Portfolio
Clinical Trial of Investigational Medicinal Products (CTIMP)
| Study | Topic | Population | Design | Website |
| TORPEDO-CF | Pseudomonas Eradication | Paediatric - Cystic Fibrosis | RCT | Visit Website |
| SCIPI | Insulin delivered as continuous subcutaneous infusion compared to multiple daily injections | Paediatric - Diabetes | RCT | Visit Website |
| SYCAMORE | Adalumimab in paediatric uveitis secondary to juvenile idiopathic arthritis | Paediatric - Arthritis | RCT | Visit Website |
| MYPAN | Mycophenolate mofetil versus cyclophosphamide for polyarteritis nodosa | Paediatric - Polyarteritis | RCT | |
| HUMOX | Humidified oxygen versus standard oxygen therapy | Paediatric - Asthma | Pilot | |
| SANAD-II | Standard and New Anti-epileptic Drugs | Adult/Paediatric - Epilepsy | RCT | Visit Website |
| TAILOR | TelmisArtan and InsuLin Resistance in HIV | Adults - HIV | RCT | Visit Website |
| ECLIPSE | Emergency treatment with LevetIracetam or Phenytoin in Status Epilepticus | Paediatric | RCT | |
| OVERT | Botulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A randomised controlled trial | Paediatric | RCT | |
| PROTEKT | Phase IIa, Randomised, Controlled, OpenLabel Trial of Rosuvastatin for the Prevention of AminoglycosideInduced Kidney Toxicity in Children with Cystic Fibrosis | Paediatric | RCT | |
| TREAT | Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial | Paediatric | RCT | |
| APTITUDE | APTITUDE A phase II trial of Tocilizumab in anti-TNF refractory patients with JIA associated uveitis | Paediatric | RCT | |
| DEX ENCEPH | COrticosteroids in Herpes SImplex Virus Encephalitis | Adult/Paediatric |
Non -CTIMP Clinical Trials
| Study | Topic | Population | Design | Website |
| SAFE | Seizure first aid training for epilepsy (pilot) | Epilepsy | Pilot | |
| EDIBLE | Epilepsy - Strategies to improve diagnosis, prevention and treatment | Paediatric - Epilepsy | ||
| ISDR | Screening for diabetic retinopathy | Adults - Diabetes | RCT | Pending |
| DENTALRECUR | Primary care service to reduce the re-occurrence of childhood dental caries | Adult / Paediatric - Dental | RCT | |
| ENCEPH | Encephalitis -implementation of guidelines | Adult / Paediatric - Encephalitis | Cohort and Cluster RCT | Visit Website |
| SLUMBRS | Sleep position in cleft babies (SLUMBERS) feasibility | Paediatric | RCT | |
| ACORN | Improving oral health in cleft lip and/or palate: A health promotion | Paediatric | Health Promotion | |
| REACT | An online randomised controlled trial to evaluate the clinical and cost effectiveness of the Relatives Education And Coping Toolkit (REACT) | Adult | RCT |
Surgical Clinical Trials (Including devices)
| Study | Topic | Population | Design | Website |
| TOPS-CP | Timing of Primary Surgery for Cleft Palate | Paediatric - Cleft Palate | RCT | Visit Website |
| BASICS | Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts | Paediatric - Hydrocephalus | RCT | Pending |
| NERVES | Transforaminal epidural steroid injection to surgical microdiscectomy for the treatment of acute lumbar radicular pain | Adult | RCT |
Devices Clinical Trials
| Study | Topic | Population | Design | Website |
| VISION | Visual rehabilitation versus standard care on functional outcomes for stroke survivors with homonymous hemianopia | Adult - Stroke | RCT | Visit Website |
| PREVAIL | Preventing Infection using Antibiotic Impregnated Long Lines | Paediatric | Open two-arm, multi-centre RCT |
Research Methodology
| Study | Topic | Population | Design | Website |
| EPIC | Optimise methods for involving patient and public representatives in clinical trials: a systematic investigation of a cohort of Health Technology Assessment funded clinical trials | PPI | Cohort | Visit Website |
Other Research Designs
| Study | Topic | Population | Design | Website |
| DINOSAUR | Duration of INtravenous antibiOtic therapy for Septic Arthritis or acUte osteomyelitis | Paediatric - Arthritis | Service Evaluation | Visit Website |
| JSLE | Clinical characteristics and immunopathology of juvenile Systemic Lupus Erythermatosisonset | Paediatric - Lupus | Repository | |
| MOMENT | Management of Otitis Media with Effusion in Children with Cleft Palate - mOMEnt | Paediatric - Cleft Palate | Qualitative | |
| PRACTICAL | Procalcitonin, APTT waveform and 16S rDNA in the diagnosis of CaTheter-associated Infections in children with Cancer and Leukaemia | Paediatric - Infection Oncology | Cohort | |
| ReaDySpeech for people with dysarthria after stroke: a feasibility study. ADD | Feasibility | |||
| Core outcome set for anal cancer studies ADD | Core Outcome Set | |||
| Neighbourhoods and Dementia ADD | Core Outcome Set | |||
| Prediction and prevention of adverse pregnancy outcomes in women with chronic vascular disease | Pregnancy | |||
| IVIS | Impact of Visual Impairment after Stroke (IVIS) | Vision | ||
| ROAM | Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial) | Adult (16+) | Open two-arm, multi-centre RCT |
Contact:
Jo Gardner
Administrator
Clinical Trials Research Centre
University of Liverpool
Telephone: 0151 282 4724
Facsimile: 0151 282 4721
Email: jogard@liverpool.ac.uk
Postal address:
Institute of Child Health
Alder Hey Children's Hospital
Eaton Road, Liverpool
L12 2AP