Clinical Trials Research Centre (Clinical Trials Unit)


Clinical Trial of Investigational Medicinal Products (CTIMP)

Study Topic Population Design Website
TORPEDO-CF Pseudomonas Eradication Paediatric - Cystic Fibrosis RCT Visit Website
SCIPI Insulin delivered as continuous subcutaneous infusion compared to multiple daily injections Paediatric - Diabetes RCT Visit Website
SYCAMORE Adalumimab in paediatric uveitis secondary to juvenile idiopathic arthritis Paediatric - Arthritis RCT Visit Website
MYPAN Mycophenolate mofetil versus cyclophosphamide for  polyarteritis nodosa Paediatric - Polyarteritis RCT  
HUMOX Humidified oxygen versus standard oxygen therapy Paediatric - Asthma Pilot  
SANAD-II Standard and New Anti-epileptic Drugs Adult/Paediatric - Epilepsy RCT Visit Website
TAILOR TelmisArtan and InsuLin Resistance in HIV Adults - HIV RCT Visit Website
ECLIPSE Emergency treatment with LevetIracetam or Phenytoin in Status Epilepticus Paediatric RCT  
OVERT Botulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A randomised controlled trial Paediatric RCT  
PROTEKT Phase IIa, Randomised, Controlled, OpenLabel Trial of Rosuvastatin for the Prevention of AminoglycosideInduced Kidney Toxicity in Children with Cystic Fibrosis Paediatric RCT  
TREAT Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial Paediatric RCT  
APTITUDE APTITUDE A phase II trial of Tocilizumab in anti-TNF refractory patients with JIA associated uveitis Paediatric RCT  
DEX ENCEPH COrticosteroids in Herpes SImplex Virus Encephalitis Adult/Paediatric    

Non -CTIMP Clinical Trials

Study Topic Population Design Website
SAFE Seizure first aid training for epilepsy (pilot) Epilepsy Pilot  
EDIBLE Epilepsy - Strategies to improve diagnosis, prevention and treatment Paediatric - Epilepsy    
ISDR Screening for diabetic retinopathy  Adults - Diabetes RCT Pending
DENTALRECUR Primary care service to reduce the re-occurrence of childhood dental caries Adult / Paediatric - Dental RCT  
ENCEPH Encephalitis  -implementation of guidelines Adult / Paediatric - Encephalitis Cohort and Cluster RCT Visit Website
SLUMBRS Sleep position in cleft babies (SLUMBERS) feasibility Paediatric RCT  
ACORN Improving oral health in cleft lip and/or palate: A health promotion Paediatric Health Promotion  
REACT An online randomised controlled trial to evaluate the clinical and cost effectiveness of the Relatives Education And Coping Toolkit (REACT) Adult RCT  

Surgical Clinical Trials  (Including devices)

Study Topic Population Design Website
TOPS-CP Timing of Primary Surgery for Cleft Palate Paediatric - Cleft Palate RCT Visit Website
BASICS Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts Paediatric - Hydrocephalus RCT Pending
NERVES Transforaminal epidural steroid injection to surgical microdiscectomy for the treatment of acute lumbar radicular pain Adult RCT  

Devices Clinical Trials

Study Topic Population Design Website
VISION Visual rehabilitation versus standard care on functional outcomes for stroke survivors with homonymous hemianopia Adult - Stroke RCT Visit Website
PREVAIL Preventing Infection using Antibiotic Impregnated Long Lines Paediatric Open two-arm, multi-centre RCT  

Research Methodology

Study Topic Population Design Website
EPIC Optimise methods for involving patient and public representatives in clinical trials:  a systematic investigation of a cohort of Health Technology Assessment funded clinical trials PPI Cohort Visit Website

Other Research Designs

Study Topic Population Design Website
DINOSAUR Duration of INtravenous antibiOtic therapy for Septic Arthritis or acUte osteomyelitis  Paediatric - Arthritis Service Evaluation Visit Website
JSLE Clinical characteristics and immunopathology of juvenile Systemic Lupus Erythermatosisonset  Paediatric - Lupus Repository  
MOMENT Management of Otitis Media with Effusion in Children with Cleft Palate - mOMEnt Paediatric - Cleft Palate Qualitative  
PRACTICAL Procalcitonin, APTT waveform and 16S rDNA in the diagnosis of CaTheter-associated Infections in children with Cancer and Leukaemia Paediatric - Infection Oncology Cohort  
  ReaDySpeech for people with dysarthria after stroke: a feasibility study. ADD   Feasibility  
  Core outcome set for anal cancer studies ADD   Core Outcome Set  
  Neighbourhoods and Dementia ADD   Core Outcome Set  
  Prediction and prevention of adverse pregnancy outcomes in women with chronic vascular disease Pregnancy    
IVIS Impact of Visual Impairment after Stroke (IVIS) Vision    
ROAM Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial) Adult (16+) Open two-arm, multi-centre RCT  


Jo Gardner
Clinical Trials Research Centre
University of Liverpool

Telephone: 0151 282 4724
Facsimile: 0151 282 4721


Postal address:

Institute of Child Health
Alder Hey Children's Hospital
Eaton Road, Liverpool
L12 2AP