Module Details
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title Organic Chemistry for Pharmacology
Code CHEM038
Coordinator Dr A Sergeev
Chemistry
A.Sergeev@liverpool.ac.uk
Year CATS Level Semester CATS Value
Session 2022-23 Level 5 FHEQ Second Semester 15

Pre-requisites before taking this module (or general academic requirements):
LIFE104 BIOLOGICAL CHEMISTRY 

Aims

The aim of this module is to offer students a grounding in organic chemistry and spectroscopy that is directly relevant to Pharmacology.
There will be a particular emphasis on relating each topic studied to pharmacological examples.

Learning Outcomes

(LO1) Upon successful completion of this module, a student will be able to demonstrate an understanding of the structure and bonding in a range of molecules, from simple organics to larger biologically relevant structures.

(LO2) Upon successful completion of this module, a student will be able to demonstrate an understanding of the significant role of stereochemistry and conformation in a pharmacological setting

(LO3) Upon successful completion of this module, a student will be able to demonstrate an understanding of an array of chemical reactions

(LO4) Upon successful completion of this module, a student will be able to demonstrate an understanding of a range of spectroscopic methods

(LO5) Upon successful completion of this module, a student will be able to demonstrate an understanding of the chemical principles in both the synthesis of biologically relevant structures

(LO6) Upon successful completion of this module, a student will be able to apply these concepts and principles to process and solve unseen organic chemistry problems.

(S1) Improving own learning/performance - Reflective practice

(S2) Critical thinking and problem solving - Problem identification

(S3) Personal attributes and qualities - Resilience

(S4) Students will develop independent learning and self-evaluation skills

Teaching and Learning Strategies

The course will be taught through a series of online asynchronous lectures (equivalent to 28 hours with additional revisions sessions).
These are supported by 5 in-person workshops throughout the term to give students the opportunity to obtain immediate and directed feedback.
A mid-term class test will allow students to see how they are progressing.

*Lectures: 31 hr
*Coursework: 12.5 hr

Syllabus
 

Structure, bonding and basic reactivity
• General revision of various concepts

Stereochemistry
• Absolute configuration
• Diastereoisomers
• Conformation of cyclic systems, including hexoses and pentoses

Chemical reactions
• Substitution and elimination reactions
• Alkene addition
• Carbonyl chemistry
• C-C bond forming reactions (aldol/Claisen)

Biological Chemistry
• Amino acids and proteins: Synthesis and interactions

Spectroscopy
• Mass spectrometry
• Ultraviolet-visible spectroscopy
• Infrared spectroscopy
• Nuclear magnetic resonance

Recommended Texts
Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module.

Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours           31

12.5

 43.5
Timetable (if known)              
Private Study 105.5
TOTAL HOURS 149

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
On-line time controlled final examination. The examination can be completed in two hours. An additional hour has been included to allow for uploading of final solutions.  180    70       
mid-term class test. on-line, time controlled assessment. One hour on task plus 1 hr to upload.  120    20       
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
5 in-person workshops. Marked in class.  0    10