Dr Lakis Liloglou B.Sc.(hons), Ph.D.

Selected Publications

1. A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer (Journal article - 2013)
2. A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article - 2013)
3. TPL2 kinase is a suppressor of lung carcinogenesis (Journal article - 2013)
4. DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer (Journal article - 2012)
5. UHRF1-Mediated Tumor Suppressor Gene Inactivation in Nonsmall Cell Lung Cancer (Journal article - 2011)

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2021

SAVER: sodium valproate for the epigenetic reprogramming of high-risk oral epithelial dysplasia-a phase II randomised control trial study protocol (Journal article)

McCarthy, C., Sacco, J., Fedele, S., Ho, M., Porter, S., Liloglou, T., . . . Shaw, R. (2021). SAVER: sodium valproate for the epigenetic reprogramming of high-risk oral epithelial dysplasia-a phase II randomised control trial study protocol. TRIALS, 22(1). doi:10.1186/s13063-021-05373-8

DOI: 10.1186/s13063-021-05373-8

Cyclic AMP Response Element Modulator-alpha Suppresses PD-1 Expression and Promotes Effector CD4(+) T Cells in Psoriasis (Journal article)

Hofmann, S. R., Carlsson, E., Kapplusch, F., Carvalho, A. L., Liloglou, T., Schulze, F., . . . Hedrich, C. M. (2021). Cyclic AMP Response Element Modulator-alpha Suppresses PD-1 Expression and Promotes Effector CD4(+) T Cells in Psoriasis. JOURNAL OF IMMUNOLOGY, 207(1), 55-64. doi:10.4049/jimmunol.2100240

DOI: 10.4049/jimmunol.2100240

TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target (Journal article)

Kennedy, E., Coulter, E., Halliwell, E., Profitos-Peleja, N., Walsby, E., Clark, B., . . . Pepper, A. G. S. (2021). TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target. BLOOD, 137(22), 3064-3078. doi:10.1182/blood.2020005964

DOI: 10.1182/blood.2020005964

A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1 (Journal article)

Jones, R., Wijesinghe, S., Wilson, C., Halsall, J., Liloglou, T., & Kanhere, A. (2021). A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1. ISCIENCE, 24(4). doi:10.1016/j.isci.2021.102273

DOI: 10.1016/j.isci.2021.102273

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers (Journal article)

Lesseur, C., Ferreiro-Iglesias, A., McKay, J. D., Bosse, Y., Johansson, M., Gaborieau, V., . . . Brennan, P. (2021). Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. PLOS GENETICS, 17(3). doi:10.1371/journal.pgen.1009254

DOI: 10.1371/journal.pgen.1009254

Rare deleterious germline variants and risk of lung cancer (Journal article)

Liu, Y., Xia, J., McKay, J., Tsavachidis, S., Xiao, X., Spitz, M. R., . . . Amos, C. I. (2021). Rare deleterious germline variants and risk of lung cancer. NPJ PRECISION ONCOLOGY, 5(1). doi:10.1038/s41698-021-00146-7

DOI: 10.1038/s41698-021-00146-7

2020

Balancing neurotrophin pathway and sortilin function: Its role in human disease (Journal article)

Al-Yozbaki, M., Acha-Sagredo, A., George, A., Liloglou, T., & Wilson, C. M. (2020). Balancing neurotrophin pathway and sortilin function: Its role in human disease. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1874(2). doi:10.1016/j.bbcan.2020.188429

DOI: 10.1016/j.bbcan.2020.188429

Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer (Journal article)

Giannoudis, A., Malki, M. I., Rudraraju, B., Mohhamed, H., Menon, S., Liloglou, T., . . . Palmieri, C. (2020). Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer. Breast Cancer Research, 22(1). doi:10.1186/s13058-020-01359-7

DOI: 10.1186/s13058-020-01359-7

Low protein intake during reproduction compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles (Journal article)

Kanakis, I., Alameddine, M., Scalabrin, M., van't Hof, R. J., Liloglou, T., Ozanne, S. E., . . . Vasilaki, A. (2020). Low protein intake during reproduction compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles. The FASEB Journal. doi:10.1096/fj.202001131R

DOI: 10.1096/fj.202001131R

Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties. (Journal article)

Barrera, L. N., Evans, A., Lane, B., Brumskill, S., Oldfield, F. E., Campbell, F., . . . Costello, E. (2020). Fibroblasts from Distinct Pancreatic Pathologies Exhibit Disease-Specific Properties.. Cancer Research, 80(13), 2861-2873. doi:10.1158/0008-5472.can-19-3534

DOI: 10.1158/0008-5472.can-19-3534

Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines (Journal article)

Greaney-Davies, F. S. T., Risk, J., Robinson, M., Liloglou, T., Shaw, R., & Schache, A. (2020). Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines. Oral Oncology, 103. doi:10.1016/j.oraloncology.2020.104613

DOI: 10.1016/j.oraloncology.2020.104613

Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis (Journal article)

Acha-Sagredo, A., Uko, B., Pantazi, P., Bediaga, N., Moschandrea, C., Rainbow, L., . . . Liloglou, T. (2020). Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. British Journal of Cancer, 122(7), 1050-1058. doi:10.1038/s41416-020-0742-9

DOI: 10.1038/s41416-020-0742-9

Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine (Journal article)

Al-Khafaji, A. S. K., Pantazi, P., Acha-Sagredo, A., Schache, A., Risk, J. M., Shaw, R. J., & Liloglou, T. (2020). Overexpression of HURP mRNA in head and neck carcinoma and association with in vitro response to vinorelbine. ONCOLOGY LETTERS, 19(3), 2502-2507. doi:10.3892/ol.2020.11339

DOI: 10.3892/ol.2020.11339

2019

Shared heritability and functional enrichment across six solid cancers (vol 10, 431, 2019) (Journal article)

Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., . . . Lindstrom, S. (2019). Shared heritability and functional enrichment across six solid cancers (vol 10, 431, 2019). NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-12095-8

DOI: 10.1038/s41467-019-12095-8

Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy (Journal article)

Veeramachaneni, R., Walker, T., Revil, T., De Weck, A., Badescu, D., O'Sullivan, J., . . . Thakker, N. (2019). Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-48229-7

DOI: 10.1038/s41598-019-48229-7

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5(p)15.33 TERT-CLPTM1Ll Region (Journal article)

Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., . . . Gorlova, O. Y. (2019). Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5(p)15.33 TERT-CLPTM1Ll Region. JOURNAL OF THORACIC ONCOLOGY, 14(8), 1360-1369. doi:10.1016/j.jtho.2019.04.008

DOI: 10.1016/j.jtho.2019.04.008

Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD (Conference Paper)

Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., Den Hollander, A. I., de Jong, E., . . . Paraoan, L. (2019). Whole genome methylation profiling of retinal pigment epithelium reveals differential methylation and gene expression associated with AMD. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 60. Retrieved from http://gateway.webofknowledge.com/

Integrated Omics Profiling Reveals Novel Patterns of Epigenetic Programming in Cancer-Associated Myofibroblasts (Journal article)

Najgebauer, H., Liloglou, T., Jithesh, P. V., Giger, O. T., Varro, A., & Sanderson, C. M. (2019). Integrated Omics Profiling Reveals Novel Patterns of Epigenetic Programming in Cancer-Associated Myofibroblasts. Carcinogenesis, 40(4), 500-512. doi:10.1093/carcin/bgz001

DOI: 10.1093/carcin/bgz001

The expression signature of cancer-associated KRAB-ZNF factors identified in TCGA pan-cancer transcriptomic data (Journal article)

Machnik, M., Cylwa, R., Kielczewski, K., Biecek, P., Liloglou, T., Mackiewicz, A., & Oleksiewicz, U. (2019). The expression signature of cancer-associated KRAB-ZNF factors identified in TCGA pan-cancer transcriptomic data. MOLECULAR ONCOLOGY, 13(4), 701-724. doi:10.1002/1878-0261.12407

DOI: 10.1002/1878-0261.12407

Shared heritability and functional enrichment across six solid cancers (Journal article)

Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., . . . Lindstrom, S. (2019). Shared heritability and functional enrichment across six solid cancers. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-018-08054-4

DOI: 10.1038/s41467-018-08054-4

Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes. (Journal article)

Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., den Hollander, A. I., de Jong, E. K., . . . Paraoan, L. (2019). Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes.. Clinical epigenetics, 11(1), 6. doi:10.1186/s13148-019-0608-2

DOI: 10.1186/s13148-019-0608-2

2018

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer (Journal article)

Liu, Y., Lusk, C. M., Cho, M. H., Silverman, E. K., Qiao, D., Zhang, R., . . . Spitz, M. R. (2018). Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 13(10), 1483-1495. doi:10.1016/j.jtho.2018.06.016

DOI: 10.1016/j.jtho.2018.06.016

2017

Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (vol 6, 1751, 2017) (Journal article)

Heslop, J. A., Kia, R., Pridgeon, C. S., Sison-Young, R. L., Liloglou, T., Elmasry, M., . . . Park, B. K. (2017). Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (vol 6, 1751, 2017). STEM CELLS TRANSLATIONAL MEDICINE, 6(8). Retrieved from http://gateway.webofknowledge.com/

Detection and quantitation of copy number variation in the voltagegated sodium channel gene of the mosquito Culex quinquefasciatus (Journal article)

Martins, W. F. S., Subramaniam, K., Steen, K., Mawejje, H., Liloglou, T., Donnelly, M. J., & Wilding, C. S. (2017). Detection and quantitation of copy number variation in the voltagegated sodium channel gene of the mosquito Culex quinquefasciatus. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-06080-8

DOI: 10.1038/s41598-017-06080-8

COL1A1, PRPF40A, and UCP2 correlate with hypoxia markers in non-small cell lung cancer. (Journal article)

Oleksiewicz, U., Liloglou, T., Tasopoulou, K. -M., Daskoulidou, N., Gosney, J. R., Field, J. K., & Xinarianos, G. (2017). COL1A1, PRPF40A, and UCP2 correlate with hypoxia markers in non-small cell lung cancer.. Journal of Cancer Research and Clinical Oncology, 143(7), 1133-1141. doi:10.1007/s00432-017-2381-y

DOI: 10.1007/s00432-017-2381-y

AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer (Journal article)

Al-Khafaji, A. S. K., Marcus, M. W., Davies, M. P. A., Risk, J. M., Shaw, R. J., Field, J. K., & Liloglou, T. (2017). AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer. Oncology letters, 13(6), 4463-4468. doi:10.3892/ol.2017.6012

DOI: 10.3892/ol.2017.6012

Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells (Journal article)

Heslop, J., Kia, R., Pridgeon, C., Sison-Young, R., Liloglou, T., Elmasry, M., . . . Park, B. K. (2017). Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells. Stem Cells Translational Medicine, 6(5), 1321-1331. doi:10.1002/sctm.16-0029

DOI: 10.1002/sctm.16-0029

Aurora B expression modulates paclitaxel response in non-small cell lung cancer. (Journal article)

Al-Khafaji, A. S., Davies, M. P., Risk, J. M., Marcus, M. W., Koffa, M., Gosney, J. R., . . . Liloglou, T. (2017). Aurora B expression modulates paclitaxel response in non-small cell lung cancer.. British journal of cancer, 116(05), 592-599. doi:10.1038/bjc.2016.453

DOI: 10.1038/bjc.2016.453

2016

Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma (Journal article)

Shaw, R., Christensen, A., Java, K., El Maddani, R., Liloglou, T., Asterios, T., . . . Robinson, M. (2016). Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma. ANNALS OF SURGICAL ONCOLOGY, 23(12), 4042-4048. doi:10.1245/s10434-016-5337-6

DOI: 10.1245/s10434-016-5337-6

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis (Journal article)

Fjeld, K., Beer, S., Johnstone, M., Zimmer, C., Moessner, J., Ruffert, C., . . . Rosendahl, J. (2016). Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis. PLOS ONE, 11(11). doi:10.1371/journal.pone.0165567

DOI: 10.1371/journal.pone.0165567

N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor (Journal article)

Logotheti, S., Khoury, N., Vlahopoulos, S. A., Skourti, E., Papaevangeliou, D., Liloglou, T., . . . Zoumpourlis, V. (2016). N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor. TRANSLATIONAL RESEARCH, 173, 58-73. doi:10.1016/j.trsl.2016.03.009

DOI: 10.1016/j.trsl.2016.03.009

Genome-Wide DNA Methylation and Gene Expression Profiling of Cancer-Associated Myofibroblasts (Thesis / Dissertation)

Najgebauer, H. (2016, June 16). Genome-Wide DNA Methylation and Gene Expression Profiling of Cancer-Associated Myofibroblasts.

Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer (Journal article)

Poumpouridou, N., Acha-Sagredo, A., Goutas, N., Vlachodimitropoulos, D., Chatziioannidou, I., Lianidou, E., . . . Kroupis, C. (2016). Development and validation of molecular methodologies to assess PALB2 expression in sporadic breast cancer. CLINICAL BIOCHEMISTRY, 49(3), 253-259. doi:10.1016/j.clinbiochem.2015.10.009

DOI: 10.1016/j.clinbiochem.2015.10.009

UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis (Journal article)

Abu-Alainin, W., Gana, T., Liloglou, L., Olayanju, A., Barrera Briceno, L., Ferguson, R., . . . Costello-Goldring, E. (2016). UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. Journal of Pathology, 238(3), 423-433. doi:10.1002/path.4665

DOI: 10.1002/path.4665

2015

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium (Journal article)

Huang, R., Wei, Y., Hung, R. J., Liu, G., Su, L., Zhang, R., . . . Christiani, D. C. (2015). Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBIOMEDICINE, 2(11), 1677-1685. doi:10.1016/j.ebiom.2015.09.031

DOI: 10.1016/j.ebiom.2015.09.031

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia (Journal article)

Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N., Wang, Y., . . . Hung, R. J. (2015). Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis, 36(11), 1314-1326. doi:10.1093/carcin/bgv128

DOI: 10.1093/carcin/bgv128

Involvement of long non coding RNAs in EGFR expression regulation in lung cancer (Conference Paper)

Pantazi, P., Liloglou, T., & Eliopoulos, A. (2015). Involvement of long non coding RNAs in EGFR expression regulation in lung cancer. In FEBS JOURNAL Vol. 282 (pp. 389). Retrieved from http://gateway.webofknowledge.com/

Global hypomethylation of esophageal myofibroblasts is associated with accelerated tumor growth. (Conference Paper)

Giger, O. T., Brown, B., Liloglou, T., Jithesh, P. V., Dockray, J. G., & Varro, A. (2015). Global hypomethylation of esophageal myofibroblasts is associated with accelerated tumor growth.. In CANCER RESEARCH Vol. 75. doi:10.1158/1538-7445.CHTME14-B20

DOI: 10.1158/1538-7445.CHTME14-B20

2014

Strategies for validation and testing of DNA methylation biomarkers (Journal article)

Noehammer, C., Pulverer, W., Hassler, M. R., Hofner, M., Wielscher, M., Vierlinger, K., . . . Weinhaeusel, A. (2014). Strategies for validation and testing of DNA methylation biomarkers. EPIGENOMICS, 6(6), 603-622. doi:10.2217/EPI.14.43

DOI: 10.2217/EPI.14.43

SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma (Journal article)

Dhanda, J., Triantafyllou, A., Liloglou, T., Kalirai, H., Lloyd, B., Hanlon, R., . . . Risk, J. (2014). SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma. British Journal of Cancer, 111(11), 2114-2121. doi:10.1038/bjc.2014.500

DOI: 10.1038/bjc.2014.500

Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related. (Journal article)

Upile, N., Shaw, R., Jones, T., Goodyear, P., Liloglou, L., Risk, J., . . . Schache, A. (2014). Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.. The Laryngoscope, 124(12), 2739-2744. doi:10.1002/lary.24828

DOI: 10.1002/lary.24828

Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study (Journal article)

Swale, A., Miyajima, F., Kolamunnage-Dona, R., Roberts, P., Little, M., Beeching, N., . . . Pirmohamed, M. (2014). Serum Mannose-Binding Lectin Concentration, but Not Genotype, Is Associated With Clostridium difficile Infection Recurrence: A Prospective Cohort Study. Clinical Infectious Diseases, 59(10), 1429-1436. doi:10.1093/cid/ciu666

DOI: 10.1093/cid/ciu666

Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO). (Journal article)

Kim, C. H., Lee, Y. -C. A., Hung, R. J., McNallan, S. R., Cote, M. L., Lim, W. -Y., . . . Zhang, Z. -F. (2014). Exposure to secondhand tobacco smoke and lung cancer by histological type: a pooled analysis of the International Lung Cancer Consortium (ILCCO).. International Journal of Cancer. Journal international du cancer, 135(8), 1918-1930. doi:10.1002/ijc.28835

DOI: 10.1002/ijc.28835

Epigenetic biomarkers in lung cancer (Journal article)

Liloglou, T., Bediaga, N. G., Brown, B. R. B., Field, J. K., & Davies, M. P. A. (2014). Epigenetic biomarkers in lung cancer. CANCER LETTERS, 342(2), 200-212. doi:10.1016/j.canlet.2012.04.018

DOI: 10.1016/j.canlet.2012.04.018

Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade (Journal article)

Bryant, D., Tristram, A., Liloglou, T., Hibbitts, S., Fiander, A., & Powell, N. (2014). Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade. JOURNAL OF CLINICAL VIROLOGY, 59(1), 24-29. doi:10.1016/j.jcv.2013.10.029

DOI: 10.1016/j.jcv.2013.10.029

2013

A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer (Journal article)

Sandoval, J., Mendez-Gonzalez, J., Nadal, E., Chen, G., Carmona, F. J., Sayols, S., . . . Esteller, M. (2013). A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer. JOURNAL OF CLINICAL ONCOLOGY, 31(32), 4140-+. doi:10.1200/JCO.2012.48.5516

DOI: 10.1200/JCO.2012.48.5516

The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis (Journal article)

Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., . . . Gorgoulis, V. G. (2013). The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis. CELL DEATH AND DIFFERENTIATION, 20(11), 1485-1497. doi:10.1038/cdd.2013.76

DOI: 10.1038/cdd.2013.76

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article)

Bediaga, N. G., Davies, M. P. A., Acha-Sagredo, A., Hyde, R., Raji, O. Y., Page, R., . . . Liloglou, T. (2013). A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material. BRITISH JOURNAL OF CANCER, 109(9), 2404-2411. doi:10.1038/bjc.2013.623

DOI: 10.1038/bjc.2013.623

A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer (Journal article)

Barh, D., Jain, N., Tiwari, S., Field, J. K., Padin-Iruegas, E., Ruibal, A., . . . Liloglou, T. (2013). A novel in silico reverse-transcriptomics-based identification and blood-based validation of a panel of sub-type specific biomarkers in lung cancer. BMC GENOMICS, 14. doi:10.1186/1471-2164-14-S6-S5

DOI: 10.1186/1471-2164-14-S6-S5

Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines (Journal article)

Oleksiewicz, U., Liloglou, T., Tasopoulou, K. -M., Daskoulidou, N., Bryan, J., Gosney, J. R., . . . Xinarianos, G. (2013). Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines. HUMAN MOLECULAR GENETICS, 22(16), 3207-3217. doi:10.1093/hmg/ddt174

DOI: 10.1093/hmg/ddt174

Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16(INK4A), Cytoglobin, E-cadherin, and TMEFF2 (Journal article)

Shaw, R. J., Hobkirk, A. J., Nikolaidis, G., Woolgar, J. A., Triantafyllou, A., Brown, J. S., . . . Risk, J. M. (2013). Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16(INK4A), Cytoglobin, E-cadherin, and TMEFF2. ANNALS OF SURGICAL ONCOLOGY, 20(8), 2796-2802. doi:10.1245/s10434-012-2713-8

DOI: 10.1245/s10434-012-2713-8

Saliva collection methods for DNA biomarker analysis in oral cancer patients (Journal article)

Matthews, A. M., Kaur, H., Dodd, M., D'Souza, J., Liloglou, T., Shaw, R. J., & Risk, J. M. (2013). Saliva collection methods for DNA biomarker analysis in oral cancer patients. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 51(5), 394-398. doi:10.1016/j.bjoms.2012.09.017

DOI: 10.1016/j.bjoms.2012.09.017

TPL2 kinase is a suppressor of lung carcinogenesis (Journal article)

Gkirtzimanaki, K., Gkouskou, K. K., Oleksiewicz, U., Nikolaidis, G., Vyrla, D., Liontos, M., . . . Eliopoulos, A. G. (2013). TPL2 kinase is a suppressor of lung carcinogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(16), E1470-E1479. doi:10.1073/pnas.1215938110

DOI: 10.1073/pnas.1215938110

Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma (Journal article)

Schache, A. G., Liloglou, T., Risk, J. M., Jones, T. M., Ma, X. -J., Wang, H., . . . Robinson, M. (2013). Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(6), 1332-1339. doi:10.1038/bjc.2013.63

DOI: 10.1038/bjc.2013.63

New perspectives to respiratory tract cancers (Journal article)

Marcus, M. W., Chen, Y., Liloglou, T., & Field, J. K. (2013). New perspectives to respiratory tract cancers. Head and Neck Oncology, 5(3).

The epigenetic landscape of oral squamous cell carcinoma (Journal article)

Jithesh, P. V., Risk, J. M., Schache, A. G., Dhanda, J., Lane, B., Liloglou, T., & Shaw, R. J. (2013). The epigenetic landscape of oral squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(2), 370-379. doi:10.1038/bjc.2012.568

DOI: 10.1038/bjc.2012.568

Lung cancer epigenetics: emerging biomarkers. (Journal article)

Balgkouranidou, I., Liloglou, T., & Lianidou, E. S. (2013). Lung cancer epigenetics: emerging biomarkers.. Biomarkers in medicine, 7(1), 49-58. doi:10.2217/bmm.12.111

DOI: 10.2217/bmm.12.111

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia (Journal article)

Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia. BLOOD, 121(4), 628-637. doi:10.1182/blood-2012-01-405035

DOI: 10.1182/blood-2012-01-405035

The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia (Journal article)

Giannoudis, A., Wang, L., Jorgensen, A. L., Xinarianos, G., Davies, A., Pushpakom, S., . . . Clark, R. E. (2013). The hOCT1 single nucleotide polymorphisms M420del and M408V alter imatinib uptake and modify clinical outcome in imatinib treated chronic myeloid leukaemia. Blood, 121, 628-637.

2012

DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer (Journal article)

Nikolaidis, G., Raji, O. Y., Markopoulou, S., Gosney, J. R., Bryan, J., Warburton, C., . . . Liloglou, T. (2012). DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer. CANCER RESEARCH, 72(22), 5692-5701. doi:10.1158/0008-5472.CAN-12-2309

DOI: 10.1158/0008-5472.CAN-12-2309

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls (Journal article)

Timofeeva, M. N., Hung, R. J., Rafnar, T., Christiani, D. C., Field, J. K., Bickeboeller, H., . . . Team, T. R. I. C. L. R. (2012). Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. HUMAN MOLECULAR GENETICS, 21(22), 4980-4995. doi:10.1093/hmg/dds334

DOI: 10.1093/hmg/dds334

DNA methylation biomarkers in biological fluids for early detection of respiratory tract cancer. (Journal article)

Markopoulou, S., Nikolaidis, G., & Liloglou, T. (2012). DNA methylation biomarkers in biological fluids for early detection of respiratory tract cancer.. Clinical chemistry and laboratory medicine, 50(10), 1723-1731. doi:10.1515/cclm-2012-0124

DOI: 10.1515/cclm-2012-0124

Progressive lung cancer determined by expression profiling and transcriptional regulation (Journal article)

Han, N., Dol, Z., Vasieva, O., Hyde, R., Liloglou, T., Raji, O., . . . Consortium, E. (2012). Progressive lung cancer determined by expression profiling and transcriptional regulation. INTERNATIONAL JOURNAL OF ONCOLOGY, 41(1), 242-252. doi:10.3892/ijo.2012.1421

DOI: 10.3892/ijo.2012.1421

Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates (Journal article)

Dietrich, D., Kneip, C., Raji, O., Lloglou, T., Seegebarth, A., Schlegel, T., . . . Field, J. K. (2012). Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates. INTERNATIONAL JOURNAL OF ONCOLOGY, 40(3), 825-832. doi:10.3892/ijo.2011.1264

DOI: 10.3892/ijo.2011.1264

2011

Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family (Journal article)

Oleksiewicz, U., Liloglou, T., Field, J. K., & Xinarianos, G. (2011). Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family. CELLULAR AND MOLECULAR LIFE SCIENCES, 68(23), 3869-3883. doi:10.1007/s00018-011-0764-9

DOI: 10.1007/s00018-011-0764-9

Neuroglobin and myoglobin in non-small cell lung cancer: Expression, regulation and prognosis (Journal article)

Oleksiewicz, U., Daskoulidou, N., Liloglou, T., Tasopoulou, K., Bryan, J., Gosney, J. R., . . . Xinarianos, G. (2011). Neuroglobin and myoglobin in non-small cell lung cancer: Expression, regulation and prognosis. LUNG CANCER, 74(3), 411-418. doi:10.1016/j.lungcan.2011.05.001

DOI: 10.1016/j.lungcan.2011.05.001

Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination (Journal article)

Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., . . . Shaw, R. J. (2011). Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination. CLINICAL CANCER RESEARCH, 17(19), 6262-6271. doi:10.1158/1078-0432.CCR-11-0388

DOI: 10.1158/1078-0432.CCR-11-0388

Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination (Journal article)

Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., . . . Shaw, R. J. (2011). Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination. Clinical Cancer Research, 17(19), 6262-6271. doi:10.1158/1078-0432.ccr-11-0388

DOI: 10.1158/1078-0432.ccr-11-0388

RE: P16 INK41 promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al. Oral Oncology 46 (2010) 734-739 (Journal article)

Shaw, R., Risk, J. M., & Liloglou, T. (2011). RE: P16 INK41 promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al. Oral Oncology 46 (2010) 734-739. ORAL ONCOLOGY, 47(8), 776. doi:10.1016/j.oraloncology.2010.10.014

DOI: 10.1016/j.oraloncology.2010.10.014

A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium (Journal article)

McKay, J. D., Truong, T., Gaborieau, V., Chabrier, A., Chuang, S. -C., Byrnes, G., . . . Brennan, P. (2011). A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium. PLOS GENETICS, 7(3). doi:10.1371/journal.pgen.1001333

DOI: 10.1371/journal.pgen.1001333

UHRF1-Mediated Tumor Suppressor Gene Inactivation in Nonsmall Cell Lung Cancer (Journal article)

Daskalos, A., Oleksiewicz, U., Filia, A., Nikolaidis, G., Xinarianos, G., Gosney, J. R., . . . Liloglou, T. (2011). UHRF1-Mediated Tumor Suppressor Gene Inactivation in Nonsmall Cell Lung Cancer. CANCER, 117(5), 1027-1037. doi:10.1002/cncr.25531

DOI: 10.1002/cncr.25531

Global DNA hypomethylation-induced Delta Np73 transcriptional activation in non-small cell lung cancer (Journal article)

Daskalos, A., Logotheti, S., Markopoulou, S., Xinarianos, G., Gosney, J. R., Kastania, A. N., . . . Liloglou, T. (2011). Global DNA hypomethylation-induced Delta Np73 transcriptional activation in non-small cell lung cancer. CANCER LETTERS, 300(1), 79-86. doi:10.1016/j.canlet.2010.09.009

DOI: 10.1016/j.canlet.2010.09.009

Quantitative promoter methylation differentiates Carcinoma ex Pleomorphic Adenoma from Pleomorphic Adenoma of the Salivary Glands (Journal article)

Schache, A., Hall, G., Woolgar, J. A., Nikolaidis, G., Triantafyllou, A., Lowe, D., . . . Liloglou, T. (2011). Quantitative promoter methylation differentiates Carcinoma ex Pleomorphic Adenoma from Pleomorphic Adenoma of the Salivary Glands. BAHNO ASM 2011, 1, 1.

2010

Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma (Journal article)

Schache, A. G., Hall, G., Woolgar, J. A., Nikolaidis, G., Triantafyllou, A., Lowe, D., . . . Liloglou, T. (2010). Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma. BRITISH JOURNAL OF CANCER, 103(12), 1846-1851. doi:10.1038/sj.bjc.6605953

DOI: 10.1038/sj.bjc.6605953

SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates (Journal article)

Schmidt, B., Liebenberg, V., Dietrich, D., Schlegel, T., Kneip, C., Seegebarth, A., . . . Field, J. K. (2010). SHOX2 DNA Methylation is a Biomarker for the diagnosis of lung cancer based on bronchial aspirates. BMC Cancer, 10(1). doi:10.1186/1471-2407-10-600

DOI: 10.1186/1471-2407-10-600

SHOX2 DNA Methylation is a Biomarker for the Diagnosis of Lung Cancer Based on Bronchial Aspirates (Journal article)

Schmidt, B., Liebenberg, V., Dietrich, D., Schlegel, T., Kneip, C., Seegebarth, A., . . . Field, J. K. (2010). SHOX2 DNA Methylation is a Biomarker for the Diagnosis of Lung Cancer Based on Bronchial Aspirates. BMC CANCER, 10. doi:10.1186/1471-2407-10-600

DOI: 10.1186/1471-2407-10-600

DNA methylation epigenotypes in breast cancer molecular subtypes (Journal article)

Bediaga, N. G., Acha-Sagredo, A., Guerra, I., Viguri, A., Albaina, C., Ruiz Diaz, I., . . . de Pancorbo, M. M. (2010). DNA methylation epigenotypes in breast cancer molecular subtypes. BREAST CANCER RESEARCH, 12(5). doi:10.1186/bcr2721

DOI: 10.1186/bcr2721

Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73 gamma in lung cancer (Journal article)

Logotheti, S., Michalopoulos, I., Sideridou, M., Daskalos, A., Kossida, S., Spandidos, D. A., . . . Zoumpourlis, V. (2010). Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73 gamma in lung cancer. FEBS JOURNAL, 277(14), 3014-3027. doi:10.1111/j.1742-4658.2010.07710.x

DOI: 10.1111/j.1742-4658.2010.07710.x

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals (Journal article)

Lips, E. H., Gaborieau, V., McKay, J. D., Chabrier, A., Hung, R. J., Boffetta, P., . . . Study, E. P. I. C. (2010). Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 39(2), 563-577. doi:10.1093/ije/dyp288

DOI: 10.1093/ije/dyp288

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer (Journal article)

Shaw, R. J., Risk, J. M., & Liloglou, T. (2010). Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. AACR Cancer Epigenetics Special Conference, Puerto Rico, Jan 2010, n/a, n/a.

Detection of DNA methylation changes in body fluids. (Journal article)

Liloglou, T., & Field, J. K. (2010). Detection of DNA methylation changes in body fluids.. Advances in genetics, 71, 177-207. doi:10.1016/b978-0-12-380864-6.00006-7

DOI: 10.1016/b978-0-12-380864-6.00006-7

UHRF1-mediated tumor suppressor gene inactivation in non-small cell lung cancer (Journal article)

Daskalos, A., Oleksiewicz, U., Filia, A., Nikolaidis, G., Xinarianos, G., Gosney, J. R., . . . Liloglou, T. (2010). UHRF1-mediated tumor suppressor gene inactivation in non-small cell lung cancer. Cancer, 117(5), 1027-1037.

2009

EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration (Journal article)

Field, J. K., Liloglou, T., Niaz, A., Bryan, J., Gosney, J. R., Giles, T., . . . Collaborators, E. U. E. L. C. (2009). EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration. EUROPEAN RESPIRATORY JOURNAL, 34(6), 1477-1486. doi:10.1183/09031936.00077809

DOI: 10.1183/09031936.00077809

Cancer diagnosis in first-degree relatives and non-small cell lung cancer risk: Results from a multi-centre case-control study in Europe (Journal article)

Cassidy, A., Balsan, J., Vesin, A., Wu, X., Liloglou, T., Brambilla, C., . . . Consortium, E. U. E. L. C. (2009). Cancer diagnosis in first-degree relatives and non-small cell lung cancer risk: Results from a multi-centre case-control study in Europe. EUROPEAN JOURNAL OF CANCER, 45(17), 3047-3053. doi:10.1016/j.ejca.2009.05.006

DOI: 10.1016/j.ejca.2009.05.006

Molecular features, markers, drug targets, and prospective targeted therapeutics in cardiac myxoma. (Journal article)

Barh, D., Kumar, A., Chatterjee, S., & Liloglou, T. (2009). Molecular features, markers, drug targets, and prospective targeted therapeutics in cardiac myxoma.. Current cancer drug targets, 9(6), 705-716. doi:10.2174/156800909789271549

DOI: 10.2174/156800909789271549

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy. (Journal article)

Dunn, J., Baborie, A., Alam, F., Joyce, K., Moxham, M., Sibson, R., . . . Walker, C. (2009). Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy.. British journal of cancer, 101(1), 124-131. doi:10.1038/sj.bjc.6605127

DOI: 10.1038/sj.bjc.6605127

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer (Journal article)

Shaw, R. J., Omar, M. M., Rokadiya, S., Kogera, F. A., Lowe, D., Hall, G. L., . . . Risk, J. M. (2009). Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. BRITISH JOURNAL OF CANCER, 101(1), 139-144. doi:10.1038/sj.bjc.6605121

DOI: 10.1038/sj.bjc.6605121

A Novel Type of p53 Pathway Dysfunction in Chronic Lymphocytic Leukemia Resulting from Two Interacting Single Nucleotide Polymorphisms within the p21 Gene (Journal article)

Johnson, G. G., Sherrington, P. D., Carter, A., Lin, K., Liloglou, T., Field, J. K., & Pettitt, A. R. (2009). A Novel Type of p53 Pathway Dysfunction in Chronic Lymphocytic Leukemia Resulting from Two Interacting Single Nucleotide Polymorphisms within the p21 Gene. CANCER RESEARCH, 69(12), 5210-5217. doi:10.1158/0008-5472.CAN-09-0627

DOI: 10.1158/0008-5472.CAN-09-0627

Fragile Histidine Triad Gene Inactivation in Lung Cancer The European Early Lung Cancer Project (Journal article)

Verri, C., Roz, L., Conte, D., Liloglou, T., Livio, A., Vesin, A., . . . Consortium, E. U. E. L. C. (2009). Fragile Histidine Triad Gene Inactivation in Lung Cancer The European Early Lung Cancer Project. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179(5), 396-401. doi:10.1164/rccm.200807-1153OC

DOI: 10.1164/rccm.200807-1153OC

EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration. (Journal article)

Field, J. K., Liloglou, T., Niaz, A., Bryan, J., Gosney, J. R., Giles, T., . . . EUELC Collaborators. (2009). EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration.. Eur Respir J, 34(6), 1477-1486.

Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer (Journal article)

Daskalos, A., Nikolaidis, G., Xinarianos, G., Savvari, P., Cassidy, A., Zakopoulou, R., . . . Liloglou, T. (2009). Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. INTERNATIONAL JOURNAL OF CANCER, 124(1), 81-87. doi:10.1002/ijc.23849

DOI: 10.1002/ijc.23849

2008

Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene (Journal article)

Shivapurkar, N., Stastny, V., Okumura, N., Girard, L., Xie, Y., Prinsen, C., . . . Gazdar, A. F. (2008). Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. CANCER RESEARCH, 68(18), 7448-7456. doi:10.1158/0008-5472.CAN-08-0565

DOI: 10.1158/0008-5472.CAN-08-0565

p16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia (Journal article)

Hall, G. L., Shaw, R. J., Field, E. A., Rogers, S. N., Sutton, D. N., Woolgar, J. A., . . . Risk, J. M. (2008). p16 promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(8), 2174-2179. doi:10.1158/1055-9965.EPI-07-2867

DOI: 10.1158/1055-9965.EPI-07-2867

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 (Journal article)

Hung, R. J., Mckay, J. D., Gaborieau, V., Boffetta, P., Hashibe, M., Zaridze, D., . . . Brennan, P. (2008). A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. NATURE, 452(7187), 633-637. doi:10.1038/nature06885

DOI: 10.1038/nature06885

The role of pyrosequencing in head and neck cancer epigenetics - Correlation of quantitative methylation data with gene expression (Journal article)

Shaw, R. J., Hall, G. L., Lowe, D., Liloglou, T., Field, J. K., Sloan, P., & Risk, J. M. (2008). The role of pyrosequencing in head and neck cancer epigenetics - Correlation of quantitative methylation data with gene expression. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 134(3), 251-256. doi:10.1001/archoto.2007.50

DOI: 10.1001/archoto.2007.50

The LLP risk model: an individual risk prediction model for lung cancer (Journal article)

Cassidy, A., Myles, J. P., van Tongeren, M., Page, R. D., Liloglou, T., Duffy, S. W., & Field, J. K. (2008). The LLP risk model: an individual risk prediction model for lung cancer. BRITISH JOURNAL OF CANCER, 98(2), 270-276. doi:10.1038/sj.bjc.6604158

DOI: 10.1038/sj.bjc.6604158

A single UK centre study of temozolomide and radiotherapy in glioblastoma patients (Conference Paper)

Dunn, J., Allam, F., Joyce, K., Wong, H., Baborie, A., Brodbelt, A., . . . Walker, C. (2008). A single UK centre study of temozolomide and radiotherapy in glioblastoma patients. In NCRI (Ed.), National Cancer Research Institute Cancer Conference 2008 (pp. B8). Birmingham: NCRI. Retrieved from http://www.ncri.org.uk/ncriconference/2008abstracts/abstracts/B8.htm

Aberrant methylation of both Tp73 promoters in non-small cell lung cancer (Conference Paper)

Liloglou, T., Daskalos, A., Nikolaidis, G., Xinarianos, G., & Field, J. K. (2008). Aberrant methylation of both Tp73 promoters in non-small cell lung cancer. In 101st AACR Annual Meeting (pp. P4268). San Diego, CA: AACR.

Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. (Conference Paper)

Shivapurkar, N., Stastny, V., Okumura, N., Girard, L., Xie, Y., Prinsen, C., . . . Gazdar, A. (2008). Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.. In 101st AACR Annual Meeting (pp. LB165). San Diego, CA: AACR.

Differential expression and promoter methylation of globin family genes in lung cancer (Conference Paper)

Babiszkiewicz, U., Liloglou, T., Field, J. K., & Xinarianos, G. (2008). Differential expression and promoter methylation of globin family genes in lung cancer. In NCRI Annual Meeting 2008 (pp. A137). Birmingham: NCRI.

Differential expression of gastrin (GAST) in non-small cell lung cancer (Conference Paper)

Xinarianos, G., Daskalos, A., Nikolaidis, G., Varro, A., Field, J., & Liloglou, T. (2008). Differential expression of gastrin (GAST) in non-small cell lung cancer. In 101st AACR Annual Meeting (pp. P3550). San Diego, CA: AACR.

Epigenetic deregulation of DIRAS3 in non-small cell lung cancer (Conference Paper)

Liloglou, T., Markopoulou, S., Daskalos, A., Nikolaidis, G., Xinarianos, G., Vageli, D., & Gourgoulianis, K. (2008). Epigenetic deregulation of DIRAS3 in non-small cell lung cancer. In NCRI Annual Meeting 2008 (pp. A140). Birmingham: NCRI.

Hypomethylation of LINE-1 and Alu-PV retrotransposble elements in lung cancer (Conference Paper)

Xinarianos, G., Daskalos, A., Nikolaidis, G., Savvari, P., Cassidy, A., Zakopoulou, R., . . . Liloglou, T. (2008). Hypomethylation of LINE-1 and Alu-PV retrotransposble elements in lung cancer. In NCRI Annual Meeting 2008 (pp. A138). Birmingham: NCRI.

Investigating the role of MDM2 in regulation of methylation (Conference Paper)

Maguire, M., Nield, P., Devling, T., Jenkins, R., Park, K., Polanski, R., . . . Boyd, M. (2008). Investigating the role of MDM2 in regulation of methylation. In NCRI Annual Meeting 2008 (pp. C75). Birmingham: NCRI.

Lung cancer susceptibility locus at 5p15.33 (Journal article)

McKay, J. D., Hung, R. J., Gaborieau, V., Boffetta, P., Chabrier, A., Byrnes, G., . . . Study, E. P. I. C. (2008). Lung cancer susceptibility locus at 5p15.33. NATURE GENETICS, 40(12), 1404-1406. doi:10.1038/ng.254

DOI: 10.1038/ng.254

Quantitative pyrosequencing methylation assay (PMA): correlation with gene expression in head and neck cancer (Conference Paper)

Shaw, R., Hall, G., Lowe, D., Liloglou, T., Field, J. K., Sloan, P., & Risk, J. (2008). Quantitative pyrosequencing methylation assay (PMA): correlation with gene expression in head and neck cancer. In NCRI Annual Meeting 2008 (pp. A103). Birmingham: NCRI.

qMSP assay development for early lung cancer detection (Conference Paper)

Nikolaidis, G., Markopoulou, S., Daskalos, A., Xinarianos, G., Field, J., & Liloglou, T. (2008). qMSP assay development for early lung cancer detection. In NCRI Annual Meeting 2008 (pp. A146). Birmingham: NCRI.

2007

Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma (Journal article)

Shaw, R. J., Hall, G. L., Woolgar, J. A., Lowe, D., Rogers, S. N., Field, J. K., . . . Risk, J. M. (2007). Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 45(8), 617-622. doi:10.1016/j.bjoms.2007.04.015

DOI: 10.1016/j.bjoms.2007.04.015

CpG island methylation phenotype (CIMP) in oral cancer: associated with a marked inflammatory response and less aggressive tumour biology. (Journal article)

Shaw, R. J., Hall, G. L., Lowe, D., Bowers, N. L., Liloglou, T., Field, J. K., . . . Risk, J. M. (2007). CpG island methylation phenotype (CIMP) in oral cancer: associated with a marked inflammatory response and less aggressive tumour biology.. Oral oncology, 43(9), 878-886. doi:10.1016/j.oraloncology.2006.10.006

DOI: 10.1016/j.oraloncology.2006.10.006

“CIMP” in head and neck cancer (Journal article)

Shaw, R., Hall, G. L., Lowe, D., Bowers, N. L., Liloglou, T., Field, J. K., . . . Risk, J. M. (2007). “CIMP” in head and neck cancer. British Journal of Oral and Maxillofacial Surgery, 45(7), e42-e43. doi:10.1016/j.bjoms.2007.07.041

DOI: 10.1016/j.bjoms.2007.07.041

Seizure 6-like (SEZ6L) gene and risk for lung cancer (Journal article)

Gorlov, I. P., Meyer, P., Lilogiou, T., Myles, J., Boettger, M. B., Cassidy, A., . . . Amos, C. I. (2007). Seizure 6-like (SEZ6L) gene and risk for lung cancer. CANCER RESEARCH, 67(17), 8406-8411. doi:10.1158/0008-5472.CAN-06-4784

DOI: 10.1158/0008-5472.CAN-06-4784

Biomarkers and risk models for stratification of high risk individuals (Journal article)

Field, J. K., Cassidy, A., Miles, J., Liloglou, T., Xinarianos, G., Smith, D., . . . Duffy, S. (2007). Biomarkers and risk models for stratification of high risk individuals. JOURNAL OF THORACIC ONCOLOGY, 2(8), S176. doi:10.1097/01.JTO.0000282955.20898.72

DOI: 10.1097/01.JTO.0000282955.20898.72

'Analysis of GSTM4 in non-small cell lung cancer' (Conference Paper)

Xinarianos, G., Nikolaidis, G., Wu, H., Cassidy, A., Myles, J. P., Duffy, S. W., . . . Liloglou, T. (2007). 'Analysis of GSTM4 in non-small cell lung cancer'. In American Association for Cancer Research Annual Meeting Vol. 48 (pp. 311). Los Angeles: American Association of Cancer Research.

'GAST gene expression is upregulated in non-small cell lung cancer (Conference Paper)

Liloglou, T., Daskalos, A., Xinarianos, G., Nikolaidis, G., Varro, A., & Field, J. K. (2007). 'GAST gene expression is upregulated in non-small cell lung cancer. In National Cancer Research Institute Conference (pp. 86). Birmingham: National Cancer Research Institute.

'Hypermethylation of endothelin receptor type B (EDRNB) in non-small cell lung cancer' (Conference Paper)

Knight, L., Burrage, J., Bujac, S., Gibson, N., Ellison, G., Growcott, J., . . . Liloglou, T. (2007). 'Hypermethylation of endothelin receptor type B (EDRNB) in non-small cell lung cancer'. In National Cancer Research Institute (pp. 88). Birmingham: National Cancer Research Institute.

'Hypermethylation of endothelin receptor type B (EDRNB) is a frequent event in non-small cell lung cancer (Conference Paper)

Knight, L. J., Gibson, N., Ellison, G., Growcott, J., Brooks, N., Hughes, A. M., . . . Field, J. K. (2007). 'Hypermethylation of endothelin receptor type B (EDRNB) is a frequent event in non-small cell lung cancer. In American Association for Cancer Research Annual Meeting Vol. 48 (pp. 429). Los Angeles: American Association of Cancer Research.

'Liverpool lung project:lung cancer risk prediction model (Conference Paper)

Field, J. K., Cassidy, A., Myles, J., Liloglou, T., Xinarianos, G., Smith, D., . . . Duffy, S. (2007). 'Liverpool lung project:lung cancer risk prediction model. In American Association for Cancer Research Annual Meeting Vol. 48 (pp. 402). Los Angeles: American Association of Cancer Research.

'Molecular analysis of the GSTM4 gene in lung cancer' (Conference Paper)

Xinarianos, G., Nikolaidis, G., Wu, H., Myles, J. P., Duffy, S. W., Field, J. K., & Liloglou, T. (2007). 'Molecular analysis of the GSTM4 gene in lung cancer'. In National Cancer Research Institute Conference (pp. 92). Birmingham: National Cancer Research Institute.

Lung cancer risk prediction: A tool for early detection (Journal article)

Cassidy, A., Duffy, S. W., Myles, J. P., Liloglou, T., & Field, J. K. (2007). Lung cancer risk prediction: A tool for early detection. INTERNATIONAL JOURNAL OF CANCER, 120(1), 1-6. doi:10.1002/ijc.22331

DOI: 10.1002/ijc.22331

Seizure 6-like (SEZ6L) gene and risk for lung cancer (Journal article)

Gorlov, I. P., Meyer, P., Liloglou, T., Myles, J., Boettger, M. B., Cassidy, A., . . . Amos, C. I. (2007). Seizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Res, 67(17), 8406-8411. doi:10.1158/0008-5472.CAN-06-4784

DOI: 10.1158/0008-5472.CAN-06-4784

2006

Downregulation of the KIP family members p27(KIP1) and p57(KIP2) by SKP2 and the role of methylation in p57(KIP2) inactivation in nonsmall cell lung cancer (Journal article)

Pateras, I. S., Apostolopoulou, K., Koutsami, M., Evangelou, K., Tsantoulis, P., Liloglou, T., . . . Gorgoulis, V. G. (2006). Downregulation of the KIP family members p27(KIP1) and p57(KIP2) by SKP2 and the role of methylation in p57(KIP2) inactivation in nonsmall cell lung cancer. INTERNATIONAL JOURNAL OF CANCER, 119(11), 2546-2556. doi:10.1002/ijc.22214

DOI: 10.1002/ijc.22214

Cytosine methylation profiles as a molecular marker in non-small cell lung cancer (Journal article)

Ehrich, M., Field, J. K., Liloglou, T., Xinarianos, G., Oeth, P., Nelson, M. R., . . . van den Boom, D. (2006). Cytosine methylation profiles as a molecular marker in non-small cell lung cancer. CANCER RESEARCH, 66(22), 10911-10918. doi:10.1158/0008-5472.CAN-06-0400

DOI: 10.1158/0008-5472.CAN-06-0400

Family history and risk of lung cancer: age-at-diagnosis in cases and first-degree relatives (Journal article)

Cassidy, A., Myles, J. P., Duffy, S. W., Liloglou, T., & Field, J. K. (2006). Family history and risk of lung cancer: age-at-diagnosis in cases and first-degree relatives. BRITISH JOURNAL OF CANCER, 95(9), 1288-1290. doi:10.1038/sj.bjc.6603386

DOI: 10.1038/sj.bjc.6603386

Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer (Journal article)

Xinarianos, G., McRonald, F. E., Risk, J. M., Bowers, N. L., Nikolaidis, G., Field, J. K., & Liloglou, T. (2006). Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer. HUMAN MOLECULAR GENETICS, 15(13), 2038-2044. doi:10.1093/hmg/ddl128

DOI: 10.1093/hmg/ddl128

Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing (Journal article)

Shaw, R. J., Akufo-Tetteh, E. K., Risk, J. M., Field, J. K., & Liloglou, T. (2006). Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing. NUCLEIC ACIDS RESEARCH, 34(11). doi:10.1093/nar/gkl424

DOI: 10.1093/nar/gkl424

Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression (Journal article)

McRonald, F. E., Liloglou, T., Xinarianos, G., Hill, L., Rowbottom, L., Langan, J. E., . . . Risk, J. M. (2006). Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression. HUMAN MOLECULAR GENETICS, 15(8), 1271-1277. doi:10.1093/hmg/ddl042

DOI: 10.1093/hmg/ddl042

Promoter methylation of P16, RAR beta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing (Journal article)

Shaw, R. J., Liloglou, T., Rogers, S. N., Brown, J. S., Vaughan, E. D., Lowe, D., . . . Risk, J. M. (2006). Promoter methylation of P16, RAR beta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing. BRITISH JOURNAL OF CANCER, 94(4), 561-568. doi:10.1038/sj.bjc.6602972

DOI: 10.1038/sj.bjc.6602972

Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer (Journal article)

Cassidy, A., Myles, J. P., Liloglou, T., Duffy, S. W., & Field, J. K. (2006). Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY, 28(5), 1295-1301. Retrieved from http://gateway.webofknowledge.com/

Down-regulation of the KIP family members p27 KIP1 and p57 KIP2 by SKP2 and the role of methylation in p57KIP2 (Journal article)

Pateras, I. S., Kotsinas, A., Liloglou, T., Nikolaidis, G., Foukas, P., Koutsami, M., . . . Gorgoulis, V. G. (2006). Down-regulation of the KIP family members p27 KIP1 and p57 KIP2 by SKP2 and the role of methylation in p57KIP2. Int J Cancer.

Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: a novel approach using real-time PCR with melting curve analysis in histopathologic material. (Journal article)

Vageli, D., Daniil, Z., Dahabreh, J., Karagianni, E., Liloglou, T., Koukoulis, G., & Gourgoulianis, K. (2006). Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: a novel approach using real-time PCR with melting curve analysis in histopathologic material.. Oncology reports, 15(3), 557-564.

2005

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry (Journal article)

Ehrich, M., Nelson, M. R., Stanssens, P., Zabeau, M., Liloglou, T., Xinarianos, G., . . . van den Boom, D. (2005). Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(44), 15785-15790. doi:10.1073/pnas.0507816102

DOI: 10.1073/pnas.0507816102

Abnormal CYGB expression and hypermethylation in non-small cell lung cancer (Journal article)

Liloglou, T., McRonald, F., Xinarianos, G., Bowers, N., Risk, J., & Field, J. (2005). Abnormal CYGB expression and hypermethylation in non-small cell lung cancer. LUNG CANCER, 49, S134. doi:10.1016/S0169-5002(05)80572-0

DOI: 10.1016/S0169-5002(05)80572-0

Colorectal adenomas with a low frequency of ki-ras mutations: a sample from a population with a low mortality rate from colorectal cancer. (Journal article)

Kornaros, S., Liloglou, T., Politou, M., & Elemenoglou, I. (2005). Colorectal adenomas with a low frequency of ki-ras mutations: a sample from a population with a low mortality rate from colorectal cancer.. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 7(4), 323-326. doi:10.1111/j.1463-1318.2005.00809.x

DOI: 10.1111/j.1463-1318.2005.00809.x

Checkpoint activation identifies genetic damage in precancerous lesions (Journal article)

Gorgoulis, V. G., Vassiliou, L. F., Venere, M., DiTullio, R. A., Yoneta, A., Herlyn, M., . . . Kletsas, D. (2005). Checkpoint activation identifies genetic damage in precancerous lesions. Cancer Biology and Therapy, 4(5).

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. (Journal article)

Gorgoulis, V. G., Vassiliou, L. -V. F., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Halazonetis, T. D. (2005). Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.. Nature, 434(7035), 907-913. doi:10.1038/nature03485

DOI: 10.1038/nature03485

Methylation discriminators in NSCLC identified by a microarray based approach (Journal article)

Field, J. K., Liloglou, T., Warrak, S., Burger, M., Becker, E., Berlin, K., . . . Maier, S. (2005). Methylation discriminators in NSCLC identified by a microarray based approach. INTERNATIONAL JOURNAL OF ONCOLOGY, 27(1), 105-111. Retrieved from http://gateway.webofknowledge.com/

2004

Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas. (Journal article)

Gorgoulis, V. G., Liloglou, T., Sigala, F., Korkolis, D., Yannoukakos, D., Papalambros, E., . . . Kotsinas, A. (2004). Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas.. Mutation research, 556(1-2), 143-150. doi:10.1016/j.mrfmmm.2004.07.008

DOI: 10.1016/j.mrfmmm.2004.07.008

METH-2 silencing and promoter hypermethylation in NSCLC (Journal article)

Dunn, J. R., Panutsopulos, D., Shaw, M. W., Heighway, J., Dormer, R., Salmo, E. N., . . . Liloglou, T. (2004). METH-2 silencing and promoter hypermethylation in NSCLC. BRITISH JOURNAL OF CANCER, 91(6), 1149-1154. doi:10.1038/sj.bjc.6602107

DOI: 10.1038/sj.bjc.6602107

Glycine-extended gastrin promotes the growth of lung cancer (Journal article)

Koh, T. J., Field, J. K., Varro, A., Liloglou, T., Fielding, P., Cui, G. L., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. CANCER RESEARCH, 64(1), 196-201. doi:10.1158/0008-5472.CAN-03-2112

DOI: 10.1158/0008-5472.CAN-03-2112

Glycine-extended gastrin promotes the growth of lung cancer (Journal article)

Koh, T. J., Field, J. K., Varro, A., Liloglou, T., Fielding, P., Cui, G. L., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. Cancer Research, 64(1), 196-201. Retrieved from http://cancerres.aacrjournals.org/cgi/reprint/64/1/196

Glycine-extended gastrin promotes the growth of lung cancer (Journal article)

Koh, T. J., Field, J. K., Varro, A., Liloglou, L., Fielding, P., Cui, G., . . . Wang, T. C. (2004). Glycine-extended gastrin promotes the growth of lung cancer. Cancer Research, 64(1), 196-201. doi:10.1158/0008-5472.CAN-03-2112

DOI: 10.1158/0008-5472.CAN-03-2112

2003

Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin. (Journal article)

Saridaki, Z., Liloglou, T., Zafiropoulos, A., Koumantaki, E., Zoras, O., & Spandidos, D. A. (2003). Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin.. The British journal of dermatology, 148(4), 638-648. doi:10.1046/j.1365-2133.2003.05230.x

DOI: 10.1046/j.1365-2133.2003.05230.x

Absence of mutations in the VHL gene but frequent loss of heterozygosity at 3p25-26 in non-small cell lung carcinomas (Journal article)

Miyakis, S., Liloglou, T., Kearney, S., Xinarianos, G., Spandidos, D. A., & Field, J. K. (2003). Absence of mutations in the VHL gene but frequent loss of heterozygosity at 3p25-26 in non-small cell lung carcinomas. LUNG CANCER, 39(3), 273-277. doi:10.1016/S0169-5002(02)00506-8

DOI: 10.1016/S0169-5002(02)00506-8

Allelic imbalance at the DNA mismatch repair loci, hMSH2, hMLH1, hPMS1, hPMS2 and hMSH3, in squamous cell carcinoma of the head and neck (Journal article)

Nunn, J., Nagini, S., Risk, J. M., Prime, W., Maloney, P., Liloglou, T., . . . Field, J. K. (2003). Allelic imbalance at the DNA mismatch repair loci, hMSH2, hMLH1, hPMS1, hPMS2 and hMSH3, in squamous cell carcinoma of the head and neck. ORAL ONCOLOGY, 39(2), 115-129. doi:10.1016/S1368-8375(02)00028-3

DOI: 10.1016/S1368-8375(02)00028-3

Fluorescent microsatellite analysis in bronchial lavage as a potential diagnostic tool for lung cancer. (Journal article)

Field, J. K., & Liloglou, T. (2003). Fluorescent microsatellite analysis in bronchial lavage as a potential diagnostic tool for lung cancer.. Methods in molecular medicine, 75, 251-262. doi:10.1385/1-59259-324-0:251

DOI: 10.1385/1-59259-324-0:251

In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree (Journal article)

Sikkink, S. K., Liloglou, T., Maloney, P., Gosney, J. R., & Field, J. K. (2003). In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree. INTERNATIONAL JOURNAL OF ONCOLOGY, 22(3), 589-595. Retrieved from http://gateway.webofknowledge.com/

Method and nucleic acids for the analysis of a lung cell proliferative disorder (Patent)

Burger, M., Field, J. K., Genc, B. L., Liloglou, T., Lipscher, E., Maier, S., . . . Epigenomics AG. (2003). Method and nucleic acids for the analysis of a lung cell proliferative disorder.

Microsatellite analysis in bronchial lavage and sputum as a diagnostic tool of lung cancer (Book)

Field, J. K., & Liloglou, T. (2003). Microsatellite analysis in bronchial lavage and sputum as a diagnostic tool of lung cancer (Vol. 2). B. Driscol (Ed.), NY: Humana Press.

2002

p53 status correlates with the differential expression of the DNA mismatch repair protein MSH2 in non-small cell lung carcinoma (Journal article)

Xinarianos, G., Liloglou, T., Prime, W., Sourvinos, G., Karachristos, A., Gosney, J. R., . . . Field, J. K. (2002). p53 status correlates with the differential expression of the DNA mismatch repair protein MSH2 in non-small cell lung carcinoma. INTERNATIONAL JOURNAL OF CANCER, 101(3), 248-252. doi:10.1002/ijc.10598

DOI: 10.1002/ijc.10598

A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer (Journal article)

Liloglou, T., Walters, M., Maloney, P., Youngson, J., & Field, J. K. (2002). A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. LUNG CANCER, 37(2), 143-146. doi:10.1016/S0169-5002(02)00078-8

DOI: 10.1016/S0169-5002(02)00078-8

Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps (Journal article)

Langan, J. E., Rowbottom, L., Liloglou, T., Field, J. K., & Risk, J. M. (2002). Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps. BIOTECHNIQUES, 33(2), 276-+. doi:10.2144/02332bm04

DOI: 10.2144/02332bm04

2001

Loss of heterozygosity on chromosomes 3, 9, 13 and 17, including the retinoblastoma locus, in uveal melanoma (Journal article)

Scholes, A. G. M., Liloglou, T., Maloney, P., Hagan, S., Nunn, J., Hiscott, P., . . . Field, J. K. (2001). Loss of heterozygosity on chromosomes 3, 9, 13 and 17, including the retinoblastoma locus, in uveal melanoma. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 42(11), 2472-2477. Retrieved from http://gateway.webofknowledge.com/

Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas (Journal article)

Kotsinas, A., Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Kokotas, S., Liloglou, T., . . . Kittas, C. (2001). Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas. CANCER GENETICS AND CYTOGENETICS, 126(2), 147-154. doi:10.1016/S0165-4608(00)00407-6

DOI: 10.1016/S0165-4608(00)00407-6

Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer (Journal article)

Sourvinos, G., Miyakis, S., Liloglou, T. L., Field, J. K., & Spandidos, D. A. (2001). Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer. TUMOR BIOLOGY, 22(3), 131-136. doi:10.1159/000050607

DOI: 10.1159/000050607

Cancer-specific genomic instability in bronchial lavage: A molecular tool for lung cancer detection (Journal article)

Liloglou, T., Maloney, P., Xinarianos, G., Hulbert, M., Walshaw, M. J., Gosney, J. R., . . . Field, J. K. (2001). Cancer-specific genomic instability in bronchial lavage: A molecular tool for lung cancer detection. CANCER RESEARCH, 61(4), 1624-1628. Retrieved from http://gateway.webofknowledge.com/

Deregulated expression of c-mos in non-small cell lung carcinomas: Relationship with p53 status, genomic instability, and tumor kinetics (Journal article)

Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Liloglou, T., Kokotas, S., Kastrinakis, N., . . . Field, J. K. (2001). Deregulated expression of c-mos in non-small cell lung carcinomas: Relationship with p53 status, genomic instability, and tumor kinetics. CANCER RESEARCH, 61(2), 538-549. Retrieved from http://gateway.webofknowledge.com/

A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene (Journal article)

Kotsinas, A., Gorgoulis, V. G., Zacharatos, P., Liloglou, T., Leonardou, P., Brami, J., . . . Kittas, C. (2001). A new rare allele at the CGG repeat polymorphism in the first intron of human c-H-ras gene. IN VIVO, 15(1), 105-108. Retrieved from http://gateway.webofknowledge.com/

Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs) (Journal article)

Garinis, G. A., Gorgoulis, V. G., Mariatos, G., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2001). Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs). JOURNAL OF PATHOLOGY, 193(1), 55-65. doi:3.0.CO;2-#">10.1002/1096-9896(2000)9999:9999<::AID-PATH731>3.0.CO;2-#

DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH731>3.0.CO;2-#

Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs). (Journal article)

Garinis, G. A., Gorgoulis, V. G., Mariatos, G., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2001). Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs).. The Journal of pathology, 193(1), 55-65. doi:10.1002/1096-9896(2000)9999:9999<::aid-path731>3.0.co;2-#

DOI: 10.1002/1096-9896(2000)9999:9999<::aid-path731>3.0.co;2-#

Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma (Journal article)

Scholes, A. G., Liloglou, T., Maloney, P., Hagan, S., Nunn, J., Hiscott, P., . . . Field, J. K. (2001). Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma. Invest Ophthalmol Vis Sci, 42(11), 2472-2477.

2000

K-ras point mutation detection in lung cancer: Comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification (Journal article)

Clayton, S. J., Scott, F. M., Walker, J., Callaghan, K., Haque, K., Liloglou, T., . . . Fox, J. C. (2000). K-ras point mutation detection in lung cancer: Comparison of two approaches to somatic mutation detection using ARMS allele-specific amplification. CLINICAL CHEMISTRY, 46(12), 1929-1938. Retrieved from http://gateway.webofknowledge.com/

Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma (Journal article)

Gorgoulis, V. G., Kotsinas, A., Zacharatos, P., Mariatos, G., Liloglou, T., Tsoli, E., . . . Kittas, C. (2000). Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma. CANCER, 89(9), 1933-1945. doi:3.3.CO;2-4">10.1002/1097-0142(20001101)89:9<1933::AID-CNCR9>3.3.CO;2-4

DOI: 10.1002/1097-0142(20001101)89:9<1933::AID-CNCR9>3.3.CO;2-4

The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas (Journal article)

Miyakis, S., Sourvinos, G., Liloglou, T. L., Stathopoulos, G. P., Field, J. K., & Spandidos, D. A. (2000). The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas. INTERNATIONAL JOURNAL OF CANCER, 88(3), 503-505. doi:3.0.CO;2-9">10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9

DOI: 10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9

The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas (Journal article)

Miyakis, S., Sourvinos, G., Liloglou, T. L., Stathopoulos, G. P., Field, J. K., & Spandidos, D. A. (2000). The Von Hippel-Lindau (VHL) tumor-suppressor gene is not mutated in sporadic human colon adenocarcinomas. International Journal of Cancer, 88(3), 503-505. doi:3.0.CO;2-9">10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9

DOI: 10.1002/1097-0215(20001101)88:3<503::AID-IJC28>3.0.CO;2-9

c-mos immunoreactivity is an indicator of good prognosis in lung cancer (Journal article)

Athanasiou, A., Gorgoulis, V. G., Zacharatos, P., Mariatos, G., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2000). c-mos immunoreactivity is an indicator of good prognosis in lung cancer. HISTOPATHOLOGY, 37(1), 45-54. doi:10.1046/j.1365-2559.2000.00898.x

DOI: 10.1046/j.1365-2559.2000.00898.x

hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas (Journal article)

Xinarianos, G., Liloglou, T., Prime, W., Maloney, P., Callaghan, J., Fielding, P., . . . Field, J. K. (2000). hMLH1 and hMSH2 expression correlates with allelic imbalance on chromosome 3p in non-small cell lung carcinomas. CANCER RESEARCH, 60(15), 4216-4221. Retrieved from http://gateway.webofknowledge.com/

Allelic imbalance at the 5q14 locus is associated with decreased apoptotic rate in non-small cell lung carcinomas (NSCLCs). Possible synergistic effect with p53 gene alterations on apoptosis (Journal article)

Gorgoulis, V. G., Mariatos, G., Manolis, E. N., Zacharatos, P., Kotsinas, A., Liloglou, T., . . . Kittas, C. (2000). Allelic imbalance at the 5q14 locus is associated with decreased apoptotic rate in non-small cell lung carcinomas (NSCLCs). Possible synergistic effect with p53 gene alterations on apoptosis. LUNG CANCER, 28(3), 211-224. doi:10.1016/S0169-5002(99)00137-3

DOI: 10.1016/S0169-5002(99)00137-3

Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease (Journal article)

Xinarianos, G., Scott, F. M., Liloglou, T., Prime, W., Turnbull, L., Walshaw, M., & Field, J. K. (2000). Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease. LUNG CANCER, 28(1), 37-42. doi:10.1016/S0169-5002(99)00111-7

DOI: 10.1016/S0169-5002(99)00111-7

Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status (Journal article)

Mariatos, G., Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Vogiatzi, T., Rassidakis, G., . . . Kittas, C. (2000). Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status. INTERNATIONAL JOURNAL OF CANCER, 89(2), 133-141. doi:3.0.CO;2-C">10.1002/(SICI)1097-0215(20000320)89:2<133::AID-IJC6>3.0.CO;2-C

DOI: 10.1002/(SICI)1097-0215(20000320)89:2<133::AID-IJC6>3.0.CO;2-C

Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs) (Journal article)

Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Mariatos, G., Liloglou, T., Vogiatzi, T., . . . Kittas, C. (2000). Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs). MOLECULAR MEDICINE, 6(3), 208-237. doi:10.1007/BF03402115

DOI: 10.1007/BF03402115

Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status (Journal article)

Mariatos, G., Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Vogiatzi, T., Rassidakis, G., . . . Kittas, C. (2000). Expression of p16(INK4A) and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status. International Journal of Cancer, 86(3), 133-141. doi:3.0.co;2-c">10.1002/(sici)1097-0215(20000320)89:2<133::aid-ijc6>3.0.co;2-c

DOI: 10.1002/(sici)1097-0215(20000320)89:2<133::aid-ijc6>3.0.co;2-c

High frequency of loss of heterozygosity on chromosome region 9p21-p22 but lack of p16INK4a/p19ARF mutations in greek patients with basal cell carcinoma of the skin. (Journal article)

Saridaki, Z., Koumantaki, E., Liloglou, T., Sourvinos, G., Papadopoulos, O., Zoras, O., & Spandidos, D. A. (2000). High frequency of loss of heterozygosity on chromosome region 9p21-p22 but lack of p16INK4a/p19ARF mutations in greek patients with basal cell carcinoma of the skin.. The Journal of investigative dermatology, 115(4), 719-725. doi:10.1046/j.1523-1747.2000.00098.x

DOI: 10.1046/j.1523-1747.2000.00098.x

Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment (Journal article)

Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (2000). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. ANTICANCER RESEARCH, 19(1A), 579-587. Retrieved from http://www.ncbi.nlm.nih.gov/

Sensitivity and limitations of high throughput fluorescent microsatellite analysis for the detection of allelic imbalance: Application in lung tumors (Journal article)

Liloglou, T., Maloney, P., Xinarianos, G., Fear, S., & Field, J. K. (2000). Sensitivity and limitations of high throughput fluorescent microsatellite analysis for the detection of allelic imbalance: Application in lung tumors. INTERNATIONAL JOURNAL OF ONCOLOGY, 16(1), 5-14. Retrieved from http://gateway.webofknowledge.com/

1999

Genetic alterations is bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer (Journal article)

Field, J. K., Liloglou, T., Xinarianos, G., Prime, W., Fielding, P., Walshaw, M. J., & Turnbull, L. (1999). Genetic alterations is bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer. CANCER RESEARCH, 59(11), 2690-2695. Retrieved from http://gateway.webofknowledge.com/

Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1. (Journal article)

Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (1999). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.. Anticancer research, 19(1A), 579-587.

Fractional allele loss indicates distinct genetic populations in the development of squamous cell carcinoma of the head and neck (SCCHN) (Journal article)

Nunn, J., Scholes, A. G. M., Liloglou, T., Nagini, S., Jones, A. S., Vaughan, E. D., . . . Field, J. K. (1999). Fractional allele loss indicates distinct genetic populations in the development of squamous cell carcinoma of the head and neck (SCCHN). CARCINOGENESIS, 20(12), 2219-2228. doi:10.1093/carcin/20.12.2219

DOI: 10.1093/carcin/20.12.2219

Microsatellite instability and p53 mutations in hepatocellular carcinoma. (Journal article)

Karachristos, A., Liloglou, T., Field, J. K., Deligiorgi, E., Kouskouni, E., & Spandidos, D. A. (1999). Microsatellite instability and p53 mutations in hepatocellular carcinoma.. Molecular cell biology research communications : MCBRC, 2(3), 155-161. doi:10.1006/mcbr.1999.0170

DOI: 10.1006/mcbr.1999.0170

Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. (Journal article)

Zacharatos, P. V., Gorgoulis, V. G., Kotsinas, A., Manolis, E. N., Liloglou, T., Rassidakis, A. N., . . . Kittas, C. (1999). Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment.. Anticancer Res, 19(1A), 579-587.

Telomerase activity in non-small cell lung carcinomas correlates with smoking status (Journal article)

Xinarianos, G., Scott, F. M., Liloglou, T., Prime, W., Callaghan, J., Gosney, J. R., & Field, J. K. (1999). Telomerase activity in non-small cell lung carcinomas correlates with smoking status. INTERNATIONAL JOURNAL OF ONCOLOGY, 15(5), 961-965. Retrieved from http://gateway.webofknowledge.com/

1998

Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas - Relationship with p53 and MDM2 protein expression (Journal article)

Gorgoulis, V. G., Zacharatos, P., Kotsinas, A., Liloglou, T., Kyroudi, A., Veslemes, M., . . . Kittas, C. (1998). Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas - Relationship with p53 and MDM2 protein expression. AMERICAN JOURNAL OF PATHOLOGY, 153(6), 1749-1765. doi:10.1016/S0002-9440(10)65690-8

DOI: 10.1016/S0002-9440(10)65690-8

Microsatellite instability and loss of heterozygosity in bronchial lavage specimens (Journal article)

Liloglou, T., Xinarianos, G., Prime, W., Walshaw, M., Turnbull, L., & Field, J. K. (1998). Microsatellite instability and loss of heterozygosity in bronchial lavage specimens. BRITISH JOURNAL OF CANCER, 78(2), 147-148. Retrieved from http://gateway.webofknowledge.com/

Molecular pathological mechanisms in NSCLC and the assessment of individuals with a high risk of developing lung cancer (Book)

Field, J. K., Ross, H., Liloglou, T., Scott, F., Prime, W., Gosney, J. R., . . . Donnelly, R. J. (1998). Molecular pathological mechanisms in NSCLC and the assessment of individuals with a high risk of developing lung cancer. Retrieved from http://gateway.webofknowledge.com/

Smoking correlates with the presence of p53 mutations in squamous cell carcinomas of the head and neck (SCCHN) (Conference Paper)

Liloglou., Scholes., Spandidos., Jones., Vaughan., & Field. (1998). Smoking correlates with the presence of p53 mutations in squamous cell carcinomas of the head and neck (SCCHN). In Clinical Otolaryngology and Allied Sciences Vol. 23 (pp. 268-269). Wiley. doi:10.1046/j.1365-2273.1998.0135m.x

DOI: 10.1046/j.1365-2273.1998.0135m.x

The Knights of the Round Table hypothesis of tumour suppressor gene function - noble sacrifice or sexual dalliance: Genes, including p53, BRCA1/2 and RB have evolved by horizontal and vertical transmission of mating factor genes and are involved in gametogenesis, implantation, development and tumourigenesis (Journal article)

Gosden, C. M., Liloglou, T., Nunn, J., Gardener, D., Nickson, P., Crampton, J. M., & Field, J. K. (1998). The Knights of the Round Table hypothesis of tumour suppressor gene function - noble sacrifice or sexual dalliance: Genes, including p53, BRCA1/2 and RB have evolved by horizontal and vertical transmission of mating factor genes and are involved in gametogenesis, implantation, development and tumourigenesis. INTERNATIONAL JOURNAL OF ONCOLOGY, 12(1), 5-35. Retrieved from http://gateway.webofknowledge.com/

1997

p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability (Journal article)

Liloglou, T., Scholes, A. G. M., Spandidos, D. A., Vaughan, E. D., Jones, A. S., & Field, J. K. (1997). p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability. CANCER RESEARCH, 57(18), 4070-4074. Retrieved from http://gateway.webofknowledge.com/

p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck (Journal article)

Scholes, A. G. M., Liloglou, T., Snijders, P. J. F., Hart, C. A., Jones, A. S., Woolgar, J. A., . . . Field, J. K. (1997). p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck. International Journal of Cancer, 71(5), 796-799. doi:3.0.CO;2-6">10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6

DOI: 10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6

p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck (Journal article)

Scholes, A. G. M., Liloglou, T., Snijders, P. J. F., Hart, C. A., Jones, A. S., Woolgar, J. A., . . . Field, J. K. (1997). p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck. INTERNATIONAL JOURNAL OF CANCER, 71(5), 796-799. doi:3.0.CO;2-6">10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6

DOI: 10.1002/(SICI)1097-0215(19970529)71:5<796::AID-IJC17>3.0.CO;2-6

Codon 12 ras mutations in patients with myelodysplastic syndrome: incidence and prognostic value. (Journal article)

Constantinidou, M., Chalevelakis, G., Economopoulos, T., Koffa, M., Liloglou, T., Anastassiou, C., . . . Raptis, S. (1997). Codon 12 ras mutations in patients with myelodysplastic syndrome: incidence and prognostic value.. Annals of hematology, 74(1), 11-14. doi:10.1007/s002770050248

DOI: 10.1007/s002770050248

N-ras and K-ras genes point mutations in childhood lymphomas (Journal article)

Koffa, M., Kalmanti, M., Sakalidou, A., Kanavaros, P., Liloglou, T., & Spandidos, D. A. (1997). N-ras and K-ras genes point mutations in childhood lymphomas. Archive of Oncology, 5(1), 5-7.

p53 gene aberrations in non-small-cell lung carcinomas from a smoking population (Journal article)

Liloglou, T., Ross, H., Prime, W., Donnelly, R. J., Spandidos, D. A., Gosney, J. R., & Field, J. K. (1997). p53 gene aberrations in non-small-cell lung carcinomas from a smoking population. BRITISH JOURNAL OF CANCER, 75(8), 1119-1124. doi:10.1038/bjc.1997.193

DOI: 10.1038/bjc.1997.193

1996

Allelotype of non-small cell lung cancer (Journal article)

Neville, E. M., Stewart, M. P., Swift, A., Liloglou, T., Ross, H., Gosney, J. R., . . . Field, J. K. (1996). Allelotype of non-small cell lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY, 9(3), 533-539. Retrieved from http://gateway.webofknowledge.com/

Fractional allele loss data indicate distinct genetic populations in the development of non-small-cell lung cancer (Journal article)

Field, J. K., Neville, E. M., Stewart, M. P., Swift, A., Liloglou, T., Risk, J. M., . . . Donnelly, R. J. (1996). Fractional allele loss data indicate distinct genetic populations in the development of non-small-cell lung cancer. BRITISH JOURNAL OF CANCER, 74(12), 1968-1974. doi:10.1038/bjc.1996.661

DOI: 10.1038/bjc.1996.661

Polymorphisms in the promoter region of the WAF1/CIP1 gene (Journal article)

Liloglou, T., Risk, J. M., & Field, J. K. (1996). Polymorphisms in the promoter region of the WAF1/CIP1 gene. INTERNATIONAL JOURNAL OF ONCOLOGY, 9(3), 559-562. Retrieved from http://gateway.webofknowledge.com/

1994

DETECTION OF HUMAN CYTOMEGALOVIRUS AND EPSTEIN-BARR-VIRUS BY THE POLYMERASE CHAIN-REACTION IN PATIENTS WITH BETA-THALASSEMIA (Journal article)

ERGAZAKI, M., XINARIANOS, G., GIANNOUDIS, A., KOFFA, M., LILOGLOU, T., KATTAMIS, C., & SPANDIDOS, D. A. (1994). DETECTION OF HUMAN CYTOMEGALOVIRUS AND EPSTEIN-BARR-VIRUS BY THE POLYMERASE CHAIN-REACTION IN PATIENTS WITH BETA-THALASSEMIA. ONCOLOGY REPORTS, 1(4), 813-816. Retrieved from http://gateway.webofknowledge.com/

DETECTION OF HUMAN CYTOMEGALOVIRUS BY THE POLYMERASE CHAIN-REACTION IN IMMUNOSUPPRESSED AND IMMUNOCOMPROMISED PATIENTS (Journal article)

ERGAZAKI, M., XINARIANOS, G., KOFFA, M., LILOGLOU, T., & SPANDIDOS, D. A. (n.d.). DETECTION OF HUMAN CYTOMEGALOVIRUS BY THE POLYMERASE CHAIN-REACTION IN IMMUNOSUPPRESSED AND IMMUNOCOMPROMISED PATIENTS. Oncology Reports. doi:10.3892/or.1.4.805

DOI: 10.3892/or.1.4.805

DETECTION OF THE EPSTEIN-BARR-VIRUS BY THE POLYMERASE CHAIN-REACTION IN IMMUNOSUPPRESSED AND IMMUNOCOMPROMISED PATIENTS (Journal article)

LILOGLOU, T., GIANNOUDIS, A., ERGAZAKI, M., KOFFA, M., & SPANDIDOS, D. A. (1994). DETECTION OF THE EPSTEIN-BARR-VIRUS BY THE POLYMERASE CHAIN-REACTION IN IMMUNOSUPPRESSED AND IMMUNOCOMPROMISED PATIENTS. ONCOLOGY REPORTS, 1(4), 809-811. Retrieved from http://gateway.webofknowledge.com/

INDUCIBLE H-RAS GENE-EXPRESSION CONTROLLED BY AN ALLOSTERICALLY REGULATED TRANSACTIVATOR (Journal article)

LILOGLOU, T., KOTSINAS, A., & SPANDIDOS, D. A. (n.d.). INDUCIBLE H-RAS GENE-EXPRESSION CONTROLLED BY AN ALLOSTERICALLY REGULATED TRANSACTIVATOR. Oncology Reports. doi:10.3892/or.1.5.889

DOI: 10.3892/or.1.5.889

T24 H-RAS GENE-EXPRESSION INCREASES THE ACTIVITY OF PHOSPHOGLYCERATE KINASE, ENOLASE AND PYRUVATE-KINASE AND DECREASES THE ACTIVITY OF ADENOSINE-DEAMINASE IN FIBROBLAST CELLS (Journal article)

LILOGLOU, T., TEGOS, C., & SPANDIDOS, D. A. (n.d.). T24 H-RAS GENE-EXPRESSION INCREASES THE ACTIVITY OF PHOSPHOGLYCERATE KINASE, ENOLASE AND PYRUVATE-KINASE AND DECREASES THE ACTIVITY OF ADENOSINE-DEAMINASE IN FIBROBLAST CELLS. Oncology Reports. doi:10.3892/or.1.6.1193

DOI: 10.3892/or.1.6.1193

1993

DETECTION OF HEPATITIS-B VIRUS-DNA AND MUTATIONS IN K-RAS AND P53 GENES IN HUMAN HEPATOCELLULAR CARCINOMAS (Journal article)

NIKOLAIDOU, A., LILOGLOU, T., MALLIRI, A., ERGAZAKI, M., TINIAKOS, G., TINIAKOS, D., & SPANDIDOS, D. A. (n.d.). DETECTION OF HEPATITIS-B VIRUS-DNA AND MUTATIONS IN K-RAS AND P53 GENES IN HUMAN HEPATOCELLULAR CARCINOMAS. International Journal of Oncology. doi:10.3892/ijo.3.4.593

DOI: 10.3892/ijo.3.4.593

Detection of the cytomegalovirus by the polymerase chain reaction DNA amplification in a kidney transplanted patient (Journal article)

Ergazaki, M., Liloglou, T., Koffa, M., Kostakis, A., Haliassos, A., & Spandidos, D. A. (1993). Detection of the cytomegalovirus by the polymerase chain reaction DNA amplification in a kidney transplanted patient. In Vivo, 7(6A), 531-534.

Detection of the cytomegalovirus by the polymerase chain reaction DNA amplification in a kidney transplanted patient. (Journal article)

Ergazaki, M., Liloglou, T., Koffa, M., Kostakis, A., Haliassos, A., & Spandidos, D. A. (1993). Detection of the cytomegalovirus by the polymerase chain reaction DNA amplification in a kidney transplanted patient.. In vivo (Athens, Greece), 7(6A), 531-534.

PROGNOSTIC-SIGNIFICANCE OF ONCOGENES AND TUMOR-SUPPRESSOR GENES IN HUMAN MALIGNANCY (Journal article)

SPANDIDOS, D. A., LILOGLOU, T., & FIELD, J. K. (1993). PROGNOSTIC-SIGNIFICANCE OF ONCOGENES AND TUMOR-SUPPRESSOR GENES IN HUMAN MALIGNANCY. STEM CELLS, 11(3), 194-198. doi:10.1002/stem.5530110305

DOI: 10.1002/stem.5530110305

RAS GENE ACTIVATION IN HUMAN SMALL INTESTINAL TUMORS (Journal article)

SPANDIDOS, D. A., LILOGLOU, T., ARVANITIS, D., & GOURTSOYIANNIS, N. C. (n.d.). RAS GENE ACTIVATION IN HUMAN SMALL INTESTINAL TUMORS. International Journal of Oncology. doi:10.3892/ijo.2.4.513

DOI: 10.3892/ijo.2.4.513

The Polymerase Chain Reaction in medical applications (Journal article)

Haliassos, A., Liloglou, T., Ergazaki, M., & Spandidos, D. A. (1993). The Polymerase Chain Reaction in medical applications. Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 7(1), 7-16.

1992

Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer (Journal article)

Knight, L. J., Burrage, J., Bujac, S. R., Haggerty, C., Graham, A., Gibson, N. J., . . . Liloglou, T. (2009). Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY, 34(2), 465-471. doi:10.3892/ijo_00000171

DOI: 10.3892/ijo_00000171