I am a postdoc in the Microbial Evolution, Genomics and Adaptation group based in the Institute of Infection, Veterinary and Ecological Sciences. My main research interests are in understanding the genetic basis of niche adaptation in bacterial pathogens of the respiratory tract. The ultimate aim of my research is to identify genes which are essential for bacteria to switch from a commensal to a pathogenic lifestyle and then target these genes in the future development of therapeutics and vaccines. I am also interested in understanding the importance of bacterial metabolism in niche colonisation.
My PhD was based at Cardiff University and was in collaboration with Unilever. My research used a combination of whole genome sequencing, transposon mutagenesis, RNA-Seq and genome-scale metabolic modelling to identify key genetic pathways involved in industrial Pseudomonas aeruginosa preservative resistance.