Molecular Biology and Mechanisms of Disease
Group Leader
Prof Luminita ParaoanLuminita.Paraoan@liverpool.ac.uk
Prof Luminita ParaoanLuminita.Paraoan@liverpool.ac.uk
Our research aims to further the understanding of fundamental molecular processes and pathways underlying physiology of various eye tissues in health, ageing and degeneration.
Studying gene expression and regulation in pigmented cells of the eye (retinal pigment epithelial, trabecular meshwork, uveal melanocytes) and focusing on fundamental cellular processes of proteolysis, apoptosis and cellular signalling, the group has identified and characterised key molecular determinants of normal and pathological states of specific eye tissues. The findings have relevance for major eye diseases (age-related macular degeneration, proliferative vitreoretinal disease, uveal melanoma and glaucoma) and wider implications for age-related degenerative processes, proliferative pathology and cancer. Through this we can support progress in their diagnosis and treatment.
Out and about … November 2019. Luminita with (left to right) Umar Sharif, Lewis Kelly, Dhanach Dhirachaikulpanich, Neil Saptarshi, Kaiyue Teng, Kasit Chatsirisupachai, Emil Carlsson.
Luminita with (l to r) Kaiyue Teng, Wasu Supharattanasitthi, Samantha McDonnell, Neil Saptarshi, Emil Carlsson, Umar Sharif, Sean Duffy – November 2018
December 2017 - Ocular Molecular Biology and Mechanisms of Disease Group
Welcoming visitors from Thailand and Germany in the new labs, May 2017. First Winter in Apex II 2015 |
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Together in the office at the end of 2014.
In the lab...
... and with the Royal Hospital Lamb Banana.
Bowling team represented by 3 continents (Asia, Europe and South America), 3 European countries (Germany, Romania and UK) and 3 UK counties (Merseyside, Greater Manchester and West Yorkshire).