Dr Lakis Liloglou B.Sc.(hons), Ph.D.
Senior Lecturer in molecular oncology Molecular & Clinical Cancer Medicine
- +44 (0)151 794 8904 / +44 (0)151 794 8920 / +44 (0)151 794 8958 / +44 (0)151 794 9121
- Work email T.Liloglou@liverpool.ac.uk
Publications
Selected Publications
- A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer (Journal article - 2013)
- A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article - 2013)
- TPL2 kinase is a suppressor of lung carcinogenesis (Journal article - 2013)
- DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer (Journal article - 2012)
- UHRF1-Mediated Tumor Suppressor Gene Inactivation in Nonsmall Cell Lung Cancer (Journal article - 2011)
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2022
Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer (Journal article)
Rosenberger, A., Muttray, N., Hung, R. J., Christiani, D. C., Caporaso, N. E., Liu, G., . . . Consortium, I. N. T. E. G. R. A. L. -I. L. C. C. O. (2022). Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer. EUROPEAN JOURNAL OF MEDICAL RESEARCH, 27(1). doi:10.1186/s40001-022-00638-7Iam hiQ-a novel pair of accuracy indices for imputed genotypes (Journal article)
Rosenberger, A., Tozzi, V., Bickeboeller, H., & Consortium, I. N. T. E. G. R. A. L. -I. L. C. C. O. (2022). Iam hiQ-a novel pair of accuracy indices for imputed genotypes. BMC BIOINFORMATICS, 23(1). doi:10.1186/s12859-022-04568-32021
SAVER: sodium valproate for the epigenetic reprogramming of high-risk oral epithelial dysplasia-a phase II randomised control trial study protocol (Journal article)
McCarthy, C., Sacco, J., Fedele, S., Ho, M., Porter, S., Liloglou, T., . . . Shaw, R. (2021). SAVER: sodium valproate for the epigenetic reprogramming of high-risk oral epithelial dysplasia-a phase II randomised control trial study protocol. TRIALS, 22(1). doi:10.1186/s13063-021-05373-8Cyclic AMP Response Element Modulator-alpha Suppresses PD-1 Expression and Promotes Effector CD4(+) T Cells in Psoriasis (Journal article)
Hofmann, S. R., Carlsson, E., Kapplusch, F., Carvalho, A. L., Liloglou, T., Schulze, F., . . . Hedrich, C. M. (2021). Cyclic AMP Response Element Modulator-alpha Suppresses PD-1 Expression and Promotes Effector CD4(+) T Cells in Psoriasis. JOURNAL OF IMMUNOLOGY, 207(1), 55-64. doi:10.4049/jimmunol.2100240TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target (Journal article)
Kennedy, E., Coulter, E., Halliwell, E., Profitos-Peleja, N., Walsby, E., Clark, B., . . . Pepper, A. G. S. (2021). TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target. BLOOD, 137(22), 3064-3078. doi:10.1182/blood.2020005964A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1 (Journal article)
Jones, R., Wijesinghe, S., Wilson, C., Halsall, J., Liloglou, T., & Kanhere, A. (2021). A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1. ISCIENCE, 24(4). doi:10.1016/j.isci.2021.102273Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers (Journal article)
Lesseur, C., Ferreiro-Iglesias, A., McKay, J. D., Bosse, Y., Johansson, M., Gaborieau, V., . . . Brennan, P. (2021). Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. PLOS GENETICS, 17(3). doi:10.1371/journal.pgen.1009254Rare deleterious germline variants and risk of lung cancer (Journal article)
Liu, Y., Xia, J., McKay, J., Tsavachidis, S., Xiao, X., Spitz, M. R., . . . Amos, C. I. (2021). Rare deleterious germline variants and risk of lung cancer. NPJ PRECISION ONCOLOGY, 5(1). doi:10.1038/s41698-021-00146-72020
Balancing neurotrophin pathway and sortilin function: Its role in human disease (Journal article)
Al-Yozbaki, M., Acha-Sagredo, A., George, A., Liloglou, T., & Wilson, C. M. (2020). Balancing neurotrophin pathway and sortilin function: Its role in human disease. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1874(2). doi:10.1016/j.bbcan.2020.188429Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer (Journal article)
Giannoudis, A., Malki, M. I., Rudraraju, B., Mohhamed, H., Menon, S., Liloglou, T., . . . Palmieri, C. (2020). Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer. Breast Cancer Research, 22(1). doi:10.1186/s13058-020-01359-7Low protein intake during reproduction compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles (Journal article)
Kanakis, I., Alameddine, M., Scalabrin, M., van't Hof, R. J., Liloglou, T., Ozanne, S. E., . . . Vasilaki, A. (2020). Low protein intake during reproduction compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles. The FASEB Journal. doi:10.1096/fj.202001131RFibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties. (Journal article)
Barrera, L. N., Evans, A., Lane, B., Brumskill, S., Oldfield, F. E., Campbell, F., . . . Costello, E. (2020). Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties.. Cancer Research, 80(13), 2861-2873. doi:10.1158/0008-5472.can-19-3534Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines (Journal article)
Greaney-Davies, F. S. T., Risk, J., Robinson, M., Liloglou, T., Shaw, R., & Schache, A. (2020). Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines. Oral Oncology, 103. doi:10.1016/j.oraloncology.2020.104613Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis (Journal article)
Acha-Sagredo, A., Uko, B., Pantazi, P., Bediaga, N., Moschandrea, C., Rainbow, L., . . . Liloglou, T. (2020). Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. British Journal of Cancer, 122(7), 1050-1058. doi:10.1038/s41416-020-0742-9Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine (Journal article)
Al-Khafaji, A. S. K., Pantazi, P., Acha-Sagredo, A., Schache, A., Risk, J. M., Shaw, R. J., & Liloglou, T. (2020). Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine. ONCOLOGY LETTERS, 19(3), 2502-2507. doi:10.3892/ol.2020.113392019
Shared heritability and functional enrichment across six solid cancers (vol 10, 431, 2019) (Journal article)
Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., . . . Lindstrom, S. (2019). Shared heritability and functional enrichment across six solid cancers (vol 10, 431, 2019). NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-12095-8Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy (Journal article)
Veeramachaneni, R., Walker, T., Revil, T., De Weck, A., Badescu, D., O'Sullivan, J., . . . Thakker, N. (2019). Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-48229-7Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5(p)15.33 TERT-CLPTM1Ll Region (Journal article)
Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., . . . Gorlova, O. Y. (2019). Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5(p)15.33 TERT-CLPTM1Ll Region. JOURNAL OF THORACIC ONCOLOGY, 14(8), 1360-1369. doi:10.1016/j.jtho.2019.04.008Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD (Conference Paper)
Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., Den Hollander, A. I., de Jong, E., . . . Paraoan, L. (2019). Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from http://gateway.webofknowledge.com/Integrated Omics Profiling Reveals Novel Patterns of Epigenetic Programming in Cancer-Associated Myofibroblasts (Journal article)
Najgebauer, H., Liloglou, T., Jithesh, P. V., Giger, O. T., Varro, A., & Sanderson, C. M. (2019). Integrated Omics Profiling Reveals Novel Patterns of Epigenetic Programming in Cancer-Associated Myofibroblasts. Carcinogenesis, 40(4), 500-512. doi:10.1093/carcin/bgz001The expression signature of cancer-associated KRAB-ZNF factors identified in TCGA pan-cancer transcriptomic data (Journal article)
Machnik, M., Cylwa, R., Kielczewski, K., Biecek, P., Liloglou, T., Mackiewicz, A., & Oleksiewicz, U. (2019). The expression signature of cancer-associated KRAB-ZNF factors identified in TCGA pan-cancer transcriptomic data. MOLECULAR ONCOLOGY, 13(4), 701-724. doi:10.1002/1878-0261.12407Shared heritability and functional enrichment across six solid cancers (Journal article)
Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., . . . Lindstrom, S. (2019). Shared heritability and functional enrichment across six solid cancers. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-018-08054-4Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes. (Journal article)
Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., den Hollander, A. I., de Jong, E. K., . . . Paraoan, L. (2019). Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes.. Clinical epigenetics, 11(1), 6. doi:10.1186/s13148-019-0608-22018
Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer (Journal article)
Liu, Y., Lusk, C. M., Cho, M. H., Silverman, E. K., Qiao, D., Zhang, R., . . . Spitz, M. R. (2018). Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 13(10), 1483-1495. doi:10.1016/j.jtho.2018.06.0162017
Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (vol 6, 1751, 2017) (Journal article)
Heslop, J. A., Kia, R., Pridgeon, C. S., Sison-Young, R. L., Liloglou, T., Elmasry, M., . . . Park, B. K. (2017). Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (vol 6, 1751, 2017). STEM CELLS TRANSLATIONAL MEDICINE, 6(8). Retrieved from http://gateway.webofknowledge.com/Detection and quantitation of copy number variation in the voltagegated sodium channel gene of the mosquito Culex quinquefasciatus (Journal article)
Martins, W. F. S., Subramaniam, K., Steen, K., Mawejje, H., Liloglou, T., Donnelly, M. J., & Wilding, C. S. (2017). Detection and quantitation of copy number variation in the voltagegated sodium channel gene of the mosquito Culex quinquefasciatus. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-06080-8COL1A1, PRPF40A, and UCP2 correlate with hypoxia markers in non-small cell lung cancer. (Journal article)
Oleksiewicz, U., Liloglou, T., Tasopoulou, K. -M., Daskoulidou, N., Gosney, J. R., Field, J. K., & Xinarianos, G. (2017). COL1A1, PRPF40A, and UCP2 correlate with hypoxia markers in non-small cell lung cancer.. Journal of Cancer Research and Clinical Oncology, 143(7), 1133-1141. doi:10.1007/s00432-017-2381-yAURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer (Journal article)
Al-Khafaji, A. S. K., Marcus, M. W., Davies, M. P. A., Risk, J. M., Shaw, R. J., Field, J. K., & Liloglou, T. (2017). AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer. Oncology letters, 13(6), 4463-4468. doi:10.3892/ol.2017.6012Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (Journal article)
Heslop, J., Kia, R., Pridgeon, C., Sison-Young, R., Liloglou, T., Elmasry, M., . . . Park, B. K. (2017). Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells. Stem Cells Translational Medicine, 6(5), 1321-1331. doi:10.1002/sctm.16-0029Aurora B expression modulates paclitaxel response in non-small cell lung cancer. (Journal article)
Al-Khafaji, A. S., Davies, M. P., Risk, J. M., Marcus, M. W., Koffa, M., Gosney, J. R., . . . Liloglou, T. (2017). Aurora B expression modulates paclitaxel response in non-small cell lung cancer.. British journal of cancer, 116(05), 592-599. doi:10.1038/bjc.2016.4532016
Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma (Journal article)
Shaw, R., Christensen, A., Java, K., El Maddani, R., Liloglou, T., Asterios, T., . . . Robinson, M. (2016). Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma. ANNALS OF SURGICAL ONCOLOGY, 23(12), 4042-4048. doi:10.1245/s10434-016-5337-6Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis (Journal article)
Fjeld, K., Beer, S., Johnstone, M., Zimmer, C., Moessner, J., Ruffert, C., . . . Rosendahl, J. (2016). Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis. PLOS ONE, 11(11). doi:10.1371/journal.pone.0165567N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor (Journal article)
Logotheti, S., Khoury, N., Vlahopoulos, S. A., Skourti, E., Papaevangeliou, D., Liloglou, T., . . . Zoumpourlis, V. (2016). N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor. TRANSLATIONAL RESEARCH, 173, 58-73. doi:10.1016/j.trsl.2016.03.009Genome-Wide DNA Methylation and Gene Expression Profiling of Cancer-Associated Myofibroblasts (Thesis / Dissertation)
Najgebauer, H. (2016, June 16). Genome-Wide DNA Methylation and Gene Expression Profiling of Cancer-Associated Myofibroblasts.Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer (Journal article)
Poumpouridou, N., Acha-Sagredo, A., Goutas, N., Vlachodimitropoulos, D., Chatziioannidou, I., Lianidou, E., . . . Kroupis, C. (2016). Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer. CLINICAL BIOCHEMISTRY, 49(3), 253-259. doi:10.1016/j.clinbiochem.2015.10.009UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis (Journal article)
Abu-Alainin, W., Gana, T., Liloglou, L., Olayanju, A., Barrera Briceno, L., Ferguson, R., . . . Costello-Goldring, E. (2016). UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. Journal of Pathology, 238(3), 423-433. doi:10.1002/path.46652015
Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium (Journal article)
Huang, R., Wei, Y., Hung, R. J., Liu, G., Su, L., Zhang, R., . . . Christiani, D. C. (2015). Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBIOMEDICINE, 2(11), 1677-1685. doi:10.1016/j.ebiom.2015.09.031Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia (Journal article)
Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N., Wang, Y., . . . Hung, R. J. (2015). Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis, 36(11), 1314-1326. doi:10.1093/carcin/bgv128Involvement of long non coding RNAs in EGFR expression regulation in lung cancer (Conference Paper)
Pantazi, P., Liloglou, T., & Eliopoulos, A. (2015). Involvement of long non coding RNAs in EGFR expression regulation in lung cancer. In FEBS JOURNAL Vol. 282 (pp. 389). Retrieved from http://gateway.webofknowledge.com/Global hypomethylation of esophageal myofibroblasts is associated with accelerated tumor growth. (Conference Paper)
Giger, O. T., Brown, B., Liloglou, T., Jithesh, P. V., Dockray, J. G., & Varro, A. (2015). Global hypomethylation of esophageal myofibroblasts is associated with accelerated tumor growth.. In CANCER RESEARCH Vol. 75. doi:10.1158/1538-7445.CHTME14-B202014
Strategies for validation and testing of DNA methylation biomarkers (Journal article)
Noehammer, C., Pulverer, W., Hassler, M. R., Hofner, M., Wielscher, M., Vierlinger, K., . . . Weinhaeusel, A. (2014). Strategies for validation and testing of DNA methylation biomarkers. EPIGENOMICS, 6(6), 603-622. doi:10.2217/EPI.14.43SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma (Journal article)
Dhanda, J., Triantafyllou, A., Liloglou, T., Kalirai, H., Lloyd, B., Hanlon, R., . . . Risk, J. (2014). SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma. British Journal of Cancer, 111(11), 2114-2121. doi:10.1038/bjc.2014.500Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related. (Journal article)
Upile, N., Shaw, R., Jones, T., Goodyear, P., Liloglou, L., Risk, J., . . . Schache, A. (2014). Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.. The Laryngoscope, 124(12), 2739-2744. doi:10.1002/lary.24828Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study (Journal article)
Swale, A., Miyajima, F., Kolamunnage-Dona, R., Roberts, P., Little, M., Beeching, N., . . . Pirmohamed, M. (2014). Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study. Clinical Infectious Diseases, 59(10), 1429-1436. doi:10.1093/cid/ciu666Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). (Journal article)
Kim, C. H., Lee, Y. -C. A., Hung, R. J., McNallan, S. R., Cote, M. L., Lim, W. -Y., . . . Zhang, Z. -F. (2014). Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO).. International Journal of Cancer. Journal international du cancer, 135(8), 1918-1930. doi:10.1002/ijc.28835Epigenetic biomarkers in lung cancer (Journal article)
Liloglou, T., Bediaga, N. G., Brown, B. R. B., Field, J. K., & Davies, M. P. A. (2014). Epigenetic biomarkers in lung cancer. CANCER LETTERS, 342(2), 200-212. doi:10.1016/j.canlet.2012.04.018Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade (Journal article)
Bryant, D., Tristram, A., Liloglou, T., Hibbitts, S., Fiander, A., & Powell, N. (2014). Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade. JOURNAL OF CLINICAL VIROLOGY, 59(1), 24-29. doi:10.1016/j.jcv.2013.10.0292013
A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer (Journal article)
Sandoval, J., Mendez-Gonzalez, J., Nadal, E., Chen, G., Carmona, F. J., Sayols, S., . . . Esteller, M. (2013). A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer. JOURNAL OF CLINICAL ONCOLOGY, 31(32), 4140-+. doi:10.1200/JCO.2012.48.5516The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis (Journal article)
Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., . . . Gorgoulis, V. G. (2013). The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis. CELL DEATH AND DIFFERENTIATION, 20(11), 1485-1497. doi:10.1038/cdd.2013.76A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article)
Bediaga, N. G., Davies, M. P. A., Acha-Sagredo, A., Hyde, R., Raji, O. Y., Page, R., . . . Liloglou, T. (2013). A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material. BRITISH JOURNAL OF CANCER, 109(9), 2404-2411. doi:10.1038/bjc.2013.623A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer (Journal article)
Barh, D., Jain, N., Tiwari, S., Field, J. K., Padin-Iruegas, E., Ruibal, A., . . . Liloglou, T. (2013). A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer. BMC GENOMICS, 14. doi:10.1186/1471-2164-14-S6-S5Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines (Journal article)
Oleksiewicz, U., Liloglou, T., Tasopoulou, K. -M., Daskoulidou, N., Bryan, J., Gosney, J. R., . . . Xinarianos, G. (2013). Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines. HUMAN MOLECULAR GENETICS, 22(16), 3207-3217. doi:10.1093/hmg/ddt174Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16(INK4A), Cytoglobin, E-cadherin, and TMEFF2 (Journal article)
Shaw, R. J., Hobkirk, A. J., Nikolaidis, G., Woolgar, J. A., Triantafyllou, A., Brown, J. S., . . . Risk, J. M. (2013). Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16(INK4A), Cytoglobin, E-cadherin, and TMEFF2. ANNALS OF SURGICAL ONCOLOGY, 20(8), 2796-2802. doi:10.1245/s10434-012-2713-8Saliva collection methods for DNA biomarker analysis in oral cancer patients (Journal article)
Matthews, A. M., Kaur, H., Dodd, M., D'Souza, J., Liloglou, T., Shaw, R. J., & Risk, J. M. (2013). Saliva collection methods for DNA biomarker analysis in oral cancer patients. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 51(5), 394-398. doi:10.1016/j.bjoms.2012.09.017TPL2 kinase is a suppressor of lung carcinogenesis (Journal article)
Gkirtzimanaki, K., Gkouskou, K. K., Oleksiewicz, U., Nikolaidis, G., Vyrla, D., Liontos, M., . . . Eliopoulos, A. G. (2013). TPL2 kinase is a suppressor of lung carcinogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(16), E1470-E1479. doi:10.1073/pnas.1215938110Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma (Journal article)
Schache, A. G., Liloglou, T., Risk, J. M., Jones, T. M., Ma, X. -J., Wang, H., . . . Robinson, M. (2013). Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(6), 1332-1339. doi:10.1038/bjc.2013.63New perspectives to respiratory tract cancers (Journal article)
Marcus, M. W., Chen, Y., Liloglou, T., & Field, J. K. (2013). New perspectives to respiratory tract cancers. Head and Neck Oncology, 5(3).The epigenetic landscape of oral squamous cell carcinoma (Journal article)
Jithesh, P. V., Risk, J. M., Schache, A. G., Dhanda, J., Lane, B., Liloglou, T., & Shaw, R. J. (2013). The epigenetic landscape of oral squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(2), 370-379. doi:10.1038/bjc.2012.568Lung cancer epigenetics: emerging biomarkers. (Journal article)
Balgkouranidou, I., Liloglou, T., & Lianidou, E. S. (2013). Lung cancer epigenetics: emerging biomarkers.. Biomarkers in medicine, 7(1), 49-58. doi:10.2217/bmm.12.111The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia (Journal article)
Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia. BLOOD, 121(4), 628-637. doi:10.1182/blood-2012-01-405035The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia (Journal article)
Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia. Blood, 121, 628-637.2012
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Cassidy, A., Myles, J. P., Duffy, S. W., Liloglou, T., & Field, J. K. (2006). Family history and risk of lung cancer: age-at-diagnosis in cases and first-degree relatives. BRITISH JOURNAL OF CANCER, 95(9), 1288-1290. doi:10.1038/sj.bjc.6603386Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer (Journal article)
Xinarianos, G., McRonald, F. E., Risk, J. M., Bowers, N. L., Nikolaidis, G., Field, J. K., & Liloglou, T. (2006). Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer. HUMAN MOLECULAR GENETICS, 15(13), 2038-2044. doi:10.1093/hmg/ddl128Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing (Journal article)
Shaw, R. J., Akufo-Tetteh, E. K., Risk, J. M., Field, J. K., & Liloglou, T. (2006). Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing. NUCLEIC ACIDS RESEARCH, 34(11). doi:10.1093/nar/gkl424Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression (Journal article)
McRonald, F. E., Liloglou, T., Xinarianos, G., Hill, L., Rowbottom, L., Langan, J. E., . . . Risk, J. M. (2006). Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression. HUMAN MOLECULAR GENETICS, 15(8), 1271-1277. doi:10.1093/hmg/ddl042Promoter methylation of P16, RAR beta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing (Journal article)
Shaw, R. J., Liloglou, T., Rogers, S. N., Brown, J. S., Vaughan, E. D., Lowe, D., . . . Risk, J. M. (2006). Promoter methylation of P16, RAR beta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing. BRITISH JOURNAL OF CANCER, 94(4), 561-568. doi:10.1038/sj.bjc.6602972Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer (Journal article)
Cassidy, A., Myles, J. P., Liloglou, T., Duffy, S. W., & Field, J. K. (2006). Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY, 28(5), 1295-1301. Retrieved from http://gateway.webofknowledge.com/Down-regulation of the KIP family members p27 KIP1 and p57 KIP2 by SKP2 and the role of methylation in p57KIP2 (Journal article)
Pateras, I. S., Kotsinas, A., Liloglou, T., Nikolaidis, G., Foukas, P., Koutsami, M., . . . Gorgoulis, V. G. (2006). Down-regulation of the KIP family members p27 KIP1 and p57 KIP2 by SKP2 and the role of methylation in p57KIP2. Int J Cancer.Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: a novel approach using real-time PCR with melting curve analysis in histopathologic material. (Journal article)
Vageli, D., Daniil, Z., Dahabreh, J., Karagianni, E., Liloglou, T., Koukoulis, G., & Gourgoulianis, K. (2006). Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: a novel approach using real-time PCR with melting curve analysis in histopathologic material.. Oncology reports, 15(3), 557-564.2005
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry (Journal article)
Ehrich, M., Nelson, M. R., Stanssens, P., Zabeau, M., Liloglou, T., Xinarianos, G., . . . van den Boom, D. (2005). Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(44), 15785-15790. doi:10.1073/pnas.0507816102Abnormal CYGB expression and hypermethylation in non-small cell lung cancer (Journal article)
Liloglou, T., McRonald, F., Xinarianos, G., Bowers, N., Risk, J., & Field, J. (2005). Abnormal CYGB expression and hypermethylation in non-small cell lung cancer. LUNG CANCER, 49, S134. doi:10.1016/S0169-5002(05)80572-0Colorectal adenomas with a low frequency of ki-ras mutations: a sample from a population with a low mortality rate from colorectal cancer. (Journal article)
Kornaros, S., Liloglou, T., Politou, M., & Elemenoglou, I. (2005). Colorectal adenomas with a low frequency of ki-ras mutations: a sample from a population with a low mortality rate from colorectal cancer.. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 7(4), 323-326. doi:10.1111/j.1463-1318.2005.00809.xCheckpoint activation identifies genetic damage in precancerous lesions (Journal article)
Gorgoulis, V. G., Vassiliou, L. F., Venere, M., DiTullio, R. A., Yoneta, A., Herlyn, M., . . . Kletsas, D. (2005). Checkpoint activation identifies genetic damage in precancerous lesions. Cancer Biology and Therapy, 4(5).Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. (Journal article)
Gorgoulis, V. G., Vassiliou, L. -V. F., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Halazonetis, T. D. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.. Nature, 434(7035), 907-913. doi:10.1038/nature03485Methylation discriminators in NSCLC identified by a microarray based approach (Journal article)
Field, J. K., Liloglou, T., Warrak, S., Burger, M., Becker, E., Berlin, K., . . . Maier, S. (2005). Methylation discriminators in NSCLC identified by a microarray based approach. INTERNATIONAL JOURNAL OF ONCOLOGY, 27(1), 105-111. Retrieved from http://gateway.webofknowledge.com/2004
Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas. (Journal article)
Gorgoulis, V. G., Liloglou, T., Sigala, F., Korkolis, D., Yannoukakos, D., Papalambros, E., . . . Kotsinas, A. (2004). Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas.. Mutation research, 556(1-2), 143-150. doi:10.1016/j.mrfmmm.2004.07.008METH-2 silencing and promoter hypermethylation in NSCLC (Journal article)
Dunn, J. R., Panutsopulos, D., Shaw, M. W., Heighway, J., Dormer, R., Salmo, E. N., . . . Liloglou, T. (2004). METH-2 silencing and promoter hypermethylation in NSCLC. BRITISH JOURNAL OF CANCER, 91(6), 1149-1154. doi:10.1038/sj.bjc.6602107Glycine-extended gastrin promotes the growth of lung cancer (Journal article)
Koh, T. J., Field, J. K., Varro, A., Liloglou, T., Fielding, P., Cui, G. L., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. Cancer Research, 64(1), 196-201. Retrieved from http://cancerres.aacrjournals.org/cgi/reprint/64/1/196Glycine-extended gastrin promotes the growth of lung cancer (Journal article)
Koh, T. J., Field, J. K., Varro, A., Liloglou, L., Fielding, P., Cui, G., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. Cancer Research, 64(1), 196-201. doi:10.1158/0008-5472.CAN-03-2112Glycine-extended gastrin promotes the growth of lung cancer (Journal article)
Koh, T. J., Field, J. K., Varro, A., Liloglou, T., Fielding, P., Cui, G. L., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. CANCER RESEARCH, 64(1), 196-201. doi:10.1158/0008-5472.CAN-03-21122003
Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin. (Journal article)
Saridaki, Z., Liloglou, T., Zafiropoulos, A., Koumantaki, E., Zoras, O., & Spandidos, D. A. (2003). Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin.. The British journal of dermatology, 148(4), 638-648. doi:10.1046/j.1365-2133.2003.05230.xAbsence of mutations in the VHL gene but frequent loss of heterozygosity at 3p25-26 in non-small cell lung carcinomas (Journal article)
Miyakis, S., Liloglou, T., Kearney, S., Xinarianos, G., Spandidos, D. A., & Field, J. K. (2003). Absence of mutations in the VHL gene but frequent loss of heterozygosity at 3p25-26 in non-small cell lung carcinomas. LUNG CANCER, 39(3), 273-277. doi:10.1016/S0169-5002(02)00506-8Allelic imbalance at the DNA mismatch repair loci, hMSH2, hMLH1, hPMS1, hPMS2 and hMSH3, in squamous cell carcinoma of the head and neck (Journal article)
Nunn, J., Nagini, S., Risk, J. M., Prime, W., Maloney, P., Liloglou, T., . . . Field, J. K. (2003). Allelic imbalance at the DNA mismatch repair loci, hMSH2, hMLH1, hPMS1, hPMS2 and hMSH3, in squamous cell carcinoma of the head and neck. ORAL ONCOLOGY, 39(2), 115-129. doi:10.1016/S1368-8375(02)00028-3Fluorescent microsatellite analysis in bronchial lavage as a potential diagnostic tool for lung cancer. (Journal article)
Field, J. K., & Liloglou, T. (2003). Fluorescent microsatellite analysis in bronchial lavage as a potential diagnostic tool for lung cancer.. Methods in molecular medicine, 75, 251-262. doi:10.1385/1-59259-324-0:251In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree (Journal article)
Sikkink, S. K., Liloglou, T., Maloney, P., Gosney, J. R., & Field, J. K. (2003). In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree. INTERNATIONAL JOURNAL OF ONCOLOGY, 22(3), 589-595. Retrieved from http://gateway.webofknowledge.com/Method and nucleic acids for the analysis of a lung cell proliferative disorder (Patent)
Burger, M., Field, J. K., Genc, B. L., Liloglou, T., Lipscher, E., Maier, S., . . . Epigenomics AG. (2003). Method and nucleic acids for the analysis of a lung cell proliferative disorder.Microsatellite analysis in bronchial lavage and sputum as a diagnostic tool of lung cancer (Book)
Field, J. K., & Liloglou, T. (2003). Microsatellite analysis in bronchial lavage and sputum as a diagnostic tool of lung cancer (Vol. 2). B. Driscol (Ed.), NY: Humana Press.2002
p53 status correlates with the differential expression of the DNA mismatch repair protein MSH2 in non-small cell lung carcinoma (Journal article)
Xinarianos, G., Liloglou, T., Prime, W., Sourvinos, G., Karachristos, A., Gosney, J. R., . . . Field, J. K. (2002). p53 status correlates with the differential expression of the DNA mismatch repair protein MSH2 in non-small cell lung carcinoma. INTERNATIONAL JOURNAL OF CANCER, 101(3), 248-252. doi:10.1002/ijc.10598A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer (Journal article)
Liloglou, T., Walters, M., Maloney, P., Youngson, J., & Field, J. K. (2002). A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. LUNG CANCER, 37(2), 143-146. doi:10.1016/S0169-5002(02)00078-8Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps (Journal article)
Langan, J. E., Rowbottom, L., Liloglou, T., Field, J. K., & Risk, J. M. (2002). Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps. BIOTECHNIQUES, 33(2), 276-+. doi:10.2144/02332bm042001
Loss of heterozygosity on chromosomes 3, 9, 13 and 17, including the retinoblastoma locus, in uveal melanoma (Journal article)
Scholes, A. G. M., Liloglou, T., Maloney, P., Hagan, S., Nunn, J., Hiscott, P., . . . Field, J. K. (2001). Loss of heterozygosity on chromosomes 3, 9, 13 and 17, including the retinoblastoma locus, in uveal melanoma. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 42(11), 2472-2477. Retrieved from http://gateway.webofknowledge.com/Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas (Journal article)
Kotsinas, A., Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Kokotas, S., Liloglou, T., . . . Kittas, C. (2001). Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas. CANCER GENETICS AND CYTOGENETICS, 126(2), 147-154. doi:10.1016/S0165-4608(00)00407-6Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer (Journal article)
Sourvinos, G., Miyakis, S., Liloglou, T. L., Field, J. K., & Spandidos, D. A. (2001). Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer. TUMOR BIOLOGY, 22(3), 131-136. doi:10.1159/000050607Cancer-specific genomic instability in bronchial lavage: A molecular tool for lung cancer detection (Journal article)
Liloglou, T., Maloney, P., Xinarianos, G., Hulbert, M., Walshaw, M. J., Gosney, J. R., . . . Field, J. K. (2001). Cancer-specific genomic instability in bronchial lavage: A molecular tool for lung cancer detection. CANCER RESEARCH, 61(4), 1624-1628. Retrieved from http://gateway.webofknowledge.com/Deregulated expression of c-mos in non-small cell lung carcinomas: Relationship with p53 status, genomic instability, and tumor kinetics (Journal article)
Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Liloglou, T., Kokotas, S., Kastrinakis, N., . . . Field, J. K. (2001). Deregulated expression of c-mos in non-small cell lung carcinomas: Relationship with p53 status, genomic instability, and tumor kinetics. CANCER RESEARCH, 61(2), 538-549. Retrieved from http://gateway.webofknowledge.com/A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene (Journal article)
Kotsinas, A., Gorgoulis, V. G., Zacharatos, P., Liloglou, T., Leonardou, P., Brami, J., . . . Kittas, C. (2001). A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene. IN VIVO, 15(1), 105-108. Retrieved from http://gateway.webofknowledge.com/Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs) (Journal article)
Garinis, G. A., Gorgoulis, V. G., Mariatos, G., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2001). Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs). JOURNAL OF PATHOLOGY, 193(1), 55-65. doi:3.0.CO;2-#">10.1002/1096-9896(2000)9999:9999<::AID-PATH731>3.0.CO;2-#DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH731>3.0.CO;2-#
Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs). (Journal article)
Garinis, G. A., Gorgoulis, V. G., Mariatos, G., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2001). Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs).. The Journal of pathology, 193(1), 55-65. doi:3.0.co;2-#">10.1002/1096-9896(2000)9999:9999<::aid-path731>3.0.co;2-#DOI: 10.1002/1096-9896(2000)9999:9999<::aid-path731>3.0.co;2-#
Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma (Journal article)
Scholes, A. G., Liloglou, T., Maloney, P., Hagan, S., Nunn, J., Hiscott, P., . . . Field, J. K. (2001). Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma. Invest Ophthalmol Vis Sci, 42(11), 2472-2477.2000
K-ras point mutation detection in lung cancer: Comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification (Journal article)
Clayton, S. J., Scott, F. M., Walker, J., Callaghan, K., Haque, K., Liloglou, T., . . . Fox, J. C. (2000). K-ras point mutation detection in lung cancer: Comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification. CLINICAL CHEMISTRY, 46(12), 1929-1938. Retrieved from http://gateway.webofknowledge.com/Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma (Journal article)
Gorgoulis, V. G., Kotsinas, A., Zacharatos, P., Mariatos, G., Liloglou, T., Tsoli, E., . . . Kittas, C. (2000). Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma. CANCER, 89(9), 1933-1945. doi:3.3.CO;2-4">10.1002/1097-0142(20001101)89:9<1933::AID-CNCR9>3.3.CO;2-4DOI: 10.1002/1097-0142(20001101)89:9<1933::AID-CNCR9>3.3.CO;2-4
The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas (Journal article)
Miyakis, S., Sourvinos, G., Liloglou, T. L., Stathopoulos, G. P., Field, J. K., & Spandidos, D. A. (2000). The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas. INTERNATIONAL JOURNAL OF CANCER, 88(3), 503-505. doi:3.3.CO;2-0">10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.3.CO;2-0DOI: 10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.3.CO;2-0
The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas (Journal article)
Miyakis, S., Sourvinos, G., Liloglou, T. L., Stathopoulos, G. P., Field, J. K., & Spandidos, D. A. (2000). The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas. International Journal of Cancer, 88(3), 503-505. doi:3.0.CO;2-9">10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9DOI: 10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9
c-mos immunoreactivity is an indicator of good prognosis in lung cancer (Journal article)
Athanasiou, A., Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2000). c-mos immunoreactivity is an indicator of good prognosis in lung cancer. HISTOPATHOLOGY, 37(1), 45-54. doi:10.1046/j.1365-2559.2000.00898.xhMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas (Journal article)
Xinarianos, G., Liloglou, T., Prime, W., Maloney, P., Callaghan, J., Fielding, P., . . . Field, J. K. (2000). hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas. CANCER RESEARCH, 60(15), 4216-4221. Retrieved from http://gateway.webofknowledge.com/Allelic imbalance at the 5q14 locus is associated with decreased apoptotic rate in non-small cell lung carcinomas (NSCLCs). Possible synergistic effect with p53 gene alterations on apoptosis (Journal article)
Gorgoulis, V. G., Mariatos, G., Manolis, E. N., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2000). Allelic imbalance at the 5q14 locus is associated with decreased apoptotic rate in non-small cell lung carcinomas (NSCLCs). Possible synergistic effect with p53 gene alterations on apoptosis. LUNG CANCER, 28(3), 211-224. doi:10.1016/S0169-5002(99)00137-3Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease (Journal article)
Xinarianos, G., Scott, F. M., Liloglou, T., Prime, W., Turnbull, L., Walshaw, M., & Field, J. K. (2000). Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease. LUNG CANCER, 28(1), 37-42. doi:10.1016/S0169-5002(99)00111-7Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status (Journal article)
Mariatos, G., Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Vogiatzi, T., Rassidakis, G., . . . Kittas, C. (2000). Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status. INTERNATIONAL JOURNAL OF CANCER, 89(2), 133-141. doi:3.0.CO;2-C">10.1002/(SICI)1097-0215(20000320)89:2<133::AID-IJC6>3.0.CO;2-CDOI: 10.1002/(SICI)1097-0215(20000320)89:2<133::AID-IJC6>3.0.CO;2-C
Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs) (Journal article)
Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Mariatos, G., Liloglou, T., Vogiatzi, T., . . . Kittas, C. (2000). Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs). MOLECULAR MEDICINE, 6(3), 208-237. doi:10.1007/BF03402115Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status (Journal article)
Mariatos, G., Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Vogiatzi, T., Rassidakis, G., . . . Kittas, C. (2000). Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status. International Journal of Cancer, 86(3), 133-141. doi:3.0.co;2-c">10.1002/(sici)1097-0215(20000320)89:2<133::aid-ijc6>3.0.co;2-cDOI: 10.1002/(sici)1097-0215(20000320)89:2<133::aid-ijc6>3.0.co;2-c
High frequency of loss of heterozygosity on chromosome region 9p21-p22 but lack of p16INK4a/p19ARF mutations in greek patients with basal cell carcinoma of the skin. (Journal article)
Saridaki, Z., Koumantaki, E., Liloglou, T., Sourvinos, G., Papadopoulos, O., Zoras, O., & Spandidos, D. A. (2000). High frequency of loss of heterozygosity on chromosome region 9p21-p22 but lack of p16INK4a/p19ARF mutations in greek patients with basal cell carcinoma of the skin.. The Journal of investigative dermatology, 115(4), 719-725. doi:10.1046/j.1523-1747.2000.00098.xModulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment (Journal article)
Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (2000). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. ANTICANCER RESEARCH, 19(1A), 579-587. Retrieved from http://www.ncbi.nlm.nih.gov/Sensitivity and limitations of high throughput fluorescent microsatellite analysis for the detection of allelic imbalance: Application in lung tumors (Journal article)
Liloglou, T., Maloney, P., Xinarianos, G., Fear, S., & Field, J. K. (2000). Sensitivity and limitations of high throughput fluorescent microsatellite analysis for the detection of allelic imbalance: Application in lung tumors. INTERNATIONAL JOURNAL OF ONCOLOGY, 16(1), 5-14. Retrieved from http://gateway.webofknowledge.com/1999
Genetic alterations is bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer (Journal article)
Field, J. K., Liloglou, T., Xinarianos, G., Prime, W., Fielding, P., Walshaw, M. J., & Turnbull, L. (1999). Genetic alterations is bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer. CANCER RESEARCH, 59(11), 2690-2695. Retrieved from http://gateway.webofknowledge.com/Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1. (Journal article)
Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (1999). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.. Anticancer research, 19(1A), 579-587.Fractional allele loss indicates distinct genetic populations in the development of squamous cell carcinoma of the head and neck (SCCHN) (Journal article)
Nunn, J., Scholes, A. G. M., Liloglou, T., Nagini, S., Jones, A. S., Vaughan, E. D., . . . Field, J. K. (1999). Fractional allele loss indicates distinct genetic populations in the development of squamous cell carcinoma of the head and neck (SCCHN). CARCINOGENESIS, 20(12), 2219-2228. doi:10.1093/carcin/20.12.2219Microsatellite instability and p53 mutations in hepatocellular carcinoma. (Journal article)
Karachristos, A., Liloglou, T., Field, J. K., Deligiorgi, E., Kouskouni, E., & Spandidos, D. A. (1999). Microsatellite instability and p53 mutations in hepatocellular carcinoma.. Molecular cell biology research communications : MCBRC, 2(3), 155-161. doi:10.1006/mcbr.1999.0170Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. (Journal article)
Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (1999). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment.. Anticancer Res, 19(1A), 579-587.Telomerase activity in non-small cell lung carcinomas correlates with smoking status (Journal article)
Xinarianos, G., Scott, F. M., Liloglou, T., Prime, W., Callaghan, J., Gosney, J. R., & Field, J. K. (1999). Telomerase activity in non-small cell lung carcinomas correlates with smoking status. INTERNATIONAL JOURNAL OF ONCOLOGY, 15(5), 961-965. Retrieved from http://gateway.webofknowledge.com/1998
Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas - Relationship with p53 and MDM2 protein expression (Journal article)
Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Liloglou, T., Kyroudi, A., Veslemes, M., . . . Kittas, C. (1998). Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas - Relationship with p53 and MDM2 protein expression. AMERICAN JOURNAL OF PATHOLOGY, 153(6), 1749-1765. doi:10.1016/S0002-9440(10)65690-8Microsatellite instability and loss of heterozygosity in bronchial lavage specimens (Journal article)
Liloglou, T., Xinarianos, G., Prime, W., Walshaw, M., Turnbull, L., & Field, J. K. (1998). Microsatellite instability and loss of heterozygosity in bronchial lavage specimens. BRITISH JOURNAL OF CANCER, 78(2), 147-148. Retrieved from http://gateway.webofknowledge.com/Molecular pathological mechanisms in NSCLC and the assessment of individuals with a high risk of developing lung cancer (Book)
Field, J. K., Ross, H., Liloglou, T., Scott, F., Prime, W., Gosney, J. R., . . . Donnelly, R. J. (1998). Molecular pathological mechanisms in NSCLC and the assessment of individuals with a high risk of developing lung cancer. Retrieved from http://gateway.webofknowledge.com/Smoking correlates with the presence of p53 mutations in squamous cell carcinomas of the head and neck (SCCHN) (Conference Paper)
Liloglou., Scholes., Spandidos., Jones., Vaughan., & Field. (1998). Smoking correlates with the presence of p53 mutations in squamous cell carcinomas of the head and neck (SCCHN). In Clinical Otolaryngology and Allied Sciences Vol. 23 (pp. 268-269). Wiley. doi:10.1046/j.1365-2273.1998.0135m.xThe Knights of the Round Table hypothesis of tumour suppressor gene function - noble sacrifice or sexual dalliance: Genes, including p53, BRCA1/2 and RB have evolved by horizontal and vertical transmission of mating factor genes and are involved in gametogenesis, implantation, development and tumourigenesis (Journal article)
Gosden, C. M., Liloglou, T., Nunn, J., Gardener, D., Nickson, P., Crampton, J. M., & Field, J. K. (1998). The Knights of the Round Table hypothesis of tumour suppressor gene function - noble sacrifice or sexual dalliance: Genes, including p53, BRCA1/2 and RB have evolved by horizontal and vertical transmission of mating factor genes and are involved in gametogenesis, implantation, development and tumourigenesis. INTERNATIONAL JOURNAL OF ONCOLOGY, 12(1), 5-35. Retrieved from http://gateway.webofknowledge.com/1997
p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability (Journal article)
Liloglou, T., Scholes, A. G. M., Spandidos, D. A., Vaughan, E. D., Jones, A. S., & Field, J. K. (1997). p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability. CANCER RESEARCH, 57(18), 4070-4074. Retrieved from http://gateway.webofknowledge.com/p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck (Journal article)
Scholes, A. G. M., Liloglou, T., Snijders, P. J. F., Hart, C. A., Jones, A. S., Woolgar, J. A., . . . Field, J. K. (1997). p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck. International Journal of Cancer, 71(5), 796-799. doi:3.0.CO;2-6">10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6DOI: 10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6
p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck (Journal article)
Scholes, A. G. M., Liloglou, T., Snijders, P. J. F., Hart, C. A., Jones, A. S., Woolgar, J. A., . . . Field, J. K. (1997). p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck. INTERNATIONAL JOURNAL OF CANCER, 71(5), 796-799. doi:3.0.CO;2-6">10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6DOI: 10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6