Liverpool Reviews and Implementation Group

What we do

We primarily conduct reviews of the clinical and cost effectiveness of health technologies. This includes:

  • Health technology: any device, drug, equipment or procedure utilised to promote health, prevent or treat disease, improve rehabilitation or long-term care.
  • Health technology assessment: methods for considering clinical effectiveness, cost effectiveness and contextual matters (health policy, equality, ethics, dissemination).
  • Systematic review: determining clinical effectiveness of health technologies (how well care works) and placing the results in context for healthcare practitioners or researchers.
  • Economic evaluation: undertaking cost-effectiveness analysis of health technologies (how much value is achieved by a form of care, and at what cost, relative to alternatives). Cost effectiveness is an important consideration of healthcare practitioners, managers and policy makers.

The National Institute for Health and Care Excellence

In England and Wales, The National Institute for Health and Care Excellence (NICE) produces guidance on the use of new technologies for use in the NHS, as well as guidelines for clinical practice which focus on specific diseases or medical conditions.

NICE depends on the National Institute for Health Research Health Technology Assessment Programme (NIHR HTA) to provide independent, high-quality reviews of evidence on which to base its guidance. This usually takes the form of a Technology Assessment Review, commissioned by NIHR HTA and conducted by one of nine Evidence Review Groups, such as ours.

Technology Assessment Reviews can take the form of either multiple technology assessment or single technology assessment reports. It takes 24 weeks to produce a multiple technology assessment report, and 8 weeks for a single technology assessment report, although the process from start to finish is much longer.

Read more about these processes

Although the Technology Assessment reports are sent to NICE, it is the Appraisal Committee’s role to determine if, and how, health technologies are to be implemented by the NHS. The appraisal process is not purely scientific; it also includes considerations of policy, ethics and implementation and is conducted separately from the assessment process.


‘Evidence Synthesis’ is a key strength of researchers, academics and healthcare professionals working along the North West Coast (NWC).  We are a key partner in the Collaboration for Leadership in Applied Health Research and Care North West Coast, and we lend our expertise in encouraging, facilitating and supporting specific requests for evidence synthesis from CLAHRC stakeholders, partners and themes to inform policy and/or develop future research projects.

For more information on our involvement with CLAHRC, please follow this link.