2023
Influence of highly effective modulator therapy on the sputum proteome in cystic fibrosis. (Journal article)
Maher, R. E., Barry, P. J., Emmott, E., Jones, A. M., Lin, L., McNamara, P. S., . . . Lord, R. W. (2023). Influence of highly effective modulator therapy on the sputum proteome in cystic fibrosis.. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, S1569-1993(23)01669-7. doi:10.1016/j.jcf.2023.10.019DOI: 10.1016/j.jcf.2023.10.019
Sposito, F., Northey, S., Charras, A., McNamara, P. S., & Hedrich, C. M. (2023). Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome.. Genes and immunity. doi:10.1038/s41435-023-00218-7DOI: 10.1038/s41435-023-00218-7
Sposito, F., Pennington, S. H., A W David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. M. (2023). Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.. Mucosal immunology, S1933-0219(23)00064-8. doi:10.1016/j.mucimm.2023.08.002DOI: 10.1016/j.mucimm.2023.08.002
Fyles, F., Hill, H., Duncan, G., Carter, E., Solorzano, C., Davies, K., . . . Collins, A. M. (2023). Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings in Merseyside, Cheshire and Bristol, UK. BMJ OPEN RESPIRATORY RESEARCH, 10(1). doi:10.1136/bmjresp-2022-001457DOI: 10.1136/bmjresp-2022-001457
FitzMaurice, T. S., McCann, C., Nazareth, D., Hawkes, S., Shaw, M., McNamara, P. S., & Walshaw, M. (2023). Feasibility of dynamic chest radiography to calculate lung volumes in adult people with cystic fibrosis: a pilot study. BMJ OPEN RESPIRATORY RESEARCH, 10(1). doi:10.1136/bmjresp-2022-001309DOI: 10.1136/bmjresp-2022-001309
Characterising the effect of body mass index on thoracic mechanics in adults with cystic fibrosis using dynamic chest radiography (Conference Paper)
FitzMaurice, T. S., McCann, C., Nazareth, D., Walshaw, M., & McNamara, P. S. (2023). Characterising the effect of body mass index on thoracic mechanics in adults with cystic fibrosis using dynamic chest radiography. In RESPIROLOGY Vol. 28 (pp. 145-146). Retrieved from https://www.webofscience.com/
2022
Maher, R. E., Barrett, E., Beynon, R. J., Harman, V. M., Jones, A. M., McNamara, P. S., . . . Lord, R. W. (2022). The relationship between lung disease severity and the sputum proteome in cystic fibrosis. RESPIRATORY MEDICINE, 204. doi:10.1016/j.rmed.2022.107002DOI: 10.1016/j.rmed.2022.107002
Saint, G. L., Thomas, M. F., Zainal Abidin, N., Langley, R. J., Brodlie, M., & McNamara, P. (n.d.). Treating nontuberculous mycobacteria in children with cystic fibrosis: a multicentre retrospective study. Archives of Disease in Childhood. doi:10.1136/archdischild-2021-322177DOI: 10.1136/archdischild-2021-322177
Quantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis (Journal article)
Maher, R. E., Maatta, M., Beynon, R. J., Laurila, H. P., McNamara, P. S., & Rajamaki, M. M. (2022). Quantitative proteomic analysis of bronchoalveolar lavage fluid in West Highland white terriers with canine idiopathic pulmonary fibrosis. BMC VETERINARY RESEARCH, 18(1). doi:10.1186/s12917-022-03202-xDOI: 10.1186/s12917-022-03202-x
FitzMaurice, T. S., McCann, C., Nazareth, D. S., McNamara, P. S., & Walshaw, M. J. (2022). Use of Dynamic Chest Radiography to Assess Treatment of Pulmonary Exacerbations in Cystic Fibrosis.. Radiology, 212641. doi:10.1148/radiol.212641DOI: 10.1148/radiol.212641
Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., Compton, V., Fernandes, R. M., . . . McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), e052943. doi:10.1136/bmjopen-2021-052943DOI: 10.1136/bmjopen-2021-052943
McNamara, P. S., Clayton, D., Burchett, C., Compton, V., Peak, M., Clark, J., & Jones, A. P. (2022). Humidified and standard oxygen therapy in acute severe asthma in children (HUMOX): A pilot randomised controlled trial.. PloS one, 17(2), e0263044. doi:10.1371/journal.pone.0263044DOI: 10.1371/journal.pone.0263044
FitzMaurice, T. S., McCann, C., Nazareth, D., Shaw, M., McNamara, P. S., & Walshaw, M. J. (2022). Measuring the effect of elexacaftor/tezacaftor/ivacaftor combination therapy on the respiratory pump in people with CF using dynamic chest radiography. Journal of Cystic Fibrosis. doi:10.1016/j.jcf.2022.01.007DOI: 10.1016/j.jcf.2022.01.007
2021
Shrwani, K., Sharma, R., Krishnan, M., Jones, T., Mayora-Neto, M., Cantoni, D., . . . Zhang, Q. (2021). Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post-COVID-19 Convalescent Samples. JOURNAL OF INFECTIOUS DISEASES, 224(8), 1305-1315. doi:10.1093/infdis/jiab333DOI: 10.1093/infdis/jiab333
Early Life Respiratory Infection (Chapter)
Patel, L. B., Legg, J. P., & McNamara, P. S. (2022). Early Life Respiratory Infection. In Encyclopedia of Respiratory Medicine (pp. 110-118). Elsevier. doi:10.1016/b978-0-08-102723-3.00195-5DOI: 10.1016/b978-0-08-102723-3.00195-5
2020
Sposito, F., McNamara, P. S., & Hedrich, C. M. (2020). Vasculitis in Cystic Fibrosis. FRONTIERS IN PEDIATRICS, 8. doi:10.3389/fped.2020.585275DOI: 10.3389/fped.2020.585275
Rosala-Hallas, A., Jones, A. P., Bedson, E., Compton, V., Fernandes, R. M., Lacy, D., . . . McNamara, P. S. (2020). National survey of feasibility of NIV trials for management of children with bronchiolitis.. BMJ Paediatrics Open, 4(1), e000780. doi:10.1136/bmjpo-2020-000780DOI: 10.1136/bmjpo-2020-000780
Modified Vaccinia Ankara–Vectored Vaccine Expressing Nucleoprotein and Matrix Protein 1 (M1) Activates Mucosal M1-Specific T-Cell Immunity and Tissue-Resident Memory T Cells in Human Nasopharynx-Associated Lymphoid Tissue (Journal article)
Puksuriwong, S., Ahmed, M. S., Sharma, R., Krishnan, M., Leong, S., Lambe, T., . . . Zhang, Q. (2020). Modified Vaccinia Ankara–Vectored Vaccine Expressing Nucleoprotein and Matrix Protein 1 (M1) Activates Mucosal M1-Specific T-Cell Immunity and Tissue-Resident Memory T Cells in Human Nasopharynx-Associated Lymphoid Tissue. The Journal of infectious diseases, 222(5), 807-819. doi:10.1093/infdis/jiz593DOI: 10.1093/infdis/jiz593
Löwensteyn, Y. N., Phijffer, E. W. E. M., Simons, J. V. L., Scheltema, N. M., Mazur, N. I., Nair, H., & Bont, L. J. (2020). Respiratory Syncytial Virus-related Death in Children With Down Syndrome. Pediatric Infectious Disease Journal, 39(8), 665-670. doi:10.1097/inf.0000000000002666DOI: 10.1097/inf.0000000000002666
Tripp, R. A., & McNamara, P. S. (2020). Pathobiology of Respiratory Syncytial Virus (RSV).. Vaccines, 8(3). doi:10.3390/vaccines8030367DOI: 10.3390/vaccines8030367
Felsenstein, S., Herbert, J. A., McNamara, P. S., & Hedrich, C. M. (2020). COVID-19: Immunology and treatment options. CLINICAL IMMUNOLOGY, 215. doi:10.1016/j.clim.2020.108448DOI: 10.1016/j.clim.2020.108448
FitzMaurice, T. S., McNamara, P. S., Nazareth, D., McCann, C., Bedi, R., Shaw, M., & Walshaw, M. (2020). Utility and validity of dynamic chest radiography in cystic fibrosis (dynamic CF): an observational, non-controlled, non-randomised, single-centre, prospective study.. BMJ Open Respir Res, 7(1). doi:10.1136/bmjresp-2020-000569DOI: 10.1136/bmjresp-2020-000569
2019
Nikolaou, E., Blizard, A., Pojar, S., Mitsi, E., German, E. L., Reine, J., . . . Jochems, S. P. (2019). Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 38(11), 1147-1149. doi:10.1097/INF.0000000000002454DOI: 10.1097/INF.0000000000002454
O'Toole, D. P. H., Latchford, G. J., Duff, A. J. A., Ball, R., McCormack, P., McNamara, P. S., . . . Southern, K. W. (2019). Adherence to Aerosol Therapy in Young People With Cystic Fibrosis: Patient and Parent Perspectives Following Electronic Data Capture. QUALITATIVE HEALTH RESEARCH, 29(6), 846-856. doi:10.1177/1049732318805754DOI: 10.1177/1049732318805754
Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry (Journal article)
Gardner, A. I., McClenaghan,, E., Saint, G., Mcnamara, P. S., Brodlie, M., & Thomas, M. F. (2019). Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry. Clinical Infectious Diseases, 68(05), 731-737. doi:10.1093/cid/ciy531DOI: 10.1093/cid/ciy531
Dunning, J., Blankley, S., Hoang, L. T., Cox, M., Graham, C. M., James, P. L., . . . Griffiths, M. J. (2019). Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018). NATURE IMMUNOLOGY, 20(3), 373. doi:10.1038/s41590-019-0328-yDOI: 10.1038/s41590-019-0328-y
Saint, G. L., Hawcutt, D. B., & McNamara, P. S. (2019). Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study.. Thorax. doi:10.1136/thoraxjnl-2018-212625DOI: 10.1136/thoraxjnl-2018-212625
2018
van Miert, C., Fernandes, R. M., Eccleson, H., Bedson, E., Lane, S., Peak, M., . . . McNamara, P. S. (2018). Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol. TRIALS, 19. doi:10.1186/s13063-018-2969-9DOI: 10.1186/s13063-018-2969-9
Alturaiki, W., McFarlane, A. J., Rose, K., Corkhill, R., McNamara, P. S., Schwarze, J., & Flanagan, B. F. (2018). Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection. CYTOKINE, 110, 267-271. doi:10.1016/j.cyto.2018.01.014DOI: 10.1016/j.cyto.2018.01.014
Roper, L., Sherratt, F., Young, B., Mcnamara, P., Dawson, A., Appleton, R., . . . Woolfall, K. (2018). Children’s views on research without prior consent in emergency situations: aUK qualitative study. BMJ Open, 8(6). doi:10.1136/bmjopen-2018-022894DOI: 10.1136/bmjopen-2018-022894
Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response (Journal article)
Aljurayyan, A., Puksuriwong, S., Ahmed, M., Sharma, R., Krishnan, M., Sood, S., . . . Zhang, Q. (2018). Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response. Journal of virology, 92(11). doi:10.1128/jvi.00114-18DOI: 10.1128/jvi.00114-18
Dunning, J., Blankley, S., Hoang, L. T., Cox, M., Graham, C. M., James, P. L., . . . Openshaw, P. J. M. (2018). Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza. Nature Immunology, 19(06), 625-635. doi:10.1038/s41590-018-0111-5DOI: 10.1038/s41590-018-0111-5
Thorburn, K., Fulton, C., King, C., Ramaneswaran, D., Alammar, A., & McNamara, P. S. (2018). Transaminase levels reflect disease severity in children ventilated for respiratory syncytial virus (RSV) bronchiolitis. SCIENTIFIC REPORTS, 8. doi:10.1038/s41598-018-20292-6DOI: 10.1038/s41598-018-20292-6
Fonceca, A. M., Zosky, G. R., Bozanich, E. M., Sutanto, E. N., Kicic, A., McNamara, P. S., . . . Stick, S. M. (2018). Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung. RESPIRATORY RESEARCH, 19. doi:10.1186/s12931-017-0701-zDOI: 10.1186/s12931-017-0701-z
2017
Gangadharan, A., McCoy, P., Phyo, A., McGuigan, M. P., Dharmaraj, P., Ramakrishnan, R., & McNamara, P. S. (2017). Recovery of hypothalamo–pituitary–adrenal axis suppression during treatment with inhaled corticosteroids for childhood asthma. Journal of Asthma and Allergy, 2017(10), 317-326. doi:10.2147/JAA.S142874DOI: 10.2147/JAA.S142874
Giri, D., Vignola, M. L., Gualtieri, A., Scagliotti, V., McNamara, P., Peak, M., . . . Senniappan, S. (2017). Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities. HUMAN MOLECULAR GENETICS, 26(22), 4315-4326. doi:10.1093/hmg/ddx318DOI: 10.1093/hmg/ddx318
Giri, D., Rigden, D., Didi, M., Peak, M., McNamara, P., & Senniappan, S. (2017). Novel compound heterozygous <i>ASXL3</i> mutation causing Bainbridge-ropers like syndrome and primary IGF1 deficiency. INTERNATIONAL JOURNAL OF PEDIATRIC ENDOCRINOLOGY. doi:10.1186/s13633-017-0047-9DOI: 10.1186/s13633-017-0047-9
Irwin, A. D., Grant, A., Williams, R., Kolamunnage-Dona, R., Drew, R. J., Paulus, S., . . . Carrol, E. D. (2017). Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department. Pediatrics, 140(2), 0. doi:10.1542/peds.2016-2853DOI: 10.1542/peds.2016-2853
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza (Journal article)
Cole, S. L., Dunning, J., Kok, W. L., Benam, K. H., Benlahrech, A., Repapi, E., . . . Ho, L. -P. (2017). M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. JCI INSIGHT, 2(7). doi:10.1172/jci.insight.91868DOI: 10.1172/jci.insight.91868
2016
A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA (Journal article)
Aljurayyan, A. N., Sharma, R., Upile, N., Beer, H., Vaughan, C., Xie, C., . . . Zhang, Q. (2016). A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA. ANTIVIRAL RESEARCH, 132, 122-130. doi:10.1016/j.antiviral.2016.05.021DOI: 10.1016/j.antiviral.2016.05.021
Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells (Journal article)
Hackett, A. M., Trinick, R. E., Rose, K., Flanagan, B. F., & McNamara, P. S. (2016). Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells. Respiratory Research, 17. doi:10.1186/s12931-016-0399-3DOI: 10.1186/s12931-016-0399-3
Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue <i>in vitro</i> by Modified Vaccinia Ankara-vectored influenza vaccines (Journal article)
Mullin, J., Ahmed, M. S., Sharma, R., Upile, N., Beer, H., Achar, P., . . . Zhang, Q. (2016). Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue <i>in vitro</i> by Modified Vaccinia Ankara-vectored influenza vaccines. VACCINE, 34(14), 1688-1695. doi:10.1016/j.vaccine.2016.02.028DOI: 10.1016/j.vaccine.2016.02.028
Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis (Conference Paper)
Saint, G. L., Smyth, R., Flanagan, B. F., & McNamara, P. S. (2016). Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 193. Retrieved from https://www.webofscience.com/
Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil (Journal article)
Fawkner-Corbett, D. W., Khoo, S. K., Duarte, C. M., Bezerra, P. G. M., Bochkov, Y. A., Gern, J. E., . . . McNamara, P. S. (2016). Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil. JOURNAL OF MEDICAL VIROLOGY, 88(1), 58-63. doi:10.1002/jmv.24300DOI: 10.1002/jmv.24300
2015
Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial? (Journal article)
Gaillard, E. A., McNamara, P. S., Murray, C. S., Pavord, I. D., & Shields, M. D. (2015). Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial?. CLINICAL AND EXPERIMENTAL ALLERGY, 45(9), 1384-1395. doi:10.1111/cea.12535DOI: 10.1111/cea.12535
Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review (Journal article)
Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Dixon, S., . . . Cross, E. (2015). Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review. HEALTH TECHNOLOGY ASSESSMENT, 19(66), 1-+. doi:10.3310/hta19660DOI: 10.3310/hta19660
Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus (Journal article)
Habibi, M. S., Jozwik, A., Makris, S., Dunning, J., Paras, A., The Mechanisms of Severe Acute Influenza Consortium Investigators., . . . Chiu, C. (2015). Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(9), 1040-1049. doi:10.1164/rccm.201412-2256OCDOI: 10.1164/rccm.201412-2256OC
An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability (Journal article)
Trinick, R. E., Bunni, L., Thorburn, K., Hackett, A. P., Dalzell, M., & McNamara, P. S. (2015). An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability. PLOS ONE, 10(4). doi:10.1371/journal.pone.0124627DOI: 10.1371/journal.pone.0124627
Irwin, A., Drew, R. J., Marshall, P., Nguyen, K., Hoyle, E., Macfarlane, K. A., . . . Carrol, E. (2015). Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department. Pediatrics, 135(4), 635-642. doi:10.1542/peds.2014-2061DOI: 10.1542/peds.2014-2061
Ahmed, M. S., Jacques, L. C., Mahallawi, W., Ferrara, F., Temperton, N., Upile, N., . . . Zhang, Q. (2015). Cross-reactive immunity against influenza viruses in children and adults following 2009 pandemic H1N1 infection. ANTIVIRAL RESEARCH, 114, 106-112. doi:10.1016/j.antiviral.2014.12.008DOI: 10.1016/j.antiviral.2014.12.008
2014
SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis (Journal article)
Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Cooper, C. L., . . . Team, S. A. B. R. E. S. (2014). SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. THORAX, 69(12), 1105-1112. doi:10.1136/thoraxjnl-2014-205953DOI: 10.1136/thoraxjnl-2014-205953
Turnover of strains and intraclonal variation amongst <i>Pseudomonas aeruginosa</i> isolates from paediatric CF patients (Journal article)
Hall, A. J., Fothergill, J. L., McNamara, P. S., Southern, K. W., & Winstanley, C. (2014). Turnover of strains and intraclonal variation amongst <i>Pseudomonas aeruginosa</i> isolates from paediatric CF patients. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 80(4), 324-326. doi:10.1016/j.diagmicrobio.2014.09.007DOI: 10.1016/j.diagmicrobio.2014.09.007
Elderfield, R. A., Watson, S. J., Godlee, A., Adamson, W. E., Thompson, C. I., Dunning, J., . . . Barclay, W. S. (2014). Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom. JOURNAL OF VIROLOGY, 88(22), 13269-13283. doi:10.1128/JVI.01636-14DOI: 10.1128/JVI.01636-14
Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol (Journal article)
van Miert, C., Abbott, J., Verheoff, F., Lane, S., Carter, B., & McNamara, P. (2014). Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol. JOURNAL OF ADVANCED NURSING, 70(10), 2353-2362. doi:10.1111/jan.12387DOI: 10.1111/jan.12387
Lees, E., Carrol, E., Gerrard, C., Hardiman, F., Howel, G., Timmis, A., . . . McNamara, P. (2014). Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens. BMC Infectious Diseases, 14. doi:10.1186/1471-2334-14-343DOI: 10.1186/1471-2334-14-343
Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014). THE B LYMPHOCYTE DIFFERENTIATION FACTOR (BAFF) IS EXPRESSED IN THE AIRWAYS OF CHILDREN WITH CF AND IN LUNGS OF MICE INFECTED WITH PSEUDOMONAS AERUGINOSA. PLoS One, 9(5). doi:10.1371/journal.pone.0095892.DOI: 10.1371/journal.pone.0095892.
Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage (Journal article)
Gray, C., Ahmed, M. S., Mubarak, A., Kasbekar, A. V., Derbyshire, S., McCormick, M. S., . . . Zhang, Q. (2014). Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage. MUCOSAL IMMUNOLOGY, 7(3), 705-717. doi:10.1038/mi.2013.89DOI: 10.1038/mi.2013.89
Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection (Conference Paper)
Flanagan, B., McFarlane, A., Al-Turaiki, W., Fitch, P., Slupsky, J., McNamara, P. S., & Schwarze, J. (2014). Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/
Bronchiolitis (Chapter)
Thorburn, K., & McNamara, P. S. (2014). Bronchiolitis. In Pediatric Critical Care Medicine (pp. 75-85). Springer London. doi:10.1007/978-1-4471-6356-5_5DOI: 10.1007/978-1-4471-6356-5_5
Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria (Conference Paper)
Bezerra, P. G. D. M., Duarte, M. M. B., McNamara, P. S., Britto, M. A. D., Rose, K., Cuevas, L. E., . . . Correia, J. D. B. (2014). Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/
Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus (Conference Paper)
Duarte, M. M. B., McNamara, P. S., Bezerra, P. G. D. M., Britto, M. A. D., Cuevas, L. E., Rose, K., . . . Correia, J. D. B. (2014). Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/
Respiratory Symptoms Increase With Increasing Neurodisability (Conference Paper)
Bunni, L., Turner, L., Mohamed, S., & McNamara, P. S. (2014). Respiratory Symptoms Increase With Increasing Neurodisability. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/
Respiratory Syncytial Virus Is Taken Up By Neutrophils And Can Be Visualised By Confocal Microscopy Throughout The Cytoplasm (Conference Paper)
Saint, G. L., Smyth, R. L., Flanagan, B. F., & McNamara, P. S. (2014). Respiratory Syncytial Virus Is Taken Up By Neutrophils And Can Be Visualised By Confocal Microscopy Throughout The Cytoplasm. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from https://www.webofscience.com/
2013
Respiratory Viruses and Atypical Bacteria (Chapter)
McNamara, P. S., & Van Doorn, H. R. (2014). Respiratory Viruses and Atypical Bacteria. In Manson's Tropical Infectious Diseases (pp. 215-224.e2). Elsevier. doi:10.1016/b978-0-7020-5101-2.00020-0DOI: 10.1016/b978-0-7020-5101-2.00020-0
Comparison of real time diagnostic chemistries to detect <i>Pseudomonas aeruginosa</i> in respiratory samples from cystic fibrosis patients (Journal article)
Fothergill, J. L., Ledson, M. J., Walshaw, M. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Comparison of real time diagnostic chemistries to detect <i>Pseudomonas aeruginosa</i> in respiratory samples from cystic fibrosis patients. JOURNAL OF CYSTIC FIBROSIS, 12(6), 675-681. doi:10.1016/j.jcf.2013.04.007DOI: 10.1016/j.jcf.2013.04.007
THE DEVELOPMENT AND VALIDATION OF A CLINICAL SEVERITY SCORE FOR INFANTS WITH BRONCHIOLITIS (Conference Paper)
van Miert, C., Abbott, J., Verhoeff, F., Lane, S., Carter, B., & McNamara, P. S. (2013). THE DEVELOPMENT AND VALIDATION OF A CLINICAL SEVERITY SCORE FOR INFANTS WITH BRONCHIOLITIS. In THORAX Vol. 68 (pp. A40-A41). doi:10.1136/thoraxjnl-2013-204457.82DOI: 10.1136/thoraxjnl-2013-204457.82
Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time (Journal article)
Ball, R., Southern, K. W., McCormack, P., Duff, A. J. A., Brownlee, K. G., & McNamara, P. S. (2013). Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time. JOURNAL OF CYSTIC FIBROSIS, 12(5), 440-444. doi:10.1016/j.jcf.2012.12.012DOI: 10.1016/j.jcf.2012.12.012
Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses. (Journal article)
Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses.. Journal of virology, 87(10), 5331-5339. doi:10.1128/jvi.03547-12DOI: 10.1128/jvi.03547-12
Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa. (Journal article)
Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa.. Journal of medical microbiology, 62(Pt 2), 208-216. doi:10.1099/jmm.0.048272-0DOI: 10.1099/jmm.0.048272-0
After a long wait, two arrive, one after the other! (Journal article)
Southern, K. W., McCormack, P., & McNamara, P. S. (2013). After a long wait, two arrive, one after the other!. THORAX, 68(4), 311-312. doi:10.1136/thoraxjnl-2012-202891DOI: 10.1136/thoraxjnl-2012-202891
Changes in inflammatory cytokine production by airway epithelial cells in response to mild acidification and LPS stimulation under acidic conditions (Conference Paper)
Hackett, A. P., Flanagan, B. F., & McNamara, P. S. (2013). Changes in inflammatory cytokine production by airway epithelial cells in response to mild acidification and LPS stimulation under acidic conditions. In IMMUNOLOGY Vol. 140 (pp. 83). Retrieved from https://www.webofscience.com/
Induction of Th17 in nasopharynx-associated lymphoid tissue by pneumococcus and the effect of IL-21 and IL-15 (Conference Paper)
Mubarak, A. S., Kasbekar, A., McCormick, M., Beer, H., Cunliffe, N., McNamara, P. S., & Zhang, Q. (2013). Induction of Th17 in nasopharynx-associated lymphoid tissue by pneumococcus and the effect of IL-21 and IL-15. In IMMUNOLOGY Vol. 140 (pp. 105). Retrieved from https://www.webofscience.com/
Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses (Journal article)
Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses. JOURNAL OF VIROLOGY, 87(10), 5331-5339. doi:10.1128/JVI.03547-12DOI: 10.1128/JVI.03547-12
Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of <i>Pseudomonas aeruginosa</i> (Journal article)
Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of <i>Pseudomonas aeruginosa</i>. JOURNAL OF MEDICAL MICROBIOLOGY, 62, 208-216. doi:10.1099/jmm.0.048272-0DOI: 10.1099/jmm.0.048272-0
Investigating the mechanism of interaction between neutrophils and virus in Respiratory Syncytial Virus (RSV) disease (Conference Paper)
Saint, G. L., Flanagan, B. F., McNamara, P. S., & Smyth, R. L. (2013). Investigating the mechanism of interaction between neutrophils and virus in Respiratory Syncytial Virus (RSV) disease. In IMMUNOLOGY Vol. 140 (pp. 83-84). Retrieved from https://www.webofscience.com/
Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF (Journal article)
McNamara, P. S., Fonceca, A. M., Howarth, D., Correia, J. B., Slupsky, J. R., Trinick, R. E., . . . Flanagan, B. F. (2013). Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF. THORAX, 68(1), 76-81. doi:10.1136/thoraxjnl-2012-202288DOI: 10.1136/thoraxjnl-2012-202288
2012
New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis (Journal article)
McCormack, P., Southern, K. W., & McNamara, P. S. (2012). New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis. JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 25(6), 307-309. doi:10.1089/jamp.2011.0934DOI: 10.1089/jamp.2011.0934
The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil. (Journal article)
Fawkner-Corbett, D. W., Duarte, M. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil.. The Pediatric infectious disease journal, 31(6), 653-655. doi:10.1097/inf.0b013e3182501ff4DOI: 10.1097/inf.0b013e3182501ff4
Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis (Journal article)
Trinick, R., Southern, K. W., & McNamara, P. S. (2012). Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis. EUROPEAN RESPIRATORY JOURNAL, 39(4), 899-905. doi:10.1183/09031936.00070311DOI: 10.1183/09031936.00070311
IFITM3 restricts the morbidity and mortality associated with influenza (Journal article)
Everitt, A. R., Clare, S., Pertel, T., John, S. P., Wash, R. S., Smith, S. E., . . . Kellam, P. (2012). IFITM3 restricts the morbidity and mortality associated with influenza. NATURE, 484(7395), 519-U146. doi:10.1038/nature10921DOI: 10.1038/nature10921
Reply to Kahn (Journal article)
Halfhide, C. P., Flanagan, B. F., Brearey, S. P., Hunt, J. A., Fonceca, A. M., McNamara, P. S., . . . Smyth, R. L. (2012). Reply to Kahn. Journal of Infectious Diseases, 205(4), 693-694. doi:10.1093/infdis/jir823DOI: 10.1093/infdis/jir823
Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection (Journal article)
Fonceca, A. M., Flanagan, B. F., Trinick, R., Smyth, R. L., & McNamara, P. S. (2012). Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection. THORAX, 67(1), 42-48. doi:10.1136/thoraxjnl-2011-200131DOI: 10.1136/thoraxjnl-2011-200131
Reflux aspiration in children with neurodisability-a significant problem, but can we measure it? (Journal article)
Trinick, R., Johnston, N., Dalzell, A. M., & McNamara, P. S. (2012). Reflux aspiration in children with neurodisability-a significant problem, but can we measure it?. JOURNAL OF PEDIATRIC SURGERY, 47(2), 291-298. doi:10.1016/j.jpedsurg.2011.11.019DOI: 10.1016/j.jpedsurg.2011.11.019
THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL (Journal article)
Fawkner-Corbett, D. W., Duarte, M. D. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 31(6), 653-655. doi:10.1097/INF.0b013e3182501ff4DOI: 10.1097/INF.0b013e3182501ff4
2011
A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis (Journal article)
McCormack, P., McNamara, P. S., & Southern, K. W. (2011). A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 10(5), 343-349. doi:10.1016/j.jcf.2011.04.006DOI: 10.1016/j.jcf.2011.04.006
Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization (Journal article)
Zhang, Q., Leong, S. C., McNamara, P. S., Mubarak, A., Malley, R., & Finn, A. (2011). Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization. PLOS PATHOGENS, 7(8). doi:10.1371/journal.ppat.1002175DOI: 10.1371/journal.ppat.1002175
Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years (Journal article)
Bezerra, P. G. M., Britto, M. C. A., Correia, J. B., Duarte, M. D. C. M. B., Fonceca, A. M., Rose, K., . . . McNamara, P. S. (2011). Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years. PLOS ONE, 6(4). doi:10.1371/journal.pone.0018928DOI: 10.1371/journal.pone.0018928
Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains. (Journal article)
Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2011). Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains.. Journal of Cystic Fibrosis, 10 (S1, S32.
2010
Microarray genotyping of Pseudomonas aeruginosa isolates from CF units. (Journal article)
Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2010). Microarray genotyping of Pseudomonas aeruginosa isolates from CF units.. Journal of Cystic Fibrosis, 9(S1), S30.
2009
Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis (Journal article)
McNamara, P. S., McCormack, P., McDonald, A. J., Heaf, L., & Southern, K. W. (2009). Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 8(4), 258-263. doi:10.1016/j.jcf.2009.04.006DOI: 10.1016/j.jcf.2009.04.006
A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic. (Journal article)
Morris, D., Fallon, L., Heaf, L., Burrows, E. F., Wallace, H., McNamara, P. S., . . . Southern, K. W. (2009). A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic.. Ped Pulmonol, 32, 325.
2008
Comparison of techniques for obtaining lower airway epithelial cells from children (Journal article)
McNamara, P. S., Kicic, A., Sutanto, E. N., Stevens, P. T., & Stick, S. M. (2008). Comparison of techniques for obtaining lower airway epithelial cells from children. EUROPEAN RESPIRATORY JOURNAL, 32(3), 763-768. doi:10.1183/09031936.00162507DOI: 10.1183/09031936.00162507
2007
Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis (Journal article)
McNamara, P. S., Flanagan, B. F., Smyth, R. L., & Hart, C. A. (2007). Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis. PEDIATRIC PULMONOLOGY, 42(8), 740-743. doi:10.1002/ppul.20649DOI: 10.1002/ppul.20649
2005
Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease (Journal article)
McNamara, P. S., & Smyth, R. L. (2005). Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease. DRUG NEWS & PERSPECTIVES, 18(10), 615-621. doi:10.1358/dnp.2005.18.10.959575DOI: 10.1358/dnp.2005.18.10.959575
Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis (Journal article)
McNamara, P. S., Flanagan, B. F., Hart, C. A., & Smyth, R. L. (2005). Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(8), 1225-1232. doi:10.1086/428855DOI: 10.1086/428855
Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis (Journal article)
Semple, M. G., Cowell, A., Dove, W., Greensill, J., McNamara, P. S., Halfhide, C., . . . Hart, C. A. (2005). Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(3), 382-386. doi:10.1086/426457DOI: 10.1086/426457
2004
Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis (Journal article)
McNamara, P. S., Flanagan, B. F., Baldwin, L. M., Newland, P., Hart, C. A., & Smyth, R. L. (2004). Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis. LANCET, 363(9414), 1031-1037. doi:10.1016/S0140-6736(04)15838-8DOI: 10.1016/S0140-6736(04)15838-8
Cytokines in severe Respiratory Syncytial Virus bronchiolitis (Thesis / Dissertation)
McNamara, P. S. (2004). Cytokines in severe Respiratory Syncytial Virus bronchiolitis. (PhD Thesis, The University of Liverpool).
Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis (Journal article)
McNamara, P. S., Flanagan, B. F., Selby, A. M., Hart, C. A., & Smyth, R. L. (2004). Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis. EUROPEAN RESPIRATORY JOURNAL, 23(1), 106-112. doi:10.1183/09031936.03.00048103DOI: 10.1183/09031936.03.00048103
2003
Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis (Journal article)
McNamara, P. S., Ritson, P., Selby, A., Hart, C. A., & Smyth, R. L. (2003). Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis. ARCHIVES OF DISEASE IN CHILDHOOD, 88(10), 922-926. doi:10.1136/adc.88.10.922DOI: 10.1136/adc.88.10.922
Human metapneumovirus in severe respiratory syncytial virus bronchiolitis (Journal article)
Greensill, J., McNamara, P. S., Dove, W., Flanagan, B., Smyth, R. L., & Hart, C. A. (2003). Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. EMERGING INFECTIOUS DISEASES, 9(3), 372-375. doi:10.3201/eid0903.020289DOI: 10.3201/eid0903.020289
2002
A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children (Journal article)
Powell, C. V. E., McNamara, P., Solis, A., & Shaw, N. J. (2002). A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children. ARCHIVES OF DISEASE IN CHILDHOOD, 87(5), 376-379. doi:10.1136/adc.87.5.376DOI: 10.1136/adc.87.5.376
The pathogenesis of respiratory syncytial virus disease in childhood (Journal article)
McNamara, P. S., & Smyth, R. L. (2002). The pathogenesis of respiratory syncytial virus disease in childhood. BRITISH MEDICAL BULLETIN, 61, 13-28. doi:10.1093/bmb/61.1.13DOI: 10.1093/bmb/61.1.13
2001
Headache and abdominal pain (Journal article)
McNamara, P. S., Mallucci, C. L., & Appleton, R. T. (2001). Headache and abdominal pain. LANCET, 357(9260), 930. doi:10.1016/S0140-6736(00)04215-XDOI: 10.1016/S0140-6736(00)04215-X