COPE Study

COPE Study - £1.8m for major new study into bleeding after childbirth

Post-Partum Haemorrhage (PPH) Butterfly

A development study funded by the NiHR Invention for Innovation (i4i) programme. Sponsored by University of Liverpool

Principal Objective: To recruit up to 10 healthy volunteers (who have just given birth) in order to test the usability/suitability of a novel medical device. Developed by the Chief Investigator (Weeks) this novel medical device may significantly contribute towards an acceptable solution for management of PPH.

Visit the PPH Butterfly website.

The University of Liverpool in the UK will work with Gynuity Health Projects (www.gynuity.org) in New York, USA and the Government Medical College in Nagpur to run the MOLI study in three sites in Nagpur, India. The study seeks to explore whether augmentation using oral misoprostol is superior to the standard protocol of intravenous oxytocin in Indian women who have undergone cervical preparation with oral misoprostol as part of labour induction for hypertensive disease. The primary outcome is the rate of caesarean birth, but the study will also consider satisfaction and cost. The study seeks to recruit 1000 women across the three sites.

INFORM study

Researchers from the University with colleagues from Gynuity Health Care in New York and the Government Medial College, Nagpur, India, have published a major study of two different types of labour induction methods in The Lancet.

Principal objective: Between 62 000 and 77 000 women die annually from pre-eclampsia and eclampsia. Prompt delivery, preferably by the vaginal route, is vital for good maternal and neonatal outcomes. Two low-cost interventions—low-dose oral misoprostol tablets and transcervical Foley catheterisation—are already used in low-resource settings. We aimed to compare the relative risks and benefits of these interventions.

AIMS study

Effectiveness of antibiotic prophylaxis during surgical evacuation of the uterus for miscarriage management in low income countries: a multinational, randomised, double-blind placebo-controlled trial (Aims Study)

Funded by the MRC, Sponsored by the University of Birmingham, this multi-centre study is run across sites in low resources settings including Mbale, Uganda, through the Sanyu Africa Research Institute (SAfRI)

Principal Objective: To test the hypothesis that in women having miscarriage surgery, pre-surgery prophylactic antibiotics (oral doxycycline 400mg and oral metronidazole 400mg) reduces the risk of pelvic infection within 14 days of surgery.

Pilot study of a cluster randomised trial of the provision of alcohol hand gel to postpartum mothers to prevent neonatal infective morbidity in the home. 

Dr. Achier Akol

“A prospective study of the diagnostic role of ultrasound amongst women with retained placentas“

Dr. Abiola Aiyenigba

This includes the development of a CBT based counselling intervention called FELICIA (FErtility LIfe Counselling In Africa.)”