2021
Edogbanya, J., Tejada-Martinez, D., Jones, N. J., Jaiswal, A., Bell, S., Cordeiro, R., . . . de Magalhaes, J. P. (2021). Evolution, structure and emerging roles of C1ORF112 in DNA replication, DNA damage responses, and cancer. CELLULAR AND MOLECULAR LIFE SCIENCES, 78(9), 4365-4376. doi:10.1007/s00018-021-03789-8DOI: 10.1007/s00018-021-03789-8
2020
Ferguson, F., McLennan, A. G., Urbaniak, M. D., Jones, N. J., & Copeland, N. A. (2020). Re-evaluation of Diadenosine Tetraphosphate (Ap<sub>4</sub>A) From a Stress Metabolite to <i>Bona Fide</i> Secondary Messenger. FRONTIERS IN MOLECULAR BIOSCIENCES, 7. doi:10.3389/fmolb.2020.606807DOI: 10.3389/fmolb.2020.606807
Paredes, R., Kelly, J. R., Geary, B., Almarzouq, B., Schneider, M., Pearson, S., . . . Meyer, S. (2020). EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal. CELL DEATH & DISEASE, 11(10). doi:10.1038/s41419-020-03099-0DOI: 10.1038/s41419-020-03099-0
Guerra, J., Valadao, A. -L., Vlachakis, D., Polak, K., Vila, I. K., Taffoni, C., . . . Laguette, N. (2020). Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation. SCIENCE ADVANCES, 6(21). doi:10.1126/sciadv.aax3333DOI: 10.1126/sciadv.aax3333
2017
Cossar, L. H., Schache, A. G., Risk, J. M., Sacco, J. J., Jones, N. J., & Lord, R. (2017). Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer. Clinical Oncology, 29(9), 626-634. doi:10.1016/j.clon.2017.03.002DOI: 10.1016/j.clon.2017.03.002
2016
NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap(4)A) and Down-Regulates Immune Response and Cancer Promotion Genes (Journal article)
Marriott, A. S., Vasieva, O., Fang, Y., Copeland, N. A., McLennan, A. G., & Jones, N. J. (2016). NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap(4)A) and Down-Regulates Immune Response and Cancer Promotion Genes. PLOS ONE, 11(5). doi:10.1371/journal.pone.0154674DOI: 10.1371/journal.pone.0154674
2015
Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication (Journal article)
Marriott, A. S., Copeland, N. A., Cunningham, R., Wilkinson, M. C., McLennan, A. G., & Jones, N. J. (2015). Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication. DNA REPAIR, 33, 90-100. doi:10.1016/j.dnarep.2015.06.008DOI: 10.1016/j.dnarep.2015.06.008
2014
The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and Regulate Each Other's Chromatin Localization (Journal article)
Chen, X., Wilson, J. B., McChesney, P., Williams, S. A., Kwon, Y., Longerich, S., . . . Kupfer, G. M. (2014). The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and Regulate Each Other's Chromatin Localization. JOURNAL OF BIOLOGICAL CHEMISTRY, 289(37), 25774-25782. doi:10.1074/jbc.M114.552570DOI: 10.1074/jbc.M114.552570
2011
Functional and physical interaction between the mismatch repair and FA-BRCA pathways. (Journal article)
Williams, S. A., Wilson, J. B., Clark, A. P., Mitson-Salazar, A., Tomashevski, A., Ananth, S., . . . Kupfer, G. M. (2011). Functional and physical interaction between the mismatch repair and FA-BRCA pathways.. Human molecular genetics, 20(22), 4395-4410. doi:10.1093/hmg/ddr366DOI: 10.1093/hmg/ddr366
Statistical Association of Basal Cell Keratins with Metastasis-Inducing Proteins in a Prognostically Unfavorable Group of Sporadic Breast Cancers (Journal article)
Rudland, S. D. S., Platt-Higgins, A., Winstanley, J. H. R., Jones, N. J., Barraclough, R., West, C., . . . Rudland, P. S. (2011). Statistical Association of Basal Cell Keratins with Metastasis-Inducing Proteins in a Prognostically Unfavorable Group of Sporadic Breast Cancers. AMERICAN JOURNAL OF PATHOLOGY, 179(2), 1061-1072. doi:10.1016/j.ajpath.2011.04.022DOI: 10.1016/j.ajpath.2011.04.022
2010
Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. (Journal article)
Wilson, J. B., Blom, E., Cunningham, R., Xiao, Y., Kupfer, G. M., & Jones, N. J. (2010). Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.. Mutation research, 689(1-2), 12-20. doi:10.1016/j.mrfmmm.2010.04.003DOI: 10.1016/j.mrfmmm.2010.04.003
Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response. (Journal article)
Thompson, L. H., & Jones, N. J. (2010). Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response.. Molecular cell, 37(6), 749-751. doi:10.1016/j.molcel.2010.03.003DOI: 10.1016/j.molcel.2010.03.003
Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer (Journal article)
Rudland, P. S., Platt-Higgins, A. M., Davies, L. M., Rudland, S. D. S., Wilson, J. B., Aladwani, A., . . . Jones, N. J. (2010). Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer. AMERICAN JOURNAL OF PATHOLOGY, 176(6), 2935-2947. doi:10.2353/ajpath.2010.090779DOI: 10.2353/ajpath.2010.090779
2009
Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. (Journal article)
Zhi, G., Wilson, J. B., Chen, X., Krause, D. S., Xiao, Y., Jones, N. J., & Kupfer, G. M. (2009). Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.. Cancer research, 69(22), 8775-8783. doi:10.1158/0008-5472.can-09-2312DOI: 10.1158/0008-5472.can-09-2312
ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. (Journal article)
Collins, N. B., Wilson, J. B., Bush, T., Thomashevski, A., Roberts, K. J., Jones, N. J., & Kupfer, G. M. (2009). ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function.. Blood, 113(10), 2181-2190. doi:10.1182/blood-2008-05-154294DOI: 10.1182/blood-2008-05-154294
Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links. (Journal article)
Wu, J. H., Wilson, J. B., Wolfreys, A. M., Scott, A., & Jones, N. J. (2009). Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links.. Mutagenesis, 24(2), 173-181. doi:10.1093/mutage/gen068DOI: 10.1093/mutage/gen068
2008
FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 (Journal article)
Wilson, J. B., Yamamoto, K., Marriott, A. S., Hussain, S., Sung, P., Hoatlin, M. E., . . . Jones, N. J. (2008). FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. ONCOGENE, 27(26), 3641-3652. doi:10.1038/sj.onc.1211034DOI: 10.1038/sj.onc.1211034
2006
Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2 (Journal article)
Hussain, S., Wilson, J. B., Blom, E., Thompson, L. H., Sung, P., Gordon, S. M., . . . Jones, N. J. (2006). Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. DNA REPAIR, 5(5), 629-640. doi:10.1016/j.dnarep.2006.02.007DOI: 10.1016/j.dnarep.2006.02.007
2005
How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery. (Journal article)
Thompson, L. H., Hinz, J. M., Yamada, N. A., & Jones, N. J. (2005). How Fanconi anemia proteins promote the four Rs: replication, recombination, repair, and recovery.. Environmental and molecular mutagenesis, 45(2-3), 128-142. doi:10.1002/em.20109DOI: 10.1002/em.20109
New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant (Journal article)
Tebbs, R. S., Hinz, J. M., Yamada, N. A., Wilson, J. B., Salazar, E. P., Thomas, C. B., . . . Thompson, L. H. (2005). New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant. DNA Repair, 4, 11-22. Retrieved from http://www.sciencedirect.com/
2004
Relative sensitivities of repair-deficient mammalian cells for clonogenic survival after alpha-particle irradiation. (Journal article)
Hill, M. A., Herdman, M. T., Stevens, D. L., Jones, N. J., Thacker, J., & Goodhead, D. T. (2004). Relative sensitivities of repair-deficient mammalian cells for clonogenic survival after alpha-particle irradiation.. Radiation research, 162(6), 667-676. doi:10.1667/rr3265DOI: 10.1667/rr3265
Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway. (Journal article)
Qiao, F., Mi, J., Wilson, J. B., Zhi, G., Bucheimer, N. R., Jones, N. J., & Kupfer, G. M. (2004). Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway.. The Journal of biological chemistry, 279(44), 46035-46045. doi:10.1074/jbc.m408323200DOI: 10.1074/jbc.m408323200
FANCG is phosphorylated at serines 383 and 387 during mitosis. (Journal article)
Mi, J., Qiao, F., Wilson, J. B., High, A. A., Schroeder, M. J., Stukenberg, P. T., . . . Kupfer, G. M. (2004). FANCG is phosphorylated at serines 383 and 387 during mitosis.. Molecular and cellular biology, 24(19), 8576-8585. doi:10.1128/mcb.24.19.8576-8585.2004DOI: 10.1128/mcb.24.19.8576-8585.2004
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways (Journal article)
Hussain, S., Wilson, J. B., Medhurst, A. L., Hejna, J., Witt, E., Ananth, S., . . . Mathew, C. G. (2004). Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. HUMAN MOLECULAR GENETICS, 13(12), 1241-1248. doi:10.1093/hmg/ddh135DOI: 10.1093/hmg/ddh135
Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3. (Journal article)
Lamerdin, J. E., Yamada, N. A., George, J. W., Souza, B., Christian, A. T., Jones, N. J., & Thompson, L. H. (2004). Characterization of the hamster FancG/Xrcc9 gene and mutations in CHO UV40 and NM3.. Mutagenesis, 19(3), 237-244. doi:10.1093/mutage/geh019DOI: 10.1093/mutage/geh019
2002
Problems in scoring radiation-induced chromatid breaks (Journal article)
Bryant, P. E., Mozdarani, H., Liu, N., & Jones, N. J. (2002). Problems in scoring radiation-induced chromatid breaks. International Journal of Radiation Biology, 78(10), 947-948.
2001
The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange. (Journal article)
Wilson, J. B., Johnson, M. A., Stuckert, A. P., Trueman, K. L., May, S., Bryant, P. E., . . . Jones, N. J. (2001). The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange.. Carcinogenesis, 22(12), 1939-1946. doi:10.1093/carcin/22.12.1939DOI: 10.1093/carcin/22.12.1939
Phenotype of FAECB (Facility for Automated Experiments in Cell Biology) Chinese hamster ovary mutants with minimal UV-sensitivity. (Journal article)
Busch, D. B., White Ziffer, D., Coleman, D., Wills, L., McDonough, H. G., & Jones, N. J. (2001). Phenotype of FAECB (Facility for Automated Experiments in Cell Biology) Chinese hamster ovary mutants with minimal UV-sensitivity.. Mutation research, 487(1-2), 31-39. doi:10.1016/s0921-8777(01)00099-4DOI: 10.1016/s0921-8777(01)00099-4
The XRCC2 human repair gene influences recombinational rearrangements leading to chromatid breaks. (Journal article)
Mozdarani, H., Liu, N., Jones, N. J., & Bryant, P. E. (2001). The XRCC2 human repair gene influences recombinational rearrangements leading to chromatid breaks.. International journal of radiation biology, 77(8), 859-865. doi:10.1080/09553000110054890DOI: 10.1080/09553000110054890
2000
Isolation of camptothecin-sensitive chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group. (Journal article)
Johnson, M. A., Bryant, P. E., & Jones, N. J. (2000). Isolation of camptothecin-sensitive chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group.. Mutagenesis, 15(4), 367-374. doi:10.1093/mutage/15.4.367DOI: 10.1093/mutage/15.4.367
Biomonitoring the human population exposed to pollution from the oil fires in Kuwait: Analysis of placental tissue using 32P-postlabelling (Journal article)
Marafie, E. M., Marafie, I., Emery, S. J., Waters, R., & Jones, N. J. (2000). Biomonitoring the human population exposed to pollution from the oil fires in Kuwait: Analysis of placental tissue using 32P-postlabelling. Environmental and Molecular Mutagenesis, 36, 274-282.
1999
The isolation and genetic analysis of V79-derived etoposide sensitive Chinese hamster cell mutants; two new complementation groups of etoposide sensitive mutants (Journal article)
Johnson, M. A., & Jones, N. J. (1999). The isolation and genetic analysis of V79-derived etoposide sensitive Chinese hamster cell mutants; two new complementation groups of etoposide sensitive mutants. Mutation Research - DNA Repair, 435, 227-238.
1998
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. (Journal article)
Liu, N., Lamerdin, J. E., Tebbs, R. S., Schild, D., Tucker, J. D., Shen, M. R., . . . Thompson, L. H. (1998). XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages.. Molecular cell, 1(6), 783-793. doi:10.1016/s1097-2765(00)80078-7DOI: 10.1016/s1097-2765(00)80078-7
1997
Comparative induction of micronuclei in repair-deficient and -proficient Chinese hamster cell lines following clastogen or aneugen exposures. (Journal article)
Hermine, T., Jones, N. J., & Parry, J. M. (1997). Comparative induction of micronuclei in repair-deficient and -proficient Chinese hamster cell lines following clastogen or aneugen exposures.. Mutation research, 392(1-2), 151-163. doi:10.1016/s0165-1218(97)00053-0DOI: 10.1016/s0165-1218(97)00053-0
1996
A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity. (Journal article)
Busch, D. B., Zdzienicka, M. Z., Natarajan, A. T., Jones, N. J., Overkamp, W. J., Collins, A., . . . Thompson, L. H. (1996). A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity.. Mutation research, 363(3), 209-221. doi:10.1016/0921-8777(96)00014-6DOI: 10.1016/0921-8777(96)00014-6
Identification of a HeLa mRNA fraction which corrects the mitomycin C sensitivity of irs1 cells (Journal article)
Bender, O., Jones, N. J., Sperling, K., & Digweed, M. (1996). Identification of a HeLa mRNA fraction which corrects the mitomycin C sensitivity of irs1 cells. Mutation Research - DNA Repair, 363, 9-14.
