Microarrays enable researchers to investigate complex regulatory networks. This has made a significant impact on our understanding of intricate biological processes and diseases.
The CGR, originally the Liverpool Microarray Facility (LMF), has substantial experience and capabilities in the latest array technologies. It can also provide the informatics required to handle the resulting complex data sets. We offer both Affymetrix and Agilent platforms and can generate tailored solutions for our clients.
At the CGR we specialise in expression profiling and offer state-of-the-art array facilities, services and informatics systems, to enable standard as well as tailored solutions.
Current platforms available:
Affymetrix GeneChip® Scanner 3000 7G including the GeneChip® fluidics station and hybridisation oven.
Agilent G2565CA Microarray Scanner including the Agilent SureHyb microarray hybridisation chamber and hybridisation oven.
Fully and semi-customised arrays are also available. The GeneChip Scanner 3000 7G allows scanning of next-generation high-density arrays, including:
- SNP arrays with up to 900,000 SNPs
- tiling arrays
- all exon arrays for whole genome analysis
- whole transcript expression analysis and profiling arrays (e.g. Gene ST and Human Transcriptome Array 2.0)
- miRNA arrays 3’ expression arrays (3’ IVT series).
Fully and semi-customised arrays are also available.
Agilent offer 1,000,000-feature high-density microarrays, enabling both genome-wide and focused studies.
Array options include:
- whole human genome expression arrays
- all exon gene expression arrays
- gene expression arrays for model and non-model organisms
- custom gene expression arrays
- miRNA arrays Comparative Genomic Hybridisation (CGH) arrays (including CGH+SNP and Copy Number Variant (CNV) arrays).
Agilent arrays are offered in a variety of formats and for a wide-range of genomic applications and target species. They can also be customised to individual requirements.