Photo of Professor David Fernig

Professor David Fernig BSc, PhD

Professor of Biological Chemistry Biochemistry & Systems Biology

    Publications

    2021

    A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U. (Journal article)

    Foulkes, D. M., McLean, K., Zheng, Y., Sarsby, J., Haneef, A. S., Fernig, D. G., . . . Kaye, S. B. (2021). A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U.. The Biochemical journal, 478(3), 647-668. doi:10.1042/bcj20200780

    DOI: 10.1042/bcj20200780

    2020

    Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin (Journal article)

    Mycroft-West, C. J., Su, D., Pagani, I., Rudd, T. R., Elli, S., Gandhi, N. S., . . . Skidmore, M. A. (2020). Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin. THROMBOSIS AND HAEMOSTASIS, 120(12), 1700-1715. doi:10.1055/s-0040-1721319

    DOI: 10.1055/s-0040-1721319

    Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain (Journal article)

    Mycroft-West, C., Su, D., Li, Y., Guimond, S., Rudd, T., Elli, S., . . . Skidmore, M. (2020). Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain. doi:10.1101/2020.04.29.068767

    DOI: 10.1101/2020.04.29.068767

    Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin (Journal article)

    Mycroft-West, C. J., Su, D., Pagani, I., Rudd, T. R., Elli, S., Guimond, S. E., . . . Skidmore, M. A. (n.d.). Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin. doi:10.1101/2020.04.28.066761

    DOI: 10.1101/2020.04.28.066761

    SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins (Journal article)

    Mycroft-West, C., Su, D., Li, Y., Guimond, S., Rudd, T., Elli, S., . . . Skidmore, M. (2020). SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins. doi:10.1101/2020.04.29.068486

    DOI: 10.1101/2020.04.29.068486

    The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding (Journal article)

    Mycroft-West, C., Su, D., Elli, S., Li, Y., Li, Y., Guimond, S., . . . Skidmore, M. (2020). The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding. doi:10.1101/2020.02.29.971093

    DOI: 10.1101/2020.02.29.971093

    SimpleDSFviewer: A tool to analyze and view differential scanning fluorimetry data for characterizing protein thermal stability and interactions (Journal article)

    Sun, C., Li, Y., Yates, E. A., & Fernig, D. G. (2020). SimpleDSFviewer: A tool to analyze and view differential scanning fluorimetry data for characterizing protein thermal stability and interactions. PROTEIN SCIENCE, 29(1), 19-27. doi:10.1002/pro.3703

    DOI: 10.1002/pro.3703

    2019

    The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis (Internet publication)

    Nunes, Q. M., Dunhao, S., Brownridge, P. J., Simpson, D. M., Sun, C., Li, Y., . . . Fernig, D. G. (2019). The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. doi:10.1101/497271

    DOI: 10.1101/497271

    Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections (Journal article)

    Foulkes, D. M., McLean, K., Haneef, A. S., Fernig, D. G., Winstanley, C., Berry, N., & Kaye, S. B. (2019). Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections. MICROORGANISMS, 7(12). doi:10.3390/microorganisms7120707

    DOI: 10.3390/microorganisms7120707

    Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors (Journal article)

    Kershaw, N., Byrne, D., Parsons, H., Berry, N. G., Fernig, D., Eyers, P. A., & Cosstick, R. (n.d.). Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors. doi:10.26434/chemrxiv.9944243

    DOI: 10.26434/chemrxiv.9944243

    Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors (Journal article)

    Kershaw, N., Byrne, D., Parsons, H., Berry, N., Fernig, D., Eyers, P., & Cosstick, R. (2019). Structure-Based Design of Nucleoside-Derived Analogues as Sulfotransferase Inhibitors. RSC Advances: an international journal to further the chemical sciences. doi:10.1039/C9RA07567D

    DOI: 10.1039/C9RA07567D

    Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors (Journal article)

    Kershaw, N. M., Byrne, D. P., Parsons, H., Berry, N. G., Fernig, D. G., Eyers, P. A., & Cosstick, R. (2019). Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors. RSC ADVANCES, 9(55), 32165-32173. doi:10.1039/c9ra07567d

    DOI: 10.1039/c9ra07567d

    Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk (Journal article)

    Nguyen, T., Duchesne, L., Narayana, G. H. N. S., Boggetto, N., Fernig, D. D., Murade, C. U., . . . Mege, R. -M. (2019). Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk. ONCOGENE, 38(35), 6283-6300. doi:10.1038/s41388-019-0875-6

    DOI: 10.1038/s41388-019-0875-6

    Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation (Journal article)

    Sun, C., Liu, M., Sun, P., Yang, M., Yates, E. A., Guo, Z., & Fernig, D. G. (2019). Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation. FEBS OPEN BIO, 9(8), 1477-1487. doi:10.1002/2211-5463.12696

    DOI: 10.1002/2211-5463.12696

    The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis (Journal article)

    Nunes, Q. M., Su, D., Brownridge, P. J., Simpson, D. M., Sun, C., Li, Y., . . . Fernig, D. G. (2019). The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. PLOS ONE, 14(6). doi:10.1371/journal.pone.0217633

    DOI: 10.1371/journal.pone.0217633

    A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the beta Secretase Implicated in Alzheimer's Disease (Journal article)

    Mycroft-West, C. J., Cooper, L. C., Devlin, A. J., Procter, P., Guimond, S. E., Guerrini, M., . . . Skidmore, M. A. (2019). A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the beta Secretase Implicated in Alzheimer's Disease. MARINE DRUGS, 17(5). doi:10.3390/md17050293

    DOI: 10.3390/md17050293

    Inhibition of BACE1, the beta-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus (Journal article)

    Mycroft-West, C. J., Devlin, A. J., Cooper, L. C., Procter, P., Miller, G. J., Fernig, D. G., . . . Skidmore, M. A. (2019). Inhibition of BACE1, the beta-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus. NEURAL REGENERATION RESEARCH, 15(8), 1546-1553. doi:10.4103/1673-5374.274341

    DOI: 10.4103/1673-5374.274341

    Enhanced inhibition of influenza virus infection by peptide-noble-metal nanoparticle conjugates (Journal article)

    Alghrair, Z. K., Fernig, D. G., & Ebrahimi, B. (2019). Enhanced inhibition of influenza virus infection by peptide-noble-metal nanoparticle conjugates. BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 10, 1038-1047. doi:10.3762/bjnano.10.104

    DOI: 10.3762/bjnano.10.104

    Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans (Internet publication)

    Bui, T., Li, Y., Nunes, Q., Wilkinson, M., & Fernig, D. (2019). Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans. doi:10.1101/574947

    DOI: 10.1101/574947

    Corrigendum: A descriptive guide for absolute quantification of produced shRNA pseudotyped lentiviral particles by real-time PCR. (Journal article)

    Mournetas, V., Pereira, S. M., Fernig, D. G., & Murray, P. (2019). Corrigendum: A descriptive guide for absolute quantification of produced shRNA pseudotyped lentiviral particles by real-time PCR.. Journal of biological methods, 6(4), e122. doi:10.14440/jbm.2019.326

    DOI: 10.14440/jbm.2019.326

    2018

    The Heparin-Binding Proteome in Murine Experimental Acute Pancreatitis (Journal article)

    Nunes, Q. M., Su, D., Brownridge, P. J., Sun, C., Li, Y., Huang, W., . . . Fernig, D. G. (2016). The Heparin-Binding Proteome in Murine Experimental Acute Pancreatitis. PANCREAS, 45(10), 1530. Retrieved from http://gateway.webofknowledge.com/

    Highly efficient production of functional recombinant human fibroblast growth factor 22 in E-coli and its protective effects on H2O2-lesioned L02 cells (Journal article)

    Yang, H., Tian, H., Cheng, J., Zheng, J., Wang, D., Sun, C., . . . Jiang, C. (2018). Highly efficient production of functional recombinant human fibroblast growth factor 22 in E-coli and its protective effects on H2O2-lesioned L02 cells. PROTEIN EXPRESSION AND PURIFICATION, 152, 114-121. doi:10.1016/j.pep.2018.04.002

    DOI: 10.1016/j.pep.2018.04.002

    New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors (Journal article)

    Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (2018). New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2417-2433. doi:10.1042/BCJ20180265

    DOI: 10.1042/BCJ20180265

    New tools for carbohydrate sulphation analysis: Heparan Sulphate 2-O-sulphotranserase (HS2ST) is a target for small molecule protein kinase inhibitors (Journal article)

    Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (n.d.). New tools for carbohydrate sulphation analysis: Heparan Sulphate 2-O-sulphotranserase (HS2ST) is a target for small molecule protein kinase inhibitors. doi:10.1101/296533

    DOI: 10.1101/296533

    New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors (Journal article)

    Byrne, D. P., Li, Y., Ngamlert, P., Ramakrishnan, K., Eyers, C. E., Wells, C., . . . Eyers, P. A. (2018). New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2435-2455. doi:10.1042/BCJ20180266

    DOI: 10.1042/BCJ20180266

    Biocompatible Peptide-Coated Ultrasmall Superparamagnetic Iron Oxide Nanoparticles for In Vivo Contrast-Enhanced Magnetic Resonance Imaging (Journal article)

    Chee, H. L., Gan, C. R. R., Ng, M., Low, L., Fernig, D. G., Bhakoo, K. K., & Paramelle, D. (2018). Biocompatible Peptide-Coated Ultrasmall Superparamagnetic Iron Oxide Nanoparticles for In Vivo Contrast-Enhanced Magnetic Resonance Imaging. ACS Nano, 12(7), 6480-6491. doi:10.1021/acsnano.7b07572

    DOI: 10.1021/acsnano.7b07572

    Enhanced inhibition of influenza virus infection by peptide-noble metal nanoparticle conjugates (Journal article)

    Alghrair, Z., Fernig, D., & Ebrahimi, B. (2018). Enhanced inhibition of influenza virus infection by peptide-noble metal nanoparticle conjugates. doi:10.1101/324939

    DOI: 10.1101/324939

    Functional examination of novel kisspeptin phosphinic peptides (Journal article)

    Zhang, X., Matziari, M., Xie, Y., Fernig, D., Rong, R., Meng, J., & Lu, Z. -L. (2018). Functional examination of novel kisspeptin phosphinic peptides. PLOS ONE, 13(4). doi:10.1371/journal.pone.0195089

    DOI: 10.1371/journal.pone.0195089

    Large-Scale Expression, Purification of Bioactive Recombinant Human FGF6 in E-coli and the Mechanisms of Its Myocardial Protection (Journal article)

    Zheng, J., Wang, S., Yang, H., Chen, Z., Huang, S., Zhao, T., . . . Tian, H. (2018). Large-Scale Expression, Purification of Bioactive Recombinant Human FGF6 in E-coli and the Mechanisms of Its Myocardial Protection. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 24(1), 105-115. doi:10.1007/s10989-017-9592-6

    DOI: 10.1007/s10989-017-9592-6

    2017

    Expression and purification of an FGF9 fusion protein in E-coli, and the effects of the FGF9 subfamily on human hepatocellular carcinoma cell proliferation and migration (Journal article)

    Wang, S., Lin, H., Zhao, T., Huang, S., Fernig, D. G., Xu, N., . . . Tian, H. (2017). Expression and purification of an FGF9 fusion protein in E-coli, and the effects of the FGF9 subfamily on human hepatocellular carcinoma cell proliferation and migration. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 101(21), 7823-7835. doi:10.1007/s00253-017-8468-1

    DOI: 10.1007/s00253-017-8468-1

    2016

    High colloidal stability of gold nanorods coated with a peptide-ethylene glycol: Analysis by cyanide-mediated etching and nanoparticle tracking analysis (Journal article)

    Free, P., Conger, G., Siji, W., Zhang, J. B., & Fernig, D. G. (2016). High colloidal stability of gold nanorods coated with a peptide-ethylene glycol: Analysis by cyanide-mediated etching and nanoparticle tracking analysis. Colloids and Surfaces B: Biointerfaces, 146, 871-878. doi:10.1016/j.colsurfb.2016.07.006

    DOI: 10.1016/j.colsurfb.2016.07.006

    Specific Internalisation of Gold Nanoparticles into Engineered Porous Protein Cages via Affinity Binding (Journal article)

    Paramelle, D., Peng, T., Free, P., Fernig, D. G., Lim, S., & Tomczak, N. (2016). Specific Internalisation of Gold Nanoparticles into Engineered Porous Protein Cages via Affinity Binding. PLOS ONE, 11(9). doi:10.1371/journal.pone.0162848

    DOI: 10.1371/journal.pone.0162848

    Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and-2 alpha impacts on their stability and mobility (Journal article)

    Taylor, S. E., Bagnall, J., Mason, D., Levy, R., Fernig, D. G., & See, V. (2016). Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and-2 alpha impacts on their stability and mobility. OPEN BIOLOGY, 6(9). doi:10.1098/rsob.160195

    DOI: 10.1098/rsob.160195

    A descriptive guide for absolute quantification of produced shRNA pseudotyped lentiviral particles by real-time PCR. (Journal article)

    Mournetas, V., Pereira, S. M., Fernig, D. G., & Murray, P. (2016). A descriptive guide for absolute quantification of produced shRNA pseudotyped lentiviral particles by real-time PCR.. Journal of biological methods, 3(4), e55. doi:10.14440/jbm.2016.142

    DOI: 10.14440/jbm.2016.142

    High production in E-coli of biologically active recombinant human fibroblast growth factor 20 and its neuroprotective effects (Journal article)

    Tian, H., Zhao, Y., Chen, N., Wu, M., Gong, W., Zheng, J., . . . Jiang, C. (2016). High production in E-coli of biologically active recombinant human fibroblast growth factor 20 and its neuroprotective effects. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 100(7), 3023-3034. doi:10.1007/s00253-015-7168-y

    DOI: 10.1007/s00253-015-7168-y

    Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification (Journal article)

    Li, Y., Sun, C., Yates, E. A., Jiang, C., Wilkinson, M. C., & Fernig, D. G. (2016). Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification. Open Biology, 6(3). doi:10.1098/rsob.150275

    DOI: 10.1098/rsob.150275

    Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix. (Journal article)

    Sun, C., Marcello, M., Li, Y., Mason, D., Levy, R., & Fernig, D. G. (2016). Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix. OPEN BIOLOGY, 6(03), 17 pages. doi:10.1098/rsob.150277

    DOI: 10.1098/rsob.150277

    In silico analyses of heparin binding proteins expression in human periodontal tissues. (Journal article)

    Lackey, B., Nunes, Q. M., Higham, S. M., Fernig, D. G., & Valappil, S. P. (2016). In silico analyses of heparin binding proteins expression in human periodontal tissues.. BMC research notes, 9, 53. doi:10.1186/s13104-016-1857-1

    DOI: 10.1186/s13104-016-1857-1

    Fibroblast growth factors as tissue repair and regeneration therapeutics (Journal article)

    Nunes, Q. M., Li, Y., Sun, C., Kinnunen, T. K., & Fernig, D. G. (2016). Fibroblast growth factors as tissue repair and regeneration therapeutics. PEERJ, 4. doi:10.7717/peerj.1535

    DOI: 10.7717/peerj.1535

    2015

    Structural determinants of heparin-transforming growth factor-beta 1 interactions and their effects on signaling (Journal article)

    Lee, J., Wee, S., Gunaratne, J., Chua, R. J. E., Smith, R. A. A., Ling, L., . . . Cool, S. M. (2015). Structural determinants of heparin-transforming growth factor-beta 1 interactions and their effects on signaling. GLYCOBIOLOGY, 25(12), 1491-1504. doi:10.1093/glycob/cwv064

    DOI: 10.1093/glycob/cwv064

    Cytokines and growth factors cross-link heparan sulfate (Journal article)

    Migliorini, E., Thakar, D., Kuehnle, J., Sadir, R., Dyer, D. P., Li, Y., . . . Richter, R. P. (2015). Cytokines and growth factors cross-link heparan sulfate. OPEN BIOLOGY, 5(8). doi:10.1098/rsob.150046

    DOI: 10.1098/rsob.150046

    HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors (Journal article)

    Sun, C., Li, Y., Taylor, S. E., Mao, X., Wilkinson, M. C., & Fernig, D. G. (2015). HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors. PEERJ, 3. doi:10.7717/peerj.1060

    DOI: 10.7717/peerj.1060

    Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells (Journal article)

    Nieves, D., Li, Y., Fernig, D., & Levy, R. (2015). Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells. Royal Society Open Science, 2. doi:10.1098/rsos.140454

    DOI: 10.1098/rsos.140454

    Targeting Cell Membrane Lipid Rafts by Stoichiometric Functionalization of Gold Nanoparticles with a Sphingolipid-Binding Domain Peptide (Journal article)

    Paramelle, D., Nieves, D., Brun, B., Kraut, R. S., & Fernig, D. (2015). Targeting Cell Membrane Lipid Rafts by Stoichiometric Functionalization of Gold Nanoparticles with a Sphingolipid-Binding Domain Peptide. Advanced Healthcare Materials, 4(6), 911-917. doi:10.1002/adhm.201400730

    DOI: 10.1002/adhm.201400730

    Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism (Journal article)

    Hughes, A. J., Rudd, T. R., Wright, G. S. A., Fernig, D. G., Siligardi, G., & Yates, E. A. (2015). Detection of interaction between protein trytophan residues and small or macromolecular ligands by synchrotron radiation magnetic circular dichroism. ANALYTICAL METHODS, 7(5), 1667-1671. doi:10.1039/c4ay02618g

    DOI: 10.1039/c4ay02618g

    2014

    Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide (Journal article)

    Dos Santos, C., Blanc, C., Elahouel, R., Prescott, M., Carpentier, G., Ori, A., . . . Delbé, J. (2014). Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide. Biochimie, 107, 350-357. doi:10.1016/j.biochi.2014.10.002

    DOI: 10.1016/j.biochi.2014.10.002

    Partial mitigation of gold nanoparticle-interactions with human lymphocytes by surface functionalization with a 'mixed-matrix' (Journal article)

    Liptrott, N. J., Kendall, E., Nieves, D. J., Farrell, J., Rannard, S., Fernig, D. G., & Owen, A. (2014). Partial mitigation of gold nanoparticle-interactions with human lymphocytes by surface functionalization with a 'mixed-matrix'. Nanomedicine, 9(16), 2467-2479. doi:10.2217/nnm.14.38

    DOI: 10.2217/nnm.14.38

    Network based meta-analysis prediction of microenvironmental relays involved in stemness of human embryonic stem cells (Journal article)

    Mournetas, V., Nunes, Q., Murray, P., Sanderson, C., & Fernig, D. (2014). Network based meta-analysis prediction of microenvironmental relays involved in stemness of human embryonic stem cells. PeerJ, 2. doi:10.7717/peerj.618

    DOI: 10.7717/peerj.618

    A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra (Journal article)

    Paramelle, D., Sadovoy, A., Gorelik, S., Free, P., Hobley, J., & Fernig, D. G. (2014). A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra. Analyst, 139(19), 4855-4861. doi:10.1039/c4an00978a

    DOI: 10.1039/c4an00978a

    Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry (Journal article)

    Nieves, D., Azmi, N., Xu, R., Levy, R., Yates, E., & Fernig, D. (2014). Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry. Chemical Communications, 50(86), 13157-13160. doi:10.1039/c4cc05909c

    DOI: 10.1039/c4cc05909c

    Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars (Journal article)

    Uniewicz, K. A., Ori, A., Ahmed, Y. A., Yates, E. A., & Fernig, D. G. (2014). Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars. PEERJ, 2. doi:10.7717/peerj.461

    DOI: 10.7717/peerj.461

    Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a 'mixed matrix' (Journal article)

    Liptrott, N. J., Kendall, E., Nieves, D. J., Farrell, J., Rannard, S., Fernig, D. G., & Owen, A. (2014). Partial mitigation of gold nanoparticle interactions with human lymphocytes by surface functionalization with a 'mixed matrix'. Nanomedicine (London).

    2013

    S-Layer Proteins (Chapter)

    S-Layer Proteins (2013). In Handbook of Biofunctional Surfaces (pp. 540-602). Jenny Stanford Publishing. doi:10.1201/b14900-21

    DOI: 10.1201/b14900-21

    Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network (Journal article)

    Xu, R., Rudd, T. R., Hughes, A. J., Siligardi, G., Fernig, D. G., & Yates, E. A. (2013). Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network. FEBS JOURNAL, 280(10), 2260-2270. doi:10.1111/febs.12201

    DOI: 10.1111/febs.12201

    The heparin-binding protein interactome in pancreatic diseases (Journal article)

    Nunes, Q. M., Mournetas, V., Lane, B., Sutton, R., Fernig, D. G., & Vasieva, O. (2013). The heparin-binding protein interactome in pancreatic diseases. PANCREATOLOGY, 13(6), 598-604. doi:10.1016/j.pan.2013.08.004

    DOI: 10.1016/j.pan.2013.08.004

    2012

    Diversification of the Structural Determinants of Fibroblast Growth Factor-Heparin Interactions IMPLICATIONS FOR BINDING SPECIFICITY (Journal article)

    Xu, R., Ori, A., Rudd, T. R., Uniewicz, K. A., Ahmed, Y. A., Guimond, S. E., . . . Fernig, D. G. (2012). Diversification of the Structural Determinants of Fibroblast Growth Factor-Heparin Interactions IMPLICATIONS FOR BINDING SPECIFICITY. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(47). doi:10.1074/jbc.M112.398826

    DOI: 10.1074/jbc.M112.398826

    Glycans: pervasive regulators of protein and cellular function Editorial overview (Journal article)

    Fernig, D., & Boraston, A. B. (2012). Glycans: pervasive regulators of protein and cellular function Editorial overview. CURRENT OPINION IN STRUCTURAL BIOLOGY, 22(5), 537-539. doi:10.1016/j.sbi.2012.09.003

    DOI: 10.1016/j.sbi.2012.09.003

    Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate (Journal article)

    Duchesne, L., Octeau, V., Bearon, R. N., Beckett, A., Prior, I. A., Lounis, B., & Fernig, D. G. (2012). Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate. PLOS BIOLOGY, 10(7). doi:10.1371/journal.pbio.1001361

    DOI: 10.1371/journal.pbio.1001361

    ChemInform Abstract: Long-Term Tracking of Cells Using Inorganic Nanoparticles as Contrast Agents: Are We There Yet? (Journal article)

    Taylor, A., Wilson, K. M., Murray, P., Fernig, D. G., & Levy, R. (2012). ChemInform Abstract: Long-Term Tracking of Cells Using Inorganic Nanoparticles as Contrast Agents: Are We There Yet?. ChemInform, 43(27), no. doi:10.1002/chin.201227266

    DOI: 10.1002/chin.201227266

    Fundamental differences in model cell-surface polysaccharides revealed by complementary optical and spectroscopic techniques (Journal article)

    Holder, G. M., Bowfield, A., Surman, M., Suepfle, M., Moss, D., Tucker, C., . . . Weightman, P. (2012). Fundamental differences in model cell-surface polysaccharides revealed by complementary optical and spectroscopic techniques. SOFT MATTER, 8(24), 6521-6527. doi:10.1039/c2sm25239b

    DOI: 10.1039/c2sm25239b

    Array-Based Functional Screening of Heparin Glycans (Journal article)

    Puvirajesinghe, T. M., Ahmed, Y. A., Powell, A. K., Fernig, D. G., Guimond, S. E., & Turnbull, J. E. (2012). Array-Based Functional Screening of Heparin Glycans. CHEMISTRY & BIOLOGY, 19(5), 553-558. doi:10.1016/j.chembiol.2012.03.011

    DOI: 10.1016/j.chembiol.2012.03.011

    S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration (Journal article)

    Du, M., Wang, G., Ismail, T. M., Gross, S., Fernig, D. G., Barraclough, R., & Rudland, P. S. (2012). S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(19), 15330-15344. doi:10.1074/jbc.M112.349787

    DOI: 10.1074/jbc.M112.349787

    S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration* (Journal article)

    Du, M., Wang, G., Ismail, T. M., Gross, S., Fernig, D. G., Barraclough, R., & Rudland, P. S. (2012). S100P Dissociates Myosin IIA Filaments and Focal Adhesion Sites to Reduce Cell Adhesion and Enhance Cell Migration*. Journal of Biological Chemistry, 287(19), 15330-15344. doi:10.1074/jbc.m112.349787

    DOI: 10.1074/jbc.m112.349787

    ANG-1 TIE-2 and BMPR Signalling Defects Are Not Seen in the Nitrofen Model of Pulmonary Hypertension and Congenital Diaphragmatic Hernia (Journal article)

    Corbett, H. J., Connell, M. G., Fernig, D. G., Losty, P. D., & Jesudason, E. C. (2012). ANG-1 TIE-2 and BMPR Signalling Defects Are Not Seen in the Nitrofen Model of Pulmonary Hypertension and Congenital Diaphragmatic Hernia. PLOS ONE, 7(4). doi:10.1371/journal.pone.0035364

    DOI: 10.1371/journal.pone.0035364

    Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet? (Journal article)

    Taylor, A., Wilson, K. M., Murray, P., Fernig, D. G., & Levy, R. (2012). Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?. CHEMICAL SOCIETY REVIEWS, 41(7), 2707-2717. doi:10.1039/c2cs35031a

    DOI: 10.1039/c2cs35031a

    Features of Thiolated Ligands Promoting Resistance to Ligand Exchange in Self-Assembled Monolayers on Gold Nanoparticles (Journal article)

    Chen, X., Qoutah, W. W., Free, P., Hobley, J., Fernig, D. G., & Paramelle, D. (2012). Features of Thiolated Ligands Promoting Resistance to Ligand Exchange in Self-Assembled Monolayers on Gold Nanoparticles. AUSTRALIAN JOURNAL OF CHEMISTRY, 65(3), 266-274. doi:10.1071/CH11432

    DOI: 10.1071/CH11432

    Synthesis of Silver Nanoparticles with Monovalently Functionalized Self-Assembled Monolayers (Journal article)

    Free, P., Paramelle, D., Bosman, M., Hobley, J., & Fernig, D. G. (2012). Synthesis of Silver Nanoparticles with Monovalently Functionalized Self-Assembled Monolayers. AUSTRALIAN JOURNAL OF CHEMISTRY, 65(3), 275-282. doi:10.1071/CH11429

    DOI: 10.1071/CH11429

    Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry. (Journal article)

    Uniewicz, K. A., Ori, A., Rudd, T. R., Guerrini, M., Wilkinson, M. C., Fernig, D. G., & Yates, E. A. (2012). Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry.. Methods in molecular biology (Clifton, N.J.), 836, 171-182. doi:10.1007/978-1-61779-498-8_12

    DOI: 10.1007/978-1-61779-498-8_12

    Photothermal Laser Material Interactions - From the Sledgehammer to Nano-GPS (Conference Paper)

    Hobley, J., Paramelle, D., Free, P., Fernig, D. G., Kajimoto, S., & Gorelik, S. (2012). Photothermal Laser Material Interactions - From the Sledgehammer to Nano-GPS. In ADVANCES IN BIO-IMAGING: FROM PHYSICS TO SIGNAL UNDERSTANDING ISSUES Vol. 120 (pp. 85-111). Retrieved from http://gateway.webofknowledge.com/

    Single Molecule Imaging with Stable 6 NM Quantum Dots (Conference Paper)

    Cai, E., Wilson, K., Ge, P., Tjioe, M., Fernig, D. G., & Selvin, P. R. (2012). Single Molecule Imaging with Stable 6 NM Quantum Dots. In BIOPHYSICAL JOURNAL Vol. 102 (pp. 182A). doi:10.1016/j.bpj.2011.11.990

    DOI: 10.1016/j.bpj.2011.11.990

    ANG-1 TIE-2 and BMPR Signalling Defects Are Not Seen in the Nitrofen Model of Pulmonary Hypertension and Congenital Diaphragmatic Hernia (Journal article)

    Corbett, H. J., Connell, M. G., Fernig, D. G., Losty, P. D., & Jesudason, E. C. (n.d.). ANG-1 TIE-2 and BMPR Signalling Defects Are Not Seen in the Nitrofen Model of Pulmonary Hypertension and Congenital Diaphragmatic Hernia. PLoS ONE, 7(4), e35364. doi:10.1371/journal.pone.0035364

    DOI: 10.1371/journal.pone.0035364

    Ordering and motional characteristics of extracellular matrix polysaccharides revealed by complementary optical and spectroscopic techniques (Journal article)

    Holder, G. M., Bowfield, A., Surman, M., Suepfle, M., Moss, D., Rudd, T. R., . . . Weightman, P. (2012). Ordering and motional characteristics of extracellular matrix polysaccharides revealed by complementary optical and spectroscopic techniques. Soft Matter, 8, 6521.

    2011

    Gold nanoparticles as advanced building blocks for nanoscale self-assembled systems (Journal article)

    Shaw, C. P., Fernig, D. G., & Levy, R. (2011). Gold nanoparticles as advanced building blocks for nanoscale self-assembled systems. JOURNAL OF MATERIALS CHEMISTRY, 21(33), 12181-12187. doi:10.1039/c1jm11945a

    DOI: 10.1039/c1jm11945a

    Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation? (Journal article)

    Thompson, S. M., Connell, M. G., van Kuppevelt, T. H., Xu, R., Turnbull, J. E., Losty, P. D., . . . Jesudason, E. C. (2011). Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation?. BMC developmental biology, 11, 38. doi:10.1186/1471-213x-11-38

    DOI: 10.1186/1471-213x-11-38

    A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome (Journal article)

    Ori, A., Wilkinson, M. C., & Fernig, D. G. (2011). A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(22), 19892-19904. doi:10.1074/jbc.M111.228114

    DOI: 10.1074/jbc.M111.228114

    A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome (Journal article)

    Ori, A., Wilkinson, M. C., & Fernig, D. G. (2011). A Systems Biology Approach for the Investigation of the Heparin/Heparan Sulfate Interactome. Journal of Biological Chemistry, 286(22), 19892-19904. doi:10.1074/jbc.m111.228114

    DOI: 10.1074/jbc.m111.228114

    Large Conductance Changes in Peptide Single Molecule Junctions Controlled by pH (Journal article)

    Scullion, L., Doneux, T., Bouffier, L., Fernig, D. G., Higgins, S. J., Bethell, D., & Nichols, R. J. (2011). Large Conductance Changes in Peptide Single Molecule Junctions Controlled by pH. JOURNAL OF PHYSICAL CHEMISTRY C, 115(16), 8361-8368. doi:10.1021/jp201222b

    DOI: 10.1021/jp201222b

    The Cooperation of FGF Receptor and Klotho Is Involved in Excretory Canal Development and Regulation of Metabolic Homeostasis in Caenorhabditis elegans (Journal article)

    Polanska, U. M., Edwards, E., Fernig, D. G., & Kinnunen, T. K. (2011). The Cooperation of FGF Receptor and Klotho Is Involved in Excretory Canal Development and Regulation of Metabolic Homeostasis in Caenorhabditis elegans. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(7), 5657-5666. doi:10.1074/jbc.M110.173039

    DOI: 10.1074/jbc.M110.173039

    Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis (Journal article)

    Uniewicz, K. A., Cross, M. J., & Fernig, D. G. (2011). Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(1), 12-23. doi:10.1074/jbc.M110.190801

    DOI: 10.1074/jbc.M110.190801

    2010

    Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships (Journal article)

    Rudd, T. R., Uniewicz, K. A., Ori, A., Guimond, S. E., Skidmore, M. A., Gaudesi, D., . . . Yates, E. A. (2010). Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. ORGANIC & BIOMOLECULAR CHEMISTRY, 8(23), 5390-5397. doi:10.1039/c0ob00246a

    DOI: 10.1039/c0ob00246a

    Bipartite Design of a Self-Fibrillating Protein Copolymer with Nanopatterned Peptide Display Capabilities (Journal article)

    Bruning, M., Kreplak, L., Leopoldseder, S., Mueller, S. A., Ringler, P., Duchesne, L., . . . Mayans, O. (2010). Bipartite Design of a Self-Fibrillating Protein Copolymer with Nanopatterned Peptide Display Capabilities. NANO LETTERS, 10(11), 4533-4537. doi:10.1021/nl1024886

    DOI: 10.1021/nl1024886

    The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor (Journal article)

    Zhu, H., Duchesne, L., Rudland, P. S., & Fernig, D. G. (2010). The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor. CELL COMMUNICATION AND SIGNALING, 8. doi:10.1186/1478-811X-8-14

    DOI: 10.1186/1478-811X-8-14

    Prevention of surface reconstruction at the Au(110)/electrolyte interface by the adsorption of cytosine (Journal article)

    Mansley, C. P., Smith, C. I., Bowfield, A., Fernig, D. G., Edwards, C., & Weightman, P. (2010). Prevention of surface reconstruction at the Au(110)/electrolyte interface by the adsorption of cytosine. JOURNAL OF CHEMICAL PHYSICS, 132(21). doi:10.1063/1.3436715

    DOI: 10.1063/1.3436715

    Differential Scanning Fluorimetry Measurement of Protein Stability Changes upon Binding to Glycosaminoglycans: A Screening Test for Binding Specificity (Journal article)

    Uniewicz, K. A., Ori, A., Xu, R., Ahmed, Y., Wilkinson, M. C., Fernig, D. G., & Yates, E. A. (2010). Differential Scanning Fluorimetry Measurement of Protein Stability Changes upon Binding to Glycosaminoglycans: A Screening Test for Binding Specificity. ANALYTICAL CHEMISTRY, 82(9), 3796-3802. doi:10.1021/ac100188x

    DOI: 10.1021/ac100188x

    Heparan Sulfate in Lung Morphogenesis: The Elephant in the Room (Journal article)

    Thompson, S. M., Jesudason, E. C., Turnbull, J. E., & Fernig, D. G. (2010). Heparan Sulfate in Lung Morphogenesis: The Elephant in the Room. BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS, 90(1), 32-44. doi:10.1002/bdrc.20169

    DOI: 10.1002/bdrc.20169

    Self-association of Calcium-binding Protein S100A4 and Metastasis (Journal article)

    Ismail, T. M., Zhang, S., Fernig, D. G., Gross, S., Martin-Fernandez, M. L., See, V., . . . Barraclough, R. (2010). Self-association of Calcium-binding Protein S100A4 and Metastasis. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(2), 914-922. doi:10.1074/jbc.M109.010892

    DOI: 10.1074/jbc.M109.010892

    Self-association of Calcium-binding Protein S100A4 and Metastasis* (Journal article)

    Ismail, T. M., Zhang, S., Fernig, D. G., Gross, S., Martin-Fernandez, M. L., See, V., . . . Barraclough, R. (2010). Self-association of Calcium-binding Protein S100A4 and Metastasis*. Journal of Biological Chemistry, 285(2), 914-922. doi:10.1074/jbc.m109.010892

    DOI: 10.1074/jbc.m109.010892

    'Differential Scanning Fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a rapid screening test for binding specificity' (Journal article)

    Uniewicz, K. A., Ori, A., Xu, R., Ahmed, Y., Fernig, D. G., & Yates, E. A. (2010). 'Differential Scanning Fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a rapid screening test for binding specificity'. Analytical Chemistry, 82, 3796-3802.

    Bipartite design of a self-assembled protein filament with nanopatterned peptide display capabilities (Journal article)

    Bruning, M., Kreplak, L., Leopoldseder, S., Müller, S. A., Ringler, P., Duchesne, L., . . . Mayans, O. (2010). Bipartite design of a self-assembled protein filament with nanopatterned peptide display capabilities. Nano Letters, 10, 4533-4537.

    Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships (Journal article)

    Rudd, T. R., Uniewicz, K. A., Ori, A., Guimond, S. E., Skidmore, M. A., Gaudesi, D., . . . Yates, E. A. (2010). Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships. Organic & Biomolecular Chemistry, 8(23), 5390. doi:10.1039/c0ob00246a

    DOI: 10.1039/c0ob00246a

    Intracellular Delivery and Fate of Peptide-Capped Gold Nanoparticles (Conference Paper)

    Cesbron, Y., See, V., Free, P., Nativo, P., Shaheen, U., Rigden, D. J., . . . Levy, R. (2010). Intracellular Delivery and Fate of Peptide-Capped Gold Nanoparticles. In BIOPHYSICAL JOURNAL Vol. 98 (pp. 203A). doi:10.1016/j.bpj.2009.12.1081

    DOI: 10.1016/j.bpj.2009.12.1081

    Prevention of surface reconstruction at the Au(110)/electrolyte interface by the adsorption of cytosine (Journal article)

    Mansley, C. P., Smith, C. I., Bowfield, A., Fernig, D. G., Edwards, C., & Weightman, P. (2010). Prevention of surface reconstruction at the Au(110)/electrolyte interface by the adsorption of cytosine. The Journal of Chemical Physics, 132, 214708.

    2009

    Heparan Sulfate Phage Display Antibodies Identify Distinct Epitopes with Complex Binding Characteristics INSIGHTS INTO PROTEIN BINDING SPECIFICITIES (Journal article)

    Thompson, S. M., Fernig, D. G., Jesudason, E. C., Losty, P. D., van de Westerlo, E. M. A., van Kuppevelt, T. H., & Turnbull, J. E. (2009). Heparan Sulfate Phage Display Antibodies Identify Distinct Epitopes with Complex Binding Characteristics INSIGHTS INTO PROTEIN BINDING SPECIFICITIES. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(51), 35621-35631. doi:10.1074/jbc.M109.009712

    DOI: 10.1074/jbc.M109.009712

    DETECTION OF ANTIMYCOLIC ACID ANTIBODIES BY LIPOSOMAL BIOSENSORS (Journal article)

    Lemmer, Y., Thanyani, S. T., Vrey, P. J., Driver, C. H. S., Venter, L., van Wyngaardt, S., . . . Verschoor, J. A. (2009). DETECTION OF ANTIMYCOLIC ACID ANTIBODIES BY LIPOSOMAL BIOSENSORS. METHODS IN ENZYMOLOGY; LIPOSOMES, PT F, 464, 79-104. doi:10.1016/S0076-6879(09)64005-2

    DOI: 10.1016/S0076-6879(09)64005-2

    Identification of Heparin-binding Sites in Proteins by Selective Labeling (Journal article)

    Ori, A., Free, P., Courty, J., Wilkinson, M. C., & Fernig, D. G. (2009). Identification of Heparin-binding Sites in Proteins by Selective Labeling. MOLECULAR & CELLULAR PROTEOMICS, 8(10), 2256-2265. doi:10.1074/mcp.M900031-MCP200

    DOI: 10.1074/mcp.M900031-MCP200

    N-Glycosylation Regulates Fibroblast Growth Factor Receptor/EGL-15 Activity in Caenorhabditis elegans in Vivo (Journal article)

    Polanska, U. M., Duchesne, L., Harries, J. C., Fernig, D. G., & Kinnunen, T. K. (2009). N-Glycosylation Regulates Fibroblast Growth Factor Receptor/EGL-15 Activity in Caenorhabditis elegans in Vivo. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(48), 33030-33039. doi:10.1074/jbc.M109.058925

    DOI: 10.1074/jbc.M109.058925

    The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids (Journal article)

    Rudd, T. R., Skidmore, M. A., Guimond, S. E., Holman, J., Turnbull, J. E., Lauder, R. M., . . . Yates, E. A. (2009). The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids. THROMBOSIS AND HAEMOSTASIS, 102(5), 874-878. doi:10.1160/TH08-12-0797

    DOI: 10.1160/TH08-12-0797

    The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids (Journal article)

    Guimond, S., Holman, J., Turnbull, J., Lauder, R., Fernig, D., Rudd, T., . . . Yates, E. (2009). The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids. Thrombosis and Haemostasis, 102(11), 874-878. doi:10.1160/th08-12-0797

    DOI: 10.1160/th08-12-0797

    Cathepsin L Digestion of Nanobioconjugates upon Endocytosis (Journal article)

    See, V., Free, P., Cesbron, Y., Nativo, P., Shaheen, U., Rigden, D. J., . . . Levy, R. (2009). Cathepsin L Digestion of Nanobioconjugates upon Endocytosis. ACS NANO, 3(9), 2461-2468. doi:10.1021/nn9006994

    DOI: 10.1021/nn9006994

    Evaluation of biosensor surfaces for the detection of microtubule perturbation (Journal article)

    Daghestani, H. N., Fernig, D. G., & Day, B. W. (2009). Evaluation of biosensor surfaces for the detection of microtubule perturbation. BIOSENSORS & BIOELECTRONICS, 25(1), 136-141. doi:10.1016/j.bios.2009.06.014

    DOI: 10.1016/j.bios.2009.06.014

    Facile synthesis of stable, water-soluble magnetic CoPt hollow nanostructures assisted by multi-thiol ligands (Journal article)

    Lu, L. T., Tung, L. D., Long, J., Fernig, D. G., & Thanh, N. T. K. (2009). Facile synthesis of stable, water-soluble magnetic CoPt hollow nanostructures assisted by multi-thiol ligands. JOURNAL OF MATERIALS CHEMISTRY, 19(33), 6023-6028. doi:10.1039/b906839b

    DOI: 10.1039/b906839b

    Two Mass Spectrometry Based Approaches for the Investigation of the Heparin Interactome (Conference Paper)

    Ori, A., Wilkinson, M. C., & Fernig, D. G. (2009). Two Mass Spectrometry Based Approaches for the Investigation of the Heparin Interactome. In MOLECULAR & CELLULAR PROTEOMICS (pp. S35). Retrieved from http://gateway.webofknowledge.com/

    Cations Modulate Polysaccharide Structure To Determine FGF-FGFR Signaling: A Comparison of Signaling and Inhibitory Polysaccharide Interactions with FGF-1 in Solution (Journal article)

    Guimond, S. E., Rudd, T. R., Skidmore, M. A., Ori, A., Gaudesi, D., Cosentino, C., . . . Yates, E. A. (2009). Cations Modulate Polysaccharide Structure To Determine FGF-FGFR Signaling: A Comparison of Signaling and Inhibitory Polysaccharide Interactions with FGF-1 in Solution. BIOCHEMISTRY, 48(22), 4772-4779. doi:10.1021/bi802318z

    DOI: 10.1021/bi802318z

    Fabrication of Carbohydrate Surfaces by Using Nonderivatised Oligosaccharides, and their Application to Measuring the Assembly of Sugar-Protein Complexes (Journal article)

    Popplewell, J. F., Swann, M. J., Ahmed, Y., Turnbull, J. E., & Fernig, D. G. (2009). Fabrication of Carbohydrate Surfaces by Using Nonderivatised Oligosaccharides, and their Application to Measuring the Assembly of Sugar-Protein Complexes. CHEMBIOCHEM, 10(7), 1218-1226. doi:10.1002/cbic.200800696

    DOI: 10.1002/cbic.200800696

    Fabrication of water-soluble magnetic nanoparticles by ligand-exchange with thermo-responsive polymers (Journal article)

    Robinson, I., Alexander, C., Tung, L. D., Fernig, D. G., & Thanh, N. T. K. (2009). Fabrication of water-soluble magnetic nanoparticles by ligand-exchange with thermo-responsive polymers. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 321(10), 1421-1423. doi:10.1016/j.jmmm.2009.02.055

    DOI: 10.1016/j.jmmm.2009.02.055

    Fabrication of water-soluble magnetic nanoparticles by ligand-exchange with thermo-responsive polymers (Journal article)

    Robinson, I., Alexander, C., Tung, L. D., Fernig, D. G., & Thanh, N. T. K. (2009). Fabrication of water-soluble magnetic nanoparticles by ligand-exchange with thermo-responsive polymers. Journal of Magnetism and Magnetic Materials, 321(10), 1421-1423. doi:10.1016/j.jmmm.2009.02.055

    DOI: 10.1016/j.jmmm.2009.02.055

    Molecular Dynamics and Electrochemical Investigations of a pH-Responsive Peptide Monolayer (Journal article)

    Doneux, T., Bouffier, L., Mello, L. V., Rigden, D. J., Kejnovska, I., Fernig, D. G., . . . Nichols, R. J. (2009). Molecular Dynamics and Electrochemical Investigations of a pH-Responsive Peptide Monolayer. JOURNAL OF PHYSICAL CHEMISTRY C, 113(16), 6792-6799. doi:10.1021/jp810859k

    DOI: 10.1021/jp810859k

    Photothermal Absorption Correlation Spectroscopy (Journal article)

    Octeau, V., Cognet, L., Duchesne, L., Lasne, D., Schaeffer, N., Fernig, D. G., & Lounis, B. (2009). Photothermal Absorption Correlation Spectroscopy. ACS NANO, 3(2), 345-350. doi:10.1021/nn800771m

    DOI: 10.1021/nn800771m

    Extracellular Interactome of the FGF Receptor-Ligand System: Complexities and the Relative Simplicity of the Worm (Journal article)

    Polanska, U. M., Fernig, D. G., & Kinnunen, T. (2009). Extracellular Interactome of the FGF Receptor-Ligand System: Complexities and the Relative Simplicity of the Worm. DEVELOPMENTAL DYNAMICS, 238(2), 277-293. doi:10.1002/dvdy.21757

    DOI: 10.1002/dvdy.21757

    Determination of the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces using reflection anisotropy spectroscopy (Journal article)

    Smith, C. I., Bowfield, A., Dolan, G. J., Cuquerella, M. C., Mansley, C. P., Fernig, D. G., . . . Weightman, P. (2009). Determination of the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces using reflection anisotropy spectroscopy. JOURNAL OF CHEMICAL PHYSICS, 130(4). doi:10.1063/1.3062840

    DOI: 10.1063/1.3062840

    'Determination of the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces using reflection anisotropy spectroscopy' (Journal article)

    Smith, C. I., Bowfield, A., Dolan, G. J., Cuquerella, M. C., Mansley, C. P., Fernig, D. G., . . . Weightman, P. (2009). 'Determination of the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces using reflection anisotropy spectroscopy'. Journal of Chemical Physics, 130(4), 044702.

    Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy (Journal article)

    Smith, C. I., Bowfield, A., Cuquerella, M. C., Mansley, C. P., Farrell, T., Harrison, P., . . . Weightman, P. (2009). Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy. EPL, 85(1). doi:10.1209/0295-5075/85/18006

    DOI: 10.1209/0295-5075/85/18006

    Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy (Journal article)

    Smith, C. I., Bowfield, A., Cuquerella, M. C., Mansley, C. P., Farrell, T., Harrison, P., . . . Weightman, P. (2009). Detection of DNA hybridisation on a functionalised diamond surface using reflection anisotropy spectroscopy. EPL (Europhysics Letters), 85(1), 18006. doi:10.1209/0295-5075/85/18006

    DOI: 10.1209/0295-5075/85/18006

    Facile synthesis of stable, water-soluble magnetic CoPt hollow nanostructures assisted by multi-thiol ligands (Journal article)

    Lu, L. T., Tung, L. D., Long, J., Fernig, D. G., & Thanh, N. T. K. (2009). Facile synthesis of stable, water-soluble magnetic CoPt hollow nanostructures assisted by multi-thiol ligands. Journal of Materials Chemistry, 19(33), 6023. doi:10.1039/b906839b

    DOI: 10.1039/b906839b

    Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra (Journal article)

    Rudd, T. R., Skidmore, M. A., Guimond, S. E., Cosentino, C., Torri, G., Fernig, D. G., . . . Yates, E. A. (2009). Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra. GLYCOBIOLOGY, 19(1), 52-67. doi:10.1093/glycob/cwn103

    DOI: 10.1093/glycob/cwn103

    2008

    Cobalt nanoparticles as a novel magnetic resonance contrast agent-relaxivities at 1.5 and 3 Tesla (Journal article)

    Parkes, L. M., Hodgson, R., Lu, L. T., Tung, L. D., Robinson, I., Fernig, D. G., & Thanh, N. T. K. (2008). Cobalt nanoparticles as a novel magnetic resonance contrast agent-relaxivities at 1.5 and 3 Tesla. CONTRAST MEDIA & MOLECULAR IMAGING, 3(4), 150-156. doi:10.1002/cmmi.241

    DOI: 10.1002/cmmi.241

    The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis (Journal article)

    Ismail, T. M., Fernig, D. G., Rudland, P. S., Terry, C. J., Wang, G., & Barraclough, R. (2008). The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. CARCINOGENESIS, 29(12), 2259-2266. doi:10.1093/carcin/bgn217

    DOI: 10.1093/carcin/bgn217

    RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin (Journal article)

    Kurisetty, V. V., Johnston, P. G., Johnston, N., Erwin, P., Crowe, P., Fernig, D. G., . . . El-Tanani, M. K. (2008). RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin. ONCOGENE, 27(57), 7139-7149. doi:10.1038/onc.2008.325

    DOI: 10.1038/onc.2008.325

    Robust Ligand Shells for Biological Applications of Gold Nanoparticles (Journal article)

    Duchesne, L., Gentili, D., Comes-Franchini, M., & Fernig, D. G. (2008). Robust Ligand Shells for Biological Applications of Gold Nanoparticles. LANGMUIR, 24(23), 13572-13580. doi:10.1021/la802876u

    DOI: 10.1021/la802876u

    In Situ Stm Studies Of Immobilized Biomolecules At The Electrodeelectrolyte Interface (Chapter)

    Nichols, R. J., Haiss, W., Fernig, D. G., Zalinge, H. V., Schiffrin, D. J., & Ulstrup, J. (n.d.). In Situ Stm Studies Of Immobilized Biomolecules At The Electrodeelectrolyte Interface. In Bioinorganic Electrochemistry (pp. 207-247). Springer Netherlands. doi:10.1007/978-1-4020-6500-2_7

    DOI: 10.1007/978-1-4020-6500-2_7

    Ordered structures of DNA on Au(110) (Journal article)

    Mansley, C. P., Smith, C. I., Cuquerella, M. C., Farrell, T., Fernig, D. G., Edwards, C., & Weightman, P. (2008). Ordered structures of DNA on Au(110). PHYSICA STATUS SOLIDI C - CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 5, NO 8, 2582-+. doi:10.1002/pssc.200779110

    DOI: 10.1002/pssc.200779110

    Reflection anisotropy spectroscopy of decanethiol adsorbed at Au(110)/liquid interfaces (Journal article)

    Bowfield, A., Smith, C. I., Cuquerella, M. C., Farrell, T., Fernig, D. G., Edwards, C., & Weightman, P. (2008). Reflection anisotropy spectroscopy of decanethiol adsorbed at Au(110)/liquid interfaces. PHYSICA STATUS SOLIDI C - CURRENT TOPICS IN SOLID STATE PHYSICS, VOL 5, NO 8, 2600-+. doi:10.1002/pssc.200779111

    DOI: 10.1002/pssc.200779111

    The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis (Journal article)

    Ismail, T. M., Fernig, D. G., Rudland, P. S., Terry, C. J., Wang, G., & Barraclough, R. (2008). The basic C-terminal amino acids of calcium-binding protein S100A4 promote metastasis. Carcinogenesis, 29(12), 2259-2266. doi:10.1093/carcin/bgn217

    DOI: 10.1093/carcin/bgn217

    Supramolecular domains in mixed peptide self-assembled monolayers on gold nanoparticles (Journal article)

    Duchesne, L., Wells, G., Fernig, D. G., Harris, S. A., & Levy, R. (2008). Supramolecular domains in mixed peptide self-assembled monolayers on gold nanoparticles. CHEMBIOCHEM, 9(13), 2127-2134. doi:10.1002/cbic.200800326

    DOI: 10.1002/cbic.200800326

    Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques (Journal article)

    Rudd, T. R., Skidmore, M. A., Guimond, S. E., Guerrini, M., Cosentino, C., Edge, R., . . . Yates, E. A. (2008). Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques. CARBOHYDRATE RESEARCH, 343(12), 2184-2193. doi:10.1016/j.carres.2007.12.019

    DOI: 10.1016/j.carres.2007.12.019

    Size and shape control for water-soluble magnetic cobalt nanoparticles using polymer ligands (Journal article)

    Lu, L. T., Tung, L. D., Robinson, I., Ung, D., Tan, B., Long, J., . . . Thanh, N. T. K. (2008). Size and shape control for water-soluble magnetic cobalt nanoparticles using polymer ligands. JOURNAL OF MATERIALS CHEMISTRY, 18(21), 2453-2458. doi:10.1039/b801800f

    DOI: 10.1039/b801800f

    Neuropilins: a versatile partner of extracellular molecules that regulate development and disease (Journal article)

    Uniewicz, K. A., & Fernig, D. G. (2008). Neuropilins: a versatile partner of extracellular molecules that regulate development and disease. FRONTIERS IN BIOSCIENCE-LANDMARK, 13, 4339-4360. doi:10.2741/3008

    DOI: 10.2741/3008

    The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation (Journal article)

    Skidmore, M. A., Guimond, S. E., Rudd, T. R., Fernig, D. G., Turnbull, J. E., & Yates, E. A. (2008). The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation. CONNECTIVE TISSUE RESEARCH, 49(3-4), 140-144. doi:10.1080/03008200802148595

    DOI: 10.1080/03008200802148595

    The heparanome and regulation of cell function: structures, functions and challenges (Journal article)

    Ori, A., Wilkinson, M. C., & Fernig, D. G. (2008). The heparanome and regulation of cell function: structures, functions and challenges. FRONTIERS IN BIOSCIENCE-LANDMARK, 13, 4309-4338. doi:10.2741/3007

    DOI: 10.2741/3007

    Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density (Journal article)

    Catlow, K. R., Deakin, J. A., Wei, Z., Delehedde, M., Fernig, D. G., Gherardi, E., . . . Lyon, M. (2008). Interactions of hepatocyte growth factor/scatter factor with various glycosaminoglycans reveal an important interplay between the presence of iduronate and sulfate density. JOURNAL OF BIOLOGICAL CHEMISTRY, 283(9), 5235-5248. doi:10.1074/jbc.M706589200

    DOI: 10.1074/jbc.M706589200

    Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain (Journal article)

    Hamma-Kourbali, Y., Bernard-Pierrot, I., Heroult, M., Dalle, S., Caruelle, D., Milhiet, P. E., . . . Courty, J. (2008). Inhibition of the mitogenic, angiogenic and tumorigenic activities of pleiotrophin by a synthetic peptide corresponding to its C-thrombospondin repeat-I domain. JOURNAL OF CELLULAR PHYSIOLOGY, 214(1), 250-259. doi:10.1002/jcp.21191

    DOI: 10.1002/jcp.21191

    2007

    One-step synthesis of monodisperse water-soluble 'dual-responsive' magnetic nanoparticles (Journal article)

    Robinson, I., Alexander, C., Lu, L. T., Tung, L. D., Fernig, D. G., & Thanh, N. T. K. (2007). One-step synthesis of monodisperse water-soluble 'dual-responsive' magnetic nanoparticles. CHEMICAL COMMUNICATIONS, (44), 4602-4604. doi:10.1039/b713528a

    DOI: 10.1039/b713528a

    A basic peptide derived from the HARP C-terminus inhibits anchorage-independent growth of DU145 prostate cancer cells (Journal article)

    Bermek, O., Diamantopoulou, Z., Polykratis, A., Dos Santos, C., Hamma-Kourbali, Y., Burlina, F., . . . Courty, J. (2007). A basic peptide derived from the HARP C-terminus inhibits anchorage-independent growth of DU145 prostate cancer cells. EXPERIMENTAL CELL RESEARCH, 313(19), 4041-4050. doi:10.1016/j.yexcr.2007.07.032

    DOI: 10.1016/j.yexcr.2007.07.032

    Real-time monitoring of the development and stability of biofilms of Streptococcus mutans using the quartz crystal microbalance with dissipation monitoring (Journal article)

    Schofield, A. L., Rudd, T. R., Martin, D. S., Fernig, D. G., & Edwards, C. (2007). Real-time monitoring of the development and stability of biofilms of Streptococcus mutans using the quartz crystal microbalance with dissipation monitoring. BIOSENSORS & BIOELECTRONICS, 23(3), 407-413. doi:10.1016/j.bios.2007.05.001

    DOI: 10.1016/j.bios.2007.05.001

    Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives (Journal article)

    Rudd, T. R., Guimond, S. E., Skidmore, M. A., Duchesne, L., Guerrini, M., Torri, G., . . . Yates, E. A. (2007). Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives. GLYCOBIOLOGY, 17(9), 983-993. doi:10.1093/glycob/cwm062

    DOI: 10.1093/glycob/cwm062

    Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives. (Journal article)

    Rudd, T. R., Guimond, S. E., Skidmore, M. A., Duchesne, L., Guerrini, M., Torri, G., . . . Yates, E. A. (2007). Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives.. Glycobiology, 17(9), 983-993. doi:10.1093/glycob/cwm062

    DOI: 10.1093/glycob/cwm062

    The Heparin/Heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue (Journal article)

    Vanpouille, C., Deligny, A., Delehedde, M., Denys, A., Melchior, A., Lienard, X., . . . Allain, F. (2007). The Heparin/Heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. JOURNAL OF BIOLOGICAL CHEMISTRY, 282(33), 24416-24429. doi:10.1074/jbc.M701835200

    DOI: 10.1074/jbc.M701835200

    Determination of size and concentration of gold nanoparticles from UV-Vis spectra (Journal article)

    Haiss, W., Thanh, N. T. K., Aveyard, J., & Fernig, D. G. (2007). Determination of size and concentration of gold nanoparticles from UV-Vis spectra. ANALYTICAL CHEMISTRY, 79(11), 4215-4221. doi:10.1021/ac0702084

    DOI: 10.1021/ac0702084

    Novel 'phage display antibodies identify distinct heparan sulfate domains in developing mammalian lung (Journal article)

    Thompson, S. M., Connell, M. G., Fernig, D. G., Ten Dam, G. B., van Kuppevelt, T. H., Turnbull, J. E., . . . Losty, P. D. (2007). Novel 'phage display antibodies identify distinct heparan sulfate domains in developing mammalian lung. PEDIATRIC SURGERY INTERNATIONAL, 23(5), 411-417. doi:10.1007/s00383-006-1864-8

    DOI: 10.1007/s00383-006-1864-8

    Silver and gold nanoparticle-coated membranes for femtomole detection of small proteins and peptides by Dot and Western blot (Journal article)

    Duchesne, L., & Fernig, D. G. (2007). Silver and gold nanoparticle-coated membranes for femtomole detection of small proteins and peptides by Dot and Western blot. ANALYTICAL BIOCHEMISTRY, 362(2), 287-289. doi:10.1016/j.ab.2006.12.022

    DOI: 10.1016/j.ab.2006.12.022

    Adsorption of calf thymus DNA on Au(110) studied by reflection anisotropy spectroscopy (Journal article)

    Cuquerella, M. C., Smith, C. I., Fernig, D. G., Edwards, C., & Weightman, P. (2007). Adsorption of calf thymus DNA on Au(110) studied by reflection anisotropy spectroscopy. LANGMUIR, 23(4), 2078-2082. doi:10.1021/la062839j

    DOI: 10.1021/la062839j

    One-step synthesis of monodisperse water-soluble ‘dual-responsive’ magnetic nanoparticles (Journal article)

    Robinson, I., Alexander, C., Lu, L. T., Tung, L. D., Fernig, D. G., & Thanh, N. T. K. (2007). One-step synthesis of monodisperse water-soluble ‘dual-responsive’ magnetic nanoparticles. Chemical Communications. doi:10.1039/b713528a

    DOI: 10.1039/b713528a

    Site-specific interactions of copper (II) ions with heparin revealed with complementary (Journal article)

    Rudd, T. R., Skidmore, M. A., Guimond, S. E., Guerrini, M., Cosentino, C., Edge, R., . . . Yates, E. A. (2007). Site-specific interactions of copper (II) ions with heparin revealed with complementary. Carbohydrate Research. Retrieved from doi:10.1016/j.carres.2007.12.0

    Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques (Journal article)

    Rudd, T. R., Skidmore, M. A., Guimond, S. E., Guerrini, M., Cosentino, C., Edge, R., . . . Yates, E. A. (2007). Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques. Carbohydr Res. Retrieved from http://www.ncbi.nlm.nih.gov/

    2006

    Characterisation of membrane mimetics on a dual polarisation interferometer (Journal article)

    Terry, C. J., Popplewell, J. F., Swann, M. J., Freeman, N. J., & Fernig, D. G. (2006). Characterisation of membrane mimetics on a dual polarisation interferometer. BIOSENSORS & BIOELECTRONICS, 22(5), 627-632. doi:10.1016/j.bios.2006.01.021

    DOI: 10.1016/j.bios.2006.01.021

    Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis (Journal article)

    Featherstone, N. C., Connell, M. G., Fernig, D. G., Wray, S., Burdyga, T. V., Losty, P. D., & Jesudason, E. C. (2006). Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 35(5), 571-578. doi:10.1165/rcmb.2006-0079OC

    DOI: 10.1165/rcmb.2006-0079OC

    Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis. (Journal article)

    Featherstone, N. C., Connell, M. G., Fernig, D. G., Wray, S., Burdyga, T. V., Losty, P. D., & Jesudason, E. C. (2006). Airway smooth muscle dysfunction precedes teratogenic congenital diaphragmatic hernia and may contribute to hypoplastic lung morphogenesis.. American journal of respiratory cell and molecular biology, 35(5), 571-578. doi:10.1165/rcmb.2006-0079oc

    DOI: 10.1165/rcmb.2006-0079oc

    Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth (Journal article)

    Jesudason, E. C., Smith, N. P., Connell, M. G., Spiller, D. G., White, M. R. H., Fernig, D. G., & Losty, P. D. (2006). Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 291(4), L559-L565. doi:10.1152/ajplung.00498.2005

    DOI: 10.1152/ajplung.00498.2005

    N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding (Journal article)

    Duchesne, L., Tissot, B., Rudd, T. R., Dell, A., & Fernig, D. G. (2006). N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(37), 27178-27189. doi:10.1074/jbc.M601248200

    DOI: 10.1074/jbc.M601248200

    Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes (Conference Paper)

    Yates, E. A., Terry, C. J., Rees, C., Rudd, T. R., Duchesne, L., Skidmore, M. A., . . . Fernig, D. G. (2006). Protein-GAG interactions: new surface-based techniques, spectroscopies and nanotechnology probes. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 34 (pp. 427-430). doi:10.1042/BST0340427

    DOI: 10.1042/BST0340427

    A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography (Journal article)

    Levy, R., Wang, Z. X., Duchesne, L., Doty, R. C., Cooper, A. I., Brust, M., & Fernig, D. G. (2006). A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography. CHEMBIOCHEM, 7(4), 592-594. doi:10.1002/cbic.200500457

    DOI: 10.1002/cbic.200500457

    Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface (Journal article)

    LeParc, R., Smith, C. I., Cuquerella, M. C., Williams, R. L., Fernig, D. G., Edwards, C., . . . Weightman, P. (2006). Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface. LANGMUIR, 22(7), 3413-3420. doi:10.1021/la052584u

    DOI: 10.1021/la052584u

    Orientation of ordered structures of cytosine and cytidine 5 '-monophosphate adsorbed at Au(110)/liquid interfaces (Journal article)

    Weightman, P., Dolan, G. J., Smith, C. I., Cuquerella, M. C., Almond, N. J., Farrell, T., . . . Martin, D. S. (2006). Orientation of ordered structures of cytosine and cytidine 5 '-monophosphate adsorbed at Au(110)/liquid interfaces. PHYSICAL REVIEW LETTERS, 96(8). doi:10.1103/PhysRevLett.96.086102

    DOI: 10.1103/PhysRevLett.96.086102

    Kinase-catalyzed modification of gold nanoparticles: A new approach to colorimetric kinase activity screening (Journal article)

    Wang, Z. X., Levy, R., Fernig, D. G., & Brust, M. (2006). Kinase-catalyzed modification of gold nanoparticles: A new approach to colorimetric kinase activity screening. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128(7), 2214-2215. doi:10.1021/ja058135y

    DOI: 10.1021/ja058135y

    'Orientation of Ordered Structures of Cytosine and Cytidine 5'-Monophosphate Adsorbed at Au(110)/Electrolyte Interfaces' (Journal article)

    Weightman, P., Dolan, G. J., Smith, C. I., Cuquerella, M. C., Almond, N. J., Farrell, T., . . . Martin, D. S. (2006). 'Orientation of Ordered Structures of Cytosine and Cytidine 5'-Monophosphate Adsorbed at Au(110)/Electrolyte Interfaces'. Physical Review Letters, 96(8), 086102.

    Orientation of Ordered Structures of Cytosine and Cytidine5'-Monophosphate Adsorbed at Au(110)/Liquid Interfaces (Journal article)

    Weightman, P., Dolan, G. J., Smith, C. I., Cuquerella, M. C., Almond, N. J., Farrell, T., . . . Martin, D. S. (n.d.). Orientation of Ordered Structures of Cytosine and Cytidine5'-Monophosphate Adsorbed at Au(110)/Liquid Interfaces. Physical Review Letters, 96(8). doi:10.1103/physrevlett.96.086102

    DOI: 10.1103/physrevlett.96.086102

    Orientation of ordered structures of cytosine and cytidine 5 '-monophosphate adsorbed at Au(110)/liquid interfaces (Journal article)

    Weightman, P., Dolan, G. J., Smith, C. I., Cuquerella, M. C., Almond, N. J., Farrell, T., . . . Martin, D. S. (2006). Orientation of ordered structures of cytosine and cytidine 5 '-monophosphate adsorbed at Au(110)/liquid interfaces. Physical Review Letters, 96(8).

    Protein-GAG interactions: news surface-based techniques spectroscopies and nanotechnology probes (Journal article)

    Yates, E. A., Terry, C. J., Rees, C., Rudd, T. R., Duchense, L., Skidmore, M. A., . . . Fernig, D. G. (2006). Protein-GAG interactions: news surface-based techniques spectroscopies and nanotechnology probes. Unknown Journal, 34(34), 427-430.

    2005

    Protein-like Ag nanoparticles for biological sensing applications (Conference Paper)

    Doty, R. C., & Fernig, D. G. (2005). Protein-like Ag nanoparticles for biological sensing applications. In AIChE Annual Meeting, Conference Proceedings (pp. 14087).

    Using the peptide toolbox to create protein-like nanoparticles for applications in bionanotechnology (Conference Paper)

    Doty, R. C., Fernig, D. G., & Levy, R. (2005). Using the peptide toolbox to create protein-like nanoparticles for applications in bionanotechnology. In AIChE Annual Meeting, Conference Proceedings (pp. 14125).

    Nanoparticle conjugates and method of production thereof (Patent)

    Fernig, D. G., & Smith, J. A. (2005). Nanoparticle conjugates and method of production thereof.

    Extremely stable water-soluble Ag nanoparticles (Journal article)

    Doty, R. C., Tshikhudo, T. R., Brust, M., & Fernig, D. G. (2005). Extremely stable water-soluble Ag nanoparticles. CHEMISTRY OF MATERIALS, 17(18), 4630-4635. doi:10.1021/cm0508017

    DOI: 10.1021/cm0508017

    Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung (Journal article)

    Featherstone, N. C., Jesudason, E. C., Connell, M. G., Fernig, D. G., Wray, S., Losty, P. D., & Burdyga, T. V. (2005). Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 33(2), 153-160. doi:10.1165/rcmb.2005-0137OC

    DOI: 10.1165/rcmb.2005-0137OC

    The C-terminal region of S100A4 is important for its metastasis-inducing properties (Journal article)

    Zhang, S., Wang, G. Z., Liu, D., Bao, Z. Z., Fernig, D. G., Rudland, P. S., & Barraclough, R. (2005). The C-terminal region of S100A4 is important for its metastasis-inducing properties. ONCOGENE, 24(27), 4401-4411. doi:10.1038/sj.onc.1208663

    DOI: 10.1038/sj.onc.1208663

    The peptide route to multifunctional gold nanoparticles. (Journal article)

    Wang, Z., Lévy, R., Fernig, D. G., & Brust, M. (2005). The peptide route to multifunctional gold nanoparticles.. Bioconjugate chemistry, 16(3), 497-500. doi:10.1021/bc050047f

    DOI: 10.1021/bc050047f

    Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2 (Journal article)

    West, D. C., Rees, C. G., Duchesne, L., Patey, S. J., Terry, C. J., Turnbull, J. E., . . . Fernig, D. G. (2005). Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(14), 13457-13464. doi:10.1074/jbc.M410924200

    DOI: 10.1074/jbc.M410924200

    Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes (Journal article)

    Wang, G. Z., Zhang, S., Fernig, D. G., Martin-Fernandez, M., Rudland, P. S., & Barraclough, R. (2005). Mutually antagonistic actions of S100A4 and S100A1 on normal and metastatic phenotypes. ONCOGENE, 24(8), 1445-1454. doi:10.1038/sj.onc.1208291

    DOI: 10.1038/sj.onc.1208291

    Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis (Journal article)

    Jesudason, E. C., Smith, N. P., Connell, M. G., Spiller, D. G., White, M. R. H., Fernig, D. G., & Losty, P. D. (2005). Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 32(2), 118-127. doi:10.1165/rcmb.2004-0304OC

    DOI: 10.1165/rcmb.2004-0304OC

    Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy (Journal article)

    Zhang, S., Wang, G. Z., Fernig, D. G., Rudland, P. S., Webb, S. E. D., Barraclough, R., & Martin-Fernandez, M. (2005). Interaction of metastasis-inducing S100A4 protein in vivo by fluorescence lifetime imaging microscopy. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 34(1), 19-27. doi:10.1007/s00249-004-0428-x

    DOI: 10.1007/s00249-004-0428-x

    Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis (Journal article)

    Jesudason, E. C., Smith, N. P., Connell, M. G., Spiller, D. G., White, M. R. H., Fernig, D. G., & Losty, P. D. (2005). Developing rat lung has a sided pacemaker region for morphogenesis-related airway peristalsis. American Journal of Respiratory Cell and Molecular Biology, 32(2), 118-127. doi:10.1165/rcmb.2004-0304OC

    DOI: 10.1165/rcmb.2004-0304OC

    Peptides as capping ligands for in situ synthesis of water soluble Co nanoparticles for bioapplications (Journal article)

    Thanh, N. T. K., Puntes, V. F., Tung, L. D., & Fernig, D. G. (2005). Peptides as capping ligands for in situ synthesis of water soluble Co nanoparticles for bioapplications. Fifth International Conference on Fine Particle Magnetism, 17, 70-76. doi:10.1088/1742-6596/17/1/012

    DOI: 10.1088/1742-6596/17/1/012

    The C-terminal region of S100A4 is important for its metastasis-inducing properties (Journal article)

    Zhang, S., Wang, G., Liu, D., Bao, Z., Fernig, D. G., Rudland, P. S., & Barraclough, R. (2005). The C-terminal region of S100A4 is important for its metastasis-inducing properties. Oncogene, 24(27), 4401-4411.

    The peptide route to multifunctional gold nanoparticles (Journal article)

    Wang, Z., Levy, R., Fernig, D. G., & Brust, M. (2005). The peptide route to multifunctional gold nanoparticles. BIOCONJUGATE CHEMISTRY, 16(3), 497-500. doi:10.1021/bc050047f

    DOI: 10.1021/bc050047f

    2004

    Attachment of glycosaminoglycan oligosaccharides to thiol-derivatised gold surfaces (Journal article)

    Skidmore, M. A., Patey, S. J., Thanh, N. T. K., Fernig, D. G., Turnbull, J. E., & Yates, E. A. (2004). Attachment of glycosaminoglycan oligosaccharides to thiol-derivatised gold surfaces. CHEMICAL COMMUNICATIONS, (23), 2700-2701. doi:10.1039/b411726c

    DOI: 10.1039/b411726c

    The adsorption of bipyridine molecules on Au(110) as measured by reflection anisotropy spectroscopy (Journal article)

    Smith, C. I., Dolan, G. J., Farrell, T., Maunder, A. J., Fernig, D. G., Edwards, C., & Weightman, P. (2004). The adsorption of bipyridine molecules on Au(110) as measured by reflection anisotropy spectroscopy. JOURNAL OF PHYSICS-CONDENSED MATTER, 16(39), S4385-S4392. doi:10.1088/0953-8984/16/39/013

    DOI: 10.1088/0953-8984/16/39/013

    Rational and combinatorial design of peptide capping Ligands for gold nanoparticles (Journal article)

    Levy, R., Thanh, N. T. K., Doty, R. C., Hussain, I., Nichols, R. J., Schiffrin, D. J., . . . Fernig, D. G. (2004). Rational and combinatorial design of peptide capping Ligands for gold nanoparticles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126(32), 10076-10084. doi:10.1021/ja0487269

    DOI: 10.1021/ja0487269

    Heterodimeric interaction and interfaces of S100A1 and S100P (Journal article)

    Wang, G. Z., Zhang, S., Fernig, D. G., Spiller, D., Martin-Fernandez, M., Zhang, H. M., . . . Barraclough, R. (2004). Heterodimeric interaction and interfaces of S100A1 and S100P. BIOCHEMICAL JOURNAL, 382, 375-383. doi:10.1042/BJ20040142

    DOI: 10.1042/BJ20040142

    The analysis of the fibroblast growth factor ligand-receptor complex using a quartz crystal microbalance-dissipation (Journal article)

    Rudd, T., Duchesne, L., Fernig, D. G., & Nichols, R. J. (2004). The analysis of the fibroblast growth factor ligand-receptor complex using a quartz crystal microbalance-dissipation. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 85(4), A72-A73. doi:10.1111/j.0959-9673.2004.390al.x

    DOI: 10.1111/j.0959-9673.2004.390al.x

    Interactions of heparin/heparan sulfate with proteins: Appraisal of structural factors and epxerimental approaches (Journal article)

    Powell, A. K., Yates, E. A., Fernig, D. G., & Turnbull, J. E. (2004). Interactions of heparin/heparan sulfate with proteins: Appraisal of structural factors and epxerimental approaches. GLYCOBIOLOGY, 14(4), 17R-30R. doi:10.1093/glycob/cwh051

    DOI: 10.1093/glycob/cwh051

    Mitogen-activated protein kinase (MAPK) signalling links airway peristalsis and lung growth in an experimental model of congenital diaphragmatic hernia (Journal article)

    Smith, N. P., Jesudason, E. C., Connell, M. G., Fernig, D. G., & Losty, P. D. (2004). Mitogen-activated protein kinase (MAPK) signalling links airway peristalsis and lung growth in an experimental model of congenital diaphragmatic hernia. British Journal of Surgery, 91(9), 1225.

    Molecular recognition and modulation of hepatocyte growth factor activity by heparan and dermatan sulfates (Journal article)

    Catlow, K., Deakin, J. A., Delehedde, M., Fernig, D. G., Pavao, M. S. G., Gallagher, J. T., & Lyon, M. (2004). Molecular recognition and modulation of hepatocyte growth factor activity by heparan and dermatan sulfates. International Journal of Experimental Pathology, 85(4), A58.

    Nanoscale science: a big step towards the Holy Grail of single molecule biochemistry and molecular biology (Journal article)

    Doty, R. C., Fernig, D. G., & Levy, R. (2004). Nanoscale science: a big step towards the Holy Grail of single molecule biochemistry and molecular biology. CELLULAR AND MOLECULAR LIFE SCIENCES, 61(15), 1843-1849. doi:10.1007/s00018-004-4036-9

    DOI: 10.1007/s00018-004-4036-9

    Nanoscale science: a big step towards the Holy Grail of single molecule biochemistry and molecular biology (Journal article)

    Doty, R. C., Fernig, D. G., & Levy, R. (2004). Nanoscale science: a big step towards the Holy Grail of single molecule biochemistry and molecular biology. Unknown Journal, 61, 1841-1849.

    2003

    Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka) (vol 286, pg 1212, 2001) (Journal article)

    Chen, H. L., Fernig, D. G., Rudland, P. S., Sparks, A., Wilkinson, M. C., & Barraclough, R. (2003). Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka) (vol 286, pg 1212, 2001). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 308(2), 408. doi:10.1016/S0006-291X(03)01310-X

    DOI: 10.1016/S0006-291X(03)01310-X

    A gravimetric analysis of protein-oligosaccharide interactions (Journal article)

    Rudd, T., Gallagher, J. T., Ron, D., Nichols, R. J., & Fernig, D. G. (2003). A gravimetric analysis of protein-oligosaccharide interactions. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 349-351. doi:10.1042/BST0310349

    DOI: 10.1042/BST0310349

    Hepatocyte growth factor/scatter factor and its interaction with heparan sulphate and dermatan sulphate (Journal article)

    Catlow, K., Deakin, J. A., Delehedde, M., Fernig, D. G., Gallagher, J. T., Pavao, M. S. G., & Lyon, M. (2003). Hepatocyte growth factor/scatter factor and its interaction with heparan sulphate and dermatan sulphate. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 352-353. doi:10.1042/BST0310352

    DOI: 10.1042/BST0310352

    The crystal structure at 2 angstrom resolution of the Ca2+-binding protein S100P (Journal article)

    Zhang, H. M., Wang, G. Z., Ding, Y., Wang, Z. L., Barraclough, R., Rudland, P. S., . . . Rao, Z. H. (2003). The crystal structure at 2 angstrom resolution of the Ca2+-binding protein S100P. JOURNAL OF MOLECULAR BIOLOGY, 325(4), 785-794. doi:10.1016/S0022-2836(02)01278-0

    DOI: 10.1016/S0022-2836(02)01278-0

    The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray (Journal article)

    Zhang, H., Wang, G., Ding, Y., Wang, Z., Barraclough, R., Rudland, P. S., . . . Rao, Z. (n.d.). The Crystal Structure of Ca+-bound Human S100P Determined at 2.0A Resolution by X-ray. doi:10.2210/pdb1j55/pdb

    DOI: 10.2210/pdb1j55/pdb

    A gravimetric analysis of protein-oligosaccharide interactions (Journal article)

    Rudd, T., Gallagher, J. T., Ron, D., Nichols, R. J., & Fernig, D. G. (2003). A gravimetric analysis of protein-oligosaccharide interactions. Biochemical Society Transactions, 31, 349-351.

    Hypoplastic lung primordia have reduced frequency of peristaltic airway contractions in a model of congenital diaphragmatic hernia (Journal article)

    Smith, N. P., Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2003). Hypoplastic lung primordia have reduced frequency of peristaltic airway contractions in a model of congenital diaphragmatic hernia. British Journal of Surgery, 90(5), 614.

    2002

    Proteoglycans in Inflammation (Journal article)

    Delehedde, M., Allain, F., Payne, S. J., Borgo, R., Vanpouille, C., Fernig, D. G., & Deudon, E. (2002). Proteoglycans in Inflammation. Current Medicinal Chemistry -Anti- Inflammatory & Anti-Allergy Agents, 1(2), 89-102. doi:10.2174/1568014023355935

    DOI: 10.2174/1568014023355935

    Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts (Journal article)

    Delehedde, M., Lyon, M., Gallagher, J. T., Rudland, P. S., & Fernig, D. G. (2002). Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts. BIOCHEMICAL JOURNAL, 366, 235-244. doi:10.1042/bj20011718

    DOI: 10.1042/bj20011718

    Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate - Implications for dynamic assembly of a ternary signaling complex (Journal article)

    Powell, A. K., Fernig, D. G., & Turnbull, J. E. (2002). Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate - Implications for dynamic assembly of a ternary signaling complex. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(32), 28554-28563. doi:10.1074/jbc.M111754200

    DOI: 10.1074/jbc.M111754200

    Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes (Journal article)

    Delehedde, M., Lyon, M., Vidyasagar, R., McDonnell, T. J., & Fernig, D. G. (2002). Hepatocyte growth factor/scatter factor binds to small heparin-derived oligosaccharides and stimulates the proliferation of human HaCaT keratinocytes. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(14), 12456-12462. doi:10.1074/jbc.M111345200

    DOI: 10.1074/jbc.M111345200

    Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes (Journal article)

    Ostrovsky, O., Berman, B., Gallagher, J., Mulloy, B., Fernig, D. G., Delehedde, M., & Ron, D. (2002). Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(4), 2444-2453. doi:10.1074/jbc.M108540200

    DOI: 10.1074/jbc.M108540200

    2001

    Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity (Journal article)

    Bechard, D., Gentina, T., Delehedde, M., Scherpereel, A., Lyon, M., Aumercier, M., . . . Lassalle, P. (2001). Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(51), 48341-48349. doi:10.1074/jbc.M108395200

    DOI: 10.1074/jbc.M108395200

    Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors (Journal article)

    El-Tanani, M., Fernig, D. G., Barraclough, R., Green, C., & Rudland, P. (2001). Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(45), 41675-41682. doi:10.1074/jbc.M103966200

    DOI: 10.1074/jbc.M103966200

    Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka) (Journal article)

    Chen, H. L., Fernig, D. G., Rudland, P. S., Sparks, A., Wilkinson, M. C., & Barraclough, R. (2001). Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 286(5), 1212-1217. doi:10.1006/bbrc.2001.5517

    DOI: 10.1006/bbrc.2001.5517

    Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways (Journal article)

    Delehedde, M., Sergeant, N., Lyon, M., Rudland, P. S., & Fernig, D. G. (2001). Hepatocyte growth factor/scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways. EUROPEAN JOURNAL OF BIOCHEMISTRY, 268(16), 4423-4429. doi:10.1046/j.1432-1327.2001.02363.x

    DOI: 10.1046/j.1432-1327.2001.02363.x

    Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44 (Journal article)

    Singh, R., Campbell, B. J., Yu, L. G., Fernig, D. G., Milton, J. D., Goodlad, R., . . . Rhodes, J. M. (2001). Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44. GLYCOBIOLOGY, 11(7), 587-592. doi:10.1093/glycob/11.7.587

    DOI: 10.1093/glycob/11.7.587

    Proteoglycans: Pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland (Journal article)

    Delehedde, M., Lyon, M., Sergeant, N., Rahmoune, H., & Fernig, D. G. (2001). Proteoglycans: Pericellular and cell surface multireceptors that integrate external stimuli in the mammary gland. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 6(3), 253-273. doi:10.1023/A:1011367423085

    DOI: 10.1023/A:1011367423085

    Use of a biosensor to determine the binding kinetics of five lectins for Galactosyl-N-acetylgalactosamine (Journal article)

    Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Use of a biosensor to determine the binding kinetics of five lectins for Galactosyl-N-acetylgalactosamine. GLYCOCONJUGATE JOURNAL, 18(7), 565-569. doi:10.1023/A:1019655303395

    DOI: 10.1023/A:1019655303395

    Does the developing liver inhibit early lung growth in congenital diaphragmatic hernia? (Journal article)

    Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2001). Does the developing liver inhibit early lung growth in congenital diaphragmatic hernia?. PEDIATRIC SURGERY INTERNATIONAL, 17(4), 288-293. doi:10.1007/s003830100596

    DOI: 10.1007/s003830100596

    Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins (Journal article)

    Yu, L. G., Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins. JOURNAL OF CELLULAR PHYSIOLOGY, 186(2), 282-287. doi:3.0.CO;2-2">10.1002/1097-4652(200102)186:2<282::AID-JCP1028>3.0.CO;2-2

    DOI: 10.1002/1097-4652(200102)186:2<282::AID-JCP1028>3.0.CO;2-2

    Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins. (Journal article)

    Yu, L. G., Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins.. Journal of cellular physiology, 186(2), 282-287. doi:10.1002/1097-4652(200102)186:2<282::aid-jcp1028>3.0.co;2-2

    DOI: 10.1002/1097-4652(200102)186:2<282::aid-jcp1028>3.0.co;2-2

    Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44 (Journal article)

    Singh, R., Campbell, B. J., Yu, L. G., Fernig, D. G., Milton, J. D., Goodlad, R. A., . . . Rhodes, J. M. (2001). Cell surface-expressed Thomsen-Friedenreich antigen in colon cancer is predominantly carried on high molecular weight splice variants of CD44. Glycobiology, 11(7), 587-9052. doi:10.1093/glycob/11.7.587

    DOI: 10.1093/glycob/11.7.587

    Jackfruit lectin (jacalin), a Thomsen-Friedenreich antigen-binding lectin, inhibits proliferation of HT29 human colon cancer cells by altering cell surface tyrosine phosphorylation and down regulating MAP kinase kinase (MEK1/2) and MAP kinase (Erk1/2) (Journal article)

    Yu, L. G., Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Jackfruit lectin (jacalin), a Thomsen-Friedenreich antigen-binding lectin, inhibits proliferation of HT29 human colon cancer cells by altering cell surface tyrosine phosphorylation and down regulating MAP kinase kinase (MEK1/2) and MAP kinase (Erk1/2). Gastroenterology, 120(5), A665.

    Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins (Journal article)

    Yu, L. G., Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Opposite effects on human colon cancer cell proliferation of two dietary Thomsen-Friedenreich antigen-binding lectins. J Cell Physiol, 186(2), 282-287. doi:3.0.CO;2-2">10.1002/1097-4652(200102)186:2<282::AID-JCP1028>3.0.CO;2-2

    DOI: 10.1002/1097-4652(200102)186:2<282::AID-JCP1028>3.0.CO;2-2

    Optical biosensor techniques to analyze protein-polysaccharide interactions. (Journal article)

    Fernig, D. G. (2001). Optical biosensor techniques to analyze protein-polysaccharide interactions.. Methods in molecular biology (Clifton, N.J.), 171, 505-518. doi:10.1385/1-59259-209-0:505

    DOI: 10.1385/1-59259-209-0:505

    Use of a biosensor to determine the binding kinetics of five lectins for Galactosyl-N-acetylgalactosamine (Journal article)

    Milton, J. D., Fernig, D. G., & Rhodes, J. M. (2001). Use of a biosensor to determine the binding kinetics of five lectins for Galactosyl-N-acetylgalactosamine. Glycoconjugate Journal, 18(7), 565-569.

    2000

    Heparan Sulphate - Regulation of growth factors in the mammary gland (Conference Paper)

    Bateman, K. L., Delehedde, M., Sergeant, N., Wartelle, I., Vidyasagar, R., & Fernig, D. G. (2000). Heparan Sulphate - Regulation of growth factors in the mammary gland. In BIOLOGY OF THE MAMMARY GLAND Vol. 480 (pp. 65-69). Retrieved from http://gateway.webofknowledge.com/

    Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex (Journal article)

    Baveye, S., Elass, E., Fernig, D. G., Blanquart, C., Mazurier, J., & Legrand, D. (2000). Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex. INFECTION AND IMMUNITY, 68(12), 6519-6525. doi:10.1128/IAI.68.12.6519-6525.2000

    DOI: 10.1128/IAI.68.12.6519-6525.2000

    Fibroblast growth factor-2 stimulation of p42/44(MAPK) phosphorylation and I kappa B degradation is regulated by heparan sulfate/heparin in rat mammary fibroblasts (Journal article)

    Delehedde, M., Seve, M., Sergeant, N., Wartelle, I., Lyon, M., Rudland, P. S., & Fernig, D. G. (2000). Fibroblast growth factor-2 stimulation of p42/44(MAPK) phosphorylation and I kappa B degradation is regulated by heparan sulfate/heparin in rat mammary fibroblasts. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(43), 33905-33910. doi:10.1074/jbc.M005949200

    DOI: 10.1074/jbc.M005949200

    Stimulation of DNA synthesis and cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained phosphorylation of mitogen-activated protein kinases p42/44 (Journal article)

    Sergeant, N., Lyon, M., Rudland, P. S., Fernig, D. G., & Delehedde, M. (2000). Stimulation of DNA synthesis and cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained phosphorylation of mitogen-activated protein kinases p42/44. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(22), 17094-17099. doi:10.1074/jbc.M000237200

    DOI: 10.1074/jbc.M000237200

    Heparin and in-vitro experimental lung hypoplasia (Journal article)

    Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2000). Heparin and in-vitro experimental lung hypoplasia. PEDIATRIC SURGERY INTERNATIONAL, 16(4), 247-251. doi:10.1007/s003830050738

    DOI: 10.1007/s003830050738

    Intracellular trafficking and release of intact edible mushroom lectin from HT29 human colon cancer cells (Journal article)

    Yu, L. G., Fernig, D. G., & Rhodes, J. M. (2000). Intracellular trafficking and release of intact edible mushroom lectin from HT29 human colon cancer cells. EUROPEAN JOURNAL OF BIOCHEMISTRY, 267(7), 2122-2126. doi:10.1046/j.1432-1327.2000.01230.x

    DOI: 10.1046/j.1432-1327.2000.01230.x

    Peanut lectin-induced proliferation of HT29 human colon cancer cells is mediated by activation of nitrogen-activated protein kinase (MAPK). (Conference Paper)

    Singh, R., Yu, L. G., Fernig, D. G., Delehedde, M., Campbell, B. J., & Rhodes, J. M. (2000). Peanut lectin-induced proliferation of HT29 human colon cancer cells is mediated by activation of nitrogen-activated protein kinase (MAPK).. In GASTROENTEROLOGY Vol. 118 (pp. A614). doi:10.1016/S0016-5085(00)84595-3

    DOI: 10.1016/S0016-5085(00)84595-3

    Differential regulation of FGF-1 and-2 mitogenic activity is related to their kinetics of binding to heparan sulfate in MDA-MB-231 human breast cancer cells (Journal article)

    Fernig, D. G., Chen, H. L., Rahmoune, H., Descamps, S., Boilly, B., & Hondermarck, H. (2000). Differential regulation of FGF-1 and-2 mitogenic activity is related to their kinetics of binding to heparan sulfate in MDA-MB-231 human breast cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 267(3), 770-776. doi:10.1006/bbrc.1999.2028

    DOI: 10.1006/bbrc.1999.2028

    Presentation of IFN-gamma to nitric oxide-producing cells: A novel function for mast cells (Journal article)

    Brooks, B., Briggs, D. M., Eastmond, N. C., Fernig, D. G., & Coleman, J. W. (2000). Presentation of IFN-gamma to nitric oxide-producing cells: A novel function for mast cells. JOURNAL OF IMMUNOLOGY, 164(2), 573-579. doi:10.4049/jimmunol.164.2.573

    DOI: 10.4049/jimmunol.164.2.573

    Cell proliferation and apoptosis in experimental lung hypoplasia (Journal article)

    Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2000). Cell proliferation and apoptosis in experimental lung hypoplasia. JOURNAL OF PEDIATRIC SURGERY, 35(1), 129-133. doi:10.1016/S0022-3468(00)80092-5

    DOI: 10.1016/S0022-3468(00)80092-5

    Cell proliferation and apoptosis in experimental lung hypoplasia (Journal article)

    JESUDASON, E., CONNELL, M., FERNIG, D., LLOYD, D., & LOSTY, P. (2000). Cell proliferation and apoptosis in experimental lung hypoplasia. Journal of Pediatric Surgery, 35(1), 129-133. doi:10.1016/s0022-3468(00)80092-5

    DOI: 10.1016/s0022-3468(00)80092-5

    Early lung malformations in congenital diaphragmatic hernia (Journal article)

    Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2000). Early lung malformations in congenital diaphragmatic hernia. JOURNAL OF PEDIATRIC SURGERY, 35(1), 124-127. doi:10.1016/S0022-3468(00)80028-7

    DOI: 10.1016/S0022-3468(00)80028-7

    Early lung malformations in congenital diaphragmatic hernia (Journal article)

    JESUDASON, E., CONNEL, M., FERNIG, D., LLOYD, D., & LOSTY, P. (2000). Early lung malformations in congenital diaphragmatic hernia. Journal of Pediatric Surgery, 35(1), 124-128. doi:10.1016/s0022-3468(00)80091-3

    DOI: 10.1016/s0022-3468(00)80091-3

    In vitro effects of growth factors on lung hypoplasia in a model of congenital diaphragmatic hernia (Journal article)

    Jesudason, E. C., Connell, M. G., Fernig, D. G., Lloyd, D. A., & Losty, P. D. (2000). In vitro effects of growth factors on lung hypoplasia in a model of congenital diaphragmatic hernia. JOURNAL OF PEDIATRIC SURGERY, 35(6), 914-922. doi:10.1053/jpsu.2000.6919

    DOI: 10.1053/jpsu.2000.6919

    1999

    Modulation of mammary development and programmed cell death by the frequency of milk removal in lactating goats (Journal article)

    Li, P., Rudland, P. S., Fernig, D. G., Finch, L. M. B., & Wilde, C. J. (1999). Modulation of mammary development and programmed cell death by the frequency of milk removal in lactating goats. JOURNAL OF PHYSIOLOGY-LONDON, 519(3), 885-900. doi:10.1111/j.1469-7793.1999.0885n.x

    DOI: 10.1111/j.1469-7793.1999.0885n.x

    Identification of cell types in the developing goat mammary gland (Journal article)

    Li, P., Wilde, C. J., Finch, L. M. B., Fernig, D. G., & Rudland, P. S. (1999). Identification of cell types in the developing goat mammary gland. HISTOCHEMICAL JOURNAL, 31(6), 379-393. doi:10.1023/A:1003700224900

    DOI: 10.1023/A:1003700224900

    Glycosaminoglycans differentially bind HARP and modulate its biological activity (Journal article)

    Vacherot, F., Delbe, J., Heroult, M., Barritault, D., Fernig, D. G., & Courty, J. (1999). Glycosaminoglycans differentially bind HARP and modulate its biological activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(12), 7741-7747. doi:10.1074/jbc.274.12.7741

    DOI: 10.1074/jbc.274.12.7741

    Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import (Journal article)

    Yu, L. G., Fernig, D. G., White, M. R. H., Spiller, D. G., Appleton, P., Evans, R. C., . . . Rhodes, J. M. (1999). Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(8), 4890-4899. doi:10.1074/jbc.274.8.4890

    DOI: 10.1074/jbc.274.8.4890

    1998

    Growth and differentiation of the normal mammary gland and its tumours (Journal article)

    Rudland, P. S., Barraclough, R., Fernig, D. G., & Smith, J. A. (1998). Growth and differentiation of the normal mammary gland and its tumours. MAMMARY DEVELOPMENT IN CANCER, (63), 1-20. Retrieved from http://gateway.webofknowledge.com/

    Stem cells in breast epithelia (Journal article)

    Li, P., Barraclough, R., Fernig, D. G., Smith, J. A., & Rudland, P. S. (1998). Stem cells in breast epithelia. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 79(4), 193-206. doi:10.1046/j.1365-2613.1998.00068.x

    DOI: 10.1046/j.1365-2613.1998.00068.x

    Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides (Journal article)

    Kinsella, L., Chen, H. L., Smith, J. A., Rudland, P. S., & Fernig, D. G. (1998). Interactions of putative heparin-binding domains of basic fibroblast growth factor and its receptor, FGFR-1, with heparin using synthetic peptides. GLYCOCONJUGATE JOURNAL, 15(4), 419-422. doi:10.1023/A:1006986104865

    DOI: 10.1023/A:1006986104865

    Hepatocyte growth factor scatter factor has distinct classes of binding site in heparan sulfate from mammary cells (Journal article)

    Rahmoune, H., Rudland, P. S., Gallagher, J. T., & Fernig, D. G. (1998). Hepatocyte growth factor scatter factor has distinct classes of binding site in heparan sulfate from mammary cells. BIOCHEMISTRY, 37(17), 6003-6008. doi:10.1021/bi972468t

    DOI: 10.1021/bi972468t

    Interaction of heparan sulfate from mammary cells with acidic fibroblast growth factor (FGF) and basic FGF - Regulation of the activity of basic FGF by high and low affinity binding sites in heparan sulfate (Journal article)

    Rahmoune, H., Chen, H. L., Gallagher, J. T., Rudland, P. S., & Fernig, D. G. (1998). Interaction of heparan sulfate from mammary cells with acidic fibroblast growth factor (FGF) and basic FGF - Regulation of the activity of basic FGF by high and low affinity binding sites in heparan sulfate. JOURNAL OF BIOLOGICAL CHEMISTRY, 273(13), 7303-7310. doi:10.1074/jbc.273.13.7303

    DOI: 10.1074/jbc.273.13.7303

    Hepatocyte growth factor scatter factor binds with high affinity to dermatan sulfate (Journal article)

    Lyon, M., Deakin, J. A., Rahmoune, H., Fernig, D. G., Nakamura, T., & Gallagher, J. T. (1998). Hepatocyte growth factor scatter factor binds with high affinity to dermatan sulfate. JOURNAL OF BIOLOGICAL CHEMISTRY, 273(1), 271-278. doi:10.1074/jbc.273.1.271

    DOI: 10.1074/jbc.273.1.271

    Ferritin and hemoglobin in pituitary gland extracts are mitogenic for rat mammary epithelial cells in culture (Journal article)

    Wilkinson, M. C., Fernig, D. G., Smith, J. A., de Croker, C. A. N., & Rudland, P. S. (1998). Ferritin and hemoglobin in pituitary gland extracts are mitogenic for rat mammary epithelial cells in culture. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 34(7), 518-519. doi:10.1007/s11626-998-0108-8

    DOI: 10.1007/s11626-998-0108-8

    1997

    Stimulation of proliferation in human colon cancer cells by human monoclonal antibodies against the TF antigen (galactose beta 1-3 N-acetyl-galactosamine) (Journal article)

    Yu, L. G., Jansson, B., Fernig, D. G., Milton, J. D., Smith, J. A., Gerasimenko, O. V., . . . Rhodes, J. M. (1997). Stimulation of proliferation in human colon cancer cells by human monoclonal antibodies against the TF antigen (galactose beta 1-3 N-acetyl-galactosamine). INTERNATIONAL JOURNAL OF CANCER, 73(3), 424-431. doi:3.3.CO;2-C">10.1002/(SICI)1097-0215(19971104)73:3<424::AID-IJC18>3.3.CO;2-C

    DOI: 10.1002/(SICI)1097-0215(19971104)73:3<424::AID-IJC18>3.3.CO;2-C

    Heparin sulphate in breast cancer cells (vol 24, pg 355S, 1996) (Journal article)

    Rahmoune, H., Turnbull, J. E., Gallagher, J. T., Rudland, P. S., & Fernig, D. G. (1997). Heparin sulphate in breast cancer cells (vol 24, pg 355S, 1996). BIOCHEMICAL SOCIETY TRANSACTIONS, 25(4), 1299. Retrieved from http://gateway.webofknowledge.com/

    Programmed cell death in bovine mammary tissue during lactation and involution (Journal article)

    Wilde, C. J., Addey, C. V. P., Li, P., & Fernig, D. G. (1997). Programmed cell death in bovine mammary tissue during lactation and involution. EXPERIMENTAL PHYSIOLOGY, 82(5), 943-953. doi:10.1113/expphysiol.1997.sp004075

    DOI: 10.1113/expphysiol.1997.sp004075

    Invasion of human colorectal carcinoma cells is promoted by endogenous basic fibroblast growth factor (Journal article)

    Galzie, Z., Fernig, D. G., Smith, J. A., Poston, G. J., & Kinsella, A. R. (1997). Invasion of human colorectal carcinoma cells is promoted by endogenous basic fibroblast growth factor. INTERNATIONAL JOURNAL OF CANCER, 71(3), 390-395. doi:3.0.CO;2-K">10.1002/(SICI)1097-0215(19970502)71:3<390::AID-IJC15>3.0.CO;2-K

    DOI: 10.1002/(SICI)1097-0215(19970502)71:3<390::AID-IJC15>3.0.CO;2-K

    Corrections: Heparin sulphate in breast cancer cells (Biochemical Society Transactions (1996) 24,3 (355S)) (Journal article)

    Rahmoune, H., Turnbull, J. E., Gallagher, J. T., Rudland, P. S., & Fernig, D. G. (1997). Corrections: Heparin sulphate in breast cancer cells (Biochemical Society Transactions (1996) 24,3 (355S)). Biochemical Society Transactions, 25(4), 1299.

    1996

    Basic fibroblast growth factor and colorectal carcinoma invasion. (Conference Paper)

    Galzie, Z., Fernig, D. G., Smith, J. A., Poston, G. J., & Kinsella, A. R. (1996). Basic fibroblast growth factor and colorectal carcinoma invasion.. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 24 (pp. S501). doi:10.1042/bst024501s

    DOI: 10.1042/bst024501s

    Heparan sulphate in breast cancer cells (Conference Paper)

    Rahmoune, H., Turnbull, J. E., Gallagher, J. T., Rudland, P. S., & Fernig, D. G. (1996). Heparan sulphate in breast cancer cells. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 24 (pp. S355). doi:10.1042/bst024355s

    DOI: 10.1042/bst024355s

    Identification of cell types in the developing goat mammary gland. (Conference Paper)

    Li, P., Fernig, D. G., Rudland, P. S., Finch, L. M., & Wilde, C. J. (1996). Identification of cell types in the developing goat mammary gland.. In Biochemical Society transactions Vol. 24 (pp. 357S). doi:10.1042/bst024357s

    DOI: 10.1042/bst024357s

    Potentiation of the growth-stimulatory effects of aFGF by heparin in Rama 27 fibroblasts. (Conference Paper)

    Chen, H. L., Smith, J. A., Rudland, P. S., & Fernig, D. G. (1996). Potentiation of the growth-stimulatory effects of aFGF by heparin in Rama 27 fibroblasts.. In Biochemical Society transactions Vol. 24 (pp. 358S). doi:10.1042/bst024358s

    DOI: 10.1042/bst024358s

    Late signals are required for the stimulation of DNA synthesis in rat mammary fibroblasts by growth factors (Journal article)

    Chen, H. L., Rudland, P. S., Smith, J. A., & Fernig, D. G. (1996). Late signals are required for the stimulation of DNA synthesis in rat mammary fibroblasts by growth factors. BIOSCIENCE REPORTS, 16(3), 249-263. doi:10.1007/BF01207339

    DOI: 10.1007/BF01207339

    Effect on tumorigenicity and metastasis of transfection of a diploid benign rat mammary epithelial cell line with DNA corresponding to the mRNA for basic fibroblast growth factor (Journal article)

    Davies, B. R., Fernig, D. G., Barraclough, R., & Rudland, P. S. (1996). Effect on tumorigenicity and metastasis of transfection of a diploid benign rat mammary epithelial cell line with DNA corresponding to the mRNA for basic fibroblast growth factor. INTERNATIONAL JOURNAL OF CANCER, 65(1), 104-111. Retrieved from http://gateway.webofknowledge.com/

    1995

    Activation of basic fibroblast growth factor (bFGF) by heparan sulphate (HS) (Conference Paper)

    CHEN, H. L., RUDLAND, P. S., SMITH, J. A., & FERNIG, D. G. (1995). Activation of basic fibroblast growth factor (bFGF) by heparan sulphate (HS). In INTERCELLULAR SIGNALLING IN THE MAMMARY GLAND (pp. 73-74). Retrieved from http://gateway.webofknowledge.com/

    Fibroblast growth factors in mammary development and cancer (Conference Paper)

    FERNIG, D. G., BARRACLOUGH, R., KE, Y. Q., SMITH, J. A., PLATTHIGGINS, A., WILKINSON, M. C., . . . RUDLAND, P. S. (1995). Fibroblast growth factors in mammary development and cancer. In INTERCELLULAR SIGNALLING IN THE MAMMARY GLAND (pp. 81-82). Retrieved from http://gateway.webofknowledge.com/

    Growth factors and their receptors in neoplastic mammary glands (Journal article)

    Rudland, P. S., Fernig, D. G., & Smith, J. A. (1995). Growth factors and their receptors in neoplastic mammary glands. BIOMEDICINE & PHARMACOTHERAPY, 49(9), 389-399. doi:10.1016/0753-3322(96)82676-X

    DOI: 10.1016/0753-3322(96)82676-X

    1994

    A NOVEL TYROSINE KINASE-ACTIVITY IN THE COTTON LEAFWORM, SPODOPTERA-LITTORALIS (Journal article)

    PEARCE, A., DURKIN, A. F., FISHER, M. J., REES, H. H., TAYLOR, C. F., & FERNIG, D. G. (1994). A NOVEL TYROSINE KINASE-ACTIVITY IN THE COTTON LEAFWORM, SPODOPTERA-LITTORALIS. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 109(2-3), 253-259. doi:10.1016/0305-0491(94)90009-4

    DOI: 10.1016/0305-0491(94)90009-4

    Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair. (Journal article)

    Fernig, D. G., & Gallagher, J. T. (1994). Fibroblast growth factors and their receptors: an information network controlling tissue growth, morphogenesis and repair.. Progress in growth factor research, 5(4), 353-377. doi:10.1016/0955-2235(94)00007-8

    DOI: 10.1016/0955-2235(94)00007-8

    SECRETION OF TRANSFORMING GROWTH-FACTOR-ALPHA AND EXPRESSION OF ITS RECEPTOR IN HUMAN MAMMARY CELL-LINES (Journal article)

    MCANDREW, J., FERNIG, D. G., RUDLAND, P. S., & SMITH, J. A. (1994). SECRETION OF TRANSFORMING GROWTH-FACTOR-ALPHA AND EXPRESSION OF ITS RECEPTOR IN HUMAN MAMMARY CELL-LINES. GROWTH FACTORS, 10(4), 281-287. doi:10.3109/08977199409010994

    DOI: 10.3109/08977199409010994

    1993

    REVERSIBLE INHIBITION OF PROLIFERATION OF EPITHELIAL-CELL LINES BY AGARICUS-BISPORUS (EDIBLE MUSHROOM) LECTIN (Journal article)

    YU, L. G., FERNIG, D. G., SMITH, J. A., MILTON, J. D., & RHODES, J. M. (1993). REVERSIBLE INHIBITION OF PROLIFERATION OF EPITHELIAL-CELL LINES BY AGARICUS-BISPORUS (EDIBLE MUSHROOM) LECTIN. CANCER RESEARCH, 53(19), 4627-4632. Retrieved from http://gateway.webofknowledge.com/

    ECTOPIC PRODUCTION OF HEPARIN-BINDING GROWTH-FACTORS AND RECEPTORS FOR BASIC FIBROBLAST GROWTH-FACTOR BY RAT MAMMARY EPITHELIAL-CELL LINES DERIVED FROM MALIGNANT METASTATIC TUMORS (Journal article)

    FERNIG, D. G., BARRACLOUGH, R., KE, Y. Q., WILKINSON, M. C., RUDLAND, P. S., & SMITH, J. A. (1993). ECTOPIC PRODUCTION OF HEPARIN-BINDING GROWTH-FACTORS AND RECEPTORS FOR BASIC FIBROBLAST GROWTH-FACTOR BY RAT MAMMARY EPITHELIAL-CELL LINES DERIVED FROM MALIGNANT METASTATIC TUMORS. INTERNATIONAL JOURNAL OF CANCER, 54(4), 629-635. doi:10.1002/ijc.2910540418

    DOI: 10.1002/ijc.2910540418

    IMMUNOCYTOCHEMICAL IDENTIFICATION OF BASIC FIBROBLAST GROWTH-FACTOR IN THE DEVELOPING RAT MAMMARY-GLAND - VARIATIONS IN LOCATION ARE DEPENDENT ON GLANDULAR STRUCTURE AND DIFFERENTIATION (Journal article)

    RUDLAND, P. S., PLATTHIGGINS, A. M., WILKINSON, M. C., & FERNIG, D. G. (1993). IMMUNOCYTOCHEMICAL IDENTIFICATION OF BASIC FIBROBLAST GROWTH-FACTOR IN THE DEVELOPING RAT MAMMARY-GLAND - VARIATIONS IN LOCATION ARE DEPENDENT ON GLANDULAR STRUCTURE AND DIFFERENTIATION. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 41(6), 887-898. doi:10.1177/41.6.7686196

    DOI: 10.1177/41.6.7686196

    NORMAL AND MALIGNANT HUMAN COLONIC MUCOSA CONTAIN ACIDIC AND BASIC FIBROBLAST GROWTH-FACTORS (Journal article)

    WILKINSON, M. C., GARDNER, M. J., GOULD, P. W., TAYLOR, B. A., & FERNIG, D. G. (1993). NORMAL AND MALIGNANT HUMAN COLONIC MUCOSA CONTAIN ACIDIC AND BASIC FIBROBLAST GROWTH-FACTORS. INTERNATIONAL JOURNAL OF ONCOLOGY, 3(5), 933-936. Retrieved from http://gateway.webofknowledge.com/

    THE EXPRESSION OF BASIC FIBROBLAST GROWTH-FACTOR AND ITS RECEPTOR IN CELL-LINES DERIVED FROM NORMAL HUMAN MAMMARY-GLAND AND A BENIGN MAMMARY LESION (Journal article)

    KE, Y. Q., FERNIG, D. G., WILKINSON, M. C., WINSTANLEY, J. H. R., SMITH, J. A., RUDLAND, P. S., & BARRACLOUGH, R. (1993). THE EXPRESSION OF BASIC FIBROBLAST GROWTH-FACTOR AND ITS RECEPTOR IN CELL-LINES DERIVED FROM NORMAL HUMAN MAMMARY-GLAND AND A BENIGN MAMMARY LESION. JOURNAL OF CELL SCIENCE, 106, 135-143. Retrieved from http://gateway.webofknowledge.com/

    1992

    A RAPID PROCEDURE FOR PRODUCTION OF HUMAN BASIC FIBROBLAST GROWTH-FACTOR IN ESCHERICHIA-COLI-CELLS (Journal article)

    KE, Y. Q., WILKINSON, M. C., FERNIG, D. G., SMITH, J. A., RUDLAND, P. S., & BARRACLOUGH, R. (1992). A RAPID PROCEDURE FOR PRODUCTION OF HUMAN BASIC FIBROBLAST GROWTH-FACTOR IN ESCHERICHIA-COLI-CELLS. BIOCHIMICA ET BIOPHYSICA ACTA, 1131(3), 307-310. doi:10.1016/0167-4781(92)90029-Y

    DOI: 10.1016/0167-4781(92)90029-Y

    IDENTIFICATION OF THE BASIC FIBROBLAST GROWTH-FACTOR BINDING SEQUENCE IN FIBROBLAST HEPARAN-SULFATE (Journal article)

    TURNBULL, J. E., FERNIG, D. G., KE, Y. Q., WILKINSON, M. C., & GALLAGHER, J. T. (1992). IDENTIFICATION OF THE BASIC FIBROBLAST GROWTH-FACTOR BINDING SEQUENCE IN FIBROBLAST HEPARAN-SULFATE. JOURNAL OF BIOLOGICAL CHEMISTRY, 267(15), 10337-10341. Retrieved from http://gateway.webofknowledge.com/

    Rat Mammary Myoepithelial-Like Cells in Culture Possess Kinetically Distinct Low-Affinity Receptors for Fibroblast Growth Factor That Modulate Growth Stimulatory Responses (Journal article)

    Fernig, D. G., Rudland, P. S., & Smith, J. A. (1992). Rat Mammary Myoepithelial-Like Cells in Culture Possess Kinetically Distinct Low-Affinity Receptors for Fibroblast Growth Factor That Modulate Growth Stimulatory Responses. GROWTH FACTORS, 7(1), 27-39. doi:10.3109/08977199209023935

    DOI: 10.3109/08977199209023935

    1991

    Relationship of growth factors and differentiation in normal and neoplastic development of the mammary gland. (Journal article)

    Fernig, D. G., Smith, J. A., & Rudland, P. S. (1991). Relationship of growth factors and differentiation in normal and neoplastic development of the mammary gland.. Cancer treatment and research, 53, 47-78. doi:10.1007/978-1-4615-3940-7_3

    DOI: 10.1007/978-1-4615-3940-7_3

    1990

    HIGH-LEVEL PRODUCTION OF HUMAN ACIDIC FIBROBLAST GROWTH-FACTOR IN ESCHERICHIA-COLI-CELLS - INHIBITION OF DNA-SYNTHESIS IN RAT MAMMARY FIBROBLASTS AT HIGH-CONCENTRATIONS OF GROWTH-FACTOR (Journal article)

    KE, Y. Q., FERNIG, D. G., SMITH, J. A., WILKINSON, M. C., ANANDAPPA, S. Y., RUDLAND, P. S., & BARRACLOUGH, R. (1990). HIGH-LEVEL PRODUCTION OF HUMAN ACIDIC FIBROBLAST GROWTH-FACTOR IN ESCHERICHIA-COLI-CELLS - INHIBITION OF DNA-SYNTHESIS IN RAT MAMMARY FIBROBLASTS AT HIGH-CONCENTRATIONS OF GROWTH-FACTOR. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 171(3), 963-971. doi:10.1016/0006-291X(90)90778-L

    DOI: 10.1016/0006-291X(90)90778-L

    APPEARANCE OF BASIC FIBROBLAST GROWTH-FACTOR RECEPTORS UPON DIFFERENTIATION OF RAT MAMMARY EPITHELIAL TO MYOEPITHELIAL-LIKE CELLS IN CULTURE (Journal article)

    FERNIG, D. G., SMITH, J. A., & RUDLAND, P. S. (1990). APPEARANCE OF BASIC FIBROBLAST GROWTH-FACTOR RECEPTORS UPON DIFFERENTIATION OF RAT MAMMARY EPITHELIAL TO MYOEPITHELIAL-LIKE CELLS IN CULTURE. JOURNAL OF CELLULAR PHYSIOLOGY, 142(1), 108-116. doi:10.1002/jcp.1041420114

    DOI: 10.1002/jcp.1041420114

    SYNTHESIS OF BASIC FIBROBLAST GROWTH-FACTOR UPON DIFFERENTIATION OF RAT MAMMARY EPITHELIAL TO MYOEPITHELIAL-LIKE CELLS IN CULTURE (Journal article)

    BARRACLOUGH, R., FERNIG, D. G., RUDLAND, P. S., & SMITH, J. A. (1990). SYNTHESIS OF BASIC FIBROBLAST GROWTH-FACTOR UPON DIFFERENTIATION OF RAT MAMMARY EPITHELIAL TO MYOEPITHELIAL-LIKE CELLS IN CULTURE. JOURNAL OF CELLULAR PHYSIOLOGY, 144(2), 333-344. doi:10.1002/jcp.1041440220

    DOI: 10.1002/jcp.1041440220

    1989

    INSULIN PROCESSING IN PRIMARY ENDOSOMES IS NOT RESPONSIBLE FOR INSULIN RESISTANCE OBSERVED IN PARAMETRIAL ADIPOCYTES FROM LACTATING RATS (Journal article)

    FERNIG, D. G., & MAYER, R. J. (1989). INSULIN PROCESSING IN PRIMARY ENDOSOMES IS NOT RESPONSIBLE FOR INSULIN RESISTANCE OBSERVED IN PARAMETRIAL ADIPOCYTES FROM LACTATING RATS. BIOCHIMICA ET BIOPHYSICA ACTA, 1010(2), 237-245. doi:10.1016/0167-4889(89)90167-5

    DOI: 10.1016/0167-4889(89)90167-5

    IDENTIFICATION OF ALPHA TRANSFORMING GROWTH-FACTOR AS A POSSIBLE LOCAL TROPHIC AGENT FOR THE MAMMARY-GLAND (Journal article)

    SMITH, J. A., BARRACLOUGH, R., FERNIG, D. G., & RUDLAND, P. S. (1989). IDENTIFICATION OF ALPHA TRANSFORMING GROWTH-FACTOR AS A POSSIBLE LOCAL TROPHIC AGENT FOR THE MAMMARY-GLAND. JOURNAL OF CELLULAR PHYSIOLOGY, 141(2), 362-370. doi:10.1002/jcp.1041410218

    DOI: 10.1002/jcp.1041410218

    1987

    DEGRADATION OF NUCLEAR PROTEINS - STUDIES ON TRANSPLANTED B82 CELL KARYOPLAST PROTEINS (Journal article)

    FERNIG, D. G., & MAYER, R. J. (1987). DEGRADATION OF NUCLEAR PROTEINS - STUDIES ON TRANSPLANTED B82 CELL KARYOPLAST PROTEINS. FEBS LETTERS, 210(2), 165-168. doi:10.1016/0014-5793(87)81329-7

    DOI: 10.1016/0014-5793(87)81329-7

    1986

    INTRACELLULAR PROTEIN CATABOLISM - EVIDENCE FOR SEQUESTRATION OF PROTEINS INTO AN INTERMEDIATE-FILAMENT FRACTION BEFORE LYSOSOMAL DEGRADATION (Journal article)

    MAYER, R. J., GASKELL, M. J., EARL, R., BILLETT, E. E., MANGIAPANE, H. E., FERNIG, D., & DOHERTY, F. J. (1986). INTRACELLULAR PROTEIN CATABOLISM - EVIDENCE FOR SEQUESTRATION OF PROTEINS INTO AN INTERMEDIATE-FILAMENT FRACTION BEFORE LYSOSOMAL DEGRADATION. BIOMEDICA BIOCHIMICA ACTA, 45(11-12), 1591-1602. Retrieved from http://gateway.webofknowledge.com/

    1985

    Intracellular degradative fate of transplanted and microinjected proteins. (Journal article)

    Mayer, R. J., Russell, S. M., Amenta, J. S., Evans, P. J., Fernig, D., & Doherty, F. (1985). Intracellular degradative fate of transplanted and microinjected proteins.. Progress in clinical and biological research, 180, 395-404.