Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | An Introduction to Medicinal Chemistry | ||
Code | CHEM248 | ||
Coordinator |
Professor PM O'Neill Chemistry P.M.Oneill01@liverpool.ac.uk |
||
Year | CATS Level | Semester | CATS Value |
Session 2021-22 | Level 5 FHEQ | Second Semester | 7.5 |
Pre-requisites before taking this module (or general academic requirements): |
Aims |
|
The aim of this module is to introduce students to the fundamental principles that underpin modern medicinal chemistry, including an introduction to targets for drug action, methods of administration, qualitative and quantitative SAR, computer aided molecular design, solid phase chemistry /combinatorial chemistry. The course will also introduce approaches to the design of high quality hits using parameters such as Ligand Efficiency, Lipophilic Ligand Efficiency, Property Forecast Indexing and will provide some introductory carbohydrate chemistry. |
Learning Outcomes |
|
(LO1) By the end of this module students are expected to have acquired an understanding of |
|
(S1) Students will develop their chemistry-related cognitive abilities and skills, ie abilities and skills relating to intellectual tasks, including problem-solving as required by the Chemistry subject benchmark statement. In particular, they will gain the ability to adapt and apply methodology to the solution of unfamiliar problems. |
|
(S2) Communication skills through online Teams Meetings |
|
(S3) Organisational skills |
Teaching and Learning Strategies |
|
Lectures. These will be delivered in-person .Selected lectures will have discussion points and questions which will be covered in following lectures. Formative MCQ will be posted online in Canvas. Coursework. Two assignments with marked work returned to students, supported by two feedback sessions on MS Teams (2 x 1 hr). *Lectures: 14 hr |
Syllabus |
|
Lecture 1 Structures of Proteins: Bonds/ Energies Involved in Drug Receptor Interactions Introduction to Medicinal Chemistry: |
Recommended Texts |
|
Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
14 |
4 2 |
20 | ||||
Timetable (if known) | |||||||
Private Study | 55 | ||||||
TOTAL HOURS | 75 |
Assessment |
||||||
EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
unseen closed-book written examination Marked Anonymously | 90 | 80 | ||||
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Two Assignments | 0 | 20 |