2023
McCormick, L., Wadmore, K., Milburn, A., Gupta, N., Morris, R., Held, M., . . . Helassa, N. (2023). Long QT syndrome-associated calmodulin variants disrupt the activity of the slow delayed rectifier potassium current. JOURNAL OF PHYSIOLOGY-LONDON, 601(17), 3739-3764. doi:10.1113/JP284994DOI: 10.1113/JP284994
Mapping distinct vasodilator-induced phosphorylation patterns in human vascular smooth muscle: A quantitative phosphoproteomic approach (Journal article)
Sloniecka, M., Harris, J., Eyers, C., & Dart, C. (2023). Mapping distinct vasodilator-induced phosphorylation patterns in human vascular smooth muscle: A quantitative phosphoproteomic approach. Physiology, 38(S1). doi:10.1152/physiol.2023.38.s1.5732062DOI: 10.1152/physiol.2023.38.s1.5732062
Prakash, O., Gupta, N., Milburn, A., McCormick, L., Deugi, V., Fisch, P., . . . Helassa, N. (2023). Calmodulin variant E140G associated with long QT syndrome impairs CaMKIIδ autophosphorylation and L-type calcium channel inactivation. JOURNAL OF BIOLOGICAL CHEMISTRY, 299(1). doi:10.1016/j.jbc.2022.102777DOI: 10.1016/j.jbc.2022.102777
Thomas, N. L., Dart, C., & Helassa, N. (2023). Editorial: The role of calcium and calcium binding proteins in cell physiology and disease. FRONTIERS IN PHYSIOLOGY, 14. doi:10.3389/fphys.2023.1228885DOI: 10.3389/fphys.2023.1228885
Manning, D., Barrett-Jolley, R., Evans, R. L., & Dart, C. (2023). TRPC1 channel clustering during store-operated Ca<SUP>2+</SUP> entry in keratinocytes. FRONTIERS IN PHYSIOLOGY, 14. doi:10.3389/fphys.2023.1141006DOI: 10.3389/fphys.2023.1141006
2022
Abrams, S. T. T., Wang, L., Yong, J., Yu, Q., Du, M., Alhamdi, Y., . . . Wang, G. (2022). The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction. BIOMEDICINES, 10(12). doi:10.3390/biomedicines10123256DOI: 10.3390/biomedicines10123256
Manning, D., Dart, C., & Evans, R. L. (2022). Store-operated calcium channels in skin. FRONTIERS IN PHYSIOLOGY, 13. doi:10.3389/fphys.2022.1033528DOI: 10.3389/fphys.2022.1033528
Disease-associated calmodulin mutations disrupt L-type Ca2+channel (Cav1.2) activity and CaMKIIdelta phosphorylation in long QT syndrome (Conference Paper)
Helassa, N., Prakash, O., Gupta, N., McCormick, L. F., Antonyuk, S., & Dart, C. (2022). Disease-associated calmodulin mutations disrupt L-type Ca2+channel (Cav1.2) activity and CaMKIIdelta phosphorylation in long QT syndrome. In EUROPEAN HEART JOURNAL Vol. 43 (pp. 2982). Retrieved from https://www.webofscience.com/
Long QT syndrome-associated calmodulin mutations and their interactions with the Kv7.1 voltage-gated potassium channel (Journal article)
McCormick, L. F., Gupta, N., Prakash, O., Lian, L. Y., Dart, C., & Helassa, N. (2022). Long QT syndrome-associated calmodulin mutations and their interactions with the Kv7.1 voltage-gated potassium channel. European Heart Journal, 43(Supplement_2). doi:10.1093/eurheartj/ehac544.2983DOI: 10.1093/eurheartj/ehac544.2983
Long QT Syndrome-Associated Mutations D130V and E141K Affect the Structure-Function Relationship of Calmodulin (Conference Paper)
Wadmore, K., Dart, C., & Helassa, N. (2022). Long QT Syndrome-Associated Mutations D130V and E141K Affect the Structure-Function Relationship of Calmodulin. In ACTA PHYSIOLOGICA Vol. 236 (pp. 586-587). Retrieved from https://www.webofscience.com/
CALMODULIN MUTATIONS ASSOCIATED WITH LONG QT SYNDROME IMPAIR L-TYPE CALCIUM CHANNEL REGULATION (Conference Paper)
Gupta, N., McCormick, L. F., Prakash, O., Lian, L. -Y., Dart, C., & Helassa, N. (2022). CALMODULIN MUTATIONS ASSOCIATED WITH LONG QT SYNDROME IMPAIR L-TYPE CALCIUM CHANNEL REGULATION. In HEART Vol. 108 (pp. A150-A151). doi:10.1136/heartjnl-2022-BCS.192DOI: 10.1136/heartjnl-2022-BCS.192
LONG QT SYNDROME-ASSOCIATED CALMODULIN MUTATIONS AFFECT INTERACTION WITH L-TYPE CA2+CHANNEL (CAV1.2) AND CAMKIIΔ ACTIVITY (Conference Paper)
Prakash, O., Gupta, N., McCormick, L. F., Antonyuk, S., Dart, C., & Helassa, N. (2022). LONG QT SYNDROME-ASSOCIATED CALMODULIN MUTATIONS AFFECT INTERACTION WITH L-TYPE CA2+CHANNEL (CAV1.2) AND CAMKIIΔ ACTIVITY. In HEART Vol. 108 (pp. A148). doi:10.1136/heartjnl-2022-BCS.189DOI: 10.1136/heartjnl-2022-BCS.189
LONG QT SYNDROME-ASSOCIATED CALMODULIN MUTATIONS DISRUPT KV7.1 VOLTAGE-GATED POTASSIUM CHANNEL FUNCTION (Conference Paper)
McCormick, L. F., Gupta, N., Prakash, O., Lian, L. -Y., Dart, C., & Helassa, N. (2022). LONG QT SYNDROME-ASSOCIATED CALMODULIN MUTATIONS DISRUPT KV7.1 VOLTAGE-GATED POTASSIUM CHANNEL FUNCTION. In HEART Vol. 108 (pp. A149). doi:10.1136/heartjnl-2022-BCS.190DOI: 10.1136/heartjnl-2022-BCS.190
McCormick, L. (2022, March 28). Long QT Syndrome-Associated Calmodulin Mutations and Their Interactions with the Kv7.1 Voltage-Gated Potassium Channel.
2020
Yang, M., Dart, C., Kamishima, T., & Quayle, J. M. (2020). Hypoxia and metabolic inhibitors alter the intracellular ATP:ADP ratio and membrane potential in human coronary artery smooth muscle cells.. PeerJ, 8, e10344. doi:10.7717/peerj.10344DOI: 10.7717/peerj.10344
Calcium Store-Operated Currents in Human Skin Cells (Conference Paper)
Manning, D., Evans, R. L., & Dart, C. (2020). Calcium Store-Operated Currents in Human Skin Cells. In BIOPHYSICAL JOURNAL Vol. 118 (pp. 563A). Retrieved from https://www.webofscience.com/
LQTS-Associated Mutants of Calmodulin Show Disrupted Interaction with L-Type Calcium Channels (Conference Paper)
Gupta, N., McCormick, L. F., Haynes, L. P., Dart, C., & Helassa, N. (2020). LQTS-Associated Mutants of Calmodulin Show Disrupted Interaction with L-Type Calcium Channels. In BIOPHYSICAL JOURNAL Vol. 118 (pp. 405A). Retrieved from https://www.webofscience.com/
Long-QT Syndrome-Associated Calmodulin Mutations and Their Interactions at the K<sub>v</sub>7.1 Potassium Channel (Conference Paper)
McCormick, L. F., Gupta, N., Haynes, L. P., Antonyuk, S., Dart, C., & Helassa, N. (2020). Long-QT Syndrome-Associated Calmodulin Mutations and Their Interactions at the K<sub>v</sub>7.1 Potassium Channel. In BIOPHYSICAL JOURNAL Vol. 118 (pp. 404A). Retrieved from https://www.webofscience.com/
Celik, N., O’Brien, F., Brennan, S., Rainbow, R. D., Dart, C., Zheng, Y., . . . Barrett-Jolley, R. (2020). Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data. Communications Biology, 3, 1-10. doi:10.1038/s42003-019-0729-3DOI: 10.1038/s42003-019-0729-3
2019
Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data (Journal article)
Celik, N., O’Brien, F., Brennan, S., Rainbow, R., Dart, C., Zheng, Y., . . . Barrett-Jolley, R. (n.d.). Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data. BioRxiv. doi:10.1101/767418DOI: 10.1101/767418
Soluble adenylyl cyclase links Ca2+ entry to Ca2+/cAMP-response element binding protein (CREB) activation in vascular smooth muscle (Journal article)
Parker, T., Wang, K. -W., Manning, D., & Dart, C. (2019). Soluble adenylyl cyclase links Ca2+ entry to Ca2+/cAMP-response element binding protein (CREB) activation in vascular smooth muscle. Scientific Reports, 9. doi:10.1038/s41598-019-43821-3DOI: 10.1038/s41598-019-43821-3
2017
Humphries, E. S. A., Kamishima, T., Quayle, J. M., & Dart, C. (2017). Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle. The Journal of Physiology, 595(18), 6147-6164. doi:10.1113/JP274754DOI: 10.1113/JP274754
Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention (Journal article)
Yang, M., Chadwick, A., Dart, C., Kamishima, T., & Quayle, J. (2017). Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention. PLoS One, 12(5). doi:10.1371/journal.pone.0177951DOI: 10.1371/journal.pone.0177951
2016
Activation of calcium/calmodulin-dependent kinase 2 (CaMKII) mediates Epac-induced increases in spontaneous transient outward current in rat mesenteric artery smooth muscle (Conference Paper)
Humphries, E. S. A., Kamishima, T., Quayle, J. M., & Dart, C. (2016). Activation of calcium/calmodulin-dependent kinase 2 (CaMKII) mediates Epac-induced increases in spontaneous transient outward current in rat mesenteric artery smooth muscle. In Proceedings of the Physiological Society Vol. PCB313. Dublin, Ireland.
Dart, C., & Humphries, E. S. A. (2016). Epac-mediated Vasorelaxation: Epac Increases Spontaneous Transient Outward Current (STOC) In Mesenteric Artery Smooth Muscle Via Activation Of CAMKII. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/
Epac‐mediated Vasorelaxation: Epac Increases Spontaneous Transient Outward Current (STOC) In Mesenteric Artery Smooth Muscle Via Activation Of CAMKII (Journal article)
Dart, C., & Humphries, E. S. A. (2016). Epac‐mediated Vasorelaxation: Epac Increases Spontaneous Transient Outward Current (STOC) In Mesenteric Artery Smooth Muscle Via Activation Of CAMKII. The FASEB Journal, 30(S1). doi:10.1096/fasebj.30.1_supplement.969.24DOI: 10.1096/fasebj.30.1_supplement.969.24
2015
Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls (Journal article)
Humphries, E. S. A., & Dart, C. (2015). Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls. JOURNAL OF BIOMOLECULAR SCREENING, 20(9), 1055-1073. doi:10.1177/1087057115601677DOI: 10.1177/1087057115601677
Oxygen regulation of human coronary artery smooth muscle cell proliferation and migration (Conference Paper)
Yang, M. M., Kamishima, T., Dart, C., & Quayle, J. M. (2015). Oxygen regulation of human coronary artery smooth muscle cell proliferation and migration. In Arteriosclerosis, Thrombosis, and Vascular Biology Vol. 35. San Francisco.
The effects of hypoxia and metabolic inhibitors on cellular ATP and ATP/ADP ratio in human coronary artery smooth muscle cells (Conference Paper)
Yang, M. M., Kamishima, T., Roberts, O. L. L., Dart, C., & Quayle, J. M. (2015). The effects of hypoxia and metabolic inhibitors on cellular ATP and ATP/ADP ratio in human coronary artery smooth muscle cells. In Arteriosclerosis Thrombosis and Vascular Biology Vol. 35. San Francisco: Lippincott Williams & Wilkins Ltd..
Abstract 451: Oxygen Regulation of Human Coronary Artery Smooth Muscle Cell Proliferation and Migration (Journal article)
Yang, M., Kamishima, T., Dart, C., & Quayle, J. M. (2015). Abstract 451: Oxygen Regulation of Human Coronary Artery Smooth Muscle Cell Proliferation and Migration. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(suppl_1). doi:10.1161/atvb.35.suppl_1.451DOI: 10.1161/atvb.35.suppl_1.451
Feetham, C., Nunn, N., Lewis, R., Dart, C., & Barrett-Jolley, R. (2015). TRPV4 and KCa functionally couple as osmosensors in the PVN. British Journal of Pharmacology, 172(7), 1753-1768. doi:10.1111/bph.13023DOI: 10.1111/bph.13023
Al-Brakati, A. Y., Kamishima, T., Dart, C., & Quayle, J. M. (2015). Caveolar disruption causes contraction of rat femoral arteries via reduced basal NO release and subsequent closure of BK<sub>Ca</sub> channels. PEERJ, 3. doi:10.7717/peerj.966DOI: 10.7717/peerj.966
2014
cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP) (Journal article)
Roberts, O. L., & Dart, C. (2014). cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP). BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 89-97. doi:10.1042/BST20130253DOI: 10.1042/BST20130253
Caveolae as specialized lipid rafts: Diverse roles in the regulation of potassium channel signalling (Chapter)
Byrne, D., & Dart, C. (2014). Caveolae as specialized lipid rafts: Diverse roles in the regulation of potassium channel signalling. In Lipid Rafts: Properties, Controversies and Roles in Signal Transduction (pp. 53-68).
Verdict in the Smooth Muscle K<sub>ATP</sub> Channel Case Guilty of Blood Pressure Control But Innocent of Sudden Death Phenotype (Journal article)
Dart, C. (2014). Verdict in the Smooth Muscle K<sub>ATP</sub> Channel Case Guilty of Blood Pressure Control But Innocent of Sudden Death Phenotype. HYPERTENSION, 64(3), 457-458. doi:10.1161/HYPERTENSIONAHA.114.03289DOI: 10.1161/HYPERTENSIONAHA.114.03289
2013
Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca<SUP>2+</SUP>-sensitive K<SUP>+</SUP> channels in rat mesenteric artery (Journal article)
Roberts, O. L., Kamishima, T., Barrett-Jolley, R., Quayle, J. M., & Dart, C. (2013). Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca<SUP>2+</SUP>-sensitive K<SUP>+</SUP> channels in rat mesenteric artery. JOURNAL OF PHYSIOLOGY-LONDON, 591(20), 5107-5123. doi:10.1113/jphysiol.2013.262006DOI: 10.1113/jphysiol.2013.262006
Human CRP Defends against the Toxicity of Circulating Histones (Journal article)
Abrams, S. T., Zhang, N., Dart, C., Wang, S. S., Thachil, J., Guan, Y., . . . Toh, C. -H. (2013). Human CRP Defends against the Toxicity of Circulating Histones. JOURNAL OF IMMUNOLOGY, 191(5), 2495-2502. doi:10.4049/jimmunol.1203181DOI: 10.4049/jimmunol.1203181
Effect of the Epac activator 8-pCPT-2′-O-Me-cAMP (8-pCPT) on the expression pattern of VE-cadherin (VE-cad) & connexins (Cxs) in Human Coronary Artery Endothelial Cells (HCAECs) (Conference Paper)
Quinn, R. E., Roberts, O., Kamishima, T., Dart, C., & Quayle, J. (2013). Effect of the Epac activator 8-pCPT-2′-O-Me-cAMP (8-pCPT) on the expression pattern of VE-cadherin (VE-cad) & connexins (Cxs) in Human Coronary Artery Endothelial Cells (HCAECs). In FASEB JOURNAL Vol. 27. Retrieved from https://www.webofscience.com/
Abrams, S. T., Zhang, N., Manson, J., Liu, T., Dart, C., Baluwa, F., . . . Toh, C. -H. (2013). Circulating Histones Are Mediators of Trauma-associated Lung Injury. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187(2), 160-169. doi:10.1164/rccm.201206-1037OCDOI: 10.1164/rccm.201206-1037OC
Selective Activation of Epac Increases the Frequency of Submembrane Calcium Sparks in Mesenteric Smooth Muscle Cells (Conference Paper)
Roberts, O. L., Kamishima, T., Barrett-Jolley, R., Quayle, J. M., & Dart, C. (2013). Selective Activation of Epac Increases the Frequency of Submembrane Calcium Sparks in Mesenteric Smooth Muscle Cells. In BIOPHYSICAL JOURNAL Vol. 104 (pp. 614A-615A). Retrieved from https://www.webofscience.com/
Structural diversity of the cAMP-dependent protein kinase regulatory subunit in <i>Caenorhabditis elegans</i> (Journal article)
Pastok, M. W., Prescott, M. C., Dart, C., Murray, P., Rees, H. H., & Fisher, M. J. (2013). Structural diversity of the cAMP-dependent protein kinase regulatory subunit in <i>Caenorhabditis elegans</i>. CELLULAR SIGNALLING, 25(1), 168-177. doi:10.1016/j.cellsig.2012.09.006DOI: 10.1016/j.cellsig.2012.09.006
2012
Potassium channels in articular chondrocytes (Journal article)
Mobasheri, A., Lewis, R., Ferreira-Mendes, A., Rufino, A., Dart, C., & Barrett-Jolley, R. (2012). Potassium channels in articular chondrocytes. CHANNELS, 6(6), 416-425. doi:10.4161/chan.22340DOI: 10.4161/chan.22340
Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif? (Journal article)
Byrne, D. P., Dart, C., & Rigden, D. J. (2012). Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?. PLOS ONE, 7(9). doi:10.1371/journal.pone.0044879DOI: 10.1371/journal.pone.0044879
Selective block of KATP channels: why the anti-diabetic sulphonylureas and rosiglitazone have more in common than we thought (Journal article)
Dart, C. (2012). Selective block of KATP channels: why the anti-diabetic sulphonylureas and rosiglitazone have more in common than we thought. BRITISH JOURNAL OF PHARMACOLOGY, 167(1), 23-25. doi:10.1111/j.1476-5381.2012.01990.xDOI: 10.1111/j.1476-5381.2012.01990.x
Indirect Channel Regulation by Cholesterol: The Role of Caveolae and Caveolins in Regulating K
<sub>ATP</sub>
Channel Function (Chapter)
Dart, C. (2012). Indirect Channel Regulation by Cholesterol: The Role of Caveolae and Caveolins in Regulating K <sub>ATP</sub> Channel Function. In Unknown Book (pp. 161-179). Wiley. doi:10.1002/9781118342312.ch8DOI: 10.1002/9781118342312.ch8
2011
The Role of the Membrane Potential in Chondrocyte Volume Regulation (Journal article)
Lewis, R., Asplin, K. E., Bruce, G., Dart, C., Mobasheri, A., & Barrett-Jolley, R. (2011). The Role of the Membrane Potential in Chondrocyte Volume Regulation. JOURNAL OF CELLULAR PHYSIOLOGY, 226(11), 2979-2986. doi:10.1002/jcp.22646DOI: 10.1002/jcp.22646
Function and Pharmacology of Spinally-Projecting Sympathetic Pre-Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus (Journal article)
Nunn, N., Womack, M., Dart, C., & Barrett-Jolley, R. (2011). Function and Pharmacology of Spinally-Projecting Sympathetic Pre-Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus. CURRENT NEUROPHARMACOLOGY, 9(2), 262-277. Retrieved from https://www.webofscience.com/
Function and Pharmacology of Spinally-Projecting Sympathetic Pre- Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus (Journal article)
Nunn, N., Womack, M., Dart, C., & Barrett-Jolley, R. (2011). Function and Pharmacology of Spinally-Projecting Sympathetic Pre- Autonomic Neurones in the Paraventricular Nucleus of the Hypothalamus. Current Neuropharmacology, 999(999), 1-16. doi:10.2174/157021107012043159xDOI: 10.2174/157021107012043159x
2010
Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (K<sub>ATP</sub>) channel activity (Journal article)
Davies, L. M., Purves, G. I., Barrett-Jolley, R., & Dart, C. (2010). Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (K<sub>ATP</sub>) channel activity. JOURNAL OF PHYSIOLOGY-LONDON, 588(17), 3254-3265. doi:10.1113/jphysiol.2010.194779DOI: 10.1113/jphysiol.2010.194779
Lipid microdomains and the regulation of ion channel function (Journal article)
Dart, C. (2010). Lipid microdomains and the regulation of ion channel function. JOURNAL OF PHYSIOLOGY-LONDON, 588(17), 3169-3178. doi:10.1113/jphysiol.2010.191585DOI: 10.1113/jphysiol.2010.191585
Caveolin-1 Inhibits Vascular K<sub>ATP</sub> Channels by Modulating Channel Sensitivity to MgADP (Conference Paper)
Davies, L. M., Purves, G. I., Barrett-Jolley, R., & Dart, C. (2010). Caveolin-1 Inhibits Vascular K<sub>ATP</sub> Channels by Modulating Channel Sensitivity to MgADP. In BIOPHYSICAL JOURNAL Vol. 98 (pp. 698A). doi:10.1016/j.bpj.2009.12.3830DOI: 10.1016/j.bpj.2009.12.3830
Epac-Mediated Mobilization of Intracellular Calcium in Vascular Myocytes and the Downstream Effects on Arterial K<sub>ATP</sub> Channels (Conference Paper)
Purves, G. I., Kamishima, T., Davies, L. M., Quayle, J. M., & Dart, C. (2010). Epac-Mediated Mobilization of Intracellular Calcium in Vascular Myocytes and the Downstream Effects on Arterial K<sub>ATP</sub> Channels. In BIOPHYSICAL JOURNAL Vol. 98 (pp. 138A). doi:10.1016/j.bpj.2009.12.743DOI: 10.1016/j.bpj.2009.12.743
2009
Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels (Journal article)
Purves, G. I., Kamishima, T., Davies, L. M., Quayle, J. M., & Dart, C. (2009). Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels. JOURNAL OF PHYSIOLOGY-LONDON, 587(14), 3639-3650. doi:10.1113/jphysiol.2009.173534DOI: 10.1113/jphysiol.2009.173534
2008
Lipid microdomains and k(+) channel compartmentation: detergent and non-detergent-based methods for the isolation and characterisation of cholesterol-enriched lipid rafts. (Journal article)
Sampson, L. J., & Dart, C. (2008). Lipid microdomains and k(+) channel compartmentation: detergent and non-detergent-based methods for the isolation and characterisation of cholesterol-enriched lipid rafts.. Methods in molecular biology (Clifton, N.J.), 491, 91-101. doi:10.1007/978-1-59745-526-8_7DOI: 10.1007/978-1-59745-526-8_7
Potassium Ion Channels in Articular Chondrocytes (Chapter)
Mobasheri, A., Dart, C., & Barrett-Jolley, R. (n.d.). Potassium Ion Channels in Articular Chondrocytes. In Mechanosensitivity in Cells and Tissues (pp. 157-178). Springer Netherlands. doi:10.1007/978-1-4020-6426-5_7DOI: 10.1007/978-1-4020-6426-5_7
2007
Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1 (Journal article)
Goult, B. T., Rapley, J. D., Dart, C., Kitmitto, A., Grossmann, J. G., Leyland, M. L., & Lian, L. -Y. (2007). Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1. BIOCHEMISTRY, 46(49), 14117-14128. doi:10.1021/bi701257zDOI: 10.1021/bi701257z
Angiotensin II-activated protein kinase C targets caveolae to inhibit aortic ATP-sensitive potassium channels (Journal article)
Sampson, L. J., Davies, L. M., Barrett-Jolley, R., Standen, N. B., & Dart, C. (2007). Angiotensin II-activated protein kinase C targets caveolae to inhibit aortic ATP-sensitive potassium channels. CARDIOVASCULAR RESEARCH, 76(1), 61-70. doi:10.1016/j.cardiores.2007.05.020DOI: 10.1016/j.cardiores.2007.05.020
Vasoconstrictor-induced targeting of PKC lsozymes to smooth muscle caveolae (Conference Paper)
Sampson, L. J., Standen, N. B., & Dart, C. (2007). Vasoconstrictor-induced targeting of PKC lsozymes to smooth muscle caveolae. In BIOPHYSICAL JOURNAL (pp. 131A). Retrieved from https://www.webofscience.com/
2005
The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death (Journal article)
Cao, J., Viholainen, J. I., Dart, C., Warwick, H. K., Leyland, M. L., & Courtney, M. J. (2005). The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. JOURNAL OF CELL BIOLOGY, 168(1), 117-126. doi:10.1083/jcb.200407024DOI: 10.1083/jcb.200407024
Activated protein kinase C epsilon localises to smooth muscle caveolae (Conference Paper)
Sampson, L. J., Davis, A. J., Standen, N. B., & Dart, C. (2005). Activated protein kinase C epsilon localises to smooth muscle caveolae. In BIOPHYSICAL JOURNAL Vol. 88 (pp. 626A). Retrieved from https://www.webofscience.com/
Identification of a binding site for the kinase-anchoring protein, AKAP79 on the inwardly rectifying potassium channel, Kir2.1. (Conference Paper)
Davis, A. J., & Dart, C. (2005). Identification of a binding site for the kinase-anchoring protein, AKAP79 on the inwardly rectifying potassium channel, Kir2.1.. In BIOPHYSICAL JOURNAL Vol. 88 (pp. 106A). Retrieved from https://www.webofscience.com/
2004
Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels (Journal article)
Sampson, L. J., Hayabuchi, Y., Standen, N. B., & Dart, C. (2004). Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels. CIRCULATION RESEARCH, 95(10), 1012-1018. doi:10.1161/01.RES.0000148634.47095.abDOI: 10.1161/01.RES.0000148634.47095.ab
An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1 (Journal article)
Leyland, M. L., & Dart, C. (2004). An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(42), 43427-43436. doi:10.1074/jbc.M407575200DOI: 10.1074/jbc.M407575200
2003
Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1 (Journal article)
Sampson, L. J., Leyland, M. L., & Dart, C. (2003). Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(43), 41988-41997. doi:10.1074/jbc.M307479200DOI: 10.1074/jbc.M307479200
Binding of a novel alternatively spliced isoform of PSD-93 to the inwardly rectiftying potassium channel Kir2.1 (Journal article)
Leyland, M. L., & Dart, C. (2003). Binding of a novel alternatively spliced isoform of PSD-93 to the inwardly rectiftying potassium channel Kir2.1. BIOPHYSICAL JOURNAL, 84(2), 223A. Retrieved from https://www.webofscience.com/
Identification of filamin-A as an interacting partner of inwardly rectifying potassium channel, Kir2.1 (Journal article)
Sampson, L. J., Dart, C., & Leyland, M. L. (2003). Identification of filamin-A as an interacting partner of inwardly rectifying potassium channel, Kir2.1. BIOPHYSICAL JOURNAL, 84(2), 223A. Retrieved from https://www.webofscience.com/
2002
Effects of cortisol on neuronal excitability (Journal article)
Zaki, A., Dart, C., & Barrett-Jolley, R. (2002). Effects of cortisol on neuronal excitability. BIOPHYSICAL JOURNAL, 82(1), 626A. Retrieved from https://www.webofscience.com/
Interaction between inwardly rectifying potassium channel, Kir 2.1, and synapse-associated protein-97 in the porcine coronary artery (Journal article)
Sampson, L. J., Dart, C., & Leyland, M. L. (2002). Interaction between inwardly rectifying potassium channel, Kir 2.1, and synapse-associated protein-97 in the porcine coronary artery. JOURNAL OF PHYSIOLOGY-LONDON, 544, 25P. Retrieved from https://www.webofscience.com/
2001
Evidence for involvement of A-kinase anchoring protein in activation of rat arterial K<sub>ATP</sub> channels by protein kinase A (Journal article)
Hayabuchi, Y., Dart, C., & Standen, N. B. (2001). Evidence for involvement of A-kinase anchoring protein in activation of rat arterial K<sub>ATP</sub> channels by protein kinase A. JOURNAL OF PHYSIOLOGY-LONDON, 536(2), 421-427. doi:10.1111/j.1469-7793.2001.0421c.xdDOI: 10.1111/j.1469-7793.2001.0421c.xd
Evidence for involvement of A-kinase anchoring protein in activation of rat arterial K(ATP) channels by protein kinase A. (Journal article)
Hayabuchi, Y., Dart, C., & Standen, N. B. (2001). Evidence for involvement of A-kinase anchoring protein in activation of rat arterial K(ATP) channels by protein kinase A.. J Physiol, 536(Pt 2), 421-427. doi:10.1111/j.1469-7793.2001.0421c.xdDOI: 10.1111/j.1469-7793.2001.0421c.xd
Targeting of an a kinase-anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1 (Journal article)
Dart, C., & Leyland, M. L. (2001). Targeting of an a kinase-anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(23), 20499-20505. doi:10.1074/jbc.M101425200DOI: 10.1074/jbc.M101425200
Targeting of an A-kinase anchoring protein, AKAP79, to an inwardly rectifying potassium channel, murine Kir2.1 (Journal article)
Dart, C., & Leyland, M. L. (2001). Targeting of an A-kinase anchoring protein, AKAP79, to an inwardly rectifying potassium channel, murine Kir2.1. JOURNAL OF PHYSIOLOGY-LONDON, 533, 112P. Retrieved from https://www.webofscience.com/
2000
Modelling the block of IRK1 channels by silver ions. (Conference Paper)
Barrett-Jolley, R., & Dart, C. (2000). Modelling the block of IRK1 channels by silver ions.. In BIOPHYSICAL JOURNAL Vol. 78 (pp. 350A). Retrieved from https://www.webofscience.com/
Studies of structure and function in inward rectifier potassium channels (Journal article)
Abrams, C. J., Ashmole, I., Brammar, W. J., Conley, E. C., Dart, C., Davies, N. W., . . . Stanfield, P. R. (2000). Studies of structure and function in inward rectifier potassium channels. JOURNAL OF PHYSIOLOGY-LONDON, 523, 4S-5S. Retrieved from https://www.webofscience.com/
1999
Direct block of native and cloned (Kir2.1) inward rectifier K<SUP>+</SUP> channels by chloroethylclonidine (Journal article)
Barrett-Jolley, R., Dart, C., & Standen, N. B. (1999). Direct block of native and cloned (Kir2.1) inward rectifier K<SUP>+</SUP> channels by chloroethylclonidine. BRITISH JOURNAL OF PHARMACOLOGY, 128(3), 760-766. doi:10.1038/sj.bjp.0702819DOI: 10.1038/sj.bjp.0702819
The possible role of a disulphide bond in forming functional Kir2.1 potassium channels (Journal article)
Leyland, M. L., Dart, C., Spencer, P. J., Sutcliffe, M. J., & Stanfield, P. R. (1999). The possible role of a disulphide bond in forming functional Kir2.1 potassium channels. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 438(6), 778-781. doi:10.1007/s004240051106DOI: 10.1007/s004240051106
Topology of the pore region of an inward rectifier K<SUP>+</SUP> channel, Kir2.1 (Conference Paper)
Dart, C., Leyland, M. L., Spencer, P. J., Stanfield, P. R., & Sutcliffe, M. J. (1999). Topology of the pore region of an inward rectifier K<SUP>+</SUP> channel, Kir2.1. In MOLECULAR AND FUNCTIONAL DIVERSITY OF ION CHANNELS AND RECEPTORS Vol. 868 (pp. 414-417). doi:10.1111/j.1749-6632.1999.tb11303.xDOI: 10.1111/j.1749-6632.1999.tb11303.x
1998
The dependence of Ag<SUP>+</SUP> block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter (Journal article)
Dart, C., Leyland, M. L., Barrett-Jolley, R., Shelton, P. A., Spencer, P. J., Conley, E. C., . . . Stanfield, P. R. (1998). The dependence of Ag<SUP>+</SUP> block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter. JOURNAL OF PHYSIOLOGY-LONDON, 511(1), 15-24. doi:10.1111/j.1469-7793.1998.015bi.xDOI: 10.1111/j.1469-7793.1998.015bi.x
The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis (Journal article)
Dart, C., Leyland, M. L., Spencer, P. J., Stanfield, P. R., & Sutcliffe, M. J. (1998). The selectivity filter of a potassium channel, murine Kir2.1, investigated using scanning cysteine mutagenesis. JOURNAL OF PHYSIOLOGY-LONDON, 511(1), 25-32. doi:10.1111/j.1469-7793.1998.025bi.xDOI: 10.1111/j.1469-7793.1998.025bi.x
1997
Block of inward rectifier IRK1 by sulfhydryl-specific reagents (Conference Paper)
Dart, C., Leyland, M. L., BarrettJolley, R., & Stanfield, P. R. (1997). Block of inward rectifier IRK1 by sulfhydryl-specific reagents. In BIOPHYSICAL JOURNAL Vol. 72 (pp. WPO33). Retrieved from https://www.webofscience.com/
Possible topology of the H5 region of an inward rectifier K+ channel, murine IRK1. (Journal article)
Dart, C., Leyland, M. L., Spencer, P. J., Conley, E. C., Stanfield, P. R., & Sutcliffe, M. J. (1997). Possible topology of the H5 region of an inward rectifier K+ channel, murine IRK1.. JOURNAL OF PHYSIOLOGY-LONDON, 504P, P155. Retrieved from https://www.webofscience.com/
Single subunit mutations of the murine K+ channel IRK1 (Journal article)
Leyland, M. L., Shelton, P. A., Dart, C., Conley, E. C., & Stanfield, P. R. (1997). Single subunit mutations of the murine K+ channel IRK1. JOURNAL OF PHYSIOLOGY-LONDON, 499P, P125-P126. Retrieved from https://www.webofscience.com/
1996
THE ROLE OF POTASSIUM CHANNELS IN T LYMPHOCYTES (Journal article)
Badley, S., Dart, C., Conley, E., & Brammar, W. (1996). THE ROLE OF POTASSIUM CHANNELS IN T LYMPHOCYTES. Biochemical Society Transactions, 24(4), 509S. doi:10.1042/bst024509scDOI: 10.1042/bst024509sc
The use of the rat LAP LCR and promoter for the high-level constitutive expression of K+ channel cDNAs in a rat liver cell line (Journal article)
Shelton, P. A., & Dart, C. (1996). The use of the rat LAP LCR and promoter for the high-level constitutive expression of K+ channel cDNAs in a rat liver cell line. FEBS LETTERS, 391(3), 282-286. doi:10.1016/0014-5793(96)00755-7DOI: 10.1016/0014-5793(96)00755-7
The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle (Journal article)
Quayle, J. M., Dart, C., & Standen, N. B. (1996). The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle. JOURNAL OF PHYSIOLOGY-LONDON, 494(3), 715-726. doi:10.1113/jphysiol.1996.sp021527DOI: 10.1113/jphysiol.1996.sp021527
1995
ACTIVATION OF ATP-DEPENDENT K+ CHANNELS BY HYPOXIA IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PIG CORONARY-ARTERY (Journal article)
DART, C., & STANDEN, N. B. (1995). ACTIVATION OF ATP-DEPENDENT K+ CHANNELS BY HYPOXIA IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PIG CORONARY-ARTERY. JOURNAL OF PHYSIOLOGY-LONDON, 483(1), 29-39. doi:10.1113/jphysiol.1995.sp020565DOI: 10.1113/jphysiol.1995.sp020565
1994
Adenosine activates potassium channels in porcine coronary arterial myocytes (Conference Paper)
DART, C., & STANDEN, N. B. (1994). Adenosine activates potassium channels in porcine coronary arterial myocytes. In RESISTANCE ARTERIES (pp. 115-123). Retrieved from https://www.webofscience.com/
HYPOXIA INDUCES A POTASSIUM CURRENT IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PORCINE CORONARY-ARTERY (Journal article)
DART, C., & STANDEN, N. B. (1994). HYPOXIA INDUCES A POTASSIUM CURRENT IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PORCINE CORONARY-ARTERY. JOURNAL OF PHYSIOLOGY-LONDON, 477P, P85-P86. Retrieved from https://www.webofscience.com/
1993
ADENOSINE-ACTIVATED POTASSIUM CURRENT IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PIG CORONARY-ARTERY (Journal article)
DART, C., & STANDEN, N. B. (1993). ADENOSINE-ACTIVATED POTASSIUM CURRENT IN SMOOTH-MUSCLE CELLS ISOLATED FROM THE PIG CORONARY-ARTERY. JOURNAL OF PHYSIOLOGY-LONDON, 471, 767-786. doi:10.1113/jphysiol.1993.sp019927DOI: 10.1113/jphysiol.1993.sp019927
THE POTASSIUM CURRENT ACTIVATED BY ADENOSINE IN ISOLATED CORONARY ARTERIAL MYOCYTES OF THE PIG (Journal article)
DART, C., & STANDEN, N. B. (1993). THE POTASSIUM CURRENT ACTIVATED BY ADENOSINE IN ISOLATED CORONARY ARTERIAL MYOCYTES OF THE PIG. JOURNAL OF PHYSIOLOGY-LONDON, 467, P270. Retrieved from https://www.webofscience.com/
WHOLE CELL K+ CURRENT ACTIVATED BY LEMAKALIM IN ISOLATED MYOCYTES FROM RABBIT PULMONARY-ARTERY - ESTIMATE OF UNITARY CONDUCTANCE AND DENSITY BY NOISE-ANALYSIS (Journal article)
LANGTON, P. D., CLAPP, L. H., DART, C., GURNEY, A. M., & STANDEN, N. B. (1993). WHOLE CELL K+ CURRENT ACTIVATED BY LEMAKALIM IN ISOLATED MYOCYTES FROM RABBIT PULMONARY-ARTERY - ESTIMATE OF UNITARY CONDUCTANCE AND DENSITY BY NOISE-ANALYSIS. JOURNAL OF PHYSIOLOGY-LONDON, 459, P254. Retrieved from https://www.webofscience.com/
1992
NA(+)-HCO3- SYMPORT IN THE SHEEP CARDIAC PURKINJE-FIBER (Journal article)
DART, C., & VAUGHANJONES, R. D. (1992). NA(+)-HCO3- SYMPORT IN THE SHEEP CARDIAC PURKINJE-FIBER. JOURNAL OF PHYSIOLOGY-LONDON, 451, 365-385. doi:10.1113/jphysiol.1992.sp019169DOI: 10.1113/jphysiol.1992.sp019169
EVIDENCE FOR A NA+-CL--H+-HCO3- EXCHANGE SYSTEM IN THE MAMMALIAN LENS (Journal article)
DUNCAN, G., DART, C., CROGHAN, P. C., & GANDOLFI, S. A. (1992). EVIDENCE FOR A NA+-CL--H+-HCO3- EXCHANGE SYSTEM IN THE MAMMALIAN LENS. EXPERIMENTAL EYE RESEARCH, 54(6), 941-946. doi:10.1016/0014-4835(92)90158-ODOI: 10.1016/0014-4835(92)90158-O
1990
A HCO3-DEPENDENT MECHANISM REGULATES PHI FROM AN ACID LOAD IN ISOLATED SHEEP CARDIAC PURKINJE-FIBERS (Conference Paper)
DART, C., & VAUGHANJONES, R. D. (1990). A HCO3-DEPENDENT MECHANISM REGULATES PHI FROM AN ACID LOAD IN ISOLATED SHEEP CARDIAC PURKINJE-FIBERS. In JOURNAL OF PHYSIOLOGY-LONDON Vol. 430 (pp. P74). Retrieved from https://www.webofscience.com/