Dr Camille Bleriot - 'Deciphering the diversity of tumour-associated macrophages in cancer'
2025-01-16 13:00 - 14:00 | Physiology seminar room, Nuffield Wing,
Dr Camille Blériot is an immunologist specialising in macrophage biology, particularly in the contexts of cancer and metabolic disorders. His work focuses on understanding the identity, origin, and function of macrophages across different disease environments. Dr Blériot earned his PhD in biochemistry from the University of Lyon, France, in 2010. His early postdoctoral research at the Institut Pasteur, Paris, under the mentorship of Dr Marc Lecuit, focused on liver macrophages and their interactions with the foodborne pathogen Listeria monocytogenes. This work laid the foundation for his interest in macrophage responses in diverse physiological and pathological settings. In 2016, Dr Blériot relocated to Singapore for a second postdoctoral fellowship in Dr Florent Ginhoux’s laboratory, where he continued his research on liver macrophages. During this period, he explored their developmental origins, heterogeneity, and functions, while also beginning to investigate macrophage roles in tumour microenvironments. In 2020, Dr Blériot returned to France and was appointed a permanent researcher position at the National Center for Scientific Research (CNRS). Dr Blériot now divides his time between the Institut Gustave Roussy (IGR), Europe’s leading cancer research hospital in Villejuif, and the Institut Necker Enfants Malades (INEM) in Paris. At IGR, he continues his work on macrophage involvement in cancer, while at INEM, he focuses on their roles in metabolic diseases. His research employs a combination of murine models, advanced imaging and multi-omics approaches (single-cell RNA sequencing, ATAC sequencing and lipidomics) to unravel the complexity of macrophage biology across diseases.
