Anne Marshall Spotlight
Main research interests
Investigating the contribution of the peripheral and central nervous system in pain generation and pain modulation. This work encompasses the use of neurophysiology, corneal confocal microscopy and quantitative sensory testing.
Biography
My current role is within the Neuropathy Research Group, as research associate on the DEFINE-FMS study. The primary aim of the study is to determine the contribution of small fibre neuropathy in Fibromyalgia syndrome (FMS) and explore the relationship between small nerve fibre structural alterations, small nerve fibre function and neuropathic pain phenotypes. I also contribute to studies investigating neuropathic pain in idiopathic, chemotherapy induced and diabetic neuropathy.
Additionally, I am a member of the research team investigating synaptic plasticity, specifically long-term potentiation and long-term depression as underpinning mechanisms in the development and potential treatment of neuropathic pain following nerve injury.
I am in the process of finalising my PhD at the University of Manchester: Investigating spinally mediated pain and H-reflex rate dependent depression (HRDD) as a potential biomarker of spinal disinhibition in patients with diabetic neuropathy.