Dr John Fenwick

Molecular & Clinical Cancer Medicine

Publications

2021

Classification of tolerable/intolerable mucosal toxicity of head-and-neck radiotherapy schedules with a biomathematical model of cell dynamics (Journal article)

Pardo-Montero, J., Parga-Pazos, M., & Fenwick, J. D. (2021). Classification of tolerable/intolerable mucosal toxicity of head-and-neck radiotherapy schedules with a biomathematical model of cell dynamics. MEDICAL PHYSICS, 48(7), 4075-4084. doi:10.1002/mp.14834

DOI: 10.1002/mp.14834

Report of AAPM Task Group 155: Megavoltage photon beam dosimetry in small fields and non-equilibrium conditions. (Journal article)

Das, I. J., Francescon, P., Moran, J. M., Ahnesjö, A., Aspradakis, M. M., Cheng, C. -W., . . . Sauer, O. A. (2021). Report of AAPM Task Group 155: Megavoltage photon beam dosimetry in small fields and non-equilibrium conditions.. Medical physics. doi:10.1002/mp.15030

DOI: 10.1002/mp.15030

Cardiac-sparing radiotherapy for locally advanced non-small cell lung cancer (Journal article)

Turtle, L., Bhalla, N., Willett, A., Biggar, R., Leadbetter, J., Georgiou, G., . . . Fenwick, J. D. (2021). Cardiac-sparing radiotherapy for locally advanced non-small cell lung cancer. RADIATION ONCOLOGY, 16(1). doi:10.1186/s13014-021-01824-3

DOI: 10.1186/s13014-021-01824-3

2020

A mathematical model of dynamics of cell populations in squamous epithelium after irradiation (Journal article)

Parga-Pazos, M., Lopez Pouso, O., Fenwick, J. D., & Pardo-Montero, J. (n.d.). A mathematical model of dynamics of cell populations in squamous epithelium after irradiation. International Journal of Radiation Biology. doi:10.1080/09553002.2020.1787540

DOI: 10.1080/09553002.2020.1787540

Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic (Journal article)

Faivre-Finn, C., Fenwick, J. D., Franks, K. N., Harrow, S., Hatton, M. Q. F., Hiley, C., . . . Toy, E. (2020). Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic. CLINICAL ONCOLOGY, 32(8), 481-489. doi:10.1016/j.clon.2020.05.001

DOI: 10.1016/j.clon.2020.05.001

Density compensated diodes for small field dosimetry: comprehensive testing and implications for design. (Journal article)

Georgiou, G., Kumar, S., Wuerfel, J., Underwood, T. S. A., Thompson, J., Hill, M. A., . . . Fenwick, J. D. (2020). Density compensated diodes for small field dosimetry: comprehensive testing and implications for design.. Physics in medicine and biology. doi:10.1088/1361-6560/ab91d9

DOI: 10.1088/1361-6560/ab91d9

Radiotherapy to the Primary Tumour for Patients with Metastatic Prostate Cancer: Practice-Changing Results from STAMPEDE (Journal article)

Malik, Z. I., & Fenwick, J. D. (2020). Radiotherapy to the Primary Tumour for Patients with Metastatic Prostate Cancer: Practice-Changing Results from STAMPEDE. CLINICAL ONCOLOGY, 32(5), 327-329. doi:10.1016/j.clon.2019.12.010

DOI: 10.1016/j.clon.2019.12.010

Long-Term Results from the IDEAL-CRT Phase 1/2 Trial of Isotoxically Dose-Escalated Radiation Therapy and Concurrent Chemotherapy for Stage II/III Non-small Cell Lung Cancer (Journal article)

Fenwick, J. D., Landau, D. B., Baker, A. T., Bates, A. T., Eswar, C., Garcia-Alonso, A., . . . Counsell, N. (2020). Long-Term Results from the IDEAL-CRT Phase 1/2 Trial of Isotoxically Dose-Escalated Radiation Therapy and Concurrent Chemotherapy for Stage II/III Non-small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 106(4), 733-742. doi:10.1016/j.ijrobp.2019.11.397

DOI: 10.1016/j.ijrobp.2019.11.397

Chemoradiotherapy of locally-advanced non-small cell lung cancer: Analysis of radiation dose-response, chemotherapy and survival-limiting toxicity effects indicates a low alpha/beta ratio (Journal article)

Nix, M. G., Rowbottom, C. G., Vivekanandan, S., Hawkins, M. A., & Fenwick, J. D. (2020). Chemoradiotherapy of locally-advanced non-small cell lung cancer: Analysis of radiation dose-response, chemotherapy and survival-limiting toxicity effects indicates a low alpha/beta ratio. RADIOTHERAPY AND ONCOLOGY, 143, 58-65. doi:10.1016/j.radonc.2019.07.026

DOI: 10.1016/j.radonc.2019.07.026

2019

Development of a novel 3D immersive visualisation tool for manual image matching (Journal article)

Byrd, B., Warren, M., Fenwick, J., & Bridge, P. (2019). Development of a novel 3D immersive visualisation tool for manual image matching. Journal of Radiotherapy in Practice. doi:10.1017/S1460396919000219

DOI: 10.1017/S1460396919000219

Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma (Journal article)

McGowan, D. R., Skwarski, M., Bradley, K. M., Campo, L., Fenwick, J. D., Gleeson, F. V., . . . Higgins, G. S. (2019). Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma. EUROPEAN JOURNAL OF CANCER, 113, 87-95. doi:10.1016/j.ejca.2019.03.015

DOI: 10.1016/j.ejca.2019.03.015

Accelerated, Dose escalated, Sequential Chemoradiotherapy in Non-small-cell lung cancer (ADSCaN): a protocol for a randomised phase II study (Journal article)

Hatton, M. Q. F., Lawless, C. A., Faivre-Finn, C., Landau, D., Lester, J. F., Fenwick, J., . . . Paul, J. (2019). Accelerated, Dose escalated, Sequential Chemoradiotherapy in Non-small-cell lung cancer (ADSCaN): a protocol for a randomised phase II study. BMJ OPEN, 9(1). doi:10.1136/bmjopen-2017-019903

DOI: 10.1136/bmjopen-2017-019903

2018

Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer (Journal article)

Lord, S. R., Cheng, W. -C., Liu, D., Gaude, E., Haider, S., Metcalf, T., . . . Harris, A. L. (2018). Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer. CELL METABOLISM, 28(5), 679-688. doi:10.1016/j.cmet.2018.08.021

DOI: 10.1016/j.cmet.2018.08.021

Reply to comment on 'origins of the changing detector response in small megavoltage photon radiation fields' (Journal article)

Fenwick, J. D., Georgiou, G., Rowbottom, C. G., Underwood, T. S. A., & Kumar, S. (2018). Reply to comment on 'origins of the changing detector response in small megavoltage photon radiation fields'. PHYSICS IN MEDICINE AND BIOLOGY, 63(19). doi:10.1088/1361-6560/aae0e4

DOI: 10.1088/1361-6560/aae0e4

Whole tumor kinetics analysis of F-18-fluoromisonidazole dynamic PET scans of non-small cell lung cancer patients, and correlations with perfusion CT blood flow (Journal article)

McGowan, D. R., Skwarski, M., Papiez, B. W., Macpherson, R. E., Gleeson, F. V., Schnabel, J. A., . . . Fenwick, J. D. (2018). Whole tumor kinetics analysis of F-18-fluoromisonidazole dynamic PET scans of non-small cell lung cancer patients, and correlations with perfusion CT blood flow. EJNMMI RESEARCH, 8. doi:10.1186/s13550-018-0430-4

DOI: 10.1186/s13550-018-0430-4

Origins of the changing detector response in small megavoltage photon radiation fields (Journal article)

Fenwick, J. D., Georgiou, G., Rowbottom, C. G., Underwood, T. S. A., Kumar, S., & Nahum, A. E. (2018). Origins of the changing detector response in small megavoltage photon radiation fields. PHYSICS IN MEDICINE AND BIOLOGY, 63(12). doi:10.1088/1361-6560/aac478

DOI: 10.1088/1361-6560/aac478

4D-PET reconstruction using a spline-residue model with spatial and temporal roughness penalties (Journal article)

Ralli, G. P., Chappell, M. A., McGowan, D. R., Sharma, R. A., Higgins, G. S., & Fenwick, J. D. (2018). 4D-PET reconstruction using a spline-residue model with spatial and temporal roughness penalties. Physics in Medicine and Biology, 63(9). doi:10.1088/1361-6560/aabb62

DOI: 10.1088/1361-6560/aabb62

Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer (Journal article)

Conibear, J., Chia, B., Ngai, Y., Bates, A. T., Counsell, N., Patel, R., . . . Landau, D. (2018). Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer. BMJ OPEN, 8(4). doi:10.1136/bmjopen-2017-020690

DOI: 10.1136/bmjopen-2017-020690

2017

Clinical and Dosimetric Factors Impacting Radiation Pneumonitis in Isotoxically Dose-Escalated NSCLC (Conference Paper)

Vivekanandan, S., Landau, D. B., Counsell, N., Warren, D. R., Farrelly, L., Ngai, Y., . . . Fenwick, J. D. (2017). Clinical and Dosimetric Factors Impacting Radiation Pneumonitis in Isotoxically Dose-Escalated NSCLC. In INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Vol. 99 (pp. S153). doi:10.1016/j.ijrobp.2017.06.354

DOI: 10.1016/j.ijrobp.2017.06.354

F-18-fluoromisonidazole uptake in advanced stage non-small cell lung cancer: A voxel-by-voxel PET kinetics study (Journal article)

McGowan, D. R., Macpherson, R. E., Hackett, S. L., Liu, D., Gleeson, F. V., McKenna, W. G., . . . Fenwick, J. D. (2017). F-18-fluoromisonidazole uptake in advanced stage non-small cell lung cancer: A voxel-by-voxel PET kinetics study. MEDICAL PHYSICS, 44(9), 4665-4676. doi:10.1002/mp.12416

DOI: 10.1002/mp.12416

The Impact of Cardiac Radiation Dosimetry on Survival After Radiation Therapy for Non-Small Cell Lung Cancer (Journal article)

Vivekanandan, S., Landau, D. B., Counsell, N., Warren, D. R., Khwanda, A., Rosen, S. D., . . . Fenwick, J. D. (2017). The Impact of Cardiac Radiation Dosimetry on Survival After Radiation Therapy for Non-Small Cell Lung Cancer. International Journal of Radiation: Oncology - Biology - Physics, 99(1), 51-60. doi:10.1016/j.ijrobp.2017.04.026

DOI: 10.1016/j.ijrobp.2017.04.026

4D-PET RECONSTRUCTION OF DYNAMIC NON-SMALL CELL LUNG CANCER [18-F]-FMISO-PET DATA USING ADAPTIVE-KNOT CUBIC B-SPLINES (Conference Paper)

Ralli, G. P., McGowan, D. R., Chappell, M. A., Sharma, R. A., Higgins, G. S., Fenwick, J. D., & IEEE. (2017). 4D-PET RECONSTRUCTION OF DYNAMIC NON-SMALL CELL LUNG CANCER [18-F]-FMISO-PET DATA USING ADAPTIVE-KNOT CUBIC B-SPLINES. In 2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017) (pp. 1189-1192). Retrieved from http://gateway.webofknowledge.com/

ADSCaN: A Randomised Phase II study of Accelerated, Dose escalated, Sequential Chemo-radiotherapy in Non-Small Cell Lung Cancer (NSCLC) (Conference Paper)

Lawless, C. A., Landau, D. B., Faivre-Finn, C., Boyd, K., Lester, J. F., Fenwick, J., . . . Hatton, M. Q. (2017). ADSCaN: A Randomised Phase II study of Accelerated, Dose escalated, Sequential Chemo-radiotherapy in Non-Small Cell Lung Cancer (NSCLC). In LUNG CANCER Vol. 103 (pp. S80-S81). Retrieved from http://gateway.webofknowledge.com/

2016

Investigation into the optimal model for whole tumour and voxel FMISO kinetics analysis (Conference Paper)

McGowan, D. R., Macpherson, R. E., Hackett, S. L., Gleeson, F. V., Higgins, G. S., & Fenwick, J. D. (2016). Investigation into the optimal model for whole tumour and voxel FMISO kinetics analysis. In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Vol. 43 (pp. S26). Retrieved from http://gateway.webofknowledge.com/

IDEAL-CRT: A Phase 1/2 Trial of Isotoxic Dose-Escalated Radiation Therapy and Concurrent Chemotherapy in Patients With Stage II/III Non-Small Cell Lung Cancer (Journal article)

Landau, D. B., Hughes, L., Baker, A., Bates, A. T., Bayne, M. C., Counsell, N., . . . Fenwick, J. D. (2016). IDEAL-CRT: A Phase 1/2 Trial of Isotoxic Dose-Escalated Radiation Therapy and Concurrent Chemotherapy in Patients With Stage II/III Non-Small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 95(5), 1367-1377. doi:10.1016/j.ijrobp.2016.03.031

DOI: 10.1016/j.ijrobp.2016.03.031

Continuous hyperfractionated accelerated radiotherapy - Escalated dose (CHART-ED): A phase I study (Journal article)

Hatton, M. Q. F., Hill, R., Fenwick, J. D., Morgan, S. A., Wilson, P. C., Atherton, P. J., . . . Paul, J. (2016). Continuous hyperfractionated accelerated radiotherapy - Escalated dose (CHART-ED): A phase I study. RADIOTHERAPY AND ONCOLOGY, 118(3), 471-477. doi:10.1016/j.radonc.2015.11.015

DOI: 10.1016/j.radonc.2015.11.015

ADSCaN: a randomised phase II study of Accelerated, Dose escalated, Sequential, Chemo-radiotherapy in Non-Small Cell Lung Cancer (Journal article)

Landaus, D., Faivre-Finn, C., Lester, J. F., Maguire, J., Paul, J., Mccartney, E., . . . Lawless, C. A. (2016). ADSCaN: a randomised phase II study of Accelerated, Dose escalated, Sequential, Chemo-radiotherapy in Non-Small Cell Lung Cancer. LUNG CANCER, 91, S68. doi:10.1016/S0169-5002(16)30205-7

DOI: 10.1016/S0169-5002(16)30205-7

F-18-Misonidazole PET-CT scan detection of occult bone metastasis (Journal article)

McGowan, D. R., Macpherson, R. E., Bradley, K. M., Fenwick, J. D., Gleeson, F. V., & Higgins, G. S. (2016). F-18-Misonidazole PET-CT scan detection of occult bone metastasis. THORAX, 71(1), 97. doi:10.1136/thoraxjnl-2015-207400

DOI: 10.1136/thoraxjnl-2015-207400

2015

Breakdown of Bragg-Gray behaviour for low-density detectors under electronic disequilibrium conditions in small megavoltage photon fields (Journal article)

Kumar, S., Fenwick, J. D., Underwood, T. S. A., Deshpande, D. D., Scott, A. J. D., & Nahum, A. E. (2015). Breakdown of Bragg-Gray behaviour for low-density detectors under electronic disequilibrium conditions in small megavoltage photon fields. PHYSICS IN MEDICINE AND BIOLOGY, 60(20), 8187-8212. doi:10.1088/0031-9155/60/20/8187

DOI: 10.1088/0031-9155/60/20/8187

Dose-Escalated Radiotherapy for NSCLC: Heart Doses versus Survival in IDEAL-CRT (Journal article)

Vivekanandan, S., Counsell, N., Parsons, E., Ngai, Y., Hughes, L., Hawkins, M., . . . Fenwick, J. D. (2015). Dose-Escalated Radiotherapy for NSCLC: Heart Doses versus Survival in IDEAL-CRT. JOURNAL OF THORACIC ONCOLOGY, 10(9), S384. Retrieved from http://gateway.webofknowledge.com/

Isotoxic Dose Escalation and Acceleration in Lung Cancer Chemoradiotherapy (Journal article)

Landau, D., Khan, I., Baker, A., Bates, A. T., Bayne, M. C., Counsell, N., . . . Fenwick, J. D. (2015). Isotoxic Dose Escalation and Acceleration in Lung Cancer Chemoradiotherapy. JOURNAL OF THORACIC ONCOLOGY, 10(9), S288-S289. Retrieved from http://gateway.webofknowledge.com/

Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism. (Journal article)

Lord, S. R., Patel, N., Liu, D., Fenwick, J., Gleeson, F., Buffa, F., & Harris, A. L. (2015). Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism.. Journal of the National Cancer Institute. Monographs, 2015(51), 81-86. doi:10.1093/jncimonographs/lgv011

DOI: 10.1093/jncimonographs/lgv011

Validation of a prototype DiodeAir for small field dosimetry (Journal article)

Underwood, T. S. A., Thompson, J., Bird, L., Scott, A. J. D., Patmore, P., Winter, H. C., . . . Fenwick, J. D. (2015). Validation of a prototype DiodeAir for small field dosimetry. PHYSICS IN MEDICINE AND BIOLOGY, 60(7), 2939-2953. doi:10.1088/0031-9155/60/7/2939

DOI: 10.1088/0031-9155/60/7/2939

2014

Letter regarding Meade et al. entitled "Models of acute mucosal tolerance to radiotherapy alone applied to synchronous chemo-radiation schedules in head and neck cancer" (Journal article)

Fenwick, J. D., Malik, Z., Nahum, A. E., & Mayles, W. P. M. (2014). Letter regarding Meade et al. entitled "Models of acute mucosal tolerance to radiotherapy alone applied to synchronous chemo-radiation schedules in head and neck cancer". TUMOR BIOLOGY, 35(12), 12777-12778. doi:10.1007/s13277-014-2874-0

DOI: 10.1007/s13277-014-2874-0

Improvement Using a New Bayesian Penalised Likelihood Reconstruction (QClear) on Contrast Recovery and Background Variability in the NEMA Image Quality Phantom and Patients (Conference Paper)

McGowan, D. R., Teoh, E. J., Franklin, J., Bradley, K. M., Gleeson, F. V., & Fenwick, J. D. (2014). Improvement Using a New Bayesian Penalised Likelihood Reconstruction (QClear) on Contrast Recovery and Background Variability in the NEMA Image Quality Phantom and Patients. In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Vol. 41 (pp. S172-S173). Retrieved from http://gateway.webofknowledge.com/

Interstitial diffusion and the relationship between compartment modelling and multi-scale spatial-temporal modelling of F-18-FLT tumour uptake dynamics (Journal article)

Liu, D., Chalkidou, A., Landau, D. B., Marsden, P. K., & Fenwick, J. D. (2014). Interstitial diffusion and the relationship between compartment modelling and multi-scale spatial-temporal modelling of F-18-FLT tumour uptake dynamics. PHYSICS IN MEDICINE AND BIOLOGY, 59(17), 5175-5202. doi:10.1088/0031-9155/59/17/5175

DOI: 10.1088/0031-9155/59/17/5175

Optimizing Collimator Margins for Isotoxically Dose-Escalated Conformal Radiation Therapy of Non-Small Cell Lung Cancer (Journal article)

Warren, S., Panettieri, V., Panakis, N., Bates, N., Lester, J. F., Jain, P., . . . Fenwick, J. D. (2014). Optimizing Collimator Margins for Isotoxically Dose-Escalated Conformal Radiation Therapy of Non-Small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 88(5), 1148-1153. doi:10.1016/j.ijrobp.2013.12.034

DOI: 10.1016/j.ijrobp.2013.12.034

F-18-FLT uptake kinetics in head and neck squamous cell carcinoma: A PET imaging study (Journal article)

Liu, D., Chalkidou, A., Landau, D. B., Marsden, P. K., & Fenwick, J. D. (2014). F-18-FLT uptake kinetics in head and neck squamous cell carcinoma: A PET imaging study. MEDICAL PHYSICS, 41(4). doi:10.1118/1.4868462

DOI: 10.1118/1.4868462

Dose escalation in the I-START trial - ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer (Journal article)

Nixon, L. S., Lester, J. F., Mayles, P., Mayles, H., Parsons, E., Ionescu, A., . . . Griffiths, G. (2014). Dose escalation in the I-START trial - ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer. LUNG CANCER, 83, S54. doi:10.1016/S0169-5002(14)70149-7

DOI: 10.1016/S0169-5002(14)70149-7

2013

Estimation of input functions from dynamic [F-18]FLT PET studies of the head and neck with correction for partial volume effects (Journal article)

Hackett, S. L., Liu, D., Chalkidou, A., Marsden, P., Landau, D., & Fenwick, J. D. (2013). Estimation of input functions from dynamic [F-18]FLT PET studies of the head and neck with correction for partial volume effects. EJNMMI RESEARCH, 3. doi:10.1186/2191-219X-3-84

DOI: 10.1186/2191-219X-3-84

Mass-density compensation can improve the performance of a range of different detectors under non-equilibrium conditions (Journal article)

Underwood, T. S. A., Winter, H. C., Hill, M. A., & Fenwick, J. D. (2013). Mass-density compensation can improve the performance of a range of different detectors under non-equilibrium conditions. PHYSICS IN MEDICINE AND BIOLOGY, 58(23), 8295-8310. doi:10.1088/0031-9155/58/23/8295

DOI: 10.1088/0031-9155/58/23/8295

MULTI-SCALE SPATIAL-TEMPORAL MODELLING OF 18F-FLT DYNAMICS AND ITS RELATION TO 3-COMPARTMENT MODEL (Conference Paper)

Liu, D., Chalkidou, A., Marsden, P. K., Fenwick, J. D., & ASME. (2014). MULTI-SCALE SPATIAL-TEMPORAL MODELLING OF 18F-FLT DYNAMICS AND ITS RELATION TO 3-COMPARTMENT MODEL. In PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2013, VOL 3A. Retrieved from http://gateway.webofknowledge.com/

I-START TRIAL: A UK PHASE I/II TRIAL OF ISOTOXIC ACCELERATED RADIOTHERAPY IN LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER (Journal article)

Lester, J., Nixon, L. S., Eswar, C., Mohammed, N., Malik, Z., Cowles, R., . . . Griffiths, G. (2013). I-START TRIAL: A UK PHASE I/II TRIAL OF ISOTOXIC ACCELERATED RADIOTHERAPY IN LOCALLY ADVANCED NON-SMALL CELL LUNG CANCER. JOURNAL OF THORACIC ONCOLOGY, 8, S1134. Retrieved from http://gateway.webofknowledge.com/

IDEAL CRT: ISOTOXIC DOSE ESCALATION AND ACCELERATION IN LUNG CANCER CHEMORADIOTHERAPY - A PHASE I/II TRIAL OF CONCURRENT CHEMORADIATION WITH DOSE-ESCALATED RADIOTHERAPY IN PATIENTS WITH STAGE II OR STAGE III NON-SMALL CELL LUNG CANCER (Journal article)

Landau, D. B., Khan, I., Ngai, Y., Hughes, L. L., Miles, E., Wilkinson, D., . . . Fenwick, J. (2013). IDEAL CRT: ISOTOXIC DOSE ESCALATION AND ACCELERATION IN LUNG CANCER CHEMORADIOTHERAPY - A PHASE I/II TRIAL OF CONCURRENT CHEMORADIATION WITH DOSE-ESCALATED RADIOTHERAPY IN PATIENTS WITH STAGE II OR STAGE III NON-SMALL CELL LUNG CANCER. JOURNAL OF THORACIC ONCOLOGY, 8, S190. Retrieved from http://gateway.webofknowledge.com/

F-18-FLT Uptake Kinetics in Head and Neck Squamous Cell Carcinoma: A PET Imaging Study (Conference Paper)

Liu, D., Chalkidou, A., Landau, D., Marsden, P., & Fenwick, J. (2013). F-18-FLT Uptake Kinetics in Head and Neck Squamous Cell Carcinoma: A PET Imaging Study. In INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Vol. 87 (pp. S688-S689). doi:10.1016/j.ijrobp.2013.06.1826

DOI: 10.1016/j.ijrobp.2013.06.1826

Detector density and small field dosimetry: Integral versus point dose measurement schemes (Journal article)

Underwood, T. S. A., Winter, H. C., Hill, M. A., & Fenwick, J. D. (2013). Detector density and small field dosimetry: Integral versus point dose measurement schemes. MEDICAL PHYSICS, 40(8). doi:10.1118/1.4812687

DOI: 10.1118/1.4812687

Using cavity theory to describe the dependence on detector density of dosimeter response in non-equilibrium small fields (Journal article)

Fenwick, J. D., Kumar, S., Scott, A. J. D., & Nahum, A. E. (2013). Using cavity theory to describe the dependence on detector density of dosimeter response in non-equilibrium small fields. PHYSICS IN MEDICINE AND BIOLOGY, 58(9), 2901-2923. doi:10.1088/0031-9155/58/9/2901

DOI: 10.1088/0031-9155/58/9/2901

A phase I/II trial of concurrent chemo-radiation with dose-escalated radiotherapy in patients with stage II or stage III non-small cell lung cancer (Journal article)

Landau, D. B., Miles, E., Illsley, M., Laurence, V., Hughes, S., Ngai, Y., . . . Fenwick, J. (2013). A phase I/II trial of concurrent chemo-radiation with dose-escalated radiotherapy in patients with stage II or stage III non-small cell lung cancer. LUNG CANCER, 79, S64-S65. doi:10.1016/S0169-5002(13)70186-7

DOI: 10.1016/S0169-5002(13)70186-7

TU-C-108-03: Beyond the Alfonso Formalism for Small Field Dosimetry: A New Metric, New Detectors, Or Both? (Conference Paper)

Underwood, T. S. A., Winter, H. C., Hill, M. A., & Fenwick, J. D. (2013). TU-C-108-03: Beyond the Alfonso Formalism for Small Field Dosimetry: A New Metric, New Detectors, Or Both?. In Medical Physics Vol. 40 (pp. 430-431). Wiley. doi:10.1118/1.4815367

DOI: 10.1118/1.4815367

2012

Tomotherapy-like versus VMAT-like treatments: A multicriteria comparison for a prostate geometry (Journal article)

Pardo-Montero, J., & Fenwick, J. D. (2012). Tomotherapy-like versus VMAT-like treatments: A multicriteria comparison for a prostate geometry. MEDICAL PHYSICS, 39(12), 7418-7429. doi:10.1118/1.4768159

DOI: 10.1118/1.4768159

A Comparison of 4 Target Volume Definitions for Pancreatic Cancer: Two Concepts Including the Lymphatics (RTOG and ARO) and 2 Concepts Only Treating the Primary Tumor (Michigan and UK-SCALOP) (Conference Paper)

Brunner, T., Fokas, E., Eccles, C. L., Fenwick, J., & McKenna, G. (2012). A Comparison of 4 Target Volume Definitions for Pancreatic Cancer: Two Concepts Including the Lymphatics (RTOG and ARO) and 2 Concepts Only Treating the Primary Tumor (Michigan and UK-SCALOP). In INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Vol. 84 (pp. S322). doi:10.1016/j.ijrobp.2012.07.844

DOI: 10.1016/j.ijrobp.2012.07.844

Dilemmas concerning dose distribution and the influence of relative biological effect in proton beam therapy of medulloblastoma (Journal article)

Jones, B., Wilson, P., Nagano, A., Fenwick, J., & McKenna, G. (2012). Dilemmas concerning dose distribution and the influence of relative biological effect in proton beam therapy of medulloblastoma. BRITISH JOURNAL OF RADIOLOGY, 85(1018), E912-E918. doi:10.1259/bjr/24498486

DOI: 10.1259/bjr/24498486

Characterizing the influence of detector density on dosimeter response in non-equilibrium small photon fields (Journal article)

Scott, A. J. D., Kumar, S., Nahum, A. E., & Fenwick, J. D. (2012). Characterizing the influence of detector density on dosimeter response in non-equilibrium small photon fields. PHYSICS IN MEDICINE AND BIOLOGY, 57(14), 4461-4476. doi:10.1088/0031-9155/57/14/4461

DOI: 10.1088/0031-9155/57/14/4461

IMPACT OF SCHEDULE DURATION ON HEAD AND NECK RADIOTHERAPY: ACCELERATED TUMOR REPOPULATION VERSUS COMPENSATORY MUCOSAL PROLIFERATION (Journal article)

Fenwick, J. D., Pardo-Montero, J., Nahum, A. E., & Malik, Z. I. (2012). IMPACT OF SCHEDULE DURATION ON HEAD AND NECK RADIOTHERAPY: ACCELERATED TUMOR REPOPULATION VERSUS COMPENSATORY MUCOSAL PROLIFERATION. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 82(2), 1021-1030. doi:10.1016/j.ijrobp.2010.12.048

DOI: 10.1016/j.ijrobp.2010.12.048

Numerical study of the mechanics of indentation bending tests of thin membranes and inverse materials parameters prediction (Conference Paper)

Elkut, F., Bradley, G. R., Krywonos, J., Fenwick, J., & Ren, X. J. (2012). Numerical study of the mechanics of indentation bending tests of thin membranes and inverse materials parameters prediction. In COMPUTATIONAL MATERIALS SCIENCE Vol. 52 (pp. 123-127). doi:10.1016/j.commatsci.2011.03.025

DOI: 10.1016/j.commatsci.2011.03.025

The I-START trial: ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer (Journal article)

Lester, J. F., Nixon, L., Mayles, P., Mayles, H., Tsang, Y., Ionescu, A., . . . Griffiths, G. (2012). The I-START trial: ISoToxic Accelerated RadioTherapy in locally advanced non-small cell lung cancer. LUNG CANCER, 75, S51. doi:10.1016/S0169-5002(12)70157-5

DOI: 10.1016/S0169-5002(12)70157-5

2011

A comparison of imaging schedules for prostate radiotherapy including online tracking techniques (Journal article)

Baker, A., Fenwick, J. D., Mayles, W. P., Syndikus, I., & Wong, H. (2011). A comparison of imaging schedules for prostate radiotherapy including online tracking techniques. Journal of Radiotherapy in Practice, 10(4), 239-249. doi:10.1017/s146039691000052x

DOI: 10.1017/s146039691000052x

18F-FLT PET/CT sequential imaging to quantify tumour proliferation during radiotherapy in patients with lung and head and neck cancer. (Journal article)

Chalkidou, A., Landau, D., Guerrero, T., Somer, E., Fenwick, J., O'Doherty, M., & Marsden, P. (2011). 18F-FLT PET/CT sequential imaging to quantify tumour proliferation during radiotherapy in patients with lung and head and neck cancer.. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 38, S116. Retrieved from http://gateway.webofknowledge.com/

18F-FLT PET/CT Sequential Imaging to Quantify Tumour Proliferation During Radiotherapy in Patients With Lung and Head and Neck Cancer (Conference Paper)

Chalkidou, A., Landau, D., Guerrero, T., Fenwick, J., Somer, E., O'Doherty, M., & Marsden, P. (2011). 18F-FLT PET/CT Sequential Imaging to Quantify Tumour Proliferation During Radiotherapy in Patients With Lung and Head and Neck Cancer. In EUROPEAN JOURNAL OF CANCER Vol. 47 (pp. S171). doi:10.1016/S0959-8049(11)70900-5

DOI: 10.1016/S0959-8049(11)70900-5

Numbers of beam angles required for near-optimal IMRT: Theoretical limits and numerical studies (Journal article)

Fenwick, J. D., & Pardo-Montero, J. (2011). Numbers of beam angles required for near-optimal IMRT: Theoretical limits and numerical studies. MEDICAL PHYSICS, 38(8), 4518-4530. doi:10.1118/1.3606457

DOI: 10.1118/1.3606457

The effect of different control point sampling sequences on convergence of VMAT inverse planning (Journal article)

Montero, J. P., & Fenwick, J. D. (2011). The effect of different control point sampling sequences on convergence of VMAT inverse planning. PHYSICS IN MEDICINE AND BIOLOGY, 56(8), 2569-2583. doi:10.1088/0031-9155/56/8/015

DOI: 10.1088/0031-9155/56/8/015

SU-E-T-657: Quantitative Tumour Control Predictions for the Radiotherapy of Non-Small-Cell Lung Tumours (Conference Paper)

Nahum, A., Uzan, J., Jain, P., Malik, Z., Fenwick, J., & Baker, C. (2011). SU-E-T-657: Quantitative Tumour Control Predictions for the Radiotherapy of Non-Small-Cell Lung Tumours. In Medical Physics Vol. 38 (pp. 3641). Wiley. doi:10.1118/1.3612620

DOI: 10.1118/1.3612620

2010

MRI image-based FE modelling of the pelvis system and bladder filling (Journal article)

Krywonos, J., Fenwick, J., Elkut, F., Jenkinson, I., Liu, Y. H., Brunt, J. N. H., . . . Ren, X. J. (2010). MRI image-based FE modelling of the pelvis system and bladder filling. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 13(6), 669-676. doi:10.1080/10255840903446961

DOI: 10.1080/10255840903446961

Influence of dose calculation algorithms on isotoxic dose-escalation of non-small cell lung cancer radiotherapy (Journal article)

Panettieri, V., Malik, Z. I., Eswar, C. V., Landau, D. B., Thornton, J. M. C., Nahum, A. E., . . . Fenwick, J. D. (2010). Influence of dose calculation algorithms on isotoxic dose-escalation of non-small cell lung cancer radiotherapy. RADIOTHERAPY AND ONCOLOGY, 97(3), 418-424. doi:10.1016/j.radonc.2010.06.015

DOI: 10.1016/j.radonc.2010.06.015

Nutlin-3, the small-molecule inhibitor of MDM2, promotes senescence and radiosensitises laryngeal carcinoma cells harbouring wild-type p53 (Journal article)

Arya, A. K., El-Fert, A., Devling, T., Eccles, R. M., Aslam, M. A., Rubbi, C. P., . . . Boyd, M. T. (2010). Nutlin-3, the small-molecule inhibitor of MDM2, promotes senescence and radiosensitises laryngeal carcinoma cells harbouring wild-type p53. BRITISH JOURNAL OF CANCER, 103(2), 186-195. doi:10.1038/sj.bjc.6605739

DOI: 10.1038/sj.bjc.6605739

An approach to multiobjective optimization of rotational therapy. II. Pareto optimal surfaces and linear combinations of modulated blocked arcs for a prostate geometry. (Journal article)

Pardo-Montero, J., & Fenwick, J. D. (2010). An approach to multiobjective optimization of rotational therapy. II. Pareto optimal surfaces and linear combinations of modulated blocked arcs for a prostate geometry.. Medical physics, 37(6Part1), 2606-2616. doi:10.1118/1.3427410

DOI: 10.1118/1.3427410

An approach to multiobjective optimization of rotational therapy. II. Pareto optimal surfaces and linear combinations of modulated blocked arcs for a prostate geometry (Journal article)

Pardo-Montero, J., & Fenwick, J. D. (2010). An approach to multiobjective optimization of rotational therapy. II. Pareto optimal surfaces and linear combinations of modulated blocked arcs for a prostate geometry. MEDICAL PHYSICS, 37(6), 2606-2616. doi:10.1118/1.3427410

DOI: 10.1118/1.3427410

Homogenized blocked arcs for multicriteria optimization of radiotherapy: Analytical and numerical solutions (Journal article)

Fenwick, J. D., & Pardo-Montero, J. (2010). Homogenized blocked arcs for multicriteria optimization of radiotherapy: Analytical and numerical solutions. MEDICAL PHYSICS, 37(5), 2194-2206. doi:10.1118/1.3377771

DOI: 10.1118/1.3377771

2009

MODELLING AND MEASURING SMALL RADIOTHERAPY PHOTON FIELDS (Journal article)

Scott, A., Nahum, A. E., & Fenwick, J. (2009). MODELLING AND MEASURING SMALL RADIOTHERAPY PHOTON FIELDS. RADIOTHERAPY AND ONCOLOGY, 92, S53. doi:10.1016/S0167-8140(12)72726-3

DOI: 10.1016/S0167-8140(12)72726-3

Monte Carlo modeling of small photon fields: Quantifying the impact of focal spot size on source occlusion and output factors, and exploring miniphantom design for small-field measurements. (Journal article)

Scott, A. J. D., Nahum, A. E., & Fenwick, J. D. (2009). Monte Carlo modeling of small photon fields: Quantifying the impact of focal spot size on source occlusion and output factors, and exploring miniphantom design for small-field measurements.. Medical physics, 36(7), 3132-3144. doi:10.1118/1.3152866

DOI: 10.1118/1.3152866

An approach to multiobjective optimization of rotational therapy (Journal article)

Pardo-Montero, J., & Fenwick, J. D. (2009). An approach to multiobjective optimization of rotational therapy. MEDICAL PHYSICS, 36(7), 3292-3303. doi:10.1118/1.3151806

DOI: 10.1118/1.3151806

Monte Carlo modeling of small photon fields: Quantifying the impact of focal spot size on source occlusion and output factors, and exploring miniphantom design for small-field measurements (Journal article)

Scott, A. J. D., Nahum, A. E., & Fenwick, J. D. (2009). Monte Carlo modeling of small photon fields: Quantifying the impact of focal spot size on source occlusion and output factors, and exploring miniphantom design for small-field measurements. MEDICAL PHYSICS, 36(7), 3132-3144. doi:10.1118/1.3152866

DOI: 10.1118/1.3152866

An Experimental and Numerical Program to Study the Properties of Thin Biological Membranes and Water Filling Process (Conference Paper)

Elkut, F., Krywonos, J., Fenwick, J., Jenkinson, I., & Ren, X. J. (2010). An Experimental and Numerical Program to Study the Properties of Thin Biological Membranes and Water Filling Process. In WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING, VOL 25, PT 4: IMAGE PROCESSING, BIOSIGNAL PROCESSING, MODELLING AND SIMULATION, BIOMECHANICS Vol. 25 (pp. 2178-2180). Retrieved from http://gateway.webofknowledge.com/

Escalation and Intensification of Radiotherapy for Stage III Non-small Cell Lung Cancer: Opportunities for Treatment Improvement (Journal article)

Fenwick, J. D., Nahum, A. E., Malik, Z. I., Eswar, C. V., Hatton, M. Q., Laurence, V. M., . . . Landau, D. B. (2009). Escalation and Intensification of Radiotherapy for Stage III Non-small Cell Lung Cancer: Opportunities for Treatment Improvement. CLINICAL ONCOLOGY, 21(4), 343-360. doi:10.1016/j.clon.2008.12.011

DOI: 10.1016/j.clon.2008.12.011

2008

Numerical Study of Effects of Bladder Filling on Prostate Positioning In Radiotherapy (Journal article)

Krywonos, J., Elkut, F., Brunt, J., Malik, Z., Eswar, C., Fenwick, J., & Ren, X. J. (2009). Numerical Study of Effects of Bladder Filling on Prostate Positioning In Radiotherapy. 4TH EUROPEAN CONFERENCE OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOLOGICAL ENGINEERING, 22(1-3), 2655-2658. Retrieved from http://gateway.webofknowledge.com/

Using a Monte Carlo model to predict dosimetric properties of small radiotherapy photon fields. (Journal article)

Scott, A. J. D., Nahum, A. E., & Fenwick, J. D. (2008). Using a Monte Carlo model to predict dosimetric properties of small radiotherapy photon fields.. Medical physics, 35(10), 4671-4684. doi:10.1118/1.2975223

DOI: 10.1118/1.2975223

Using a Monte Carlo model to predict dosimetric properties of small radiotherapy photon fields (Journal article)

Scott, A. J. D., Nahum, A. E., & Fenwick, J. D. (2008). Using a Monte Carlo model to predict dosimetric properties of small radiotherapy photon fields. MEDICAL PHYSICS, 35(10), 4671-4684. doi:10.1118/1.2975223

DOI: 10.1118/1.2975223

CONFIDENCE INTERVALS ON NTCP ESTIMATES FOR INDIVIDUALISED DOSE-PRESCRIPTION (Journal article)

Rutkowska, E., Baker, C., Eswar, C., Fenwick, J., Littler, J., Malik, Z., & Nahum, A. E. (2008). CONFIDENCE INTERVALS ON NTCP ESTIMATES FOR INDIVIDUALISED DOSE-PRESCRIPTION. RADIOTHERAPY AND ONCOLOGY, 88, S29. Retrieved from http://gateway.webofknowledge.com/

Early mucosal reactions during and after head-and-neck radiotherapy: Dependence of treatment tolerance on radiation dose and schedule duration (Journal article)

Fenwick, J. D., Lawrence, G. P., Malik, Z., Nahum, A. E., & Mayles, W. P. M. (2008). Early mucosal reactions during and after head-and-neck radiotherapy: Dependence of treatment tolerance on radiation dose and schedule duration. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(2), 625-634. doi:10.1016/j.ijrobp.2008.02.008

DOI: 10.1016/j.ijrobp.2008.02.008

'Advances in the delivery of intensity-modulated radiotherapy' (Chapter)

Fenwick, J. D., Riley, S. W., & Scott, A. J. D. (2008). 'Advances in the delivery of intensity-modulated radiotherapy'. In S. M. Bentzen, P. M. Harari, W. A. Tomé, & M. P. Mehta (Eds.), Radiation Oncology Advances (pp. 193-214). New York: Springer-Verlag.

'Predicting small photon field dosimetry with a monte carlo model' (Journal article)

Scott, A., Nahum, A. E., & Fenwick, J. (2008). 'Predicting small photon field dosimetry with a monte carlo model'. Radiotherapy and Oncology, 88, S35.

Advances in intensity-modulated radiotherapy delivery. (Journal article)

Fenwick, J. D., Riley, S. W., & Scott, A. J. D. (2008). Advances in intensity-modulated radiotherapy delivery.. Cancer treatment and research, 139, 193-214.

2007

ISO-NTCP customisation of the prescription dose in lung-tumour radiotherapy (Conference Paper)

Malik, Z., Eswar, C., Dobson, J., Fenwick, J., & Nahum, A. (2007). ISO-NTCP customisation of the prescription dose in lung-tumour radiotherapy. In RADIOTHERAPY AND ONCOLOGY Vol. 84 (pp. S278-S279). Retrieved from http://gateway.webofknowledge.com/

Oesophageal toxicity-impact of radiation dose, time, volume and chemotherapy (Conference Paper)

Fenwick, J. (2007). Oesophageal toxicity-impact of radiation dose, time, volume and chemotherapy. In RADIOTHERAPY AND ONCOLOGY Vol. 84 (pp. S122). Retrieved from http://gateway.webofknowledge.com/

Dose-individualisation for lung cancer radiotherapy - are we ready? (Journal article)

Malik, Z., Eswar, C., Dobson, J., Fenwick, J., & Nahum, A. E. (2007). Dose-individualisation for lung cancer radiotherapy - are we ready?. LUNG CANCER, 57, S9. doi:10.1016/S0169-5002(07)70357-4

DOI: 10.1016/S0169-5002(07)70357-4

UK proposal for three parallel dose escalation studies in radiotherapy (RT) for Stage I-III non-small cell lung cancer (NSCLQC)-DEAL-RT (Journal article)

Hughes, S., Mohammed, N., Lester, J., Landau, D., Deehan, C., Hatton, M., . . . Stephens, R. (2007). UK proposal for three parallel dose escalation studies in radiotherapy (RT) for Stage I-III non-small cell lung cancer (NSCLQC)-DEAL-RT. LUNG CANCER, 57, S8. Retrieved from http://gateway.webofknowledge.com/

Biomathematical model-based analysis of a standard UK dose and fractionation lung tumour radiotherapy protocol (Journal article)

Malik, Z., Vee, C. E., Dobson, J., Fenwick, J., & Nahum, A. E. (2007). Biomathematical model-based analysis of a standard UK dose and fractionation lung tumour radiotherapy protocol. CLINICAL ONCOLOGY, 19(3), S38. doi:10.1016/j.clon.2007.01.390

DOI: 10.1016/j.clon.2007.01.390

'IMRT-based 4D stereotactic radiotherapy for early stage inoperable lung cancer: initial clinical validation of a radiobiologic model' (Journal article)

Hodge, C. W., Tomé, W. A., Khuntia, D., Weigel, T., Plazzi-Churas, K. L., Fenwick, J. D., . . . Mehta, M. P. (2007). 'IMRT-based 4D stereotactic radiotherapy for early stage inoperable lung cancer: initial clinical validation of a radiobiologic model'. International Journal of Radiation Oncology, Biology, Physics, 69, S487.

2006

Tomotherapy and other innovative IMRT delivery systems (Journal article)

Fenwick, J. D., Tome, W. A., Soisson, E. T., Mehta, M. P., & Mackie, T. R. (2006). Tomotherapy and other innovative IMRT delivery systems. SEMINARS IN RADIATION ONCOLOGY, 16(4), 199-208. doi:10.1016/j.semradonc.2006.04.002

DOI: 10.1016/j.semradonc.2006.04.002

Delay differential equations and the dose-time dependence of early radiotherapy reactions (Journal article)

Fenwick, J. D. (2006). Delay differential equations and the dose-time dependence of early radiotherapy reactions. MEDICAL PHYSICS, 33(9), 3526-3540. doi:10.1118/1.2241995

DOI: 10.1118/1.2241995

Does a local bystander effect necessitate a revision of TCP models that are based on observed clinical data? (Journal article)

Tome, W. A., Fenwick, J. D., & Bentzen, S. M. (2006). Does a local bystander effect necessitate a revision of TCP models that are based on observed clinical data?. ACTA ONCOLOGICA, 45(4), 406-411. doi:10.1080/02841860500468935

DOI: 10.1080/02841860500468935

'Delay differential equations and the dose-time dependence of early radiotherapy reactions' (Journal article)

Fenwick, J. D. (2006). 'Delay differential equations and the dose-time dependence of early radiotherapy reactions'. Radiotherapy and Oncology, 78, S45.

How can tumor effect and normal tissue effect be balanced in stereotactic body radiotherapy (Journal article)

Tome, W. A., Fenwick, J. D., & Mehta, M. P. (2006). How can tumor effect and normal tissue effect be balanced in stereotactic body radiotherapy. Radiosurgery, Vol 6, 6, 86-97. doi:10.1159/000093718

DOI: 10.1159/000093718

Lung cancer, modern radiotherapy and modified fractionation. (Journal article)

Fenwick, J. D. (2006). Lung cancer, modern radiotherapy and modified fractionation.. Clinical Oncology, 18, S5.

QA for tomotherapy (Conference Paper)

Tome, W., Jaradat, H., Westerly, D., Fenwick, J., Orton, N., Mackie, T., & Paliwal, B. (2006). QA for tomotherapy. In MEDICAL PHYSICS Vol. 33 (pp. 2282). doi:10.1118/1.2241911

DOI: 10.1118/1.2241911

2005

Potential for radiation therapy technology innovations to permit dose escalation for non-small-cell lung cancer (Journal article)

Manon, R. R., Jaradat, H., Patel, R., Zhang, T., Fenwick, J., Tome, W., . . . Mehta, M. (2005). Potential for radiation therapy technology innovations to permit dose escalation for non-small-cell lung cancer. CLINICAL LUNG CANCER, 7(2), 107-113. doi:10.3816/CLC.2005.n.025

DOI: 10.3816/CLC.2005.n.025

The helical tomotherapy thread effect (Journal article)

Kissick, M. W., Fenwick, J., James, J. A., Jerai, R., Kapatoes, J. M., Keller, H., . . . Soisson, E. T. (2005). The helical tomotherapy thread effect. MEDICAL PHYSICS, 32(5), 1414-1423. doi:10.1118/1.1896453

DOI: 10.1118/1.1896453

Modelling simple helically delivered dose distributions (Journal article)

Fenwick, J. D., Tome, W. A., Kissick, M. W., & Mackie, T. R. (2005). Modelling simple helically delivered dose distributions. PHYSICS IN MEDICINE AND BIOLOGY, 50(7), 1505-1517. doi:10.1088/0031-9155/50/7/013

DOI: 10.1088/0031-9155/50/7/013

2004

A challenge to traditional radiation oncology (Journal article)

Fowler, J. F., Tome, W. A., Fenwick, J. D., & Mehta, M. P. (2004). A challenge to traditional radiation oncology. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 60(4), 1241-1256. doi:10.1016/j.ijrobp.2004.07.691

DOI: 10.1016/j.ijrobp.2004.07.691

Quality assurance of a helical tomotherapy machine (Journal article)

Fenwick, J. D., Tome, W. A., Jaradat, H. A., Hui, S. K., James, J. A., Balog, J. P., . . . Paliwal, B. R. (2004). Quality assurance of a helical tomotherapy machine. PHYSICS IN MEDICINE AND BIOLOGY, 49(13), 2933-2953. doi:10.1088/0031-9155/49/13/012

DOI: 10.1088/0031-9155/49/13/012

Integral dose in external beam photon radiotherapy (Conference Paper)

Mackie, T., Kissick, M., Jeraj, R., Tome, W., Fenwick, J., Olivera, G., & Ritter, M. (2004). Integral dose in external beam photon radiotherapy. In MEDICAL PHYSICS Vol. 31 (pp. 1721). Retrieved from http://gateway.webofknowledge.com/

Patient-specific dose verification and synchronization quality assurance tests for helical tornotherapy using film (Conference Paper)

James, J., Hui, S., Mackie, T., & Fenwick, J. (2004). Patient-specific dose verification and synchronization quality assurance tests for helical tornotherapy using film. In MEDICAL PHYSICS Vol. 31 (pp. 1845). Retrieved from http://gateway.webofknowledge.com/

Geometric leaf placement strategies (Journal article)

Fenwick, J. D., Temple, S. W. P., Clements, R. W., Lawrence, G. P., Mayles, H. M. O., & Mayles, W. P. M. (2004). Geometric leaf placement strategies. PHYSICS IN MEDICINE AND BIOLOGY, 49(8), 1505-1519. doi:10.1088/0031-9155/49/8/009

DOI: 10.1088/0031-9155/49/8/009

Analysis of radiation-induced liver disease using the Lyman NTCP model: In regard to Dawson et al. IJROBP 2002;53:810-821 (Journal article)

Tome, W. A., & Fenwick, J. D. (2004). Analysis of radiation-induced liver disease using the Lyman NTCP model: In regard to Dawson et al. IJROBP 2002;53:810-821. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 58(4), 1318-1319. doi:10.1016/j.ijrobp.2003.10.052

DOI: 10.1016/j.ijrobp.2003.10.052

Helical tomotherapy as a means of delivering accelerated partial breast irradiation (Journal article)

Hui, S. K., Das, R. K., Kapatoes, J., Oliviera, G., Becker, S., Odau, H., . . . Welsh, J. S. (2004). Helical tomotherapy as a means of delivering accelerated partial breast irradiation. TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 3(6), 639-646. doi:10.1177/153303460400300614

DOI: 10.1177/153303460400300614

2003

How low is the alpha/beta ratio for prostate cancer? In regard to Wang et al., IJROBP 2003;55 : 194-203 (Journal article)

Fowler, J. F., Ritter, M. A., Fenwick, J. D., & Chappell, R. J. (2003). How low is the alpha/beta ratio for prostate cancer? In regard to Wang et al., IJROBP 2003;55 : 194-203. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 57(2), 593-595. doi:10.1016/S0360-3016(03)00364-X

DOI: 10.1016/S0360-3016(03)00364-X

2001

Series model volume effects in a population of non-identical patients: how low is low? (Journal article)

Fenwick, J., & Nahum, A. E. (2001). Series model volume effects in a population of non-identical patients: how low is low?. PHYSICS IN MEDICINE AND BIOLOGY, 46(7), 1815-1834. doi:10.1088/0031-9155/46/7/306

DOI: 10.1088/0031-9155/46/7/306

An ntcp formula for the series model with a Yaes-type functional subunit mechanism (Journal article)

Fenwick, J. D. (2001). An ntcp formula for the series model with a Yaes-type functional subunit mechanism. PHYSICS IN MEDICINE AND BIOLOGY, 46(2), N33-N38. doi:10.1088/0031-9155/46/2/401

DOI: 10.1088/0031-9155/46/2/401

Correlations between dose-surface histograms and the incidence of long-term rectal bleeding following conformal or conventional radiotherapy treatment of prostate cancer (Journal article)

Fenwick, J. D., Khoo, V. S., Nahum, A. E., Sanchez-Nieto, B., & Dearnaley, D. P. (2001). Correlations between dose-surface histograms and the incidence of long-term rectal bleeding following conformal or conventional radiotherapy treatment of prostate cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 49(2), 473-480. doi:10.1016/S0360-3016(00)01496-6

DOI: 10.1016/S0360-3016(00)01496-6

Impact of dose-distribution uncertainties on rectal ntcp modeling I: Uncertainty estimates (Journal article)

Fenwick, J. D., & Nahum, A. E. (2001). Impact of dose-distribution uncertainties on rectal ntcp modeling I: Uncertainty estimates. MEDICAL PHYSICS, 28(4), 560-569. doi:10.1118/1.1333746

DOI: 10.1118/1.1333746

Impact of dose-distribution uncertainties on rectal ntcp modeling II: Uncertainty implications (Journal article)

Fenwick, J. D. (2001). Impact of dose-distribution uncertainties on rectal ntcp modeling II: Uncertainty implications. MEDICAL PHYSICS, 28(4), 570-581. doi:10.1118/1.1355307

DOI: 10.1118/1.1355307

2000

An analysis of the relationship between radiosensitivity and volume effects in tumor control probability modeling. (Journal article)

Buffa, F. M., Fenwick, J. D., & Nahum, A. E. (2000). An analysis of the relationship between radiosensitivity and volume effects in tumor control probability modeling.. Medical physics, 27(6), 1258-1265. doi:10.1118/1.599003

DOI: 10.1118/1.599003

Biological modeling of pelvic radiotherapy: Potential gains from conformal techniques (Journal article)

Fenwick, J. (2000). Biological modeling of pelvic radiotherapy: Potential gains from conformal techniques. Medical Physics, 27(5), 1207. doi:10.1118/1.598987

DOI: 10.1118/1.598987

1999

Concerning Roberts and Hendry IJROBP 1998;41:689-699. (Journal article)

Buffa, F. M., Fenwick, J. D., & Nahum, A. E. (1999). Concerning Roberts and Hendry IJROBP 1998;41:689-699.. International journal of radiation oncology, biology, physics, 44(3), 737-739.

1998

Predicting the radiation control probability of heterogeneous tumour ensembles: data analysis and parameter estimation using a closed-form expression. (Journal article)

Fenwick, J. D. (1998). Predicting the radiation control probability of heterogeneous tumour ensembles: data analysis and parameter estimation using a closed-form expression.. Physics in medicine and biology, 43(8), 2159-2178. doi:10.1088/0031-9155/43/8/012

DOI: 10.1088/0031-9155/43/8/012

Spectral reconstruction of clinical megavoltage photon beams and the implications of spectral determination on the dosimetry of such beams (Journal article)

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