MRes Advanced Biological Sciences Projects

The projects listed below are available to potential applicants considering applying to the MRes Advanced Biological Sciences programme in module LIFE706 Long Research Project (120 credits).  

Students undertake a project forming a major part of the Masters programme.  When you apply, please state your top three project preferences and the reason why, using the 'personal statement' section of the application form to explain your preferred choices. 

Available Projects

Projects below are listed in alphabetical order by supervisor.


Understanding the role of prophages in the control of bacterial host phenotypes

Supervisor: Dr Heather Allison


Structural and biochemical characterisation of novel proteins involved in sequestering heme in peridontal disease

Supervisor: Dr Svetlana Antonyuk


Combining adaptation and physiology to predict the pace of life in diverse animals

Supervisor: Professor David Atkinson


Impacts of warming on animal life histories and ecological processes

Supervisor: Professor David Atkinson


The role of mucin in trypanosome resistance in the bumblebee Bombus terrestris

Supervisor: Dr Seth Barribeau


Selfish DNA in evolution

Supervisor: Professor Andrea Betancourt


Sex determination in spider mites

Supervisor: Professor Andrea Betancourt


Synthetic biology applied to MAA production

Supervisor: Professor Mark Caddick


Novel photosynthetic pigment design and biosynthesis

Supervisor: Dr Daniel Canniffe


Impact of beneficial bacteria on host's biology

Supervisor: Dr Ewa Chrostek


Climate change and the evolution of insect mating systems    

Supervisor: Dr Stephen Cornell


Mapping the cyclic AMP signalling landscape in human vascular smooth muscle cell  

Supervisor: Professor Caroline Dart


The evolution of mate choice in moths and other animals

Supervisor: Dr Liam Dougherty


Investigating the composition and dynamics of norovirus replication complexes

Supervisor: Dr Edward Emmott


Regulation of norovirus infection by post-translational modification of viral proteins.

Supervisor: Dr Edward Emmott


Understanding the regulation of atypical phosphorylation in human disease

Supervisor: Professor Claire Eyers


Life-history strategies of parasites

Supervisor: Prof Andy Fenton


Wildlife Epidemiology

Supervisor: Prof Andy Fenton


Structure-function analysis of fibroblast growth factors (FGFs) - Project 1 

Supervisor: Prof Dave Fernig


Structure-function analysis of fibroblast growth factors (FGFs) - Project 2 

Supervisor: Prof Dave Fernig


Screening for inhibitors of sulfotransferases 

Supervisor: Prof Dave Fernig


The Role of Biotic Interactions in Driving Forest Regeneration and Expansion (GENETIC DIVERSITY)

Supervisor: Dr Cristina Garcia


Ecological, Genetic and Phenotypic Drivers of Forest Resilience to Climate Change

Supervisor: Dr Cristina Garcia


Floral Morphology and the Composition of the Pollinator Assemblage

Supervisor: Dr Cristina Garcia


The impact of honeybees on the reproductive biology of native species  

Supervisor: Dr Cristina Garcia


 The development of metabolic phenotyping and profiling for investigating antibiotic interactions in mono-cultures and mixed communities

Supervisor: Prof Roy Goodacre


Mobile genetic elements and bacterial evolution

Supervisor: Dr James Hall


Functional and comparative genomics of the highly water-use efficient Crassulacean acid metabolism adaptation of higher plant photosynthesis

Supervisor: Dr James Hartwell


The effect of metatasis-inducing proteins and the efficacy of new therapies targeting tumour progression in a chick embryo model

Supervisor: Dr Anne Herrmann


Conservation in fragmented landscapes under climate change

Supervisor: Dr Jenny Hodgson


Antimicrobial resistance in the staphylococci

Supervisor: Dr Mal Horsburgh


Heritable microbes as a component of animal and plant biology

Supervisor: Professor Greg Hurst


Understanding symbiotic interactions in invertebrates; Host-parasite biology; Evolution and behaviour; Microbiology; Dynamics and management of Host-Microbe interactions

Supervisor: Professor Greg Hurst


Identifying novel sites of post-translational modifications in proteins, and their role in e.g. signalling (plants) and cancer (human / model organisms)

Supervisor: Professor Andy Jones


Re-annotation of genomes using proteomics data   

Supervisor: Professor Andy Jones


The evolution of anti-predator defences induced by entomopathogenic nematodes

Supervisor: Dr Rebecca Jones


The effects of the microbiota on host behaviour

Supervisor: Professor Zen Lewis


Sexual selection in insects

Supervisor: Professor Zen Lewis


Mitochondria Dysfunction as a therapeutic target and drug design

Supervisor: Professor Lu-Yun Lian


Biogenesis, architecture and regulation of photosynthetic machinery

Supervisor: Professor Luning Liu


Does bacteria induce neurodgenerative diseases?

Supervisor: Dr Jill Madine


 Investigating mechanisms underlying aortic aneurysm and dissection

Supervisor: Dr Jill Madine


Utilising R-loop resolution in oncology

Supervisor: Dr Urszula McClurg


The role of SYCP1 in cancer cell biology and response to therapeutics

Supervisor: Dr Urszula McClurg


Investigating the role of meiotic TEX12 as a novel centrosomal protein

Supervisor: Dr Urszula McClurg


Determining the origin of mitotic centrosome

Supervisor: Dr Urszula McClurg


Characterisation of immune and stromal cell infiltrated in pancreatic tumours

Supervisor: Dr Ainhoa Mielgo Iza


Assessing wildlife disease dynamics

Supervisor: Dr David Montagnes


The role of interspecific interactions in shaping adaptive evolution in soil microbial communities

Supervisor: Dr Siobhan O'Brien


The role of multispecies interactions within the cystic fibrosis lung microbiome in shaping P. aeruginosa pathogenicity

Supervisor: Dr Siobhan O'Brien


The ecology and evolution of microbial public goods in a changing environment

Supervisor: Dr Siobhan O'Brien


The flexible genome - adaptation & plasticity in the anthropocene. Using butterflies & genomics to study adaptation to climate change

Supervisor: Dr Vicencio Oostra


How does ageing lead to macular degeneration? Study of functional interactions in the retinal pigment epithelium

Supervisor: Professor Luminita Paraoan


When and how to die or not to die: Novel protein-protein interactions driving apoptosis

Supervisor: Professor Luminita Paraoan


How does ageing lead to macular degeneration? Study of functional interactions in the retinal pigment epithelium

Supervisor: Prof Luminita Paraoan


Sexual selection in the bank vole genome

Supervisor: Professor Steve Paterson


Comparison of genomic variation in the ecological model Daphnia pulex

Supervisor: Professor Steve Paterson


Developing methods for genome assembly using long-read technology

Supervisor: Professor Steve Paterson


Understanding rapid adaptation; Non-genetic inheritance; Life-history evolution; Eco-evolutionary dynamics; Rapid adaptation and its ecological consequences

Supervisor: Dr Stewart Plaistow


Sex, death and selfish genes: gene drive in a fly

Supervisor: Dr Tom Price


Fertility in the face of climate change

Supervisor: Dr Tom Price


AMPLE: Innovative Bioinformatics approaches to molecular replacement

Supervisor: Professor Dan Rigden


Structural bioinformatics to shed light on genomic dark matter

Supervisor: Professor Dan Rigden


HIF and NH-KappaB crostalk

Supervisor: Professor Sonia Rocha


PhDs and the cell cycle

Supervisor: Professor Sonia Rocha


 

Mechanisms controlling gene expression in hypoxia and inflammation

Supervisor: Professor Sonia Rocha


Studying the counter-intuitive effect of bacteriostasis in bacterial persistence to antibiotics 

Supervisor: Dr Enrique Salcedo-Sora


Tackling Histoplasmosis; developing improved diagnostics for supporting disease control

Supervisor: Dr Claire Scantlebury


Hypoxia Inducible Factor Signalling: insights from live cell Imaging

Supervisor: Dr Violaine See


Discovery of new biomarkers for brain tumour stratification and treatment

Supervisor: Dr Violaine See


Understanding mechanism(s) of bacterial recognition by the host intestinal endocrine cells

Supervisor: Professor Soraya Shirazi-Beechey


Reproductive competition in mammals

Supervisor: Professor Paula Stockley


Small mammal conservation ecology

Supervisor: Professor Paula Stockley


The eco-immunology of wild mice

Supervisor: Professor Mark Viney


Exploiting natural genetic variation to improve shelf life in leafy brassicas

Supervisor: Dr Peter Walley


Evolutionary adaptation to climate change

Supervisor: Dr Raj Whitlock


Impacts of climate change on plant-soil interactions

Supervisor: Dr Raj Whitlock


Genomic responses to climate change in an ecological model species

Supervisor: Dr Raj Whitlock


Exploring protein-protein interactions to create a new gene therapy for Alzheimer's, Parkinson's and motor neuron diseases

Supervisor: Dr Gareth Wright


Interactions of host microbes with polysaccharides and their consequences for health and disease

Supervisor: Dr Edwin Yates


Sustainable Agriculture; aquaculture, aquaponics and associated sensor technologies

Supervisor: Dr Iain Young


Optimisation of hydroponic and aquaponic systems for urban farming

Supervisor: Dr Iain Young


Optimising husbandry, diet and feeding strategies for European Spiny Lobster (Palinurus elephas) in culture

Supervisor: Dr Iain Young


Beneficial plant-insect-microbe interactions in agricultural systems

Supervisor: Dr Sharon Zytynska


Seed inoculation methods for delivering beneficial microbes

Supervisor: Dr Sharon Zytynska