The aim of this module is to ensure that students are aware of fundamental principles of organic chemistry, including nomenclature, structure and bonding, and the basic principles of static and dynamic stereochemistry. The major reactions associated with the common functional groups will be covered with emphasis on reaction mechanisms. In addition, this module will provide an introduction to the basic techniques associated with practical synthetic chemistry.

(LO1) By the end of this module students will be able to infer and draw the structures and shapes of major classes of organic compounds needed in organic chemical reactions

(LO2) By the end of this module students will be able to explain the principles of bonding in major classes of organic compounds

(LO3) By the end of this module students will be able to apply the basic principles of stereochemistry to an array of acyclic and cyclic structures

(LO4) By the end of this module students will be able to predict the outcomes of simple chemical transformations for a range of important functional groups

(LO5) By the end of this module students will be able to illustrate the major classes of reaction mechanisms through the use of curly arrows

(LO6) By the end of the lab component, students will complete the basic techniques of synthetic chemistry (isolation, purification, identification, and design and work-up of reactions) and characterisation using spectroscopic techniques and chemical methods.

(LO7) Students will construct and judge student generated questions in relation to any aspect of course content to contribute to the collaborative and collective learning experience

(S1) Problem solving

(S2) Planning and time-management associated with practical work

(S3) Report Writing

Lectures. 60 x 1 hr. 54 core lectures (50 in-person & 4 asynchronous), 2 feedback lectures, 1 lab induction and 3 revision lectures.

Practical. The lab component of the course will be delivered in the early part of semester 2 and allow students to have a lab induction and 6 full days (39 hours) in the practical labs to develop their synthetic lab skills. Students work within a group and work closely with a demonstrator. Additional independent study is required to help with laboratory preparation.

Workshops. 12 x 2 hr. Students will be supported through 12 active workshops throughout the year. The first session of each semester will be a PC session, introducing students to core tools they'll need throughout their organic chemistry curriculum (ChemDraw,ChemTube3D and analytical tools such as TopSpin and OpenChrom), with the remaining sessions taking place in smaller in-person workshops. All sessions are supported by demonstrators. Students will have access to the workshop problem sheets in advance with the problems closely aligned to the lecture material delivered in the preceding weeks. The workshops will be formative, involving a mixture of in-class assessments, small group tasks and submissions after class.

Coursework. Peerwise assessment. This process will take place once in each semester. Students will generate questions in groups embracing the concepts of peer review followed by answering questions individually.

*Lectures: 60 hr
*Practical: 39 hr
*Workshops: 24 hr

Lectures
Organic structures
Organic reactions
Delocalization and conjugation
Acidity, basicity, and pKa
Using organometallic reagents to make C-C bonds
Nucleophilic substitution at the carbonyl (C=O) group
Nucleophilic substitution at C=O with loss of carbonyl oxygen
Stereochemistry
Nucleophilic substitution at saturated carbon
Conformational analysis
Elimination reactions
Electrophilic addition to alkenes
Electrophilic aromatic substitution
Formation and reactions of enols and enolates

Practical
The laboratory course will cover the basic techniques of preparative chemistry which potentially includes but is not limited to-
•Recrystallisation from single and mixed solvents, filtration
•Determination of m.p., m.m.p. and use of I.R. for identification
•Separation of acid/base/neutral compounds using extraction etc., use of rotary evaporator
•TLC and GC for meas ure of purity and for following a reaction
•Use of NMR
•Distillation at atmospheric pressure
•Chemoselective reductions of 3-nitroacetophenone
• A simple oxidation reaction analysed by GC