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PRODID:-//University of Liverpool//University Events//EN
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UID:20260408T171217-108203-UniversityOfLiverpool
DTSTAMP:20260408T171217
DTSTART:20241014T130000
DTEND:20241014T140000
LOCATION:Lecture Theatre 2, Life Sciences Building, Crown Street, Liverpool, L69
SUMMARY:Professor Tony Hunter - uncovering new cancer mechanisms
DESCRIPTION:'A journey from tyrosine to histidine phosphorylation: uncovering new cancer mechanisms'Professor Tony Hunter, FRSSalk Institute, California, USAHistidine phosphorylation, part of the so-called "hidden phosphoproteome", is a poorly characterised post-translational modification (PTM). Professor Hunter joins us to discuss his team's recent findings which, taken together, suggest that protein-histidine phosphorylation is perturbed in several different human cancer types, affording possible therapeutic opportunities.In 1979, Professor Hunter made his crucial discovery that unchecked tyrosine phosphorylation in cancerous cells was behind their aberrant growth. Today, thanks to his work and that of many others, over 80 tyrosine kinase inhibitors have been approved for clinical use in the treatment of cancer.
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