Clinical Trials Research Centre (Clinical Trials Unit)

Essential Links

Clinical Trials Tool kit

DOH/MRC  tool with each step of the trial and links to relevant documents and regulations.

Clinical Trials Tool kit Routemap

Clinical Trials Units Clinical Trials Units (powerpoint file)
Clinical Studies Groups

National networks of expertise across all areas of healthcare. See contacts page.

Comprehensive Research Networks  (CLRN)

CLRN coordinate and facilitate the conduct of clinical research and provide a wide range of support to NHS research

New configuration
Consort

To improve the reporting of a randomized controlled trial (RCT), enabling readers to understand a trial's design, conduct, analysis and interpretation, and to assess the validity of its results

Consort Link
Core Outcome Measures for Clinical Trials COMET

The development and application of agreed standardised sets of outcomes, known as ‘core outcome sets’. These sets represent the minimum that should be measured and reported in all clinical trials of a specific condition, and are also suitable for use in clinical audit or research other than randomised trials.

COMET

Costing the research 

Guidelines on costing research for funding applications 

Funding Applications NETSCC NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) NETSCC manage the identifying, prioritising, funding, delivery, publication, and dissemination of high-quality research and lead other NIHR initiatives to meet the needs of the public, patients and the NHS.
Health Economics When is it required in a trial?
MHRA Good Clinical Practice Essential reading for Clinical Trials of Medicinal Products ISBN 9780117081079 publisher TSO
MRC Guide Complex Interventions MRC Guide Complex Interventions
North West Research Design Service 

Provide pre funding advice in the research design with access to specialised advisors in clinical trials, health economics, PPI, qualitative, statistics and other methods.

http://www.rds-nw.nihr.ac.uk/

Pilot and Feasibility Studies NETSCC definitions  
Protocol Development - Spirit Guidelines

What to include in a research protocol

SPIRIT-Checklist

Patient Public Involvement

PPI How to guide

Involve 

Research Design Service (Bursary available for PPI activities)