Photo of Miss Nichola Rockliffe

Miss Nichola Rockliffe BSc genetics

Research Technician Biochemistry & Systems Biology

Publications

2018

Increased socially mediated plasticity in gene expression accompanies rapid adaptive evolution (Journal article)

Pascoal, S., Liu, X., Fang, Y., Paterson, S., Ritchie, M. G., Rockliffe, N., . . . Bailey, N. W. (2018). Increased socially mediated plasticity in gene expression accompanies rapid adaptive evolution. Ecology Letters, 21(4), 546-556. doi:10.1111/ele.12920

DOI: 10.1111/ele.12920

2017

Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus (Journal article)

Liu, X., Speranza, E., Muñoz-Fontela, C., Haldenby, S., Rickett, N., Garcia-Dorival, I., . . . Hiscox, J. (2017). Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus. Genome Biology, 18. doi:10.1186/s13059-016-1137-3

DOI: 10.1186/s13059-016-1137-3

2016

Rapid evolution and gene expression: a rapidly evolving Mendelian trait that silences field crickets has widespread effects on mRNA and protein expression (Journal article)

Pascoal, S., Liu, X., Ly, T., Fang, Y., Rockliffe, N., Paterson, S., . . . Bailey, N. W. (2016). Rapid evolution and gene expression: a rapidly evolving Mendelian trait that silences field crickets has widespread effects on mRNA and protein expression. JOURNAL OF EVOLUTIONARY BIOLOGY, 29(6), 1234-1246. doi:10.1111/jeb.12865

DOI: 10.1111/jeb.12865

2015

Type of in vitro cultivation influences cytoadhesion, knob structure, protein localization and transcriptome profile of Plasmodium falciparum (Journal article)

Tilly, A. -K., Thiede, J., Metwally, N., Lubiana, P., Bachmann, A., Roeder, T., . . . Bruchhaus, I. (2015). Type of in vitro cultivation influences cytoadhesion, knob structure, protein localization and transcriptome profile of Plasmodium falciparum. SCIENTIFIC REPORTS, 5. doi:10.1038/srep16766

DOI: 10.1038/srep16766

2012

Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak (Journal article)

Melarangi, T., Zhuang, J., Lin, K., Rockliffe, N., Bosanquet, A. G., Oates, M., . . . Pettitt, A. R. (2012). Glucocorticoid resistance in chronic lymphocytic leukaemia is associated with a failure of upregulated Bim/Bcl-2 complexes to activate Bax and Bak. CELL DEATH & DISEASE, 3. doi:10.1038/cddis.2012.102

DOI: 10.1038/cddis.2012.102

2008

Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells (Journal article)

Lin, K., Rockliffe, N., Johnson, G. G., Sherrington, P. D., & Pettitt, A. R. (2008). Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells. Oncogene, 27(17), 2445-2455. doi:10.1038/sj.onc.1210893

DOI: 10.1038/sj.onc.1210893

2006

Differential mechanisms of glutamate receptor regulation of SynGAP in cortical neurones (Journal article)

Rockliffe, N., & Gawler, D. (2006). Differential mechanisms of glutamate receptor regulation of SynGAP in cortical neurones. FEBS Letters, 580(3), 831-838. doi:10.1016/j.febslet.2005.12.100

DOI: 10.1016/j.febslet.2005.12.100

2004

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin (Journal article)

Willshaw, A., Grant, K., Yan, J., Rockliffe, N., Ambavarapu, S., Burdyga, G., . . . Gawler, D. (2004). Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin. FEBS Letters, 559(1-3), 13-21. doi:10.1016/s0014-5793(03)01513-8

DOI: 10.1016/s0014-5793(03)01513-8