Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | Asymmetric Catalysis for Organic and Pharmaceutical Chemistry | ||
Code | CHEM496 | ||
Coordinator |
Prof J Xiao Chemistry J.Xiao@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2019-20 | Level 7 FHEQ | Second Semester | 7.5 |
Pre-requisites before taking this module (or general academic requirements): |
Aims |
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The aim of the module is to introduce students to the main aspects of asymmetric catalysis and its application in synthetic organic chemistry. Students will gain: |
Learning Outcomes |
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(LO1) An understanding of the importance of asymmetric catalysis in chemical synthesis. |
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(LO2) An understanding of the fundamental principles and mechanisms of asymmetric catalysis. |
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(LO3) A grasp of the various aspects of asymmetric catalysis ranging from metal-catalysed redox reactions through kinetic resolution to oranocatalytic C-C bond formation. |
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(LO4) An understanding of the applications of asymmetric catalysis in fine chemicals and pharmaceutical synthesis. |
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(LO5) An ability to evaluate the experimental evidence for and against a proposed mechanism for an asymmetric catalytic reaction |
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(LO6) An ability to propose a rational synthetic pathway for a specific chiral molecule |
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(LO7) An ability to propose a likely mechanism for a new asymmetric catalytic reaction. |
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(LO8) An opportunity to consider new developments in the field, especially those that feature new concepts and/or underpin new environmentally benign processes. |
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(S1) Students will develop their chemistry-related cognitive abilities and skills, i.e. abilities and skills relating to intellectual tasks, including problem-solving as required by the Chemistry subject benchmark statement. In particular, at master's level, they will gain the ability to adapt and apply methodology to the solution of unfamiliar problems. |
Teaching and Learning Strategies |
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15 lectures, accompanied by 3 tutorials sessions. |
Syllabus |
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1. Introduction to asymmetric catalysis 2. Asymmetric hydrogenation 3. Asymmetric isomerisation 4. Asymmetric oxidation 5. Asymmetric C-C bond formation 6. Introduction to asymmetric organocatalysis 7. Kinetic resolution 8. Dynamic kinetic resolution |
Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
15 |
3 |
18 | ||||
Timetable (if known) | |||||||
Private Study | 57 | ||||||
TOTAL HOURS | 75 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Formal Examination | 120 minutes | 100 | ||||
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |