Publications

August 2017

Probing medin monomer structure and its amyloid nucleation using 13 C-direct detection NMR in combination with structural bioinformatics
Davies, H.A., Rigden, D.J., Phelan, M.M., Madine, J. (2017). Probing medin monomer structure and its amyloid nucleation using 13 C-direct detection NMR in combination with structural bioinformatics. Scientific Reports. doi: 10.1038/srep45224.

DOSCATs: Double standards for protein quantification
Bennett, R.J., Simpson, D.M., Holman, S.W., Ryan, S., Brownridge, P., Eyers, C.E., Colyer, J., Beynon, R.J. (2017). DOSCATs: Double standards for protein quantification. Scientific Reports. doi: 10.1038/srep45570

Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells
Al-Sanabra, O., Duckworth, A.D., Glenn, M.A., Brown, B.R.B., Angelillo, P., Lee, K., Herbert, J., Falciani, F., Kalakonda, N., Slupsky, J.R. (2017) Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells. Scientific Reports. doi: 10.1038/srep43228

Evolutionary interplay between structure, energy and epistasis in the coat protein of the fX174 phage family
Redondo, R.A.F., De Vladar, H.P., Włodarski, T., Bollback, J.P. (2017) Evolutionary interplay between structure, energy and epistasis in the coat protein of the fX174 phage family. Journal of the Royal Society Interface. doi: 10.1098/rsif.2016.0139

 

August 2016

Absolute protein quantification of the yeast chaperome under conditions of heat shock
Mackenzie RJ, Lawless C, Holman SW, Lanthaler K, Beynon RJ, Grant CM, Hubbard SJ, Eyers CE (2016). Absolute protein quantification of the yeast chaperome under conditions of heat shock proteomics. Biochem J. doi: 10.1042/BCJ20160240

July 2016

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal
Horrell S, Antonyuk S.VEady R.RHasnain S, Hough MA, Strange RW (2016). Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal. IUCrJ. doi: 10.1107/S205225251600823X

June 2016

Emerging model systems for functional genomics analysis of Crassulacean acid metabolism
Hartwell JDever LVBoxall SF (2016) Emerging model systems for functional genomics analysis of Crassulacean acid metabolism. Current Opinion in Plant Biology 31: 100-108. doi:10.1016/j.pbi.2016.03.019.

April 2016

A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells
Trevino V, Cassese A, Nagy Z, Zhuang X, Herbert JAntczak PClarke K, Davies N, Rahman A, Campbell MJ, Guindani M, Bicknell R, Vannucci M, Falciani F (2016).  A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells. PLOS Computational Biology, doi:10.1371/journal.pcbi.1004884

Proteome dynamics: tissue variation in the kinetics of proteostasis in intact animals
Hammond DE, Claydon AJ, Simpson DMEdward DStockley PHurst JLBeynon RJ (2016) Proteome dynamics: tissue variation in the kinetics of proteostasis in intact animals. Molecular and Cellular Proteomics, Epub ahead of Print Feb 1.  doi:10.1074/mcp.M115.053488.

March 2016

Light Modulates the Biosynthesis and Organization of Cyanobacterial Carbon Fixation Machinery through Photosynthetic Electron Flow
Sun Y, Casella S, Fang Y, Huang F, Faulkner M, Barrett S, Liu LN (2016) Light modulates the biosynthesis and organization of cyanobacterial carbon fixation machinery through photosynthetic electron flow.  Plant Physiology, Epub ahead of Print March 8, 2016. DOI: 10.1104/pp.16.00107.

February 2016

Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition
Chavaunne T, Thorpe, Peffers MJ, Simpson D, Halliwell E, Screen HRC, Clegg PD (2016) Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition.  Scientific Reports 6, Article number: 20455, doi:10.1038/srep20455.

Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes
Murray B, Antonyuk SV, Marina A, Lu SC, Mato JM, Hasnain SS, Rojas AL (2016) Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes.  PNAS Feb 8 – Epub ahead of print doi/10.1073/pnas.1510959113.

Use of infrared microspectroscopy to elucidate a specific chemical signature associated with hypoxia levels found in glioblastoma
Sandt C, Nadaradjane C, Richards R, Dumas P, Sée V (2016)  Use of infrared microspectroscopy to elucidate a specific chemical signature associated with hypoxia levels found in glioblastoma.  Analyst 141(3): 870-873. doi: 10.1039/c5an02112j

January 2016

Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring
Lawless C, Holman SWBrownridge P, Lanthaler K, Harman VM, Watkins R, Hammond DE, Miller RL, Sims PF, Grant CM, Eyers CE,  Beynon RJ, Hubbard SJ (2016)  Direct and Absolute Quantification of over 1800 Yeast Proteins via Selected Reaction Monitoring. Molecular and Cellular Proteomics Jan 10. 

A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling
D’Amore R, Ijaz UZ, Schirmer M, Kenny JGGregory RDarby AC, Shakya M, Podar M, Quince C, Hall N (2016)  A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling.  BMC Genomics 17: 15, doi:10.1186/s12864-015-2194-9.

Cross-species proteomics in analysis of mammalian sperm proteins
Bayram HL, Claydon AJ, Brownridge PJHurst JL, Mileham A, Stockley PBeynon RJHammond DE (2016) Cross-species proteomics in analysis of mammalian sperm proteins.  J Proteomics. doi: 10.1016/j.jprot.2015.12.027.

A network pharmacology approach reveals new candidate caloric restriction mimetics in C
Calvert S, Tacutu R, Sharifi S, Teixeira R, Ghosh P, de Magalhaes JPD (2015) A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans.  Aging Cell Epub ahead of print. doi: 10.1111/acel.12432

Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.
Wood SH, van Dam S, Craig T, Tacutu R,, O’Toole A, Merry BJ, de Magalhaes JPD (2015) Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.  Genome Biology 16: 285. doi:10.1186/s13059-015-0847-2.

December 2015

Supergroup C Wolbachia, mutualist symbionts of filarial nematodes, have a distinct genome structure
Comandatore F, Cordaux R, Bandi C, Blaxter M, Darby A, Makepeace BL, Montagna M, Sassera D (2015).  Supergroup C Wolbachia, mutualist symbionts of filarial nematodes, have a distinct genome structure.  Open Biology 5(12). pii: 150099. PMID: 26631376. doi: 10.1098/rsob.150099. 

A genome-wide survey of DNA methylation in hexaploid wheat
Gardiner LJ, Quinton-Tulloch MQ, Olohan L, Price J, Hall N, Hall A (2015)  A genome-wide survey of DNA methylation in hexaploid wheat. Genome Biology. In Press. doi: 10.1186/s13059-015-0838-3.

Oxidative Stress Alters the Morphology and Toxicity of Aortic Medial Amyloid
Davies HA, Phelan MM, Wilkinson MC, Migrino RQ, Truran S, Franco DA, Liu LN, Longmore CJ, Madine J. Oxidative Stress Alters the Morphology and Toxicity of Aortic Medial Amyloid. Biophysical journal. 2015 Dec 1;109(11):2363-70. doi: 10.1016/j.bpj.2015.10.034

Mass spectrometry for structural analysis and quantification of the Major Urinary Proteins of the house mouse
Beynon RJ, Armstrong SD, Claydon AJ, Davidson AJ, Eyers CE, Langridge JI, Gómez-Baena G, Harman VM, Hurst JL, Lee V, McLean L, Pattison R, Roberts SA, Simpson DM, Unsworth J, Vonderach M, Williams JP, Woolerton YE (2015) Mass spectrometry for structural analysis and quantification of the Major Urinary Proteins of the house mouse. International Journal of Mass Spectrometry 2015 (in press). doi.org/10.1016/j.ijms.2015.07.026

Insights on cryoprotectant toxicity from gene expression profiling of endothelial cells exposed to ethylene glycol
Cordeiro RM, Stirling S, Fahy GM, de Magalhães JP. Insights on cryoprotectant toxicity from gene expression profiling of endothelial cells exposed to ethylene glycol. Cryobiology. 2015 Dec 31;71(3):405-12. doi: 10.3389/fnbeh.2015.00106

Redox proteomic analysis of the gastrocnemius muscle from adult and old mice.
McDonagh B, Sakellariou GK, Smith NT, Brownridge P, Jackson MJ. Redox proteomic analysis of the gastrocnemius muscle from adult and old mice. Data Brief. 2015 Jul 2;4:344-8. doi: 10.1016/j.dib.2015.06.012. eCollection 2015 Sep. PubMed PMID: 26217813; PubMed Central PMCID: PMC4510572. doi: 10.1016/j.dib.2015.06.012

Visualization of bacterial microcompartment facet assembly using high-speed atomic force microscopy
Sutter M, Faulkner M, Aussignargues C, Paasch BC, Barrett S, Kerfeld CA, Liu LN (2015)  Visualization of bacterial microcompartment facet assembly using high-speed atomic force microscopy.  Nano Letters. doi: 10.1021/acs.nanolett.5b04259.

Role of competition between polarity sites in establishing a unique front.
Wu C-F, Chiou J-G, Minakova M, Woods B, Tsygankov D, Zyla TR, Savage NS, Elston TC, Lew DJ (2015)  Role of competition between polarity sites in establishing a unique front. doi:http://dx.doi.org/10.7554/eLife.11611.

Transcriptomic Analysis of Shiga-Toxigenic Bacteriophage Carriage Reveals a Profound Regulatory Effect on Acid Resistance in Escherichia coli
Veses-Garcia M, Liu X, Rigden DJKenny JGMcCarthy AJAllison HE. Transcriptomic Analysis of Shiga-Toxigenic Bacteriophage Carriage Reveals a Profound Regulatory Effect on Acid Resistance in Escherichia coli. Applied and environmental microbiology. 2015 Dec 1;81(23):8118-25. doi: 10.1128/AEM.02034-15.

November 2015

Multi-level functional genomics data integration as a tool for understanding physiology: A network perspective.
Davidsen PK, Turan N, Egginton S, Falciani F (2015)  Multi-level functional genomics data integration as a tool for understanding physiology: A network perspective. Journal of Applied Physiology (1985) Nov 5:jap.01110.2014. doi: 10.1152/japplphysiol.01110.2014. 

Accuracy and Reproducibility in Quantification of Plasma Protein Concentrations by Mass Spectrometry without the Use of Isotopic Standards
Kramer G, Woolerton Y, van Straalen JP, Vissers JP, Dekker N, Langridge JI, Beynon RJ, Speijer D, Sturk A, Aerts JM. Accuracy and Reproducibility in Quantification of Plasma Protein Concentrations by Mass Spectrometry without the Use of Isotopic Standards. PLoS One. 2015 Oct 16; 10(10):e0140097. doi: 10.1371/journal.pone.0140097. eCollection 2015

Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence.
Perkins EJ, Antczak P, Burgoon L, Falciani F, Garcia-Reyero N, Gutsell S, Hodges G, Kienzler A, Knapen D, McBride M, Willett C (2015) Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence.  Toxicological Science Nov; 148(1):14-25. doi: 10.1093/toxsci/kfv181.

RNA-seq brings new insights to the intra-macrophage transcriptome of Salmonella Typhimurium
Srikumar S, Kroger C, Hebrard M, Colgan A, Owen SV, Sivasankaran SK, Cameron ADS, Hokamp K, Hinton JCD (2015).  RNA-seq brings new insights to the intra-macrophage transcriptome of Salmonella Typhimurium.   PLOS Pathogens Nov 12: 1-26: 20145. doi:10.1371/journal.ppat.1005262.

On predicting regulatory genes by analysis of functional networks in C.
Valba OV, Nechaev SK, Sterken MG, BastenSnoek L, Kammenga JE, Vasieva OO (2015) On predicting regulatory genes by analysis of functional networks in C. elegans, BioData Mining, 8:33. doi:10.1186/s13040-015-0066-0

October 2015

Systems Biology Approach Reveals a Calcium-Dependent Mechanism for Basal Toxicity in Daphnia magna
Antczak P, White TA, Giri A, Michelangeli F, Viant MR, Cronin MT, Vulpe C, Falciani F (2015). Systems Biology Approach Reveals a Calcium-Dependent Mechanism for Basal Toxicity in Daphnia magna. Environmental Science and Technology Sep 15;49(18). doi: 10.1021/acs.est.5b0270

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen PK, Viero G, Tebaldi T, Offenhäuser N, Rozman J, Rathkolb B, Neschen S, Klingenspor M, Wolf E, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Quattrone A, Falciani F and Biffo S (2015). eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nature Communications Sep 18;6:8261. doi: 10.1038/ncomms9261.

Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways.
Filer A, Antczak P, Parsonage GN, Legault HM, O'Toole M, Pearson MJ, Thomas AM, Scheel-Toellner D, Raza K, Buckley CD,  Falciani F (2011). Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways. PLoS One. Mar 25;10(3):e0120917. doi: 10.1371/journal.pone.0120917

Barley Hv circadian clock associated 1 and Hv photoperiod H1 are circadian regulators that can affect circadian rhythms in arabidopsis
Kusakina J, Rutterford Z, Cotter S, Marti MC, Laurie DA, Greenland AJ, Hall A, Webb AAR (2015).  Barley Hv circadian clock associated 1 and Hv photoperiod H1 are circadian regulators that can affect circadian rhythms in arabidopsis.  PLoSOne. doi: 10.1371/journal.pone.0127449

Transcriptomic analysis of shigatoxigenic bacteriophage carriage reveals a profound regulatory effect on E. coli acid resistance
Veses-Garcia M, Liu X, Rigden DJKenny JGMcCarthy AJ, Allison HE (2015). Transcriptomic analysis of shigatoxigenic bacteriophage carriage reveals a profound regulatory effect on E. coli acid resistance. Applied Environmental Microbiology Sep 18. pii: AEM.02034-15.  doi: 10.1128/AEM.02034-15.

The Genetic Basis of Kin Recognition in a Cooperatively Breeding Mammal
Green JP, Holmes AM, Davidson AJ, Paterson SStockley P, Beynon RJHurst JL. The Genetic Basis of Kin Recognition in a Cooperatively Breeding Mammal. Current Biology. 2015 Oct 19;25(20):2631-41. doi: 10.1016/j.cub.2015.08.045

Structural advances on titin: towards an atomic understanding of multi-domain functions in myofilament mechanics and scaffolding
Green JP, Holmes AM, Davidson AJ, Paterson S Stockley PBeynon RJ,  Hurst JL. The Genetic Basis of Kin Recognition in a Cooperatively Breeding Mammal. Current Biology. 2015 Oct 19;25(20):2631-41. doi: 10.1042/BST20150084.

September 2015

The mzqLibrary - An open source Java library supporting the HUPO-PSI quantitative proteomics standard
Qi D, Zhang H, Fan J, Perkins S, Pisconti A, Simpson DM, Bessant C, Hubbard S, Jones AR. The mzqLibrary–An open source Java library supporting the HUPO‐PSI quantitative proteomics standard. Proteomics. 2015 Sep 1;15(18):3152-62. doi: 10.1002/pmic.201400535.

A simple procedure for directly obtaining haplotype sequences of diploid genomes
Noyes HA, Daly D, Goodhead I, Kay S, Kemp SJ, Kenny JSaccheri I, Schnabel RD, Taylor JF, Hall N. A simple procedure for directly obtaining haplotype sequences of diploid genomes. BMC genomics. 2015 Aug 28;16(1):1. doi: 10.1186/s12864-015-1818-4.

HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors 
Sun C, Li Y, Taylor SE, Mao X, Wilkinson MC, Fernig DG. HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors. PeerJ. 2015 Jun 25;3:e1060doi: 10.7717/peerj.1060

August 2015

Representation of selected-reaction monitoring data in the mzQuantML data standard
Qi D, Lawless C, Teleman J, Levander F, Holman SW, Hubbard S, Jones AR. Representation of selected‐reaction monitoring data in the mzQuantML data standard. Proteomics. 2015 Aug 1;15(15):2592-6. doi: 10.1002/pmic.201400281

A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum
Krishna R, Xia D, Sanderson S, Shanmugasundram A, Vermont S, Bernal A, Daniel‐Naguib G, Ghali F, Brunk BP, Roos DS, Wastling JM. A large‐scale proteogenomics study of apicomplexan pathogens—Toxoplasma gondii and Neospora caninum. Proteomics. 2015 Aug 1;15(15):2618-28. doi: 10.1002/pmic.201400553

July 2015

Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions
Pandalaneni S, Karuppiah V, Saleem M, Haynes LP, Burgoyne RD, Mayans O, Derrick JP, Lian LY. Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions. Journal of Biological Chemistry. 2015 Jul 24;290(30):18744-56. doi: 10.1074/jbc.M114.627059

Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer 
Clarke K, Daubon T, Turan N, Soulet F, Zahari MM, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK. Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer. PLoS Genet. 2015 Jul 1;11(7):e1005325. doi: 10.1371/journal.pgen.

Heparan sulfate phage display antibodies recognise epitopes defined by a combination of sugar sequence and cation binding
Solari V, Rudd TR, Guimond SE, Powell AK, Turnbull JEYates EA. Heparan sulfate phage display antibodies recognise epitopes defined by a combination of sugar sequence and cation binding. Organic & biomolecular chemistry. 2015;13(21):6066-72. doi: 10.1039/c5ob00564g

June 2015

Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells. 
Nieves DJ, Li Y, Fernig DGLévy R. Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells. Royal Society open science. 2015 Jun 1;2(6):140454. doi: 10.1098/rsos.140454.

April 2015

Transcriptional changes during Daphnia pulex development indicate that the maturation decision resembles a rate more than a threshold
Harney E, Plaistow SJPaterson S. Transcriptional changes during Daphnia pulex development indicate that the maturation decision resembles a rate more than a threshold. Journal of evolutionary biology. 2015 Apr 1;28(4):944-58. doi: 10.1111/jeb.12624

The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner
Bailey FP, Byrne DP, Oruganty K, Eyers CE, Novotny CJ, Shokat KM, Kannan N, Eyers PA. The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner. Biochemical Journal. 2015 Apr 1;467(1):47-62. doi: 10.1042/BJ20141441

Divergent, Coexisting Pseudomonas aeruginosa Lineages in Chronic Cystic Fibrosis Lung Infections
Williams D, Evans B, Haldenby S, Walshaw MJ, Brockhurst MA, Winstanley C, Paterson S. Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections. American journal of respiratory and critical care medicine. 2015 Apr 1;191(7):775-85.

March 2015

The Fasciola hepatica genome: gene duplication and polymorphism in the Fasciola hepatica genome reveals adaptation to the host environment and the capacity for rapid evolution
Cwiklinski K, Dalton JP, Dufresne PJ, Course JL, Williams D, Hodgkinson J,  Paterson S. (2015). The Fasciola hepatica genome: gene duplication and polymorphism in the Fasciola hepatica genome reveals adaptation to the host environment and the capacity for rapid evolution.  Genome Biology, In Press.

Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae
Jarnuczak A, Eyers CE, Schwartz JM, Grant CM, Hubbard SJ (2015) Quantitative proteomics and network analysis of SSA1 and SSB1 deletion mutants reveals robustness of chaperone HSP70 network in Saccharomyces cerevisiae. Proteomics Feb 16. doi: 10.1002/pmic.201400527.  

A haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genome
Jordan KW, Wang S, Lun Y, Gardiner L-J, MacLachlan R, Hucl P, Wiebe K, Wong D, Forrest KL, Sharpe AG, Sidebottom CHD, Hall N, Toomajian C, Close T, Dubcovsky J, Akhunova A, Talbert L, Bansal UK, Bariana HS, Hayden MJ, Pozniak C, Jeddeloh JA, Hall A, Akhunov E and IWGS Consortium (2015). A haplotype map of allohexaploid wheat reveals distinct patterns of selection on homoeologous genome.  Genome Biology 16: 48. doi:10.1186/s13059-015-0606-4

Comparisons with Amyloid-beta Reveal an Aspartate Residue That Stabilizes Fibrils of the Aortic Amyloid Peptide Medin
Davies HAMadine J, Middleton DA. Comparisons with amyloid-β reveal an aspartate residue that stabilizes fibrils of the aortic amyloid peptide medin. Journal of Biological Chemistry. 2015 Mar 20;290(12):7791-803. doi: 10.1074/jbc.M114.602177.

Routine phasing of coiled-coil protein crystal structures with AMPLE
Thomas JM, Keegan RM, Bibby J, Winn MD, Mayans ORigden DJ. Routine phasing of coiled-coil protein crystal structures with AMPLE. IUCrJ. 2015 Mar 1;2(2):198-206. doi: 10.1107/S2052252515002080 

February 2015

Routine phasing of coiled-coil protein crystal structures with AMPLE. International Union of Crystallography Journal (In Press)
Thomas J, Keegan R, Bibby J, Winn M,  Mayans ORigden DJ. (2015).  Routine phasing of coiled-coil protein crystal structures with AMPLE. International Union of Crystallography Journal (In Press).

Sexual reproduction and genetic exchange in parasitic protists
Weedall GD, Hall N. Sexual reproduction and genetic exchange in parasitic protists. Parasitology. 2015 Feb 1;142(S1):S120-7. doi: 10.1017/S0031182014001693

January 2015

Exploring speed and performance of Molecular Replacement with AMPLE using QUARK ab initio protein models
Keegan R, Bibby J, Thomas J, Xu D, Zhang Y, Mayans O, Winn M, Rigden DJ (2015) Exploring speed and performance of Molecular Replacement with AMPLE using QUARK ab initio protein models. Acta Cryst. D (In press)

Antimalarial 4(1H)-pyridones bind to the Q(i) site of cytochrome bc(1)
Capper MJ, O’Neill PM, Fisher N, Strange RW, Moss D, Ward SA, Berry NG, Lawrenson AS, Hasnain SS, Biagini GA, Antonyuk SV. Antimalarial 4 (1H)-pyridones bind to the Qi site of cytochrome bc1. Proceedings of the National Academy of Sciences. 2015 Jan 20;112(3):755-60. doi: 10.1073/pnas.1416611112.

Transgenic Perturbation of the Decarboxylation Phase of Crassulacean Acid Metabolism Alters Physiology and Metabolism But Has Only a Small Effect on Growth 
Dever LV, Boxall SF, Kneřová J, Hartwell J. Transgenic perturbation of the decarboxylation phase of Crassulacean acid metabolism alters physiology and metabolism but has only a small effect on growth. Plant physiology. 2015;167(1):44-59. doi: 10.1104/pp.114.251827