Cellular and Molecular Physiology MPhil/PhD/MD

Major code: CYMR/CYPR/CYMD


Overview

The Department of Cellular and Molecular Physiology forms an integral part of the new Institute for Translational Medicine. Building on a long and prestigious history the department remains a leading international centre for research into the fundamental principles of human physiology. In the post genomic era physiology has acquired a new importance as a discipline which provides a valuable link between basic and translational research. In the Department of Cellular and Molecular Physiology we have recognised expertise in all aspects of modern physiology ranging from the regulation of gene expression to cell, tissue and whole organism biology. In essence, our research is focused around five key areas of expertise; each of which is related to a complementary area of clinical research or drug development.

Subject Overview

These include:

  • Cell physiology, with a focus on intracellular signalling, vesicular transport and the cell cycle;
  • Systems physiology, including the cancer microenvironment, gastric physiology, stem cell biology and developmental physiology;
  • Smooth muscle physiology, with research in reproductive physiology, ureteric microvessels, respiratory physiology and disease;
  • Neuronal signalling, integrating expertise in cell biology, structural biology and the use of model organisms to investigate aging, neurodegeneration and addiction;
  • Calcium signalling in health and disease, which is currently focused on the role of Ca2+ signalling, mitochondrial function and bioenergetics in pancreatitis and regulated secretion.

In addition, we are also developing new programs in vascular biology, including the therapeutic use of vascular stents and mechanisms of immune and cancer cell invasion. Together these programs provide an exciting and dynamic research environment which benefits from increasing collaboration with clinicians working in cancer research, reproductive medicine, child health and pancreatic research.

Key Facts

The Institute of Translational Medicine comprises six departments:
Biostatistics
Cellular and Molecular Physiology
Molecular and Clinical Pharmacology
Molecular and Clinical Cancer Medicine
Women’s and Children’s Health

The work of the Institute:
Takes place in the laboratory and in the clinic, forming a continuous cycle of scientific discovery and clinical research that’s yielding remarkable advances in healthcare provision.

A primary aim:
Is to provide the necessary infrastructure, facilities, professional support and environment to foster collaborative research between basic science and clinical science postgraduates.

The Institute draws on:
The established expertise within each Department to foster, develop and enhance translational medicine work streams and projects throughout the Institute as a whole.

Why The Department of Cellular and Molecular Physiology ?

A long and prestigious history

The Department of Cellular and Molecular Physiology (www.liv.ac.uk/physiology/) builds on a long and prestigious history and remains a leading international centre for research into the fundamental principles of human physiology. In the post genomic era, physiology has acquired a new importance as a discipline which provides a valuable link between basic and translational research.

Recognised expertise

In the Department we have recognised expertise in all aspects of modern physiology ranging from the regulation of gene expression to cell, tissue and whole organism biology. In essence, our research is focused around five key areas of expertise; each of which is related to a complementary area of clinical research or drug development.

An exciting and dynamic research environment

Together these programs provide an exciting and dynamic research environment which benefits from increasing collaboration with clinicians working in cancer research, reproductive medicine, child health and pancreatic research.