Photo of Dr Daimark Bennett

Dr Daimark Bennett BSc, DPhil, FHEA

Senior Lecturer Biochemistry

    Publications

    Selected Publications

    1. MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes (Journal article - 2017)
    2. Targeting protein function: the expanding toolkit for conditional disruption (Journal article - 2016)
    3. S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer (Journal article - 2016)
    4. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. (Journal article - 2013)
    5. Lamellipodin and the Scar/WAVE complex cooperate to regulate cell migration in vivo (Journal article - 2013)

    2020

    A method for the permeabilization of live Drosophila melanogaster larvae to small molecules and cryoprotectants. (Journal article)

    Murray, A., Palmer, D., Bennett, D., Dwarampudi, V., & Pedro de Magalhaes, J. (2020). A method for the permeabilization of live Drosophila melanogaster larvae to small molecules and cryoprotectants. FLY. doi:10.1080/19336934.2020.1724051

    DOI: 10.1080/19336934.2020.1724051

    2017

    SERCA directs cell migration and branching across species and germ layers (Journal article)

    Bower, D. V., Lansdale, N., Navarro, S., Truong, T. V., Bower, D. J., Featherstone, N. C., . . . Jesudason, E. C. (2017). SERCA directs cell migration and branching across species and germ layers. BIOLOGY OPEN, 6(10), 1458-1471. doi:10.1242/bio.026039

    DOI: 10.1242/bio.026039

    MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes (Journal article)

    Taylor, E., Alqadri, N., Dodgson, L., Mason, D., Lyulcheva, E., Messina, G., & Bennett, D. H. (2017). MRL proteins cooperate with activated Ras in glia to drive distinct oncogenic outcomes. Oncogene, 36, 4311-4322. doi:10.1038/onc.2017.68

    DOI: 10.1038/onc.2017.68

    Transcriptional responses to hyperplastic MRL signalling in Drosophila. (Journal article)

    Jonchère, V., Alqadri, N., Herbert, J., Dodgson, L., Mason, D., Messina, G., . . . Bennett, D. (2017). Transcriptional responses to hyperplastic MRL signalling in Drosophila.. Open biology, 7(2). doi:10.1098/rsob.160306

    DOI: 10.1098/rsob.160306

    2016

    S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer (Journal article)

    Ismail, T. M., Bennett, D., Platt-Higgins, A. M., Al-Medhity, M., Barraclough, R., & Rudland, P. S. (2017). S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer. CANCER RESEARCH, 77(3), 780-789. doi:10.1158/0008-5472.CAN-16-1802

    DOI: 10.1158/0008-5472.CAN-16-1802

    Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold (Journal article)

    Zacharchenko, T., Barsukov, I., Rigden, D. J., Bennett, D., & Mayans, O. (2016). Biophysical Analysis of the N-Terminal Domain from the Human Protein Phosphatase 1 Nuclear Targeting Subunit PNUTS Suggests an Extended Transcription Factor TFIIS-Like Fold. PROTEIN JOURNAL, 35(5), 340-345. doi:10.1007/s10930-016-9677-7

    DOI: 10.1007/s10930-016-9677-7

    Targeting protein function: the expanding toolkit for conditional disruption (Journal article)

    Campbell, A. E., & Bennett, D. (2016). Targeting protein function: the expanding toolkit for conditional disruption. BIOCHEMICAL JOURNAL, 473, 2573-2589. doi:10.1042/BCJ20160240

    DOI: 10.1042/BCJ20160240

    Targeting protein function: the expanding toolkit for conditional disruption (Journal article)

    Campbell, A. E., & Bennett, D. (2016). Targeting protein function: the expanding toolkit for conditional disruption. Biochemical Journal, 473(17), 2573-2589. doi:10.1042/bcj20160240

    DOI: 10.1042/bcj20160240

    2014

    Drosophila as a Potential Model for Ocular Tumors. (Journal article)

    Bennett, D., Lyulcheva, E., & Cobbe, N. (2015). Drosophila as a Potential Model for Ocular Tumors.. Ocular oncology and pathology, 1(3), 190-199. doi:10.1159/000370155

    DOI: 10.1159/000370155

    2013

    Lamellipodin and the Scar/WAVE complex cooperate to regulate cell migration in vivo (Journal article)

    Law, A. -L., Vehlow, A., Kotini, M., Dodgson, L., Soong, D., Theveneau, E., . . . Krause, M. (2013). Lamellipodin and the Scar/WAVE complex cooperate to regulate cell migration in vivo. Journal of Cell Biology. Retrieved from http://jcb.rupress.org/

    New uses for a familiar technology: introducing mobile phone polling in large classes (Journal article)

    Voelkel, S., & Bennett, D. (2014). New uses for a familiar technology: introducing mobile phone polling in large classes. INNOVATIONS IN EDUCATION AND TEACHING INTERNATIONAL, 51(1), 46-58. doi:10.1080/14703297.2013.770267

    DOI: 10.1080/14703297.2013.770267

    PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. (Journal article)

    Ciurcui, A., Rawling, L., Rudenko, A., Jonchere, V., Lansdale, N., Vasieva, O., . . . Bennett, D. (2013). PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.. PLOS Genetics., 9(10): e1003885.. Retrieved from http://www.plosgenetics.org/

    Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene (Journal article)

    Jonchere, V., & Bennett, D. (n.d.). Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene. PLoS ONE, 8(8), e70489. doi:10.1371/journal.pone.0070489

    DOI: 10.1371/journal.pone.0070489

    2012

    Phenotype and transmission efficiency of artificial and natural male-killing Spiroplasma infections in Drosophila melanogaster (Journal article)

    Hutchence, K. J., Pade, R., Swift, H. L., Bennett, D., & Hurst, G. D. D. (2012). Phenotype and transmission efficiency of artificial and natural male-killing Spiroplasma infections in Drosophila melanogaster. JOURNAL OF INVERTEBRATE PATHOLOGY, 109(2), 243-247. doi:10.1016/j.jip.2011.10.003

    DOI: 10.1016/j.jip.2011.10.003

    2008

    Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability (Journal article)

    Tan, S., Lyulcheva, E., Dean, J., & Bennett, D. (2008). Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability. Journal of Cell Biology, 182(1), 27-33. doi:10.1083/jcb.200712080

    DOI: 10.1083/jcb.200712080

    Drosophila Pico and Its Mammalian Ortholog Lamellipodin Activate Serum Response Factor and Promote Cell Proliferation (Journal article)

    Lyulcheva, E., Taylor, E., Michael, M., Vehlow, A., Tan, S., Fletcher, A., . . . Bennett, D. (2008). Drosophila Pico and Its Mammalian Ortholog Lamellipodin Activate Serum Response Factor and Promote Cell Proliferation. Developmental Cell, 15(5), 680-690. doi:10.1016/j.devcel.2008.09.020

    DOI: 10.1016/j.devcel.2008.09.020

    2007

    Essential, Overlapping and Redundant Roles of the Drosophila Protein Phosphatase 1α and 1β Genes (Journal article)

    Kirchner, J., Gross, S., Bennett, D., & Alphey, L. (2007). Essential, Overlapping and Redundant Roles of the Drosophila Protein Phosphatase 1α and 1β Genes. Genetics, 176(1), 273-281. doi:10.1534/genetics.106.069914

    DOI: 10.1534/genetics.106.069914

    The Nonmuscle Myosin Phosphatase PP1β (flapwing) Negatively Regulates Jun N-Terminal Kinase in Wing Imaginal Discs of Drosophila (Journal article)

    Kirchner, J., Gross, S., Bennett, D., & Alphey, L. (2007). The Nonmuscle Myosin Phosphatase PP1β (flapwing) Negatively Regulates Jun N-Terminal Kinase in Wing Imaginal Discs of Drosophila. Genetics, 175(4), 1741-1749. doi:10.1534/genetics.106.067488

    DOI: 10.1534/genetics.106.067488

    Yeast two-hybrid screens to identify Drosophila PP1-binding proteins (Chapter)

    Bennett, D., & Alphey, L. (2007). Yeast two-hybrid screens to identify Drosophila PP1-binding proteins. In G. Moorhead (Ed.), Methods in Molecular Biology: Protein Phosphatase Protocols (Vol. 365, pp. 155-179). Totowa, United States: Humana Press.

    2006

    The whys and wherefores of phosphate removal (Journal article)

    Bennett, D., Matthews, R. J., & Sathish, J. G. (2006). The whys and wherefores of phosphate removal. EMBO reports, 7(3), 263-268. doi:10.1038/sj.embor.7400644

    DOI: 10.1038/sj.embor.7400644

    Towards a Comprehensive Analysis of the Protein Phosphatase 1 Interactome in Drosophila (Journal article)

    Bennett, D., Lyulcheva, E., & Alphey, L. (2006). Towards a Comprehensive Analysis of the Protein Phosphatase 1 Interactome in Drosophila. Journal of Molecular Biology, 364(2), 196-212. doi:10.1016/j.jmb.2006.08.094

    DOI: 10.1016/j.jmb.2006.08.094

    2005

    Transcriptional control by chromosome-associated protein phosphatase-1 (Journal article)

    Bennett, D. (2005). Transcriptional control by chromosome-associated protein phosphatase-1. Biochemical Society Transactions, 33(6), 1444-1446. doi:10.1042/bst0331444

    DOI: 10.1042/bst0331444

    2004

    Cloning and expression of mars, a novel member of the guanylate kinase associated protein family in Drosophila (Journal article)

    Bennett, D., & Alphey, L. (2004). Cloning and expression of mars, a novel member of the guanylate kinase associated protein family in Drosophila. Gene Expression Patterns, 4(5), 529-535. doi:10.1016/j.modgep.2004.02.006

    DOI: 10.1016/j.modgep.2004.02.006

    PP1?9C interacts with trithorax inDrosophila wing development (Journal article)

    Rudenko, A., Bennett, D., & Alphey, L. (2004). PP1?9C interacts with trithorax inDrosophila wing development. Developmental Dynamics, 231(2), 336-341. doi:10.1002/dvdy.20146

    DOI: 10.1002/dvdy.20146

    The Essential Role of PP1β in Drosophila Is to Regulate Nonmuscle Myosin (Journal article)

    Vereshchagina, N., Bennett, D., Szöőr, B., Kirchner, J., Gross, S., Vissi, E., . . . Alphey, L. (2004). The Essential Role of PP1β in Drosophila Is to Regulate Nonmuscle Myosin. Molecular Biology of the Cell, 15(10), 4395-4405. doi:10.1091/mbc.e04-02-0139

    DOI: 10.1091/mbc.e04-02-0139

    2003

    Ectopic expression of inhibitors of protein phosphatase type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development (Journal article)

    Bennett, D., Szoor, B., Gross, S., Vereshchagina, N., & Alphey, L. (2003). Ectopic expression of inhibitors of protein phosphatase type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development. Genetics, 164(1), 235-245. Retrieved from http://www.genetics.org/cgi/content/abstract/164/1/235

    Trithorax interacts with type 1 serine/threonine protein phosphatase in Drosophila (Journal article)

    Rudenko, A., Bennett, D., & Alphey, L. (2003). Trithorax interacts with type 1 serine/threonine protein phosphatase in Drosophila. EMBO Reports, 4(1), 59-63. doi:10.1038/embor712

    DOI: 10.1038/embor712

    2002

    Functional interaction between nuclear inhibitor of protein phosphatase type 1 (NIPP1) and protein phosphatase type 1 (PP1) in Drosophila: consequences of over-expression of NIPP1 in flies and suppression by co-expression of PP1 (Journal article)

    PARKER, L., GROSS, S., BEULLENS, M., BOLLEN, M., BENNETT, D., & ALPHEY, L. (2002). Functional interaction between nuclear inhibitor of protein phosphatase type 1 (NIPP1) and protein phosphatase type 1 (PP1) in Drosophila: consequences of over-expression of NIPP1 in flies and suppression by co-expression of PP1. Biochemical Journal, 368(3), 789-797. doi:10.1042/bj20020582

    DOI: 10.1042/bj20020582

    PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster (Journal article)

    Bennett, D., & Alphey, L. (2002). PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster. Nature Genetics, 31(4), 419-423. doi:10.1038/ng938

    DOI: 10.1038/ng938