Kanoni, S., . . . Consortium, C. (2015). A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. NATURE GENETICS, 47(10), 1121-+. doi:10.1038/ng.3396

    DOI: 10.1038/ng.3396

    Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank (Journal article)

    Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., . . . Consortium, O. (2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. LANCET RESPIRATORY MEDICINE, 3(10), 769-781. doi:10.1016/S2213-2600(15)00283-0

    DOI: 10.1016/S2213-2600(15)00283-0

    Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations (Journal article)

    Liu, J. Z., van Sommeren, S., Huang, H., Ng, S. C., Alberts, R., Takahashi, A., . . . Consortium, I. I. B. D. G. (2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. NATURE GENETICS, 47(9), 979-+. doi:10.1038/ng.3359

    DOI: 10.1038/ng.3359

    Genome-wide association study imputed to 1000 Genomes Project reference panels reveals 17 novel associations with type 2 diabetes (Conference Paper)

    Maegi, R., Scott, R. A., Morris, A. P., Marullo, L., Galton, K., Boehnke, M., . . . Consortium, D. I. -A. G. R. A. M. (2015). Genome-wide association study imputed to 1000 Genomes Project reference panels reveals 17 novel associations with type 2 diabetes. In DIABETOLOGIA Vol. 58 (pp. S90). Retrieved from http://gateway.webofknowledge.com/

    Genome-wide multi-phenotype rare variant association analysis detects effect of ZNF259 on fasting insulin and triglyceride levels (Conference Paper)

    Kaakinen, M., Maegi, R., Fischer, K., Jaervelin, M. -R., Morris, A. P., & Prokopenko, I. (2015). Genome-wide multi-phenotype rare variant association analysis detects effect of ZNF259 on fasting insulin and triglyceride levels. In DIABETOLOGIA Vol. 58 (pp. S143). Retrieved from http://gateway.webofknowledge.com/

    High-density imputation and trans-ethnic association analysis reveals a novel locus for type 2 diabetes susceptibility (Conference Paper)

    Morris, A. P. (2015). High-density imputation and trans-ethnic association analysis reveals a novel locus for type 2 diabetes susceptibility. In DIABETOLOGIA Vol. 58 (pp. S89-S90). Retrieved from http://gateway.webofknowledge.com/

    Directional dominance on stature and cognition in diverse human populations (Journal article)

    Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., . . . Project, B. J. (2015). Directional dominance on stature and cognition in diverse human populations. NATURE, 523(7561), 459-U176. doi:10.1038/nature14618

    DOI: 10.1038/nature14618

    Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation (Journal article)

    Horikoshi, M., Maegi, R., van de Bunt, M., Surakka, I., Sarin, A. -P., Mahajan, A., . . . Consortium, E. (2015). Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PLOS GENETICS, 11(7). doi:10.1371/journal.pgen.1005230

    DOI: 10.1371/journal.pgen.1005230

    Genetic burden associated with varying degrees of disease severity in endometriosis. (Journal article)

    Sapkota, Y., Attia, J., Gordon, S. D., Henders, A. K., Holliday, E. G., Rahmioglu, N., . . . Nyholt, D. R. (2015). Genetic burden associated with varying degrees of disease severity in endometriosis.. Molecular human reproduction, 21(7), 594-602.

    Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample (Journal article)

    Ng, E., Salihovic, S., Lind, P. M., Mahajan, A., Syvanen, A. -C., Axelsson, T., . . . Lind, L. (2015). Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. ENVIRONMENTAL RESEARCH, 140, 95-101. doi:10.1016/j.envres.2015.03.022

    DOI: 10.1016/j.envres.2015.03.022

    The impact of low-frequency and rare variants on lipid levels (Journal article)

    Surakka, I., Horikoshi, M., Magi, R., Sarin, A. -P., Mahajan, A., Lagou, V., . . . Consortium, E. N. G. A. G. E. (2015). The impact of low-frequency and rare variants on lipid levels. NATURE GENETICS, 47(6), 589-597. doi:10.1038/ng.3300

    DOI: 10.1038/ng.3300

    GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb (Journal article)

    den Hoed, M., Strawbridge, R. J., Almgren, P., Gustafsson, S., Axelsson, T., Engstrom, G., . . . Lind, L. (2015). GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb. ATHEROSCLEROSIS, 239(2), 304-310. doi:10.1016/j.atherosclerosis.2015.01.032

    DOI: 10.1016/j.atherosclerosis.2015.01.032

    Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (Journal article)

    Knowles, J. W., Xie, W., Zhang, Z., Chennemsetty, I., Assimes, T. L., Paananen, J., . . . Pacific, S. A. P. P. H. I. R. E. S. A. (2015). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. JOURNAL OF CLINICAL INVESTIGATION, 125(4), 1739-1751. doi:10.1172/JCI74592

    DOI: 10.1172/JCI74592

    Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (Journal article)

    Knowles, J. W., Xie, W., Zhang, Z., Chennemsetty, I., Assimes, T. L., Paananen, J., . . . Quertermous, T. (2015). Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. Journal of Clinical Investigation, 125(4), 1739-1751. doi:10.1172/jci74692

    DOI: 10.1172/jci74692

    Genetic studies of body mass index yield new insights for obesity biology (Journal article)

    Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., . . . Consortium, I. E. (2015). Genetic studies of body mass index yield new insights for obesity biology. NATURE, 518(7538), 197-U401. doi:10.1038/nature14177

    DOI: 10.1038/nature14177

    New genetic loci link adipose and insulin biology to body fat distribution (Journal article)

    Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Lockes, A. E., Maegi, R., . . . Consortium, R. (2015). New genetic loci link adipose and insulin biology to body fat distribution. NATURE, 518(7538), 187-U378. doi:10.1038/nature14132

    DOI: 10.1038/nature14132

    Smoking is associated with mosaic loss of chromosome Y (Journal article)

    Dumanski, J. P., Rasi, C., Lonn, M., Davies, H., Ingelsson, M., Giedraitis, V., . . . Forsberg, L. A. (2015). Smoking is associated with mosaic loss of chromosome Y. SCIENCE, 347(6217), 81-83. doi:10.1126/science.1262092

    DOI: 10.1126/science.1262092

    A Novel Method and Software Tool for Genome-Wide Multi-Phenotype Analysis of Rare Variants (Conference Paper)

    Kaakinen, M., Maegi, R., Fischer, K., Jarvelin, M. -R., Morris, A. P., & Prokopenko, I. (2015). A Novel Method and Software Tool for Genome-Wide Multi-Phenotype Analysis of Rare Variants. In HUMAN HEREDITY Vol. 79 (pp. 39). Retrieved from http://gateway.webofknowledge.com/

    Association between endometriosis and the interleukin 1A (IL1A) locus (Journal article)

    Sapkota, Y., Low, S. -K., Attia, J., Gordon, S. D., Henders, A. K., Holliday, E. G., . . . Nyholt, D. R. (2015). Association between endometriosis and the interleukin 1A (IL1A) locus. Human Reproduction, 30(1), 239-248. doi:10.1093/humrep/deu267

    DOI: 10.1093/humrep/deu267

    Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci (Journal article)

    van de Bunt, M., Cortes, A., Brown, M. A., Morris, A. P., McCarthy, M. I., & Consortium, I. G. A. S. (2015). Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci. PLOS GENETICS, 11(9). doi:10.1371/journal.pgen.1005535

    DOI: 10.1371/journal.pgen.1005535

    Fine Mapping of Type 2 Diabetes Susceptibility Loci (vol 14, 549, 2014) (Journal article)

    Morris, A. P. (2015). Fine Mapping of Type 2 Diabetes Susceptibility Loci (vol 14, 549, 2014). CURRENT DIABETES REPORTS, 15(1). doi:10.1007/s11892-014-0575-0

    DOI: 10.1007/s11892-014-0575-0

    Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus (Journal article)

    Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., . . . Consortium, G. T. (2015). Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. PLOS GENETICS, 11(1). doi:10.1371/journal.pgen.1004876

    DOI: 10.1371/journal.pgen.1004876

    Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (Journal article)

    Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., . . . BiLEVE, U. K. (2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. NATURE COMMUNICATIONS, 6. doi:10.1038/ncomms9658

    DOI: 10.1038/ncomms9658

    2014

    Trans-ethnic meta-analysis of white blood cell phenotypes (Journal article)

    Keller, M. F., Reiner, A. P., Okada, Y., van Rooij, F. J. A., Johnson, A. D., Chen, M. -H., . . . RIKEN, B. J. P. (2014). Trans-ethnic meta-analysis of white blood cell phenotypes. HUMAN MOLECULAR GENETICS, 23(25), 6944-6960. doi:10.1093/hmg/ddu401

    DOI: 10.1093/hmg/ddu401

    Associations of genetic variants in/near body mass index- associated genes with type 2 diabetes: a systematic meta-analysis (Journal article)

    Xi, B., Takeuchi, F., Meirhaeghe, A., Kato, N., Chambers, J. C., Morris, A., . . . Chandak, G. R. (2014). Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clinical Endocrinology, 81(5), 702-710.

    Defining the role of common variation in the genomic and biological architecture of adult human height (Journal article)

    Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., . . . Study, L. C. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. NATURE GENETICS, 46(11), 1173-1186. doi:10.1038/ng.3097

    DOI: 10.1038/ng.3097

    Fine Mapping of Type 2 Diabetes Susceptibility Loci (Journal article)

    Morris, A. P. (2014). Fine Mapping of Type 2 Diabetes Susceptibility Loci. CURRENT DIABETES REPORTS, 14(11). doi:10.1007/s11892-014-0549-2

    DOI: 10.1007/s11892-014-0549-2

    Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci (Journal article)

    Rahmioglu, N., Macgregor, S., Drong, A. W., Hedman, A. K., Harris, H. R., Randall, J. C., . . . Consortium, G. I. A. N. T. (2015). Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. HUMAN MOLECULAR GENETICS, 24(4), 1185-1199. doi:10.1093/hmg/ddu516

    DOI: 10.1093/hmg/ddu516

    Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. (Journal article)

    Coffee and Caffeine Genetics Consortium., Cornelis, M. C., Byrne, E. M., Esko, T., Nalls, M. A., Ganna, A., . . . Chasman, D. I. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.. Molecular psychiatry, 20(5), 647-656. doi:10.1038/mp.2014.107

    DOI: 10.1038/mp.2014.107

    Dissecting the genetic architecture of loci with established effects on multiple cardiometabolic phenotypes and type 2 diabetes (Journal article)

    Marullo, L., Kilpelainen, T. O., Cornes, B. K., Dupuis, J., Scapoli, C., Loos, R. J. F., . . . Grp, X. -P. (2014). Dissecting the genetic architecture of loci with established effects on multiple cardiometabolic phenotypes and type 2 diabetes. DIABETOLOGIA, 57, S149. Retrieved from http://gateway.webofknowledge.com/

    FOXA2 bound sites are enriched for type 2 diabetes risk variants (Journal article)

    Gaulton, K. J., Morris, A. P., McCarthy, M. I., & Consortium, D. I. A. G. R. A. M. (2014). FOXA2 bound sites are enriched for type 2 diabetes risk variants. DIABETOLOGIA, 57, S66. Retrieved from http://gateway.webofknowledge.com/

    Fine-mapping type 2 diabetes susceptibility loci with high-density imputation (Journal article)

    Morris, A. P., Teslovich, T. M., Ferreira, T., Mahajan, A., Lee, Y., Rayner, N. W., . . . Consortium, D. I. A. G. R. A. M. (2014). Fine-mapping type 2 diabetes susceptibility loci with high-density imputation. DIABETOLOGIA, 57, S50-S51. Retrieved from http://gateway.webofknowledge.com/

    Meta-analysis of birth weight genome-wide association studies identifies two novel loci extending links between early growth and adult metabolic diseases (Journal article)

    Horikoshi, M., Kooijman, M. N., Bradield, J. P., Strachan, D., Tejedor, N. V., Kreiner-Moller, E., . . . Consortium, E. G. G. (2014). Meta-analysis of birth weight genome-wide association studies identifies two novel loci extending links between early growth and adult metabolic diseases. DIABETOLOGIA, 57, S51. Retrieved from http://gateway.webofknowledge.com/

    Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits (Journal article)

    Moutsianas, L., & Morris, A. P. (2014). Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits. BRIEFINGS IN FUNCTIONAL GENOMICS, 13(5), 362-370. doi:10.1093/bfgp/elu012

    DOI: 10.1093/bfgp/elu012

    Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample (Journal article)

    Lind, L., Penell, J., Syvänen, A. -C., Axelsson, T., Ingelsson, E., Morris, A. P., . . . Lind, P. M. (2014). Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. Environmental Research, 133, 135-140. doi:10.1016/j.envres.2014.05.017

    DOI: 10.1016/j.envres.2014.05.017

    Pleiotropic genes for metabolic syndrome and inflammation. (Journal article)

    Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Kilpeläinen, T. O., . . . Borecki, I. B. (2014). Pleiotropic genes for metabolic syndrome and inflammation.. Molecular Genetics and Metabolism, 112(4), 317-338.

    Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin. (Journal article)

    Bolton, J. L., Hayward, C., Direk, N., Lewis, J. G., Hammond, G. L., Hill, L. A., . . . Walker, B. R. (2014). Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin.. PLoS Genetics, 10(7), e1004474.

    Genome-wide association analysis identifies six new loci associated with forced vital capacity (Journal article)

    Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., . . . London, S. J. (2014). Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics, 46(7), 669-677. doi:10.1038/ng.3011

    DOI: 10.1038/ng.3011

    Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. (Journal article)

    Forsberg, L. A., Rasi, C., Malmqvist, N., Davies, H., Pasupulati, S., Pakalapati, G., . . . Dumanski, J. P. (2014). Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.. Nature Genetics, 46(6), 624-628.

    Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study. (Journal article)

    Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., . . . Wareham, N. J. (2014). Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.. PLoS medicine, 11(5), e1001647.

    Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort (Journal article)

    Becker, J., Czamara, D., Scerri, T. S., Ramus, F., Csepe, V., Talcott, J. B., . . . Schumacher, J. (2014). Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort. EUROPEAN JOURNAL OF HUMAN GENETICS, 22(5), 675-680. doi:10.1038/ejhg.2013.199

    DOI: 10.1038/ejhg.2013.199

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes (Journal article)

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., . . . Consortium, T. -G. (2014). Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. NATURE GENETICS, 46(4), 357-+. doi:10.1038/ng.2915

    DOI: 10.1038/ng.2915

    Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (Journal article)

    Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., . . . Exploration, T. 2. D. G. (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. NATURE GENETICS, 46(3), 234-+. doi:10.1038/ng.2897

    DOI: 10.1038/ng.2897

    An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins (Journal article)

    Yuan, W., Xia, Y., Bell, C. G., Yet, I., Ferreira, T., Ward, K. J., . . . Spector, T. D. (2014). An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins. NATURE COMMUNICATIONS, 5. doi:10.1038/ncomms6719

    DOI: 10.1038/ncomms6719

    Fine Mapping Type 2 Diabetes Susceptibility Loci (Journal article)

    Morris, A. P. (2014). Fine Mapping Type 2 Diabetes Susceptibility Loci. Unknown Journal, 14-28. doi:10.1159/000362464

    DOI: 10.1159/000362464

    Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study. (Journal article)

    Penell, J., Lind, L., Fall, T., Syvänen, A. -C., Axelsson, T., Lundmark, P., . . . Lind, P. M. (2014). Genetic variation in the CYP2B6 gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study.. Environmental health : a global access science source, 13(1), 34.

    Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function (Journal article)

    Tang, W., Kowgier, M., Loth, D. W., Artigas, M. S., Joubert, B. R., Hodge, E., . . . Cassano, P. A. (2014). Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function. PLOS ONE, 9(7). doi:10.1371/journal.pone.0100776

    DOI: 10.1371/journal.pone.0100776

    2000

    Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets (Journal article)

    Rahmioglu, N., Nyholt, D. R., Morris, A. P., Missmer, S. A., Montgomery, G. W., & Zondervan, K. T. (2014). Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets. HUMAN REPRODUCTION UPDATE, 20(5), 702-716. doi:10.1093/humupd/dmu015

    DOI: 10.1093/humupd/dmu015

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (Journal article)

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., . . . Consortium, M. A. G. I. C. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS GENETICS, 11(10). doi:10.1371/journal.pgen.1005378

    DOI: 10.1371/journal.pgen.1005378