The Liverpool BRAIN (Brain Research Advanced Imaging Network)

Activities

Regular meetings

We meet informally once every two weeks to present neuroimaging data, review new relevant neuroimaging papers and discuss future research.

We welcome people to join us either in person or by Zoom (please see contact page). Our meetings are relaxed and interactive. We encourage collaboration!

We also meet monthly with the rest of the Liverpool Epilepsy Research Group (LERG), alternating meeting sites between the University of Liverpool and the Walton Centre.

  • Selected recent invited talks at research institutes and societies

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    • Keller, S. S. “Epilepsy and new developments in neuroimaging.” National Institute for Mental Health and Neurosciences (NIMHANS), Bangalore, India, July 2019.
    • Keller, S. S. “Neuroimaging in Epilepsy: diagnostics, mechanisms and prognostics.” Masaryk University, Brno, Czech Republic, December 2018.
    • Keller, S. S. "MRI in Epilepsy: clinical evaluation and new advances.”, Czech Academy of Sciences, Prague, Czech Republic, November 2018.
    • Keller, S. S. “Structural Neuroimaging in Epilepsy: Clinical Applications and New Advances.” Institute of Neuroscience, University of Newcastle, UK, October 2015.
    • Keller, S. S. “New MRI approaches in refractory epilepsy.” Medical University of South Carolina, USA, September 2015.
    • Keller, S. S. “New Advances in neuroimaging in epilepsy.” University Hospital for Neurology, Bern, Switzerland, September 2015.
    • Keller, S. S. “Prospective neuroimaging studies in newly diagnosed epilepsy.” The Epilepsy Society, Chalfont Hospital, UK, June 2014.
    • Keller, S. S. Seizure control after temporal lobe surgery: what can we learn from preoperative quantitative MRI? The Institute of Neurology, University College London, UK, June 2014.
  • Recent conference presentations and invited talks

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    2019

    American Epilepsy Society, Baltimore, USA. December 2019.

    • Bryant, L., McKinnon, E., Taylor, J., A., Bonilha, L., Jensen, J., Wieshmann, U., Adan, G., Biswas, S., Marson, A. G., Keller, S. S. Fiber ball white matter modelling in patients with focal epilepsy. Platform presentation.
    • Kreilkamp, B. A. K., McKavanah, A., Bryant, L., Alonazi, B., Das, K., Marson, A. G., Taylor, P., Keller, S. S. Altered diffusion connectome in patients with nonlesional newly diagnosed focal epilepsy.
    • McKavanah, A., Kreilkamp, B. A. K., Denby, C., Bracewell, M., Das, K., Marson, A. G., Taylor, P., Keller, S. S. Structural brain network changes in idiopathic generalized epilepsy analysed using network based statistics (NBS).
    • Chen, Y., Denby, C., Kreilkamp, B. A. K., Bracewell, M., Das, K., Fallon, N., Pegg, E., Mohanraj, R., Marson, A. G., Keller, S. S. Automated white matter tractography in genetic generalized epilepsy.
    • Leek, N., Neason, M., Ziso, B., Elkommos, S., Kreilkamp, B. A. K., Das, K., Marson, A. G., Keller, S. S. MRI volumetry reveals thalamic atrophy in patients with newly diagnosed focal epilepsy.
    • Adan, G., Isse, M., Weber, B., Keller, S. S. Volumetric analysis of the insular cortex in patients with refractory temporal lobe epilepsy: relation to postsurgical outcome.
    • Brownhill, D., Chen, Y., Kreilkamp, B. A. K., Denby, C., Bracewell, M., Das, K., Marson, T., Keller, S. S. Automatic subcortical segmentation and volume estimation of 2D T1-weighted MRI in epilepsy.
    • The ENIGMA Epilepsy working group. White matter microstructural alterations in 1249 patients with epilepsy and 1069 controls: findings from the ENIGMA Epilepsy working group. American Epilepsy Society (AES), Baltimore, USA.

    International League Against Epilepsy, Birmingham, UK. October 2019.

    • Keller, S. S. Invited talk: “Seizures as a network.”

    Organisation for Human Brain Mapping, Rome, Italy. June 2019.

    • Kreilkamp, B. A. K., Lisanti, L., Glenn, G. R., Wieshmann, U. C., Das, K., Marson, A. G., Keller, S. S. Comparison of manual and automated tractography methods in patients with refractory temporal lobe epilepsy. Organisation of Human Brain Mapping (OHBM), Rome, Italy.
    • Kreilkamp, B. A. K. Hackathon: “Automated cortical lesion detection using Python tool”.

    International Epilepsy Congress (IEC), Bangkok, Thailand. June 2019.

    • Chen, Y., Denby, C., Kreilkamp, B. A. K., Bracewell, M., Das, K., Fallon, N., Pegg, E., Mohanraj, R., Marson, A. G., Keller, S. S. Probabilistic mapping of thalamic nuclei atrophy in idiopathic generalised epilepsy.

    2018

    European Congress for Epileptology (ECE), Vienna, Austria. August 2018.

    • Keller, S. S. Invited talk: “Imaging the thalamus and thalamocortical networks in focal epilepsy: Significance for treatment outcome”.
    • Bryant, L., Alonazi, B. K., Bonilha, L., McKinnon, E., Jensen, J., Das, K., Marson, A. G., Sluming, V., Keller, S. S. Subcortical diffusional kurtosis imaging and antiepileptic drug treatment outcome in newly diagnosed focal epilepsy. Platform presentation.
    • Kreilkamp, B. A. K., Pasternak, O., Das, K., Wieshmann, U. C., Biswas, S., Marson, A. G., Keller, S. S. Automated free-water imaging analysis in patients with epilepsy and focal cortical dysplasia. Platform presentation.
    • Adan, G., Solomon, T., Turtle, L., Sinha, S., Saini, J., Manjon, J., Coupe, P., Marson, A. G., Keller, S. S. Quantitative MRI of the brain in patients with neurocysticercosis and epilepsy.
    • Chen, Y., Denby, C., Kreilkamp, B. A. K., Bracewell, M., Das, K., Marson, A. G., Keller, S. S. Altered large-scale resting-state functional networks in idiopathic generalised epilepsy.

    2017

    International Epilepsy Congress, Barcelona. September 2017.

    • Keller, S. S. Invited talk: “Network alterations in epilepsy revealed by quantitative MRI”.

    Organisation for Human Brain Mapping (OHBM), Vancouver, Canada. June 2017.

    • Kreilkamp, B. A. K., Das, K., Wieshmann, U. C., Biswas, S., Tyler, K., Kiel, S., Gould, S., Marson, A. G., Keller, S. S. Voxel-based MRI analysis can assist clinical diagnostics in patients with MRI-negative epilepsy.
    • Lisanti, L., Kreilkamp, B. A. K., Das, K., Wieshmann, U. C., Marson, A. G., Keller, S. S. Diffusion alterations of the Uncinate Fasciculus in non-lesional temporal lobe epilepsy.
    • Neason, M., Kreilkamp, B. A. K., Elkommos, S., Ziso, B., Das, K., Marson, A. G., Keller, S. S. Hippocampal and thalamic atrophy in patients with newly-diagnosed focal epilepsy.
    • Alonazi, B., Das, K., Keller, S. S., Marson, A. G., Sluming, V. Performance of Diffusion Kurtosis Imaging and Diffusion Tensor Imaging in patients with epilepsy.

    2016

    European Congress for Epileptology (ECE), Prague, Czech Republic. June 2016.

    • Keller, S. S., G. R. Glenn, Weber, B., Kreilkamp, B. A. K., Jensen, J., Richardson, M., Bonilha, L. Resection extent of the uncinate fasciculus and postoperative seizure outcome in temporal lobe epilepsy.
    • Kreilkamp, B. A. K., Das, K., Parkes, L., Wieshmann, U. C., Tyler, K., Kiel, S., Gould, S., Marson, A. G., Keller, S. S. Statistical cerebral blood flow mapping in patients with temporal lobe epilepsy.

    The Organisation of Human Brain Mapping (OHBM), Geneva, Switzerland. June 2016.

    • Keller, S. S., G. R. Glenn, Weber, B., Kreilkamp, B. A. K., Jensen, J., Richardson, M., Bonilha, L. Predicting outcome after surgery for temporal lobe epilepsy using Automated Fibre Quantification. Platform presentation.
    • Kreilkamp, B. A. K., Das, K., Wieshmann, U., Taylor, K., Kiel, S., Gould, S., Marson, A. G., Keller, S. S. Voxel-based myelinometry in patients with MRI-negative temporal lobe epilepsy.
    • Christopher D Whelan, Sophia Adams, Saud Alhusaini, Núria Bargalló, Emanuele Bartolini, Andrea Bernasconi, Boris Bernhardt, Karen Blackmon, Anna Calvo, Sarah Carr, Gianpiero L Cavalleri, Fernando Cendes, Antonio Cerasa, Andrea Cherubini, Luis Concha, Mark J Cook, Raul Cruces, Chantal Depondt, Patricia Desmond, Orrin Devinsky, Niels Föcke, Sonya Foley, Antonio Gambardella, Renzo Guerrini, Khalid Hamandi, Derrek P Hibar, Graeme Jackson, Neda Jahanshad, Reetta Kälviäinen, Simon S Keller, Raviteja Kotikalapudi, Patrick Kwan, Angelo Labate, Neda Ladbon-Bernasconi, Soenke Langner, Matteo Lenge, Kelly Leyden, Min Liu, Richard Q Loi, Mario Mascalchi, Carrie McDonald, Stefano Meletti, Laura Mirandola, Marcia Morita, Jillian Naylor, Terence O'Brien, Jose C Pariente, Yifan Ren, Mark Richardson, Andrea Ruggeri, Christian Rummel, Taavi Saavalainen, Margitta Seeck, Mira Semmelroch, Maria S Severino, Pasquale Striano, Thomas Thesen, Rhys Thomas, Manuela Tondelli, Manuela Tondelli, Domenica Tortora, Anna E Vaudano, Dennis Velakoulis, Lucy Vivash, Serge Vulliemoz, Bernd Weber, Roland Wiest, Clarissa Yasuda, Junsong Zhang, Paul M Thompson and Sanjay Sisodiya, for the ENIGMA-Epilepsy Working Group. ­2016. ENIGMA-Epilepsy: Brain volume comparisons between 963 epilepsy cases and 1,358 controls in 23 cohorts worldwide. Platform presentation.

    International Society for Magnetic Resonance in Medicine (ISMRM), Singapore. May 2016.

    • Glenn, G. R., Bonilha, L, Kreilkamp, B., Richardson, M. P., Weber, B., Keller, S. S. Automated fibre quantification of the fornix predicts outcome after surgery for intractable temporal lobe epilepsy. Platform presentation.
    • Glenn, G. R., Jensen, J. H., Keller, S. S., Helpern, J. A., Bonilha, L. Cytoarchitectonic abnormalities along white matter pathways in temporal lobe epilepsy: combining diffusional kurtosis imaging and automated fiber quantification.