In addition, we hold two of the original Rhipicephalus appendiculatus cell lines (RA243 and RA257) established at the London School of Hygiene and Tropical Medicine over 40 years ago by Varma, Pudney and Leake (1975), and two deposits of the RML-15 cell line set up at Rocky Mountain Laboratories, Montana, USA in the late 1970s by Yunker, Cory and Meibos (1985). RML-15 was published as originating from Dermacentor variabilis embryos, but both of our deposits were found to be derived from Rhipicephalus sanguineus; as the exact origin of these cells is unclear and we do not know if they were derived from the same or different primary cultures, for convenience we refer to the low passage deposit as “RML-15” and the high passage deposit as “RML-RSE”. Recent deposits include two new cell lines derived from Brazilian Rhipicephalus microplus (RBME-6, Lima-Duarte et al., 2021) and Amblyomma sculptum (ASE-14, Lima-Duarte et al., 2022).
The table below details the tick and insect cell lines currently available for distribution.
Please email the Tick Cell Biobank for further information on these and other tick cell lines not listed in the table.
Other arthropod cell lines
We currently hold cell lines derived from two midge, two sand fly, two triatomid bug, one honey bee and four mosquito species available for distribution; these are also listed in the table below.
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