Mrs Jan Brett B.Sc., M.Sc., CSci, MISTR, FIScT.

Research Overview

Publications
Selective modulation of neuronal nicotinic acetylcholine receptor channel subunits by G0- protein subunits. Fischer H, Lie DM, Harries JC, Adams DJ. J Neurosci. 2005 Apr6; 25(14):3571-7

N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo. Polanska UM, Duschesne L, Harries JC, Fernig DG, Kinnunen TK. J Biol Chem 2009 Nov 27; 284(48):33030-9

Functional interaction of CREB binding protein (CBP) with nuclear transport proteins and modulation by HDAC inhibitors. Ryan CM, Harries JC, Kindle KB, Collins HM, Heery DM. Cell Cycle. 2006 Sep; 5(19):2146-52

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1. Sheppard HM, Harries JC, Hussain S, Bevan C, Heery DM. Mol Cell Biol. 2001 Jan; 21(1):39-50

Transcriptional activation by estrogen receptor (ERalpha) and steroid receptor coactivator (SRC1) involves distinct mechanisms in yeast and mammalian cells. Sheppard HM, Matsuda S, Harries JC, Kindle KB, Heery DM. J Mol Endocrinol. 2003 Jun; 0(3):411-22

A conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP. Matsuda S, Harries JC, Viskaduraki M, Troke PJ, Kindle KB, Ryan C, Heery DM. J boil Chem. 2004 Apr. 2; 279(14):14055-64

T- levels and our future technicians - Jan Brett
https://istonline.org.uk/cms/wp-content/uploads/2022/12/ist-journal-2022-final.pdf