Sanyu Research Unit

Projects

News

COPE Study - £1.8m for major new study into bleeding after childbirth

INFORM study

Researchers from the University’s Institute of Translational Medicine (ITM) with colleagues from Gynuity Health Care in New York and the Government Medial College, Nagpur, India, have published a major study of two different types of labour induction methods in The Lancet.

Principal objective: Between 62 000 and 77 000 women die annually from pre-eclampsia and eclampsia. Prompt delivery, preferably by the vaginal route, is vital for good maternal and neonatal outcomes. Two low-cost interventions—low-dose oral misoprostol tablets and transcervical Foley catheterisation—are already used in low-resource settings. We aimed to compare the relative risks and benefits of these interventions.

Post-Partum Haemorrhage (PPH) Butterfly

A development study funded by the NiHR Invention for Innovation (i4i) programme. Sponsored by University of Liverpool

Principal Objective: To recruitup to 10 healthy volunteers (who have just given birth) in order to test the usability/suitability of a novel medical device. Developed by the Chief Investigator (Weeks) this novel medical device may significantly contribute towards an acceptable solution for management of PPH.

Visit the PPH Butterfly website.

Effectiveness of antibiotic prophylaxis during surgical evacuation of the uterus for miscarriage management in low income countries: a multinational, randomised, double-blind placebo-controlled trial (AIMS study)

Funded by the MRC, Sponsored by the University of Birmingham, this multi-centre study is run across sites in low resources settings including Mbale, Uganda, through the Sanyu Africa Research Institute (SAfRI)

Principal Objective: To test the hypothesis that in women having miscarriage surgery, pre-surgery prophylactic antibiotics (oral doxycycline 400mg and oral metronidazole 400mg) reduces the risk of pelvic infection within 14 days of surgery.

 Babygel study Funded by the MRC Sponsored by the University of Liverpool run through SAfRI, Mbale, Uganda.

Pilot study of a cluster randomised trial of the provision of alcohol hand gel to postpartum mothers to prevent neonatal infective morbidity in the home. 

 FIGO/Wellbeing for Woman Fellowship A three year funded project to support research capacity and capability building. The Fellowship is supporting Professor Julius Wandabwa, Head of Obstetrics and Gynaecology at Busitema University, Uganda to undertake a period of research training at the University of Liverpool and other local partner organisations.
 PPH Definitions A study being undertaken by Professor Andrew and Dr. Robbie Kerr. Coordinating an international group of experts, as part of a WHO/Brighton Colloboration, to develop a consensus on the definition of postpartum haemorrhage. The project aims to standardize the definition of post-partum haemorrhage for monitoring the safety of immunisation in pregnancy.
Misoprostol or Oxytocin for Labour Induction (MOLI) Study

The University of Liverpool in the UK will work with Gynuity Health Projects (www.gynuity.org) in New York, USA and the Government Medical College in Nagpur to run the MOLI study in three sites in Nagpur, India. The study seeks to explore whether augmentation using oral misoprostol is superior to the standard protocol of intravenous oxytocin in Indian women who have undergone cervical preparation with oral misoprostol as part of labour induction for hypertensive disease. The primary outcome is the rate of caesarean birth, but the study will also consider satisfaction and cost. The study seeks to recruit 1000 women across the three sites.

PhD Students

 

Dr. Achier Akol

“Retrospective Cohort Study of Liverpool women to Explore factors and outcomes associated with various forms of retained placenta from 2009 to 2014”

“A prospective study of the diagnostic role of ultrasound amongst women with retained placentas“

 

Dr. Abiola Aiyenigba

“The Management of Psychological Morbidities associated with Infertility within African populations.

This includes the development of a CBT based counselling intervention called FELICIA (FErtility LIfe Counselling In Africa.)”