Dr Janet Risk BSc PhD PgCert (HE)

Honorary Senior Lecturer in Dental Genetics Molecular & Clinical Cancer Medicine

Research

The utility of infrared imaging in the early diagnosis of oral cancer

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The role of tumour stroma in HPV negative oral squamous cell carcinoma

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iRhom2 and ADAM17 in oesophageal cancer

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Research Grants

Clinical and technical validation of infrared absorbance spectra to predict malignant transformation in oral potentially malignant disorders (OPMDs)

CANCER RESEARCH UK (UK)

October 2023 - September 2026

Whole genome analysis of PVL

BRITISH ASSOCIATION OF ORAL MAXILLOFACIAL SURGEONS (UK)

January 2018 - December 2018

Novel therapeutic approaches for personalised therapy of Head and Neck cancer

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

April 2017 - April 2020

iRHOM/ADAM17 in oesophageal squamous cell cancer

CANCER RESEARCH UK (UK)

May 2015 - April 2020

The role of RHBDF2 in oesophageal cancer

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

February 2013 - February 2014

Cytoglobin expression and function in oesophageal cancer.

CANCER RESEARCH UK (UK)

March 2009 - February 2012

Identification and characterisation of the familial tylosis with oesophageal cancer (TOC) gene.

CANCER RESEARCH UK (UK)

June 2002 - May 2004

Genetic, protein and functional analyses on the origin of the skin disorder, tylosis A.

BRITISH SKIN FOUNDATION (UK)

January 2005 - May 2007

Extended physical mapping of the Tylosis Oesophageal Cancer (TOC) gene region on 17q25 in order to characterise candidate TOC genes.

CANCER RESEARCH UK (UK)

June 1999 - May 2002

Novel epigenetic biomarkers in the diagnosis of minimal residual disease in head and neck cancer.

CANCER RESEARCH UK (UK)

September 2007 - April 2009

Epigenetic biomakers of malignant transformation in oral dysplasia and tumour margins.

BRITISH ASSOCIATION OF ORAL MAXILLOFACIAL SURGEONS (UK)

February 2006 - July 2006

Longitudinal study linking circulating DNA aberrations to prognosis in OSCC.

BRITISH ASSOCIATION OF ORAL MAXILLOFACIAL SURGEONS (UK)

September 2004 - August 2006

Research Collaborations

Professor Peter Weightman

Project: Infrared imaging in the early diagnosis of oral cancer
Internal

A multidisciplinary colloaboration funded by CRUK to investigate the utility of infrared imaging in the early diagnosis of oral cancer

Dr. T. Liloglou

External

Exchange of techniques relating to gene promoter methylation analysis

Dr. AsteriosTriantafyllou

Project: HNSCC
Internal

Histopathological assessment of HNSCC

Dr. Jag Dhanda

Project: The invasive front in HNSCC
External

Development of biomarkers of aggression in HNSCC using diagnostic biopsy tissue

Prof. D.P. Kelsell

External: St Bart's & Royal London School of Medicine & Dentistry

Genetics and skin phenotype in tylosis with oesophageal cancer.

Dr. A. Ellis

External: Royal Liverpool and Broadgreen University Hospital NHS Trust

Collectionof clinical samples for the tylosis project