Em P James Gallagher B.Sc., M.Sc., Ph.D.

Professor Musculoskeletal & Ageing Science

Research

Research Interest 1

Cell and molecular biology of bone.

Research Grants

Bone anabolic effects of low dose parathyroid hormone.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

October 2005 - September 2006

ICAC (Integrated Clinical Arthritis Centre) Grant.

ARTHRITIS RESEARCH CAMPAIGN

April 2002 - October 2004

Investigating the mechanisms of ATP release and interconversion from osteoblasts.

ARTHRITIS RESEARCH CAMPAIGN

May 2006 - January 2010

Regulation of P2Y receptor-mediated Ca2+ transients by membrane potential in arterial smooth muscle cells.

BRITISH HEART FOUNDATION (UK)

February 2005 - January 2007

Investigation of how extracellular nucleotides synergise with growth factors to stimulate gene expression, cell proliferation and neoplastic progression

NORTH WEST CANCER RESEARCH FUND

April 1998 - December 2001

Find AKUre.

THE ALKAPTONURIA SOCIETY (UK)

May 2009 - May 2013

ATPBone—Fighting osteoporosis by blocking nucleotides: purinergic signalling in bone formation and homeostasis

EUROPEAN COMMISSION

January 2008 - December 2010

Establishment of an advanced electron microscopy unit.

WELLCOME TRUST (UK)

August 2004 - October 2009

The Pathogenesis of Tissue Damage in Alkaptonuria

THE ALKAPTONURIA SOCIETY (UK)

August 2006 - August 2007

High resolution analysis of phenotype in manipulated complex tissues.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

November 2003 - November 2004

A preclinical feasibility study using recombinant homogentisic acid dehydrogenase as an enzyme replacement therapy for Alkaptonuria

WELLCOME TRUST (UK)

June 2014 - May 2015

Nociceptive purinergic P2X receptors in equine laminae and nerves – potential molecular targets for treating laminitis

PET PLAN CHARITABLE TRUST (UK)

October 2009 - September 2010

Effects of ultrasound on ATP release from human osteoblasts in vitro.

WRIGHTINGTON, WIGAN AND LEIGH NHS FOUNDATION TRUST (UK)

March 2005 - August 2005

ATP Binding Cassette (ABC) Transporters in Bone.

MEDICAL RESEARCH COUNCIL

September 2000 - August 2003

Academic Secretary Grant.

ARTHRITIS RESEARCH CAMPAIGN

April 1999 - April 2002

Investigation of the Mechanisms of Synergy and Consequences of Co-activation of Osteoblasts by Parathyroid Hormone and Extracellular Nucleotides.

ARTHRITIS RESEARCH CAMPAIGN

December 2001 - January 2005

Alkaptonuria PhD student

THE ALKAPTONURIA SOCIETY (UK)

October 2007 - March 2011

DevelopAKUre - Clinical Development of Nitisinone for Alkaptonuria

EUROPEAN COMMISSION

November 2012 - January 2019

Investigation of isoform-specific effects of PTHrP (1-173) in human osteoblasts.

ACTION MEDICAL RESEARCH (UK)

December 1998 - December 2001

Initiating events in the pigmentation of connective tissues that is the basis of the genetic disease Alkaptonuria

CHILDWICK TRUST

January 2013 - December 2015

Advanced Study of AKU in the Hgd-/-Mouse

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

July 2014 - December 2020

Administration of B.N.A.

BRITISH NEUROSCIENCE ASSOCIATION (UK)

October 1997 - August 2011

The expression and functional significance of P2 receptor subtypes in normal and pathological bone.

ARTHRITIS RESEARCH CAMPAIGN

October 1999 - September 2004

Assessment of Ochronosis in Ear Biopsies in AKU Patients

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

June 2012 - December 2025

Assessment of Disease Progress in the Rare Disease Alkaptonuria by Quantitative Image Analysis

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

November 2014 - June 2020

Research Collaborations

Gallagher

Internal