Photo of Dr Kristian Daly

Dr Kristian Daly B.Sc., Ph.D

Post-Doctoral Research Fellow Infection Biology & Microbiomes

    Publications

    Selected Publications

    1. Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion (Journal article - 2013)
    2. Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease (Journal article - 2012)
    3. Microarray analysis of butyrate regulated genes in colonic epithelial cells. (Journal article - 2006)
    4. The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homeostasis. (Journal article - 2005)

    2021

    Non-nutritive sweetener activation of the pig sweet taste receptor T1R2-T1R3 in vitro mirrors sweetener stimulation of the gut-expressed receptor in vivo (Journal article)

    Daly, K., Moran, A. W., Al-Rammahi, M., Weatherburn, D., & Shirazi-Beechey, S. P. (2021). Non-nutritive sweetener activation of the pig sweet taste receptor T1R2-T1R3 in vitro mirrors sweetener stimulation of the gut-expressed receptor in vivo. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 542, 54-58. doi:10.1016/j.bbrc.2021.01.032

    DOI: 10.1016/j.bbrc.2021.01.032

    Nutrient sensing of gut luminal environment (Journal article)

    Moran, A., Daly, K., Al-Rammahi, M., & Shirazi-Beechey, S. (n.d.). Nutrient sensing of gut luminal environment. Proceedings of the Nutrition Society. doi:10.1017/S0029665120007120

    DOI: 10.1017/S0029665120007120

    2020

    Toll-like receptor 9 expressed in proximal intestinal enteroendocrine cells detects bacteria resulting in secretion of cholecystokinin (Journal article)

    Daly, K., Burdyga, G., Al-Rammahi, M., Moran, A. W., Eastwood, C., & Shirazi-Beechey, S. P. (2020). Toll-like receptor 9 expressed in proximal intestinal enteroendocrine cells detects bacteria resulting in secretion of cholecystokinin. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 525(4), 936-940. doi:10.1016/j.bbrc.2020.02.163

    DOI: 10.1016/j.bbrc.2020.02.163

    Consumption of a Natural High-Intensity Sweetener Enhances Activity and Expression of Rabbit Intestinal Na+/Glucose Cotransporter 1 (SGLT1) and Improves Colibacillosis-Induced Enteric Disorders (Journal article)

    Shirazi-Beechey, S. (2020). Consumption of a Natural High-Intensity Sweetener Enhances Activity and Expression of Rabbit Intestinal Na+/Glucose Cotransporter 1 (SGLT1) and Improves Colibacillosis-Induced Enteric Disorders. Journal of Agricultural and Food Chemistry. doi:10.1021/acs.jafc.9b04995

    DOI: 10.1021/acs.jafc.9b04995

    2019

    The effect of milk replacer composition on the intestinal microbiota of pre-ruminant dairy calves (Journal article)

    Badman, J., Daly, K., Kelly, J., Moran, A., Cameron, J., Watson, I., . . . Shirazi-Beechey, S. P. (2019). The effect of milk replacer composition on the intestinal microbiota of pre-ruminant dairy calves. Frontiers in Veterinary Science. doi:10.3389/fvets.2019.00371

    DOI: 10.3389/fvets.2019.00371

    Host selectively contributes to shaping intestinal microbiota of carnivorous and omnivorous fish (Journal article)

    Daly, K., Kelly, J., Moran, A., Bristow, R., Young, I., Cossins, A., . . . Shirazi-Beechey, S. (2019). Host selectively contributes to shaping intestinal microbiota of carnivorous and omnivorous fish. The Journal of General and Applied Microbiology, 65(3), 129-136. doi:10.2323/jgam.2018.07.003

    DOI: 10.2323/jgam.2018.07.003

    2018

    Sweet Sensing by Gut Bacteria (Performance)

    Daly, K. P. (2018, July 11). Sweet Sensing by Gut Bacteria [Invited Oral Presentation]. American Society of Animal Sciences Annual Meeting, Vancouver, Canada.

    2017

    Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals (Journal article)

    Wolnerhanssen, B. K., Moran, A. W., Burdyga, G., Meyer-Gerspach, A. C., Peterli, R., Manz, M., . . . Shirazi-Beechey, S. P. (2017). Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals. Scientific Reports, 7. doi:10.1038/s41598-017-08487-9

    DOI: 10.1038/s41598-017-08487-9

    Role of intestinal nutrient sensors in secretion of satiety hormones regulating appetite (Performance)

    Daly, K. P., & Shirazi-Beechey, S. P. (2017, July 10). Role of intestinal nutrient sensors in secretion of satiety hormones regulating appetite [Presentation]. Baltimore, Maryland, USA.

    Composition and diversity of mucosa-associated microbiota along the entire length of the pig gastrointestinal tract; dietary influences. (Journal article)

    Kelly, J., Daly, K., Moran, A., Ryan, S., Bravo, D., & Shirazi-Beechey, S. P. (2017). Composition and diversity of mucosa-associated microbiota along the entire length of the pig gastrointestinal tract; dietary influences.. Environmental Microbiology, 19(4), 1425-1438. doi:10.1111/1462-2920.13619

    DOI: 10.1111/1462-2920.13619

    2016

    Low calorie sweeteners and gut microbiota (Journal article)

    Daly, K., Darby, A. C., & Shirazi-Beechey, S. P. (2016). Low calorie sweeteners and gut microbiota. PHYSIOLOGY & BEHAVIOR, 164, 494-500. doi:10.1016/j.physbeh.2016.03.014

    DOI: 10.1016/j.physbeh.2016.03.014

    2015

    Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus (Journal article)

    Daly, K., Darby, A., Hall, N., Wilkinson, M., Pongchaikul, P., Bravo, D., & Shirazi-Beechey, S. (2015). Bacterial sensing underlies artificial sweetener-induced growth of gut Lactobacillus. Environmental Microbiology, 18(7), 2159-2171. doi:10.1111/1462-2920.12942

    DOI: 10.1111/1462-2920.12942

    2014

    Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing. (Journal article)

    Shirazi-Beechey, S., Daly, K., Al-Rammahi, M., Moran, A., & Bravo, D. (2014). Role of nutrient-sensing taste 1 receptor (T1R) family members in gastrointestinal chemosensing.. The British journal of nutrition, 111(S1), S8-S15. doi:10.1017/S0007114513002286

    DOI: 10.1017/S0007114513002286

    Characterization of the pig sweet taste receptor by heterologous expression (Performance)

    Daly, K., Shirazi-Beechey, S., & Daly, K. (2014). Characterization of the pig sweet taste receptor by heterologous expression [Public Performance].

    Dietary supplementation with lactose or artificial sweetener enhances swine gut Lactobacillus population abundance. (Journal article)

    Daly, K., Darby, A., Hall, N., Nau, A., Bravo, D., & Shirazi-Beechey, S. (2014). Dietary supplementation with lactose or artificial sweetener enhances swine gut Lactobacillus population abundance.. The British Journal of Nutrition, 111(S1), S30-S35. doi:10.1017/S0007114513002274

    DOI: 10.1017/S0007114513002274

    2013

    Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion (Journal article)

    Daly, K., Al-Rammahi, M., Moran, A., Marcello, M., Ninomiya, Y., & Shirazi-Beechey, S. P. (2013). Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 304(3), G271-G282. doi:10.1152/ajpgi.00074.2012

    DOI: 10.1152/ajpgi.00074.2012

    2012

    Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transport (Journal article)

    Daly, K., Al-Rammahi, M., Arora, D. K., Moran, A. W., Proudman, C. J., Ninomiya, Y., & Shirazi-Beechey, S. P. (2012). Expression of sweet receptor components in equine small intestine: relevance to intestinal glucose transport. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 303(2), R199-R208. doi:10.1152/ajpregu.00031.2012

    DOI: 10.1152/ajpregu.00031.2012

    Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease (Journal article)

    Daly, K., Proudman, C. J., Duncan, S. H., Flint, H. J., Dyer, J., & Shirazi-Beechey, S. P. (2012). Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease. British Journal of Nutrition, 107(7), 989-995. doi:10.1017/s0007114511003825

    DOI: 10.1017/s0007114511003825

    Sweet sensing by swine gut lactobacilli enhances their growth and population abundance (Performance)

    Daly, K. (2012). Sweet sensing by swine gut lactobacilli enhances their growth and population abundance [Public Performance].

    Sweet sensing by swine gut lactobacillus enhances its growth and population abundance (Performance)

    Daly, K. (2012). Sweet sensing by swine gut lactobacillus enhances its growth and population abundance [Public Performance].

    Sweet sensing by swine gut lactobacillus enhances its growth and population abundance (Performance)

    Daly, K. (2012). Sweet sensing by swine gut lactobacillus enhances its growth and population abundance [Public Performance].

    2011

    Glucose sensing and signalling; regulation of intestinal glucose transport (Journal article)

    Shirazi-Beechey, S. P., Moran, A. W., Batchelor, D. J., Daly, K., & Al-Rammahi, M. (2011). Glucose sensing and signalling; regulation of intestinal glucose transport. PROCEEDINGS OF THE NUTRITION SOCIETY, 70(2), 185-193. doi:10.1017/S0029665111000103

    DOI: 10.1017/S0029665111000103

    Effect of dietary change on equine and swine gut microbiota (Performance)

    Daly, K. (2011). Effect of dietary change on equine and swine gut microbiota [Public Performance].

    2010

    Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners (Journal article)

    Moran, A. W., Al-Rammahi, M. A., Arora, D. K., Batchelor, D. J., Coulter, E. A., Daly, K., . . . Shirazi-Beechey, S. P. (2010). Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners. BRITISH JOURNAL OF NUTRITION, 104(5), 637-646. doi:10.1017/S0007114510000917

    DOI: 10.1017/S0007114510000917

    Effect of diet on equine gut microbiota (Performance)

    Daly, K. (2010). Effect of diet on equine gut microbiota [Public Performance].

    Nutrient sensing mechanisms underlying CCK release (Performance)

    Daly, K. (2010). Nutrient sensing mechanisms underlying CCK release [Public Performance].

    2008

    Identification of the butyrate/cytokine response element of the monocarboxylate transporter 1 gene (Performance)

    Daly, K. (2008). Identification of the butyrate/cytokine response element of the monocarboxylate transporter 1 gene [Public Performance].

    2007

    Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation (Journal article)

    Thibault, R., de Coppet, P., Daly, K., Bourreille, A., Cuff, M. A., Bonnet, C., . . . Segain, J. P. (2007). Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation. Gastroenterolgy, 133, 1916-1927.

    Intestinal glucose sensing and regulation of intestinal glucose absorption. (Journal article)

    Dyer, J., Daly, K., Salmon, K. S., Arora, D. K., Kokrashvili, Z., Margolskee, R. F., & Shirazi-Beechey, S. P. (2007). Intestinal glucose sensing and regulation of intestinal glucose absorption.. Biochemical Society Transactions, 35, 1191-1194.

    T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. (Journal article)

    Margolskee, R. F., Dyer, J., Kokrashvili, Z., Salmon, K. S. H., Ilgemes, E., Daly, K., . . . Shirazi-Beechey, S. P. (2007). T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.. Proceedings of the National Acadamy of Sciences USA, 104, 15075-15080.

    2006

    Microarray analysis of butyrate regulated genes in colonic epithelial cells. (Journal article)

    Daly, K., & Shirazi-Beechey, S. P. (2006). Microarray analysis of butyrate regulated genes in colonic epithelial cells.. DNA and Cell Biology, 25, 49-62.

    2005

    The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homeostasis. (Journal article)

    Daly, K., Cuff, M. A., Fung, F., & Shirazi-Beechey, S. P. (2005). The importance of colonic butyrate transport to the regulation of genes associated with colonic tissue homeostasis.. Biochemical Society Transactions, 33, 733-735.

    2003

    Design and evaluation of group-specific oligonucleotide probes for quantitative analysis of intestinal ecosystems: their application to assessment of equine colonic microflora (Journal article)

    Daly, K., & Shirazi-Beechey, S. P. (2003). Design and evaluation of group-specific oligonucleotide probes for quantitative analysis of intestinal ecosystems: their application to assessment of equine colonic microflora. FEMS Microbiology Ecology, 44(2), 243-252. doi:10.1016/s0168-6496(03)00032-1

    DOI: 10.1016/s0168-6496(03)00032-1

    2001

    Bacterial diversity within the equine large intestine as revealed by molecular analysis of cloned 16S rRNA genes (Journal article)

    Daly, K. P., Stewart, C. S., Flint, H. J., & Shirazi-Beechey, S. P. (2001). Bacterial diversity within the equine large intestine as revealed by molecular analysis of cloned 16S rRNA genes. FEMS Microbiology Ecology, 38, 141-151. doi:10.1111/j.1574-6941.2001.tb00892

    DOI: 10.1111/j.1574-6941.2001.tb00892

    Isolation and characterization of a novel hydrocarbon-degrading, Gram-positive bacterium, isolated from intertidal beach sediment, and description of Planococcus alkanoclasticus sp. nov. (Journal article)

    Engelhardt, M. A., Daly, K. P., Swannell, R. P., & Head, I. M. (2001). Isolation and characterization of a novel hydrocarbon-degrading, Gram-positive bacterium, isolated from intertidal beach sediment, and description of Planococcus alkanoclasticus sp. nov.. Journal of Applied Microbiology, 90(2), 237-247. doi:10.1046/j.1365-2672.2001.01241

    DOI: 10.1046/j.1365-2672.2001.01241

    2000

    Development of oligonucleotide probes and PCR primers for detecting phylogenetic subgroups of sulfate-reducing bacteria (Journal article)

    Daly, K., Sharp, R. J., & McCarthy, A. J. (2000). Development of oligonucleotide probes and PCR primers for detecting phylogenetic subgroups of sulfate-reducing bacteria. Microbiology, 146(7), 1693-1705. doi:10.1099/00221287-146-7-1693

    DOI: 10.1099/00221287-146-7-1693

    1997

    Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes. (Journal article)

    Daly, K. P., Dixon, A. C., Swannell, R. P., Lepo, J. E., & Head, I. M. (1997). Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.. Journal of Applied Microbiology, 83(4), 421-429. doi:10.1046/j.1365-2672.1997.00254

    DOI: 10.1046/j.1365-2672.1997.00254

    Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes. (Journal article)

    Daly, K. P., Dixon, A. C., Swannell, R. P., Lepo, J. E., & Head, I. M. (1997). Diversity among aromatic hydrocarbon-degrading bacteria and their meta-cleavage genes.. Journal of Applied Microbiology, 83(4), 421-429. doi:10.1046/j.1365-2672.1997.00254

    DOI: 10.1046/j.1365-2672.1997.00254