Professor Ainhoa Mielgo Iza
Professor in Cancer Biology Molecular & Clinical Cancer Medicine
- +44 (0)151 794 9555
- Work email A.Mielgo@liverpool.ac.uk
- Personal Websitehttp://mielgolab.org/
Research
Tumour-stroma interactions
Dr Ainhoa Mielgo’s laboratory focuses on investigating how tumour cells interact with the non-cancerous cells that surround cancer cells, that include fibroblasts and immune cells and form the tumour stroma. The tumour stroma plays a key role in cancer progression, metastasis and resistance to therapies. Ainhoa's team is interested in understanding the complex crosstalk between stromal, immune and tumour cells with the aim to identify physiologically relevant targets and develop more effective treatments for cancer patients. To achieve this goal, her laboratory uses a combination of innovative technologies established in her lab, including pre-clinical tumour models, patient samples, co-culture cell-based assays, quantitative proteomics, scRNA sequencing, bioinformatics, and flow and mass cytometry.
Drug resistance & Metastasis
Tumour immunity
Research Grants
Assessing Gas6+ neutrophils in the blood of pancreatic cancer patients undergoing chemotherapy to generate evidence for targeting Gas6/AXL signalling in patients
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
September 2023 - March 2025
Research fees for Maidinaimu Abudula 201450341
CHINA SCHOLARSHIP COUNCIL (CSC)(CHINA) 🚩
October 2021 - September 2024
Function of stroma-derived gas6 in pancreatic cancer progression and metastasis.
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)
December 2019 - November 2023
Studying the impact of a non-canonical CRAF/PLK1 signalling pathway in desmoplasia and pancreatic cancer progression
WELLCOME TRUST (UK)
April 2014 - December 2019
Role of monocytes in the metastatic process: identification of novel molecular targets to fight pancreatic cancer
PANCREATIC CANCER RESEARCH FUND (UK)
July 2015 - June 2019
Multi-modal high resolution preclinical PET+SPECT+CT scanner
WELLCOME TRUST (UK)
July 2018 - June 2024
Bench fees for Mr Sufyan M A El Hashani 201182871
LIBYAN EMBASSY IN LONDON🚩
October 2020 - September 2024