2011
A Fibronectin-Independent Mechanism of Collagen Fibrillogenesis in Adult Liver Remodeling (Journal article)
Moriya, K., Bae, E., Honda, K., Sakai, K., Sakaguchi, T., Tsujimoto, I., . . . Sakai, T. (2011). A Fibronectin-Independent Mechanism of Collagen Fibrillogenesis in Adult Liver Remodeling. Gastroenterology, 140(5), 1653-1663. doi:10.1053/j.gastro.2011.02.005
DOI: 10.1053/j.gastro.2011.02.005
A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy (Journal article)
Avery, P. J., Jorgensen, A., Hamberg, A., Wadelius, M., Pirmohamed, M., Kamali, F., & Grp, E. U. -P. A. C. T. S. (2011). A Proposal for an Individualized Pharmacogenetics-Based Warfarin Initiation Dose Regimen for Patients Commencing Anticoagulation Therapy. CLINICAL PHARMACOLOGY & THERAPEUTICS, 90(5), 701-706. doi:10.1038/clpt.2011.186
A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC) (Journal article)
Owens, L., Butcher, G., Gilmore, I., Kolamunnage-Dona, R., Oyee, J., Perkins, L., . . . Pirmohamed, M. (2011). A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). BMC PUBLIC HEALTH, 11. doi:10.1186/1471-2458-11-528
A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC) (Journal article)
Owens, L., Butcher, G., Gilmore, I., Kolamunnage-Dona, R., Oyee, J., Perkins, L., . . . Pirmohamed, M. (2011). A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). BMC Public Health, 11, 528.
A systematic review of risk factors for death in adults during and after TB treatment (Journal article)
Waitt, C. J., & Squire, S. B. (2011). A systematic review of risk factors for death in adults during and after TB treatment. International Journal of Tuberculosis and Lung Disease, 15(7), 871-885. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21496360
Adipogenic gene variants in patients with HIV-associated lipodystrophy (Journal article)
Pushpakom, S. P., Owen, A., Vilar, F. J., Castro, H., Dunn, D. T., Back, D. J., & Pirmohamed, M. (2011). Adipogenic gene variants in patients with HIV-associated lipodystrophy. PHARMACOGENETICS AND GENOMICS, 21(2), 76-83. doi:10.1097/FPC.0b013e328342a917
DOI: 10.1097/FPC.0b013e328342a917
Adverse drug reactions causing admission to a paediatric hospital: a pilot study (Journal article)
Gallagher, R. M., Bird, K. A., Mason, J. R., Peak, M., Williamson, P. R., Nunn, A. J., . . . Smyth, R. L. (2011). Adverse drug reactions causing admission to a paediatric hospital: a pilot study. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 36(2), 194-199. doi:10.1111/j.1365-2710.2010.01194.x
DOI: 10.1111/j.1365-2710.2010.01194.x
An Investigation of Disagreement in Causality Assessment of Adverse Drug Reactions (Journal article)
Davies, E. C., Rowe, P. H., James, S., Nickless, G., Ganguli, A., Danjuma, M., . . . Pirmohamed, M. (2011). An Investigation of Disagreement in Causality Assessment of Adverse Drug Reactions. Pharmaceutical Medicine, 25(1), 17-24. doi:10.1007/BF03256843
Animal models for the study of liver fibrosis: new insights from knockout mouse models (Journal article)
Hayashi, H., & Sakai, T. (2011). Animal models for the study of liver fibrosis: new insights from knockout mouse models. American Journal of Physiology-Gastrointestinal and Liver Physiology, 300(5), G729-G738. doi:10.1152/ajpgi.00013.2011
Aspirin resistance: Effect of clinical, biochemical and genetic factors (Journal article)
FitzGerald, R., & Pirmohamed, M. (2011). Aspirin resistance: Effect of clinical, biochemical and genetic factors. PHARMACOLOGY & THERAPEUTICS, 130(2), 213-225. doi:10.1016/j.pharmthera.2011.01.011
DOI: 10.1016/j.pharmthera.2011.01.011
Assessing the safety of stem cell therapeutics (Journal article)
Goldring, C., Duffy, P. A., Benvenisty, N., Andrews, P. W., Ben-David, U., Eakins, R., . . . Park, K. (2011). Assessing the safety of stem cell therapeutics. Cell Stem Cell, 8(6), 618-628.
Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS (Journal article)
Liptrott, N. J., Pushpakom, S., Wyen, C., Faetkenheuer, G., Hoffmann, C., Mauss, S., . . . AIDS, G. C. N. H. I. V. (2012). Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS. PHARMACOGENETICS AND GENOMICS, 22(1), 10-19. doi:10.1097/FPC.0b013e32834dd82e
DOI: 10.1097/FPC.0b013e32834dd82e
Brief Interventions in Dependent Drinkers: A Comparative Prospective Analysis in Two Hospitals (Journal article)
Cobain, K., Owens, L., Kolamunnage-Dona, R., Fitzgerald, R., Gilmore, I., & Pirmohamed, M. (2011). Brief Interventions in Dependent Drinkers: A Comparative Prospective Analysis in Two Hospitals. ALCOHOL AND ALCOHOLISM, 46(4), 434-440. doi:10.1093/alcalc/agr044
Brief interventions in dependent drinkers: A comparative prospective analysis in two hospitals (Journal article)
Cobain, K., Owens, L., Fitzgerald, R., Gilmore, I., & Pirmohamed, M. (2011). Brief interventions in dependent drinkers: A comparative prospective analysis in two hospitals. Alcohol & Alcoholism, 46(6), 434-440.
DOI: 10.1136/gut.2011.239301.219
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology (Journal article)
Eschenhagen, T., Force, T., Ewer, M. S., de Keulenaer, G. W., Suter, T. M., Anker, S. D., . . . Shah, A. M. (2011). Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. EUROPEAN JOURNAL OF HEART FAILURE, 13(1), 1-10. doi:10.1093/eurjhf/hfq213
Changing trends in peptic ulcer disease: the rise of nsaid-induced and fall of h pylori-induced ulcers (Conference Paper)
Musumba, C. O., Van Eker, D., Jorgensen, A., Pritchard, M., & Pirmohamed, M. (2011). CHANGING TRENDS IN PEPTIC ULCER DISEASE: THE RISE OF NSAID-INDUCED AND FALL OF H PYLORI-INDUCED ULCERS. In GUT Vol. 60. doi:10.1136/gut.2011.239301.219
Characterisation and Carriage Ratio of Clostridium difficile Strains Isolated from a Community-Dwelling Elderly Population in the United Kingdom (Journal article)
Miyajima, F., Roberts, P., Swale, A., Price, V., Jones, M., Horan, M., . . . Pirmohamed, M. (2011). Characterisation and Carriage Ratio of Clostridium difficile Strains Isolated from a Community-Dwelling Elderly Population in the United Kingdom. PLOS ONE, 6(8). doi:10.1371/journal.pone.0022804
DOI: 10.1371/journal.pone.0022804
Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury (Journal article)
El-Ghaiesh, S., Sanderson, J. P., Farrell, J., Lavergne, S. N., Syn, W. -K., Pirmohamed, M., . . . Naisbitt, D. J. (2011). Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 128(3), 680-U368. doi:10.1016/j.jaci.2011.04.031
DOI: 10.1016/j.jaci.2011.04.031
Chemotaxis: A Feedback-Based Computational Model Robustly Predicts Multiple Aspects of Real Cell Behaviour (Journal article)
Neilson, M. P., Veltman, D. M., van Haastert, P. J. M., Webb, S. D., Mackenzie, J. A., & Insall, R. H. (2011). Chemotaxis: A Feedback-Based Computational Model Robustly Predicts Multiple Aspects of Real Cell Behaviour. PLoS Biology, 9(5), e1000618. doi:10.1371/journal.pbio.1000618
DOI: 10.1371/journal.pbio.1000618
Chronic inflammation increases hyperpolarization-activated current (Ih) and excitability of C-, but not Aδ-, fiber nociceptors (Journal article)
Weng, X., Smith, M., Sathish, J., & Djouhri, L. (2011). Chronic inflammation increases hyperpolarization-activated current (Ih) and excitability of C-, but not Aδ-, fiber nociceptors. PAIN
Circulating MicroRNAs as Potential Markers of Human Drug-Induced Liver Injury (Journal article)
Lewis, P. J. S., Dear, J., Platt, V., Simpson, K. J., Craig, D. G. N., Antoine, D. J., . . . Park, B. K. (2011). Circulating MicroRNAs as Potential Markers of Human Drug-Induced Liver Injury. HEPATOLOGY, 54(5), 1767-1776. doi:10.1002/hep.24538
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing (Journal article)
Johnson, J. A., Gong, L., Whirl-Carrillo, M., Gage, B. F., Scott, S. A., Stein, C. M., . . . Altman, R. B. (2011). Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing. CLINICAL PHARMACOLOGY & THERAPEUTICS, 90(4), 625-629. doi:10.1038/clpt.2011.185
Complement activation mediated by immune complex formed by Therapeutic Protein and ADA modulates antigen presentation (Journal article)
Sethu, S., Govindappa, K., Pirmohamed, M., Park, K. B., & Sathish, J. G. (2011). Complement activation mediated by immune complex formed by Therapeutic Protein and ADA modulates antigen presentation
Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals (Journal article)
Maeda, T., Sakabe, T., Sunaga, A., Sakai, K., Rivera, A., Keene, D., . . . Sakai, T. (2011). Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals. Current Biology, 21(11), 933-941. doi:10.1016/j.cub.2011.04.007
DOI: 10.1016/j.cub.2011.04.007
Critical Role of Factor XIII in the Initial Stages of Carbon Tetrachloride–Induced Adult Liver Remodeling (Journal article)
Tsujimoto, I., Moriya, K., Sakai, K., Dickneite, G., & Sakai, T. (2011). Critical Role of Factor XIII in the Initial Stages of Carbon Tetrachloride–Induced Adult Liver Remodeling. The American Journal of Pathology, 179(6), 3011-3019. doi:10.1016/j.ajpath.2011.08.037
DOI: 10.1016/j.ajpath.2011.08.037
DABIGATRAN V WARFARIN Authors' reply to Zermansky and Khatib (Journal article)
Hughes, D. A., Pink, J., Lane, S., & Pirmohamed, M. (2011). DABIGATRAN V WARFARIN Authors' reply to Zermansky and Khatib. BRITISH MEDICAL JOURNAL, 343. doi:10.1136/bmj.d7718
Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses (Journal article)
Pink, J., Lane, S., Pirmohamed, M., & Hughes, D. A. (2011). Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses. BRITISH MEDICAL JOURNAL, 343. doi:10.1136/bmj.d6333
Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool (Journal article)
Gallagher, R. M., Kirkham, J. J., Mason, J. R., Bird, K. A., Williamson, P. R., Nunn, A. J., . . . Pirmohamed, M. (2011). Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool. PLOS ONE, 6(12). doi:10.1371/journal.pone.0028096
DOI: 10.1371/journal.pone.0028096
Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)
Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 338(3), 841-849.doi:10.1124/jpet.111.183871
Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)
Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. Journal of Pharmacology and Experimental Therapeutics, 338(3), 841-849. doi:10.1124/jpet.111.183871
Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity (Journal article)
Park, B., Laverty, H., Srivastava, A., Antoine, D., Naisbitt, D., & Williams, D. (2011). Drug bioactivation and protein adduct formation in the pathogenesis of drug-induced toxicity. Chemico-Biological Interactions, 192(1-2), 30-36. doi:10.1016/j.cbi.2010.09.011
DOI: 10.1016/j.cbi.2010.09.011
Drug Induced Hypersensitivity and the HLA Complex (Journal article)
Alfirevic, A., & Pirmohamed, M. (2011). Drug Induced Hypersensitivity and the HLA Complex.. Pharmaceuticals (Basel, Switzerland), 4(1), 69-90. doi:10.3390/ph4010069
Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression (Journal article)
Waitt, C. J., Banda, N. P. K., White, S. A., Kampmann, B., Kumwenda, J., Heyderman, R. S., . . . Squire, S. B. (2011). Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression. JOURNAL OF INFECTIOUS DISEASES, 204(3), 358-362. doi:10.1093/infdis/jir265
Early deaths during TB treatment are associated with depressed innate responses, bacterial infection and TB progression (Journal article)
Waitt, C. J., Banda, N. P. K., White, S. A., Kampmann, B., Kumwenda, J., Heyderman, R. S. H., . . . Squire, S. B. (2011). Early deaths during TB treatment are associated with depressed innate responses, bacterial infection and TB progression. Journal of Infectious Diseases, 204(3), 358-362. Retrieved from http://jid.oxfordjournals.org/content/204/3/358.long
Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis (Journal article)
Elsheikh, A., Castrejon, L., Lavergne, S. N., Whitaker, P., Monshi, M., Callan, H., . . . Naisbitt, D. J. (2011). Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis.. The Journal of allergy and clinical immunology, 127(6), 1543-51.e3. doi:10.1016/j.jaci.2010.12.1119
DOI: 10.1016/j.jaci.2010.12.1119
Establishment of an HLA-typed cohort to elucidate the cellular and chemical basis of drug hypersensitivity reactions (Journal article)
Bell, C., Martinsson, K., Faulkner, L., Alfirevic, A., French, N., Tugwood, J., . . . Park, B. K. (2011). Establishment of an HLA-typed cohort to elucidate the cellular and chemical basis of drug hypersensitivity reactions. TOXICOLOGY, 290(2-3), 132-133. doi:10.1016/j.tox.2011.09.057
DOI: 10.1016/j.tox.2011.09.057
Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis (Journal article)
Uniewicz, K. A., Cross, M. J., & Fernig, D. G. (2011). Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(1), 12-23. doi:10.1074/jbc.M110.190801
Mirza, N., Vasieva, O., Marson, A. G., & Pirmohamed, M. (2011). Exploring the genomic basis of pharmacoresistance in epilepsy: an integrative analysis of large-scale gene expression profiling studies on brain tissue from epilepsy surgery. HUMAN MOLECULAR GENETICS, 20(22), 4381-4394. doi:10.1093/hmg/ddr365
Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction (Journal article)
Pushpakom, S. P., Liptrott, N. J., Rodriguez-Novoa, S., Labarga, P., Soriano, V., Albalater, M., . . . Owen, A. (2011). Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction. JOURNAL OF INFECTIOUS DISEASES, 204(1), 145-153. doi:10.1093/infdis/jir215
Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction (Journal article)
Pushpakom, S. P., Liptrott, N. J., Rodríguez-Nóvoa, S., Labarga, P., Soriano, V., Albalater, M., . . . Owen, A. (2011). Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction. The Journal of Infectious Diseases, 204(1), 145-153. doi:10.1093/infdis/jir215
Genome-wide association study of serious blistering skin rash caused by drugs (Journal article)
Shen, Y., Nicoletti, P., Floratos, A., Pirmohamed, M., Molokhia, M., Geppetti, P., . . . Events, I. S. A. (2012). Genome-wide association study of serious blistering skin rash caused by drugs. PHARMACOGENOMICS JOURNAL, 12(2), 96-104. doi:10.1038/tpj.2010.84
HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans (Journal article)
McCormack, M., Alfirevic, A., Bourgeois, S., Farrell, J. J., Kasperaviciute, D., Carrington, M., . . . Pirmohamed, M. (2011). HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans. NEW ENGLAND JOURNAL OF MEDICINE, 364(12), 1134-1143. doi:10.1056/NEJMoa1013297
Host resistance and coevolution in spatially structured populations (Journal article)
Best, A., Webb, S., White, A., & Boots, M. (2011). Host resistance and coevolution in spatially structured populations. Proceedings of the Royal Society B: Biological Sciences, 278(1715), 2216-2222. doi:10.1098/rspb.2010.1978
How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines? (Journal article)
Laverty, H. G., Benson, C., Cartwright, E. J., Cross, M. J., Garland, C., Hammond, T., . . . Valentin, J. P. (2011). How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?. BRITISH JOURNAL OF PHARMACOLOGY, 163(4), 675-693. doi:10.1111/j.1476-5381.2011.01255.x
DOI: 10.1111/j.1476-5381.2011.01255.x
Hypersensitivity reactions to HIV therapy (Journal article)
Chaponda, M., & Pirmohamed, M. (2011). Hypersensitivity reactions to HIV therapy. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 71(5), 659-671. doi:10.1111/j.1365-2125.2010.03784.x
DOI: 10.1111/j.1365-2125.2010.03784.x
Immune pathomechanism of drug hypersensitivity reactions (Journal article)
Pichler, W. J., Naisbitt, D. J., & Park, B. K. (2011). Immune pathomechanism of drug hypersensitivity reactions. Journal of Allergy and Clinical Immunology, 127(S3), S74-S81.
DOI: 10.1016/j.jaci.2010.11.048
Influence of a functional SCN1A polymorphism on maximum and maintenance doses of antiepileptic drugs in newly diagnosed epilepsy (Conference Paper)
Shazadi, K., Sills, G. J., Pirmohamed, M., & Marson, A. G. (2011). INFLUENCE OF A FUNCTIONAL SCN1A POLYMORPHISM ON MAXIMUM AND MAINTENANCE DOSES OF ANTIEPILEPTIC DRUGS IN NEWLY DIAGNOSED EPILEPSY. In EPILEPSIA Vol. 52 (pp. 91-92). Retrieved from http://gateway.webofknowledge.com/
Investigation into Early Mortality in Malawian Adults treated for Pulmonary Tuberculosis (Thesis / Dissertation)
Waitt, C. (2011). Investigation into Early Mortality in Malawian Adults treated for Pulmonary Tuberculosis. (PhD Thesis, The University of Liverpool).
Lamotrigine is a substrate for OCT1 in brain endothelial cells (Journal article)
Dickens, D., Owen, A., Alfirevic, A., Giannoudis, A., Davies, A., Weksler, B., . . . Pirmohamed, M. (2012). Lamotrigine is a substrate for OCT1 in brain endothelial cells. BIOCHEMICAL PHARMACOLOGY, 83(6), 805-814. doi:10.1016/j.bcp.2011.12.032
DOI: 10.1016/j.bcp.2011.12.032
Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data (Journal article)
van Schie, R. M. F., Wessels, J. A. M., le Cessie, S., de Boer, A., Schalekamp, T., van der Meer, F. J. M., . . . Grp, E. U. -P. A. C. T. S. (2011). Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data. EUROPEAN HEART JOURNAL, 32(15), 1909-1917. doi:10.1093/eurheartj/ehr116
Local transmission processes and disease-driven host extinctions (Journal article)
Best, A., Webb, S., Antonovics, J., & Boots, M. (2012). Local transmission processes and disease-driven host extinctions. Theoretical Ecology, 5(2), 211-217. doi:10.1007/s12080-011-0111-7
DOI: 10.1007/s12080-011-0111-7
Loss of the transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis and intracellular signalling in dendritic cells (Journal article)
Yeang, H. X. A., Hamdam, J. M., Al-Huseini, L. M., Sethu, S., Walsh, J., Kitteringham, N., . . . Sathish, J. G. (2011). Loss of the transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis and intracellular signalling in dendritic cells. Journal of Biological Chemistry
Managing the challenge of chemically reactive metabolites in drug development (Journal article)
Park, B. K., Boobis, A., Clarke, S., Goldring, C. E. P., Jones, D., Kenna, J. G., . . . Baillie, T. A. (2011). Managing the challenge of chemically reactive metabolites in drug development. NATURE REVIEWS DRUG DISCOVERY, 10(4), 292-306. doi:10.1038/nrd3408
Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis (Journal article)
Whitaker, P., Meng, X., Lavergne, S. N., El-Ghaiesh, S., Monshi, M., Earnshaw, C., . . . Park, B. K. (2011). Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis. JOURNAL OF IMMUNOLOGY, 187(1), 200-211. doi:10.4049/jimmunol.1100647
Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis (Journal article)
Whitaker, P., Meng, X., Lavergne, S. N., El-Ghaiesh, S., Monshi, M., Earnshaw, C., . . . Park, B. K. (2011). Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis. J Immunol, 187(1), 200-211. doi:10.4049/jimmunol.1100647
Mdm2 interacts with nme2 (non-metastatic cells 2, protein) and suppresses the ability of nme2 to negatively regulate cell motility (Journal article)
Polanski, R., Maguire, M., Nield, P. C., Jenkins, R. E., Park, B. K., Krawczynska, K., . . . Boyd, M. T. (2011). Mdm2 interacts with nme2 (non-metastatic cells 2, protein) and suppresses the ability of nme2 to negatively regulate cell motility. Carcinogenesis, 32, 1133-1142.
Metabolic acidosis with topiramate and zonisamide (Journal article)
Mirza, N. S., Alfirevic, A., Jorgensen, A., Marson, A. G., & Pirmohamed, M. (2011). Metabolic acidosis with topiramate and zonisamide. Pharmacogenetics and Genomics, 21(5), 297-302. doi:10.1097/FPC.0b013e3283441b95
DOI: 10.1097/FPC.0b013e3283441b95
Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors (Journal article)
Mirza, N. S., Alfirevic, A., Jorgensen, A., Marson, A. G., & Pirmohamed, M. (2011). Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors. PHARMACOGENETICS AND GENOMICS, 21(5), 297-302. doi:10.1097/FPC.0b013e3283441b95
DOI: 10.1097/FPC.0b013e3283441b95
Modeling Cell Movement and Chemotaxis Using Pseudopod-Based Feedback (Journal article)
Neilson, M. P., Mackenzie, J. A., Webb, S. D., & Insall, R. H. (2011). Modeling Cell Movement and Chemotaxis Using Pseudopod-Based Feedback. SIAM Journal on Scientific Computing, 33(3), 1035-1057. doi:10.1137/100788938
Multiple drug hypersensitivity: role of T regulatory cells (Conference Paper)
Daubner, B., Groux-Keller, M., Kawabata, T., Naisbitt, D. J., Park, K. B., Thomas, W., . . . Pichler, W. J. (2011). Multiple drug hypersensitivity: role of T regulatory cells. In JOURNAL OF IMMUNOLOGY Vol. 186. Retrieved from http://gateway.webofknowledge.com/
Musculoskeletal diseases--tendon (Journal article)
Sakabe, T., & Sakai, T. (2011). Musculoskeletal diseases--tendon.. British medical bulletin, 99, 211-225.
Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy (Journal article)
Lister, A., Nedjadi, T., Kitteringham, N. R., Campbell, F., Costello, E., Lloyd, B., . . . Park, B. K. (2011). Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. MOLECULAR CANCER, 10. doi:10.1186/1476-4598-10-37
Novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3 (Journal article)
Bone, T., & Goldring, C. (2011). Novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J. Cell Science, In press.
Pharmacogenetics of adverse drug reactions (Chapter)
Pushpakom, S., & Pirmohamed, M. (2011). Pharmacogenetics of adverse drug reactions. In J. Talbott, & P. Waller (Eds.), Stephens' Detection of New Adverse Drug Reactions (pp. Not known). Malden, MA, USA: John Wiley & Sons.
Pharmacogenetics: past, present and future (Journal article)
Pirmohamed, M. (2011). Pharmacogenetics: past, present and future. DRUG DISCOVERY TODAY, 16(19-20), 852-861. doi:10.1016/j.drudis.2011.08.006
DOI: 10.1016/j.drudis.2011.08.006
Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing (Journal article)
Wadelius, M., & Alfirevic, A. (2011). Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing. Genome Medicine, 3(12), 78.
Pharmacogenomics in neurology: Current state and future steps (Journal article)
Chan, A., Pirmohamed, M., & Comabella, M. (2011). Pharmacogenomics in neurology: Current state and future steps. ANNALS OF NEUROLOGY, 70(5), 684-697. doi:10.1002/ana.22502
Phenotype Standardization for Immune-Mediated Drug-Induced Skin Injury (Journal article)
Pirmohamed, M., Friedmann, P. S., Molokhia, M., Loke, Y. K., Smith, C., Phillips, E., . . . Shear, N. H. (2011). Phenotype Standardization for Immune-Mediated Drug-Induced Skin Injury. CLINICAL PHARMACOLOGY & THERAPEUTICS, 89(6), 896-901. doi:10.1038/clpt.2011.79
Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics (Journal article)
Becquemont, L., Alfirevic, A., Amstutz, U., Brauch, H., Jacqz-Aigrain, E., Laurent-Puig, P., . . . Daly, A. K. (2011). Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics. Pharmacogenomics, 12(1), 113-124.
Prescribing in liver disease (Journal article)
Pirmohamed, M. (2011). Prescribing in liver disease. Medicine, 39(9), 541-544. doi:10.1016/j.mpmed.2011.06.009
DOI: 10.1016/j.mpmed.2011.06.009
van Staa, T. -P., Goldacre, B., Gulliford, M., Cassell, J., Pirmohamed, M., Taweel, A., . . . Smeeth, L. (2011). Randomised Evaluations of Accepted Choices in Treatment (REACT) trials: large-scale pragmatic trials within databases of routinely collected electronic healthcare records.. Trials, 12(Suppl 1), A104. doi:10.1186/1745-6215-12-S1-A104
DOI: 10.1186/1745-6215-12-S1-A104
Report on the 8th Annual Cold Spring Harbor/Wellcome Trust meeting on Pharmacogenomics and Personalized Medicine (Journal article)
Carr, D. F., & Alfirevic, A. (2011). Report on the 8th Annual Cold Spring Harbor/Wellcome Trust meeting on Pharmacogenomics and Personalized Medicine.. Pharmacogenomics, 12(3), 315-317. doi:10.2217/pgs.10.217
Risk modeling strategies for pharmacogenetic studies (Journal article)
Jorgensen, A. L., & Pirmohamed, M. (2011). Risk modeling strategies for pharmacogenetic studies. PHARMACOGENOMICS, 12(3), 397-410. doi:10.2217/PGS.10.198
Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury (Journal article)
Williams, C. D., Antoine, D. J., Shaw, P. J., Benson, C., Farhood, A., Williams, D. P., . . . Jaeschke, H. (2011). Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury. Toxicol Appl Pharmacol, 252(3), 289-297.
The effect of landscape heterogeneity and host movement on a tick-borne pathogen (Journal article)
Jones, E. O., Webb, S. D., Ruiz-Fons, F. J., Albon, S., & Gilbert, L. (2011). The effect of landscape heterogeneity and host movement on a tick-borne pathogen. Theoretical Ecology, 4(4), 435-448. doi:10.1007/s12080-010-0087-8
DOI: 10.1007/s12080-010-0087-8
The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo (Journal article)
Priestley, C. C., Regan, S., Park, K. B., & Williams, D. P. (2011). The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo.. Toxicology, E-pub.
The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials (Journal article)
Mercer, A. E., Copple, I. M., Maggs, J. L., O'Neill, P. M., & Park, B. K. (2011). The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(2), 987-996. doi:10.1074/jbc.M110.144188
STAtin-Induced Muscle Toxicity: Exploration Using the UK GEneral Practice Research Database - Recruitment (Conference Paper)
Campbell, J., van Staa, T. P., McCann, G., O'Meara, H., & Pirmohamed, M. (2011). STAtin-Induced Muscle Toxicity: Exploration Using the UK GEneral Practice Research Database - Recruitment. In PHARMACOEPIDEMIOLOGY AND DRUG SAFETY Vol. 20 (pp. S183). Retrieved from http://gateway.webofknowledge.com/
Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles (Journal article)
Lucena, M. I., Molokhia, M., Shen, Y., Urban, T. J., Aithal, G. P., Andrade, R. J., . . . SAEC, I. (2011). Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles. GASTROENTEROLOGY, 141(1), 338-347. doi:10.1053/j.gastro.2011.04.001
DOI: 10.1053/j.gastro.2011.04.001
Tetracycline-inducible protein expression in pancreatic cancer cells: effects of CapG overexpression (Journal article)
Tonack, S., Patel, S., Jalali, M., Nedjadi, T., Jenkins, R. E., Goldring, C., . . . Costello, E. (2011). Tetracycline-inducible protein expression in pancreatic cancer cells: effects of CapG overexpression.. World journal of gastroenterology, 17(15), 1947-1960. doi:10.3748/wjg.v17.i15.1947
The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein (Journal article)
Vogler, M., Dickens, D., Dyer, M. J. S., Owen, A., Pirmohamed, M., & Cohen, G. M. (2011). The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 408(2), 344-349. doi:10.1016/j.bbrc.2011.04.043
DOI: 10.1016/j.bbrc.2011.04.043
The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1 (Journal article)
Carrol, E. D., Payton, A., Payne, D., Miyajima, F., Chaponda, M., Mankhambo, L. A., . . . Ollier, W. E. (2011). The IL1RN Promoter rs4251961 Correlates with IL-1 Receptor Antagonist Concentrations in Human Infection and Is Differentially Regulated by GATA-1. JOURNAL OF IMMUNOLOGY, 186(4), 2329-2335. doi:10.4049/jimmunol.1002402
The pharmacokinetic evaluation of artemisinin drugs for the treatment of malaria in paediatric populations (Journal article)
Mercer, A. E., & Sallah, M. S. (2011). The pharmacokinetic evaluation of artemisinin drugs for the treatment of malaria in paediatric populations. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 7(4), 427-439. doi:10.1517/17425255.2011.557064
DOI: 10.1517/17425255.2011.557064
The Phenotype Standardization Project: Improving Pharmacogenetic Studies of Serious Adverse Drug Reactions (Journal article)
Pirmohamed, M., Aithal, G. P., Behr, E., Daly, A., & Roden, D. (2011). The Phenotype Standardization Project: Improving Pharmacogenetic Studies of Serious Adverse Drug Reactions. CLINICAL PHARMACOLOGY & THERAPEUTICS, 89(6), 784-785. doi:10.1038/clpt.2011.30
The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors (Journal article)
Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., . . . Pirmohamed, M. (2012). The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 73(1), 66-76. doi:10.1111/j.1365-2125.2011.04051.x
DOI: 10.1111/j.1365-2125.2011.04051.x
Trimethoprim Stimulates T-Cells through Metabolism-Dependent and -Independent Pathways (Journal article)
El-Ghaiesh, S., Sanderson, J. P., Farrell, J., Lavergne, S. N., Syn, W. -K., Pirmohamed, M., . . . Naisbitt, D. J. (2011). Trimethoprim Stimulates T-Cells through Metabolism-Dependent and -Independent Pathways. CHEMICAL RESEARCH IN TOXICOLOGY, 24(6), 791-793. doi:10.1021/tx2001256
Validation of the Australian five-SNP genetic classifier of early treatment outcomes in newly diagnosed epilepsy (Conference Paper)
Sills, G., Shazadi, K., Petrovski, S., O'Brien, T., Pirmohamed, M., & Marson, A. (2011). VALIDATION OF THE AUSTRALIAN FIVE-SNP GENETIC CLASSIFIER OF EARLY TREATMENT OUTCOMES IN NEWLY DIAGNOSED EPILEPSY. In EPILEPSIA Vol. 52 (pp. 92). Retrieved from http://gateway.webofknowledge.com/