Gram-negative Bacterial Pathogens

Recent Publications

  • Ashish, A., Shaw, M., Winstanley, C., Ledson, M.J., and Walshaw, M.J. (2012).  Increasing resistance of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa (Psa) to antibiotics in cystic fibrosis (CF) – A cause for concern?  Journal of Cystic Fibrosis 11:173-179. 
  • Fothergill, J.L., Walshaw, M.J. and Winstanley, C. (2012). Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis lung infections.  European Respiratory Journal (in press).
  • Fothergill, J.L., Winstanley, C. and James, C.E. (2012). Novel therapeutic strategies to counter Pseudomonas aeruginosa infections.  Expert Reviews of Anti-Infective Therapy 10:219–235.
  •  Ashish, A., Shaw, M., Winstanley, C., Ledson, M.J., and Walshaw, M.J. (2012).  Increasing resistance of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa (Psa) to antibiotics in cystic fibrosis (CF) – A cause for concern?  Journal of Cystic Fibrosis (in press).
  • Kirchner, S., Fothergill, J.L., Wright E.A, James, C.E., Mowat, E. and Winstanley, C.* (2012).  Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant to the cystic fibrosis lung.  Journal of Visualized Experiments (in press).
  • Roberts, C.L., Keita, A.V., Parsons, B.N., Prorok-Hamon, M., Knight, P., Winstanley, C., O’Kennedy, N., Soderholm, J.D., Rhodes, J.M. and Campbell, B.J. (2012).  Soluble plantain fibre blocks adhesion and M-cell translocation of intestinal pathogens. Journal of Nutritional Biochemistry (in press).  IF 4.5.
  • Mowat, E., Paterson, S., Fothergill, J.L., Wright, E.A., Ledson, M.J., Walshaw, M.J., Brockhurst, M.A. and Winstanley, C.* (2011).  High phenotypic diversity and dynamic turnover in chronic Pseudomonas aeruginosa infections of cystic fibrosis patients.  American Journal of Respiratory and Critical Care Medicine 183:1674-1679.  IF 10.2.
  • Hepworth, P.J., Ashelford, K.E., Hinds, J., Gould, K.A., Witney, A.A., Williams, N.J., Leatherbarrow, H., French, N.P., Birtles, R.J., Mendonca, C., Dorrell, N., Wren, B.W., Wigley, P., Hall, N. and Winstanley, C.* (2011).  Genomic variations define divergence of water / wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes.  Environmental Microbiology 13:1549-1560. IF 5.5.
  • Silby, M.W.*, Winstanley, C., Godfrey, S.A.C., Levy, S.B., and Jackson, R.W. (2011).  Pseudomonas genomes: diverse and adaptable.  FEMS Microbiology Reviews 35:652-680.
  • Stewart, R.M.K., Wiehlmann, L., Ashelford, K.E., Preston, S., Frimmersdorf, E., Campbell, B.J., Neal, T.J., Hall, N., Tuft, S., Kaye, S.B., and Winstanley, C.* (2011).  Genetic characterization indicates a specific sub-population of Pseudomonas aeruginosa associated with keratitis infections.  Journal of Clinical Microbiology 49:993-1003. IF 4.2.
  • Merga, J.Y., Leatherbarrow, A.J.H., Winstanley, C., Bennett, M., Hart, C.A., Miller, W.G. and Willams, N.J.* (2011).  A Comparison of Arcobacter isolation methods and the diversity of Arcobacter spp. in Cheshire, UK.  Applied and Environmental Microbiology 77:1646-1650. IF 3.8.
  • Fothergill, J.L., Mowat, E., Walshaw, M.J., Ledson, M.J., James, C.E. and Winstanley, C.* (2011).  The effect of antibiotic treatment on bacteriophage production by a cystic fibrosis epidemic strain of  Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 55:426-428. IF 4.7.
  • Williams, N.J*., Jones, T.R., Leatherbarrow, H.J., Birtles, R.J., Lahuerta-Marin, A., Bennett, M. and Winstanley, C. (2010). Isolation of a novel Campylobacter jejuni clone associated with the bank vole Myodes glareolus. Applied and Environmental Microbiology 76:7318-7321. IF 3.8.
  • Carter, M., Fothergill, J.L., Walshaw, M.J., Rajakumar, K., Kadioglu, A. and Winstanley, C.* (2010).  A sub-type of a Pseudomonas aeruginosa cystic fibrosis epidemic strain exhibits enhanced virulence in a murine model of acute respiratory infection. Journal of Infectious Diseases 202:935-942. IF 6.3.
  • Fothergill, J.L, White, J., Foweraker, J.E., Walshaw, M.J., Ledson, M.J., Mahenthiralingam, E. and Winstanley, C.* (2010). Impact of Pseudomonas aeruginosa genomic instability on the application of typing methods in chronic cystic fibrosis infections.  Journal of Clinical Microbiology 48:2053-2059. IF 4.2.
  • Mohan, K.*, Lakshman, V., Fothergill, J.L., Ledson, M.J., Winstanley, C., Walshaw, M.J. (2010).  Empyema due to a highly transmissible Pseudomonas aeruginosa strain in an adult cystic fibrosis patient.  Journal of Medical Microbiology 59:614-616. IF 2.4.
  • Floyd, R.V., Winstanley, C., Bakran, A., Wray, S. and Burdyga, T.V.* (2010).  Uropathogenic Escherichia coli (UPEC) modulate ureteric Ca signalling and contractility in humans and rats.  American Journal of Physiology – Renal Physiology 298:900-908.  IF 3.8.
  • Fothergill, J.L., Mowat, E., Ledson, M.J., Walshaw, M.J., Winstanley, C.* (2010). Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations.  Journal of Medical Microbiology 59:472-481. IF 2.4.
  • Winstanley, C., Langille, M.G.I., Fothergill, J.L., Kukavica-Ibrulj, I., Paradis-Bleau, C.,  Sanschagrin, F., Thompson, N.R., Winsor, G.L., Quail, M.A., Lennard, N., Bignell, A., Clarke, L., Seeger, K., Saunders, D.,  Harris, D., Parkhill, J., Hancock, R.E.W.*, Brinkman, F.S.L. and Levesque, R.C. (2009).  Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosaGenome Research 19:12-23. IF 13.6.
  • Bronowski, C. and Winstanley, C.* (2009). Identification and distribution of accessory genome DNA sequences from an invasive African isolate of Salmonella Heidelberg .  FEMS Microbiology Letters 298:29-36.  IF 2.0.
  • Winstanley, C.* and Fothergill, J. L. (2009). The role of quorum sensing in chronic cystic fibrosis Pseudomonas aeruginosa infections. FEMS Microbiology Letters 290:1-9.
  • *denotes author for correspondence