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PRODID:-//University of Liverpool//University Events//EN
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UID:20260416T182223-110300-UniversityOfLiverpool
DTSTAMP:20260416T182223
DTSTART:20250902T130000
DTEND:20250902T140000
LOCATION:Physiology seminar room, 
First floor, Nuffield Wing, 
SUMMARY:Dr Yuewei Xu, XJTLU - 'RNA splicing - gateway to cancer vulnerabilities'
DESCRIPTION:Dr Yuewei Xu is an Assistant Professor at the Academy of Pharmacy, XJTLU, China. He did his undergraduate studies in the Department of Biological Sciences at XJTLU and then obtained an MRes in Cancer Biology and a PhD in Clinical Medicine Research from Imperial College London (supervised by Professor Hector Keun and Dr Anke Nijhuis). He has received multiple awards, including the Imperial-CSC PhD full scholarship and the National Scholarship for undergraduates. He developed a strong interest in RNA splicing during his PhD. The project was to study the role of RNA splicing in ovarian cancer, and he found that targeting RBM39-mediated RNA splicing could overcome PARP inhibitor resistance in vitro and in vivo (Xu et al., 2023, Cell Reports, PMID: 37858464). Now, as a young faculty member at XJTLU, Dr Xu continues his research on RNA splicing in several cancers such as medulloblastoma. He is keen to decipher how RNA splicing may alter cancer cell response to DNA damage and other stresses, and develop novel therapies to combat drug resistance.
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