Portfolio
Clinical Trial of Investigational Medicinal Products (CTIMP)
| Study | Topic | Population | Design | Website |
| TORPEDO-CF | Pseudomonas Eradication | Paediatric - Cystic Fibrosis | RCT | Visit Website |
| SYCAMORE | Adalumimab in paediatric uveitis secondary to juvenile idiopathic arthritis | Paediatric - Arthritis | RCT | Visit Website |
| MYPAN | Mycophenolate mofetil versus cyclophosphamide for polyarteritis nodosa | Paediatric - Polyarteritis | RCT | |
| HUMOX | Humidified oxygen versus standard oxygen therapy | Paediatric - Asthma | Pilot | |
| SANAD-II | Standard and New Anti-epileptic Drugs | Adult/Paediatric - Epilepsy | RCT | |
| TAILOR | TelmisArtan and InsuLin Resistance in HIV | Adults - HIV | RCT | Visit Website |
| ECLIPSE | Emergency treatment with LevetIracetam or Phenytoin in Status Epilepticus | Paediatric | RCT | Visit Website |
| OVERT | Botulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A randomised controlled trial | Paediatric | RCT | |
| PROTEKT | Phase IIa, Randomised, Controlled, OpenLabel Trial of Rosuvastatin for the Prevention of AminoglycosideInduced Kidney Toxicity in Children with Cystic Fibrosis | Paediatric | RCT | Visit Website |
| TREAT | Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial | Paediatric | RCT | Visit Website |
| APTITUDE | APTITUDE A phase II trial of Tocilizumab in anti-TNF refractory patients with JIA associated uveitis | Paediatric | RCT | Visit Website |
| DEX ENCEPH | COrticosteroids in Herpes SImplex Virus Encephalitis | Adult/Paediatric | Visit Website | |
| RAPID | Phase IIb, randomised, double-blind placebo- controlled, multi-centre trial of infliximab with transcriptomic biomarker and mechanism evaluation in patients with acute pancreatitis | Adult (18-85) | Randomised, double-blind, placebo-controlled, multicentre trial, employing and adaptive design with two interim analyses | Visit Website |
| PIROUETTE | A double-blind randomised controlled trial of Pirfenidone in patients with heart failure and preserved ejection fraction | Adults – heart failure | RCT | Visit Website |
| CHERRY | Feasibility Study on the effects of L-Citrulline on uteroplacental and Cardiovascular function in hypertensive pregnant women | Pregnant Women | Double-blinded, randomised- controlled feasibility study |
Non -CTIMP Clinical Trials
| Study | Topic | Population | Design | Website |
| SAFE | Seizure first aid training for epilepsy (pilot) | Epilepsy | Pilot | Visit Website |
| EDIBLE | Epilepsy - Strategies to improve diagnosis, prevention and treatment | Paediatric - Epilepsy | Visit Website | |
| ISDR | Screening for diabetic retinopathy | Adults - Diabetes | RCT | visit website |
| DENTALRECUR | Primary care service to reduce the re-occurrence of childhood dental caries | Adult / Paediatric - Dental | RCT | Visit Website |
| ENCEPH | Encephalitis -implementation of guidelines | Adult / Paediatric - Encephalitis | Cohort and Cluster RCT | Visit Website |
| SLUMBRS | Sleep position in cleft babies (SLUMBERS) feasibility | Paediatric | RCT | |
| ACORN | Improving oral health in cleft lip and/or palate: A health promotion | Paediatric | Health Promotion | |
| REACT | An online randomised controlled trial to evaluate the clinical and cost effectiveness of the Relatives Education And Coping Toolkit (REACT) | Adult | RCT | Visit Website |
| FOUNDATION | Feasibility study of a trial of bilateral cochlear implantation in adults | Adults with profound deafness | Feasibility Study | Visit Website |
| NAMASTE | The Namaste Care intervention to improve the quality of dying for people with advanced dementia living in care homes: A realist review and feasibility study for cluster randomised controlled trial | Adults with advanced dementia | Feasibility study for a cluster randomised controlled trial | Visit Website |
Surgical Clinical Trials (Including devices)
| Study | Topic | Population | Design | Website |
| TOPS-CP | Timing of Primary Surgery for Cleft Palate | Paediatric - Cleft Palate | RCT | Visit Website |
| BASICS | Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts | Paediatric - Hydrocephalus | RCT | visit website |
| NERVES | Transforaminal epidural steroid injection to surgical microdiscectomy for the treatment of acute lumbar radicular pain | Adult | RCT | Visit Website |
Devices Clinical Trials
| Study | Topic | Population | Design | Website |
| PREVAIL | Preventing Infection using Antibiotic Impregnated Long Lines | Paediatric | Open two-arm, multi-centre RCT | visit website |
Research Methodology
| Study | Topic | Population | Design | Website |
| EPIC | Optimise methods for involving patient and public representatives in clinical trials: a systematic investigation of a cohort of Health Technology Assessment funded clinical trials | PPI | Cohort | Visit Website |
Other Research Designs
| Study | Topic | Population | Design | Website |
| ReaDySpeech for people with dysarthria after stroke: a feasibility study. ADD | Feasibility | |||
| Core outcome set for anal cancer studies ADD | Core Outcome Set | |||
| Neighbourhoods and Dementia ADD | Core Outcome Set | |||
| IVIS | Impact of Visual Impairment after Stroke (IVIS) | Vision | Visit Website | |
| ROAM | Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial) | Adult (16+) | Open two-arm, multi-centre RCT | Visit Website |
| BOSS | British Orthopaedic Surgery and Surveillance Study | Paediatric | Prospective Cohort Study | Visit Website |
| NOVEMBR | Non-invasive ventilation in the management of children with bronchiolitis: A feasibility study | Paediatric- bronchiolitis | Feasibility, Delphi | Visit Website |
Contact:
Jo Gardner
Administrator
Clinical Trials Research Centre
2nd Floor
Institute in the Park
Alder Hey Children’s Hospital
L12 2AP
0151 795 8751