PhD Studentships of the North West Cancer Research (NWCR) Centre

The NWCR Centre comprises a network research groups from across the NW of England who work on basic and translational aspects of cancer biology.

The following three full-funded PhD projects are available for commencing October 2019:

  1. Defining and drugging the role of BAP1-mutation in the invasive behaviour of mesothelioma and uveal melanoma.
    Supervisor: Prof Judy Coulson (University of Liverpool)

  2. How is the immune system alerted to persistent replication stress and DNA damage in keratinocytes during immunosurveillance against cutaneous squamous cell carcinoma?
    Supervisor: Dr Leonie Unterholzner (Lancaster University)

  3. Cancer Proteomics: Deciphering the cellular targets of clinical protein kinase inhibitors
    Supervisor: Prof Pat Eyers (University of Liverpool).

Research environment

This is a combined program supported by NWCR and the Universities of Liverpool, Lancaster and Bangor. We have considerable experience in providing high quality Ph.D. training based on the exceptionally strong research expertise within the Centre. Work at the NWCR Centre is supported by international centres of excellence, including the: NWCR Institute - University of Bangor, Division of Biomedical and Life Sciences, Lancaster University, MRC Centre for Drug Safety Science, Wolfson Centre for Personalised Medicine, Centre for Genomic Research, Centre for Preclinical Imaging, LBIH Biobank, Instrumentation available through the Technology Directorate, UoL.

Eligibility and funding

The NWCR Centre will support three students with three year studentships (currently starting at £19,000 per annum, tax free), course fees (home/EU rate), travel and research funds. Applicants must have (or be predicted to obtain) the equivalent of a first or upper second class degree in a relevant subject. UK and EU students are eligible.

Qualifications and Experience

Applicants should be recent graduates or final year undergraduates who have to get a first or upper second-class honours degree or equivalent, and have laboratory or research experience (either as part of or outside of a university degree course). All applicants must satisfy the appropriate University English language requirements (IELTS score of 6.5). You will be expected to be able to work both in a team and independently and develop expertise in new areas as required.
Travel expenses for interview will be covered but candidates from non-EU countries are required to pay their own travel expenses.

How to Apply

To apply please send a covering letter, full Curriculum Vitae and the name, addresses and telephone numbers of two referees to Ideally, they will be academic/industry lab heads that have direct experience of your research capabilities. Please indicate which project(s) you are interested in being considered for. For general application enquires please contact Debbie Horne, NWCR-UoL Centre Administrator.

Note that interviews are to be scheduled for the second half of January 2019.

Please note that due to the large volume of applications received, it is not possible for acknowledgements to be provided for each application.

Deadline: Friday 7th December 2018. 

October 2014

Miss Lucy Ireland
Identification and validation of signalling pathways regulating desmoplasia and pancreatic cancer progression
Supervisor: Dr Ainhoa Mielgo (University of Liverpool)

Miss Erithelgi Bertsoulaki
Development of cellular models to quantitatively profile ALK-kinase signalling in neuroblastoma
Supervisor: Professor Mike Clague (University of Liverpool)

Miss Valaria Quaranta
Investigating the pathophysiological changes in myeloid immune cells that promote pancreatic cancer metastasis
Supervisor: Dr Michael Schmid (University of Liverpool)

October 2016

Miss Terpsi Vitti
Proton beam therapy in head and neck squamous cell carcinoma and uveal melanoma
Supervisor: Dr Jason Parsons (University of Liverpool)

Miss Angharad Wilkie
Investigation of therapy-induced ciliogenesis, and a novel dual regulator of ciliogenesis and DNA repair
Supervisor: Dr Chris Staples (Bangor University)

October 2017

Mr Sean Duffy
Proteomics Meets Cancer Therapeutics: Comprehensive Analysis of Cellular Drug Interactions in CML using Mass Spectrometry-based Thermal Proteomic Profiling
Supervisor: Dr Pat Eyers (University of Liverpool)

Miss Ottilie Swinyard
Molecular analysis of Ap4A-mediated regulation of DNA replication and genome stability
Supervisor: Dr. Nikki Copeland (University of Lancaster)

Ms Claire Kelly
Magnetic resonance spectroscopy and imaging markers for identification of IDH mutation and grading of gliomas
Supervisor: Professor Harish Poptani and Dr Violaine See (University of Liverpool)

October 2018

Nicole Simms
Function of cancer-associated fibrosis in regulating tumour immunity and response to immunotherapy
Supervisor: Dr Michael Schmid (University of Liverpool)

Tobias Bunday
Assessment of the efficacy and safety of a novel pharmacological strategy designed to enhance liver regeneration following tumour resection.
Supervisor: Dr Ian Copple (University of Liverpool)