Photo of Dr Andrew Stachulski

Dr Andrew Stachulski

Research Fellow Chemistry

    Publications

    2021

    Synthesis and toxicity profile in 293 human embryonic kidney cells of the beta D-glucuronide derivatives of ortho-, meta- and para-cresol (Journal article)

    London, J. A., Wang, E. C. S., Barsukov, I. L., Yates, E. A., & Stachulski, A. V. (2021). Synthesis and toxicity profile in 293 human embryonic kidney cells of the beta D-glucuronide derivatives of ortho-, meta- and para-cresol. CARBOHYDRATE RESEARCH, 499. doi:10.1016/j.carres.2020.108225

    DOI: 10.1016/j.carres.2020.108225

    2020

    Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2? (Journal article)

    Stachulski, A. V., Taujanskas, J., Pate, S. L., Rajoli, R. K. R., Aljayyoussi, G., Pennington, S. H., . . . O'Neill, P. M. (2020). Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?. ACS infectious diseases. doi:10.1021/acsinfecdis.0c00478

    DOI: 10.1021/acsinfecdis.0c00478

    Acyl glucuronide reactivity in perspective (Journal article)

    Bradshaw, P. R., Athersuch, T. J., Stachulski, A. V., & Wilson, I. D. (2020). Acyl glucuronide reactivity in perspective. DRUG DISCOVERY TODAY, 25(9), 1639-1650. doi:10.1016/j.drudis.2020.07.009

    DOI: 10.1016/j.drudis.2020.07.009

    Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships. (Journal article)

    Bradshaw, P. R., Richards, S. E., Wilson, I. D., Stachulski, A. V., Lindon, J. C., & Athersuch, T. J. (2020). Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships.. Organic & biomolecular chemistry. doi:10.1039/c9ob02008j

    DOI: 10.1039/c9ob02008j

    2019

    Synthesis of MeBmt and related derivatives via syn-selective ATH-DKR (Journal article)

    Rolt, A., O'Neill, P. M., Liang, T. J., & Stachulski, A. V. (2019). Synthesis of MeBmt and related derivatives via syn-selective ATH-DKR. RSC ADVANCES, 9(69), 40336-40339. doi:10.1039/c9ra08256e

    DOI: 10.1039/c9ra08256e

    2018

    Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus (Journal article)

    Stachulski, A. V., Santoro, M. G., Piacentini, S., Belardo, G., La Frazia, S., Pidathala, C., . . . Rossignol, J. -F. (2018). Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus. FUTURE MEDICINAL CHEMISTRY, 10(8), 851-862. doi:10.4155/fmc-2017-0217

    DOI: 10.4155/fmc-2017-0217

    2017

    Rational Design, Synthesis and Biological Evaluation of Heterocyclic Quinolones Targeting the respiratory chain of Mycobacterium tuberculosis. (Journal article)

    Hong, W. D., Gibbons, P. D., Leung, S. C., Amewu, R., Stocks, P. A., Stachulski, A. V., . . . Nixon, G. L. (2017). Rational Design, Synthesis and Biological Evaluation of Heterocyclic Quinolones Targeting the respiratory chain of Mycobacterium tuberculosis.. Journal of medicinal chemistry, 60(9), 3703-3726. doi:10.1021/acs.jmedchem.6b01718

    DOI: 10.1021/acs.jmedchem.6b01718

    Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs (Journal article)

    Stachulski, A. V., Swift, K., Cooper, M., Reynolds, S., Norton, D., Slonecker, S. D., & Rossignol, J. -F. (2017). Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 126, 154-159. doi:10.1016/j.ejmech.2016.09.080

    DOI: 10.1016/j.ejmech.2016.09.080

    2014

    Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein (Journal article)

    Monrad, R. N., Errey, J. C., Barry, C. S., Iqbal, M., Meng, X., Iddon, L., . . . Davis, B. G. (2014). Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein. CHEMICAL SCIENCE, 5(10), 3789-3794. doi:10.1039/c4sc01329h

    DOI: 10.1039/c4sc01329h

    Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients (Journal article)

    Hammond, T. G., Meng, X., Jenkins, R. E., Maggs, J. L., Castelazo, A. S., Regan, S. L., . . . Williams, D. P. (2014). Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 350(2), 387-402. doi:10.1124/jpet.114.215079

    DOI: 10.1124/jpet.114.215079

    2013

    Convenient syntheses of halo-dibenz[b,f]azepines and carbamazepine analogues via N-arylindoles. (Journal article)

    Elliott, E. -C., Maggs, J. L., Park, B. K., O'Neill, P. M., & Stachulski, A. V. (2013). Convenient syntheses of halo-dibenz[b,f]azepines and carbamazepine analogues via N-arylindoles.. Organic & biomolecular chemistry, 11(48), 8426-8434. doi:10.1039/c3ob41252k

    DOI: 10.1039/c3ob41252k

    The Generation, Detection, and Effects of Reactive Drug Metabolites (Journal article)

    Stachulski, A. V., Baillie, T. A., Park, B. K., Obach, R. S., Dalvie, D. K., Williams, D. P., . . . Lennard, M. S. (2013). The Generation, Detection, and Effects of Reactive Drug Metabolites. MEDICINAL RESEARCH REVIEWS, 33(5), 985-1080. doi:10.1002/med.21273

    DOI: 10.1002/med.21273

    Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides. (Journal article)

    Stachulski, A. V., & Meng, X. (2013). Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides.. Natural product reports, 30(6), 806-848. doi:10.1039/c3np70003h

    DOI: 10.1039/c3np70003h

    Activation of carbamazepine-responsive T-cell clones with metabolically inert halogenated derivatives (Journal article)

    Farrell, J., Lichtenfels, M., Sullivan, A., Elliott, E. C., Alfirevic, A., Stachulski, A. V., . . . Park, B. K. (2013). Activation of carbamazepine-responsive T-cell clones with metabolically inert halogenated derivatives. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 132(2), 493-495. doi:10.1016/j.jaci.2013.02.045

    DOI: 10.1016/j.jaci.2013.02.045

    2012

    Haloarene Derivatives of Carbamazepine with Reduced Bioactivation Liabilities: 2-Monohalo and 2,8-Dihalo Derivatives (Journal article)

    Elliott, E. -C., Regan, S. L., Maggs, J. L., Bowkett, E. R., Parry, L. J., Williams, D. P., . . . Stachulski, A. V. (2012). Haloarene Derivatives of Carbamazepine with Reduced Bioactivation Liabilities: 2-Monohalo and 2,8-Dihalo Derivatives. JOURNAL OF MEDICINAL CHEMISTRY, 55(22), 9773-9784. doi:10.1021/jm301013n

    DOI: 10.1021/jm301013n

    2011

    Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication (Journal article)

    Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Lawrenson, A. S., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication. JOURNAL OF MEDICINAL CHEMISTRY, 54(24), 8670-8680. doi:10.1021/jm201264t

    DOI: 10.1021/jm201264t

    Convenient syntheses of benzo-fluorinated dibenz[b,f]azepines: rearrangements of isatins, acridines, and indoles. (Journal article)

    Elliott, E. -C., Bowkett, E. R., Maggs, J. L., Bacsa, J., Park, B. K., Regan, S. L., . . . Stachulski, A. V. (2011). Convenient syntheses of benzo-fluorinated dibenz[b,f]azepines: rearrangements of isatins, acridines, and indoles.. Organic letters, 13(20), 5592-5595. doi:10.1021/ol202318w

    DOI: 10.1021/ol202318w

    Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)

    Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. Journal of Pharmacology and Experimental Therapeutics, 338(3), 841-849. doi:10.1124/jpet.111.183871

    DOI: 10.1124/jpet.111.183871

    Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients (Journal article)

    Meng, X., Jenkins, R. E., Berry, N. G., Maggs, J. L., Farrell, J., Lane, C. S., . . . Park, B. K. (2011). Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 338(3), 841-849. doi:10.1124/jpet.111.183871

    DOI: 10.1124/jpet.111.183871

    Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication (Journal article)

    Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Iqbal, M., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication. JOURNAL OF MEDICINAL CHEMISTRY, 54(12), 4119-4132. doi:10.1021/jm200153p

    DOI: 10.1021/jm200153p

    Chemistry and reactivity of acyl glucuronides. (Journal article)

    Stachulski, A. V. (2011). Chemistry and reactivity of acyl glucuronides.. Current drug metabolism, 12(3), 215-221. doi:10.2174/138920011795101822

    DOI: 10.2174/138920011795101822

    Recent Drug Discovery against Cryptosporidium (Chapter)

    Rossignol, J. -F., Semple, J. E., Stachulski, A. V., & Gargala, G. (n.d.). Recent Drug Discovery against Cryptosporidium. In Apicomplexan Parasites (pp. 493-512). Wiley-VCH Verlag GmbH & Co. KGaA. doi:10.1002/9783527633883.ch27

    DOI: 10.1002/9783527633883.ch27

    Synthesis of a series of phenylacetic acid 1-ß-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides. (Journal article)

    Iddon, L., Richards, S. E., Johnson, C. H., Harding, J. R., Wilson, I. D., Nicholson, J. K., . . . Stachulski, A. V. (2011). Synthesis of a series of phenylacetic acid 1-ß-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides.. Organic & biomolecular chemistry, 9(3), 926-934. doi:10.1039/c0ob00820f

    DOI: 10.1039/c0ob00820f

    Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication (Journal article)

    Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Iqbal, M., . . . Rossignol, J. -F. (2011). Thiazolides as Novel Antiviral Agents. 1. Inhibition of Hepatitis B Virus Replication. Journal of Medicinal Chemistry,, 54, 4119-4132.

    2010

    High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma. (Journal article)

    Karlsson, E. S., Johnson, C. H., Sarda, S., Iddon, L., Iqbal, M., Meng, X., . . . Lindon, J. C. (2010). High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma.. Rapid communications in mass spectrometry : RCM, 24(20), 3043-3051. doi:10.1002/rcm.4740

    DOI: 10.1002/rcm.4740

    Corrigendum to “Syntheses of structurally diverse amino acids, including d-hydroxylysine, using the acyl nitroso Diels–Alder reaction” [Tetrahedron Lett. 51 (2010) 2160] (Journal article)

    Bollans, L., Bacsa, J., O’Farrell, D. J., Waterson, S., & Stachulski, A. V. (2010). Corrigendum to “Syntheses of structurally diverse amino acids, including d-hydroxylysine, using the acyl nitroso Diels–Alder reaction” [Tetrahedron Lett. 51 (2010) 2160]. Tetrahedron Letters, 51(23), 3159. doi:10.1016/j.tetlet.2010.04.058

    DOI: 10.1016/j.tetlet.2010.04.058

    Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols (Journal article)

    Amewu, R., Gibbons, P., Mukhtar, A., Stachulski, A. V., Ward, S. A., Hall, C., . . . O'Neill, P. M. (2010). Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols. ORGANIC & BIOMOLECULAR CHEMISTRY, 8(9), 2068-2077. doi:10.1039/b924319d

    DOI: 10.1039/b924319d

    Syntheses of structurally diverse amino acids, including d-hydroxylysine, using the acyl nitroso Diels–Alder reaction (Journal article)

    Bollans, L., Bacsa, J., O’Farrell, D. A., Waterson, S., & Stachulski, A. V. (2010). Syntheses of structurally diverse amino acids, including d-hydroxylysine, using the acyl nitroso Diels–Alder reaction. Tetrahedron Letters, 51(16), 2160-2163. doi:10.1016/j.tetlet.2010.02.076

    DOI: 10.1016/j.tetlet.2010.02.076

    Evaluation of new thiazolide/thiadiazolide derivatives reveals nitro group-independent efficacy against in vitro development of Cryptosporidium parvum. (Journal article)

    Gargala, G., Le Goff, L., Ballet, J. -J., Favennec, L., Stachulski, A. V., & Rossignol, J. -F. (2010). Evaluation of new thiazolide/thiadiazolide derivatives reveals nitro group-independent efficacy against in vitro development of Cryptosporidium parvum.. Antimicrobial agents and chemotherapy, 54(3), 1315-1318. doi:10.1128/aac.00614-09

    DOI: 10.1128/aac.00614-09

    Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin. (Journal article)

    Pacorel, B., Leung, S. C., Stachulski, A. V., Davies, J., Vivas, L., Lander, H., . . . O'Neill, P. M. (2010). Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.. Journal of medicinal chemistry, 53(2), 633-640. doi:10.1021/jm901216v

    DOI: 10.1021/jm901216v

    A convenient new synthesis of quaternary ammonium glucuronides of drug molecules (Journal article)

    Iddon, L., Bragg, R. A., Harding, J. R., & Stachulski, A. V. (2010). A convenient new synthesis of quaternary ammonium glucuronides of drug molecules. Tetrahedron, 66(2), 537-541. doi:10.1016/j.tet.2009.10.113

    DOI: 10.1016/j.tet.2009.10.113

    Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides. (Journal article)

    Johnson, C. H., Karlsson, E., Sarda, S., Iddon, L., Iqbal, M., Meng, X., . . . Lindon, J. C. (2010). Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.. Xenobiotica; the fate of foreign compounds in biological systems, 40(1), 9-23. doi:10.3109/00498250903348720

    DOI: 10.3109/00498250903348720

    2009

    Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases. (Journal article)

    Heyes, D. J., Levy, C., Lafite, P., Roberts, I. S., Goldrick, M., Stachulski, A. V., . . . Leys, D. (2009). Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases.. The Journal of biological chemistry, 284(51), 35514-35523. doi:10.1074/jbc.m109.056630

    DOI: 10.1074/jbc.m109.056630

    The acyl nitroso Diels-Alder (ANDA) reaction of sorbate derivatives: an X-ray and N-15 NMR study with an application to amino-acid synthesis (Journal article)

    Bollans, L., Bacsa, J., Iggo, J. A., Morris, G. A., & Stachulski, A. V. (2009). The acyl nitroso Diels-Alder (ANDA) reaction of sorbate derivatives: an X-ray and N-15 NMR study with an application to amino-acid synthesis. ORGANIC & BIOMOLECULAR CHEMISTRY, 7(21), 4531-4538. doi:10.1039/b912963d

    DOI: 10.1039/b912963d

    Convenient syntheses of the in vivo carbohydrate metabolites of mycophenolic acid: reactivity of the acyl glucuronide (Journal article)

    Jones, A. E., Wilson, H. K., Meath, P., Meng, X., Holt, D. W., Johnston, A., . . . Stachulski, A. V. (2009). Convenient syntheses of the in vivo carbohydrate metabolites of mycophenolic acid: reactivity of the acyl glucuronide. Tetrahedron Letters, 50(35), 4973-4977. doi:10.1016/j.tetlet.2009.06.060

    DOI: 10.1016/j.tetlet.2009.06.060

    Syntheses and structures of anomeric quaternary ammonium ß-glucosides and comments on the anomeric C–N bond lengths (Journal article)

    Iddon, L., Bragg, R. A., Harding, J. R., Pidathala, C., Bacsa, J., Kirby, A. J., & Stachulski, A. V. (2009). Syntheses and structures of anomeric quaternary ammonium ß-glucosides and comments on the anomeric C–N bond lengths. Tetrahedron, 65(32), 6396-6402. doi:10.1016/j.tet.2009.05.086

    DOI: 10.1016/j.tet.2009.05.086

    Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1 beta-O-acyl glucuronides (Journal article)

    Berry, N. G., Iddon, L., Iqbal, M., Meng, X., Jayapal, P., Johnson, C. H., . . . Stachulski, A. V. (2009). Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1 beta-O-acyl glucuronides. ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2525-2533. doi:10.1039/b822777b

    DOI: 10.1039/b822777b

    In vitro efficacy of nitro- and halogeno-thiazolide/thiadiazolide derivatives against Sarcocystis neurona. (Journal article)

    Gargala, G., Le Goff, L., Ballet, J. J., Favennec, L., Stachulski, A. V., & Rossignol, J. F. (2009). In vitro efficacy of nitro- and halogeno-thiazolide/thiadiazolide derivatives against Sarcocystis neurona.. Veterinary parasitology, 162(3-4), 230-235. doi:10.1016/j.vetpar.2009.03.022

    DOI: 10.1016/j.vetpar.2009.03.022

    2008

    Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. (Journal article)

    Johnson, C. H., Athersuch, T. J., Wilson, I. D., Iddon, L., Meng, X., Stachulski, A. V., . . . Nicholson, J. K. (2008). Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions.. Analytical chemistry, 80(13), 4886-4895. doi:10.1021/ac702614t

    DOI: 10.1021/ac702614t

    2007

    NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues. (Journal article)

    Johnson, C. H., Wilson, I. D., Harding, J. R., Stachulski, A. V., Iddon, L., Nicholson, J. K., & Lindon, J. C. (2007). NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues.. Analytical chemistry, 79(22), 8720-8727. doi:10.1021/ac071368i

    DOI: 10.1021/ac071368i

    Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis. (Journal article)

    Meng, X., Maggs, J. L., Pryde, D. C., Planken, S., Jenkins, R. E., Peakman, T. M., . . . Stachulski, A. V. (2007). Cyclization of the acyl glucuronide metabolite of a neutral endopeptidase inhibitor to an electrophilic glutarimide: synthesis, reactivity, and mechanistic analysis.. Journal of medicinal chemistry, 50(24), 6165-6176. doi:10.1021/jm0706766

    DOI: 10.1021/jm0706766

    Efficient synthesis of 1ß-O-acyl glucuronides via selective acylation of allyl or benzyl d-glucuronate (Journal article)

    Bowkett, E. R., Harding, J. R., Maggs, J. L., Park, B. K., Perrie, J. A., & Stachulski, A. V. (2007). Efficient synthesis of 1ß-O-acyl glucuronides via selective acylation of allyl or benzyl d-glucuronate. Tetrahedron, 63(32), 7596-7605. doi:10.1016/j.tet.2007.05.050

    DOI: 10.1016/j.tet.2007.05.050

    Convenient syntheses of deoxypyranose sugars from glucuronolactone (Journal article)

    Stanford (nee Sinnott), D., & Stachulski, A. V. (2007). Convenient syntheses of deoxypyranose sugars from glucuronolactone. Tetrahedron Letters, 48(13), 2361-2364. doi:10.1016/j.tetlet.2007.01.127

    DOI: 10.1016/j.tetlet.2007.01.127

    Back matter (Journal article)

    Back matter (2007). Organic & Biomolecular Chemistry, 5(4), 708. doi:10.1039/b701157c

    DOI: 10.1039/b701157c

    Investigation of the immunogenicity of diclofenac and diclofenac metabolites (Journal article)

    Naisbitt, D. J., Sanderson, L. S., Meng, X., Stachulski, A. V., Clarke, S. E., & Park, B. K. (2007). Investigation of the immunogenicity of diclofenac and diclofenac metabolites. TOXICOLOGY LETTERS, 168(1), 45-50. doi:10.1016/j.toxlet.2006.10.014

    DOI: 10.1016/j.toxlet.2006.10.014

    The chemistry and biological activity of acyl glucuronides. (Journal article)

    Stachulski, A. V. (2007). The chemistry and biological activity of acyl glucuronides.. Current opinion in drug discovery & development, 10(1), 58-66.

    2006

    Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin (Journal article)

    Amewu, R., Stachulski, A. V., Ward, S. A., Berry, N. G., Bray, P. G., Davies, J., . . . O'Neill, P. M. (2006). Design and synthesis of orally active dispiro 1,2,4,5-tetraoxanes; synthetic antimalarials with superior activity to artemisinin. ORGANIC & BIOMOLECULAR CHEMISTRY, 4(24), 4431-4436. doi:10.1039/b613565j

    DOI: 10.1039/b613565j

    Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology (Journal article)

    Amewu, R., Stachulski, A. V., Berry, N. G., Ward, S. A., Davies, J., Labat, G., . . . O'Neill, P. M. (2006). Synthesis of 1,2,4-trioxepanes via application of thiol-olefin Co-oxygenation methodology. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(23), 6124-6130. doi:10.1016/j.bmcl.2006.08.098

    DOI: 10.1016/j.bmcl.2006.08.098

    Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis. (Journal article)

    Stachulski, A. V., Harding, J. R., Lindon, J. C., Maggs, J. L., Park, B. K., & Wilson, I. D. (2006). Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis.. Journal of medicinal chemistry, 49(24), 6931-6945. doi:10.1021/jm060599z

    DOI: 10.1021/jm060599z

    Activation of T cells by carbamazepine and carbamazepine metabolites (Journal article)

    Wu, Y., Sanderson, J. P., Farrell, J., Drummond, N. S., Hanson, A., Bowkett, E., . . . Naisbitt, D. J. (2006). Activation of T cells by carbamazepine and carbamazepine metabolites. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 118(1), 233-241. doi:10.1016/j.jaci.2006.03.005

    DOI: 10.1016/j.jaci.2006.03.005

    Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4. (Journal article)

    Row, E. C., Brown, S. A., Stachulski, A. V., & Lennard, M. S. (2006). Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4.. Bioorganic & medicinal chemistry, 14(11), 3865-3871. doi:10.1016/j.bmc.2006.01.046

    DOI: 10.1016/j.bmc.2006.01.046

    Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4. (Journal article)

    Row, E. C., Brown, S. A., Stachulski, A. V., & Lennard, M. S. (2006). Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4.. Organic & biomolecular chemistry, 4(8), 1604-1610. doi:10.1039/b601096b

    DOI: 10.1039/b601096b

    Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo (Journal article)

    Stachulski, A. V., Berry, N. G., Low, A. C. L., Moores, S. L., Row, E., Warhurst, D. C., . . . Rossignol, J. F. (2006). Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. JOURNAL OF MEDICINAL CHEMISTRY, 49(4), 1450-1454. doi:10.1021/jm050973f

    DOI: 10.1021/jm050973f

    Development of novel furanocoumarin dimers as potent and selective inhibitors of CYP3A4. (Journal article)

    Row, E., Brown, S. A., Stachulski, A. V., & Lennard, M. S. (2006). Development of novel furanocoumarin dimers as potent and selective inhibitors of CYP3A4.. Drug metabolism and disposition: the biological fate of chemicals, 34(2), 324-330. doi:10.1124/dmd.105.007294

    DOI: 10.1124/dmd.105.007294

    Corrigendum to “New stable anomeric hydroperoxides derived from 2-deoxy-sugars; enantioselective epoxidation of 2-methyl-1,4-naphthoquinone” (Journal article)

    Kosnik, W., Stachulski, A. V., & Chmielewski, M. (2006). Corrigendum to “New stable anomeric hydroperoxides derived from 2-deoxy-sugars; enantioselective epoxidation of 2-methyl-1,4-naphthoquinone”. Tetrahedron: Asymmetry, 17(2), 313. doi:10.1016/j.tetasy.2005.12.002

    DOI: 10.1016/j.tetasy.2005.12.002

    2005

    In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group (Journal article)

    Esposito, M., Stettler, R., Moores, S. L., Pidathala, C., Muller, N., Stachulski, A., . . . Hemphill, A. (2005). In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 49(9), 3715-3723. doi:10.1128/AAC.49.9.3715-3723.2005

    DOI: 10.1128/AAC.49.9.3715-3723.2005

    Effective synthesis of 1beta-acyl glucuronides by selective acylation. (Journal article)

    Perrie, J. A., Harding, J. R., Holt, D. W., Johnston, A., Meath, P., & Stachulski, A. V. (2005). Effective synthesis of 1beta-acyl glucuronides by selective acylation.. Organic letters, 7(13), 2591-2594. doi:10.1021/ol0507165

    DOI: 10.1021/ol0507165

    New stable anomeric hydroperoxides derived from 2-deoxysugars; enantioselective epoxidation of 2-methyl-1,4-naphthoquinone (Journal article)

    Kosnik, W., Stachulski, A. V., & Chmielewski, M. (2005). New stable anomeric hydroperoxides derived from 2-deoxysugars; enantioselective epoxidation of 2-methyl-1,4-naphthoquinone. Tetrahedron: Asymmetry, 16(11), 1975-1981. doi:10.1016/j.tetasy.2005.04.009

    DOI: 10.1016/j.tetasy.2005.04.009

    Glucuronidation of steroidal alcohols using iodosugar and imidate donors. (Journal article)

    Harding, J. R., King, C. D., Perrie, J. A., Sinnott, D., & Stachulski, A. V. (2005). Glucuronidation of steroidal alcohols using iodosugar and imidate donors.. Organic & biomolecular chemistry, 3(8), 1501-1507. doi:10.1039/b412217h

    DOI: 10.1039/b412217h

    The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones (Journal article)

    Bundu, A., Berry, N. G., Gill, C. D., Dxyer, C. L., Stachulski, A. V., Taylor, R. J. K., & Whittall, J. (2005). The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones. TETRAHEDRON-ASYMMETRY, 16(1), 283-293. doi:10.1016/j.tetasy.2004.11.015

    DOI: 10.1016/j.tetasy.2004.11.015

    2004

    Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac. (Journal article)

    Kenny, J. R., Maggs, J. L., Meng, X., Sinnott, D., Clarke, S. E., Park, B. K., & Stachulski, A. V. (2004). Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.. Journal of medicinal chemistry, 47(11), 2816-2825. doi:10.1021/jm030891w

    DOI: 10.1021/jm030891w

    An unsaturated peptidomimetic assembly derived from a carbohydrate. (Journal article)

    Chung, Y. -K., Claridge, T. D. W., Fleet, G. W. J., Johnson, S. W., Jones, J. H., Lumbard, K. W., & Stachulski, A. V. (2004). An unsaturated peptidomimetic assembly derived from a carbohydrate.. Journal of peptide science : an official publication of the European Peptide Society, 10(1), 1-7. doi:10.1002/psc.488

    DOI: 10.1002/psc.488

    2003

    Glycosidation with a disarmed glycosyl iodide: promotion and scope. (Journal article)

    Perrie, J. A., Harding, J. R., King, C., Sinnott, D., & Stachulski, A. V. (2003). Glycosidation with a disarmed glycosyl iodide: promotion and scope.. Organic letters, 5(24), 4545-4548. doi:10.1021/ol035475k

    DOI: 10.1021/ol035475k

    Preparation, X-ray structure and reactivity of a stable glycosyl iodide. (Journal article)

    Bickley, J., Cottrell, J. A., Ferguson, J. R., Field, R. A., Harding, J. R., Hughes, D. L., . . . Stachulski, A. V. (2003). Preparation, X-ray structure and reactivity of a stable glycosyl iodide.. Chemical communications (Cambridge, England), (11), 1266-1267. doi:10.1039/b302629a

    DOI: 10.1039/b302629a

    Structure-activity relationships of some opiate glycosides. (Journal article)

    Stachulski, A. V., Scheinmann, F., Ferguson, J. R., Law, J. L., Lumbard, K. W., Hopkins, P., . . . Joel, S. P. (2003). Structure-activity relationships of some opiate glycosides.. Bioorganic & medicinal chemistry letters, 13(6), 1207-1214. doi:10.1016/s0960-894x(03)00056-8

    DOI: 10.1016/s0960-894x(03)00056-8

    Chemical Synthesis, Protein Reactivity and in vitro Cytotoxicity of Diclofenac Acyl Glucuronide' (Journal article)

    Kenny, J. R., Stachulski, A. V., Maggs, J. L., Harrell, A. W., Clarke, S. E., & Park, B. K. (2003). Chemical Synthesis, Protein Reactivity and in vitro Cytotoxicity of Diclofenac Acyl Glucuronide'. Toxicolog, 192(1), 70.

    2002

    Synthesis of morphine-[N-methyl-14C]-6-?-D-glucuronide (Journal article)

    Ferguson, J. R., Hollis, S. J., Johnston, G. A., Lumbard, K. W., & Stachulski, A. V. (2002). Synthesis of morphine-[N-methyl-14C]-6-?-D-glucuronide. Journal of Labelled Compounds and Radiopharmaceuticals, 45(2), 107-113. doi:10.1002/jlcr.540

    DOI: 10.1002/jlcr.540

    2001

    Erratum: Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin - Synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues (Journal of the Chemical Society. Perkin Transactions 1 (2001) (2682)) (Journal article)

    O'Neill, P. M., Pugh, M., Stachulski, A. V., Ward, S. A., Davies, J., & Park, B. K. (2001). Erratum: Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin - Synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues (Journal of the Chemical Society. Perkin Transactions 1 (2001) (2682)). Journal of the Chemical Society. Perkin Transactions 1, (23), 3214.

    Putative metabolites of fulvestrant, an estrogen receptor downregulator. Improved glucuronidation using trichloroacetimidates (Journal article)

    Ferguson, J. R., Harding, J. R., Killick, D. A., Lumbard, K. W., Scheinmann, F., & Stachulski, A. V. (2001). Putative metabolites of fulvestrant, an estrogen receptor downregulator. Improved glucuronidation using trichloroacetimidates. Journal of the Chemical Society, Perkin Transactions 1, (22), 3037-3041. doi:10.1039/b105397n

    DOI: 10.1039/b105397n

    Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin: synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues (Journal article)

    O'Neill, P. M., Pugh, M., Stachulski, A. V., Ward, S. A., Davies, J., & Park, B. K. (2001). Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin: synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues. Journal of the Chemical Society, Perkin Transactions 1, (20), 2682-2689. doi:10.1039/b104340b

    DOI: 10.1039/b104340b

    Glucuronidation of alcohols using the bromosugar–iodonium reagent method (Journal article)

    Stachulski, A. V. (2001). Glucuronidation of alcohols using the bromosugar–iodonium reagent method. Tetrahedron Letters, 42(37), 6611-6613. doi:10.1016/s0040-4039(01)01333-8

    DOI: 10.1016/s0040-4039(01)01333-8

    Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite. (Journal article)

    O'Neill, P. M., Scheinmann, F., Stachulski, A. V., Maggs, J. L., & Park, B. K. (2001). Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite.. Journal of medicinal chemistry, 44(9), 1467-1470. doi:10.1021/jm001061a

    DOI: 10.1021/jm001061a

    Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin. (Journal article)

    O'Neill, P. M., Miller, A., Bishop, L. P., Hindley, S., Maggs, J. L., Ward, S. A., . . . Park, B. K. (2001). Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin.. Journal of medicinal chemistry, 44(1), 58-68. doi:10.1021/jm000987f

    DOI: 10.1021/jm000987f

    The Synthesis of the Glucuronide Metabolite of UK-157,147 Using Immobilised Uridine 5'-Diphosphoglucuronyl Transferase and Traditional Organic Chemistry Techniques (Imidate Method) (Journal article)

    Webster, R., Beaumont, K., Ritzau, M., & Stachulski, A. V. (2001). The Synthesis of the Glucuronide Metabolite of UK-157,147 Using Immobilised Uridine 5'-Diphosphoglucuronyl Transferase and Traditional Organic Chemistry Techniques (Imidate Method). Biocatalysis and Biotransformation, 19(1), 69-83. doi:10.3109/10242420109103517

    DOI: 10.3109/10242420109103517

    2000

    The enzymatic glucuronidation of 3-O-protected morphine—a new route to 7,8-dihydromorphine-6-glucuronide (Journal article)

    Jenkins, G. N., Stachulski, A. V., Scheinmann, F., & Turner, N. J. (2000). The enzymatic glucuronidation of 3-O-protected morphine—a new route to 7,8-dihydromorphine-6-glucuronide. Tetrahedron: Asymmetry, 11(2), 413-416. doi:10.1016/s0957-4166(99)00582-0

    DOI: 10.1016/s0957-4166(99)00582-0

    Glucuronide and sulfate conjugates of ICI 182,780, a pure anti-estrogenic steroid. Order of addition, catalysis and substitution effects in glucuronidation (Journal article)

    Ferguson, J. R., Harding, J. R., Lumbard, K. W., Scheinmann, F., & Stachulski, A. V. (2000). Glucuronide and sulfate conjugates of ICI 182,780, a pure anti-estrogenic steroid. Order of addition, catalysis and substitution effects in glucuronidation. Tetrahedron Letters, 41(3), 389-392. doi:10.1016/s0040-4039(99)02067-5

    DOI: 10.1016/s0040-4039(99)02067-5

    Drug Metabolism: The Body's Defense against Chemical Attack (Journal article)

    Lennard, M. S., & Stachulski, A. V. (2000). Drug Metabolism: The Body's Defense against Chemical Attack. Journal of Chemical Education, 77(3), 349. doi:10.1021/ed077p349

    DOI: 10.1021/ed077p349

    1999

    Application of the TMSOTf?AgClO4 activator system to the synthesis of novel, potent, C-10 phenoxy derivatives of dihydroartemisinin (Journal article)

    O'Neill, P. M., Miller, A., Ward, S. A., Park, B. K., Scheinmann, F., & Stachulski, A. V. (1999). Application of the TMSOTf?AgClO4 activator system to the synthesis of novel, potent, C-10 phenoxy derivatives of dihydroartemisinin. Tetrahedron Letters, 40(51), 9129-9132. doi:10.1016/s0040-4039(99)01891-2

    DOI: 10.1016/s0040-4039(99)01891-2

    Syntheses and Antibacterial Activities of Tizoxanide, an N-(Nitrothiazolyl)salicylamide, and its O-Aryl Glucuronide (Journal article)

    Rossignol, J. -F., & Stachulski, A. V. (1999). Syntheses and Antibacterial Activities of Tizoxanide, an N-(Nitrothiazolyl)salicylamide, and its O-Aryl Glucuronide. Journal of Chemical Research, (1), 44-45. doi:10.1039/a806676k

    DOI: 10.1039/a806676k

    1998

    The synthesis of O-glucuronides. (Journal article)

    Stachulski, A. V., & Jenkins, G. N. (1998). The synthesis of O-glucuronides.. Natural product reports, 15(2), 173-186. doi:10.1039/a815173y

    DOI: 10.1039/a815173y

    1997

    Intermediates for Glucuronide Synthesis: 7-Hydroxycoumarin Glucuronide (Journal article)

    Brown, R. T., Scheinmann, F., & Stachulski, A. V. (1997). Intermediates for Glucuronide Synthesis: 7-Hydroxycoumarin Glucuronide. Journal of Chemical Research - Part S, (10), 370-371.

    1996

    Stereochemical and NMR Reassignment of 6-Norlysergic Acid Diethylamide and 6-Nor-6-allyllysergic Acid Diethylamide (Journal article)

    Stachulski, A. V., Nichols, D. E., & Scheinmann, F. (1996). Stereochemical and NMR Reassignment of 6-Norlysergic Acid Diethylamide and 6-Nor-6-allyllysergic Acid Diethylamide. Journal of Chemical Research - Part S, (1), 30-31.

    1995

    Efficient new syntheses of (+)- and (-)-anatoxin-a. Revised configuration of resolved 9-methyl-9-azabicyclo[4.2.1]nonan-2-one (Journal article)

    Ferguson, J. R., Lumbard, K. W., Scheinmann, F., Stachulski, A. V., Stjernlöf, P., & Sundell, S. (1995). Efficient new syntheses of (+)- and (-)-anatoxin-a. Revised configuration of resolved 9-methyl-9-azabicyclo[4.2.1]nonan-2-one. Tetrahedron Letters, 36(48), 8867-8870. doi:10.1016/0040-4039(95)01842-6

    DOI: 10.1016/0040-4039(95)01842-6

    1993

    Stereoselective synthesis of BRL 56173, a bicyclic acrylic penicillin highly stable to beta-lactamases. (Journal article)

    Atkins, R. J., Ponsford, R. J., & Stachulski, A. V. (1993). Stereoselective synthesis of BRL 56173, a bicyclic acrylic penicillin highly stable to beta-lactamases.. The Journal of antibiotics, 46(2), 362-365. doi:10.7164/antibiotics.46.362

    DOI: 10.7164/antibiotics.46.362

    Synthesis and structure-activity relationships of some 6 beta-acrylamido penicillins. (Journal article)

    Anderson, R. K., Chapman, P. C., Cosham, S. C., Davies, J. S., Grinter, T. J., Harris, M. A., . . . Smith, C. F. (1993). Synthesis and structure-activity relationships of some 6 beta-acrylamido penicillins.. The Journal of antibiotics, 46(2), 331-342. doi:10.7164/antibiotics.46.331

    DOI: 10.7164/antibiotics.46.331

    1991

    Further synthetic studies in penicillin C(6)-substitution including the versatile 6a-succinimidooxy leaving group (Journal article)

    Milner, P. H., & Stachulski, A. V. (n.d.). Further synthetic studies in penicillin C(6)-substitution including the versatile 6a-succinimidooxy leaving group. J. Chem. Soc., Perkin Trans. 1, (10), 2343-2352. doi:10.1039/p19910002343

    DOI: 10.1039/p19910002343

    Synthesis of O-vinyl oximes and derived penicillins using organoselenium intermediates (Journal article)

    Stachulski, A. V. (1991). Synthesis of O-vinyl oximes and derived penicillins using organoselenium intermediates. Journal of the Chemical Society, Perkin Transactions 1, (12), 3065. doi:10.1039/p19910003065

    DOI: 10.1039/p19910003065

    1990

    Aqueous and anhydrous degradations of 6a-formamidopenicillins (Journal article)

    Cutmore, E. A., Guest, A. W., Hatto, J. D. I., Moores, C. J., Smale, T. C., Stachulski, A. V., & Tyler, J. W. (1990). Aqueous and anhydrous degradations of 6a-formamidopenicillins. Journal of the Chemical Society, Perkin Transactions 1, (4), 847-853.

    Structure-activity relationships of some arylglycine analogues and catechol isosteres of BRL 36650, a 6 alpha-formamido penicillin. (Journal article)

    Best, D. J., Burton, G., Davies, D. T., Elder, J. S., Smale, T. C., Southgate, R., . . . Knott, S. J. (1990). Structure-activity relationships of some arylglycine analogues and catechol isosteres of BRL 36650, a 6 alpha-formamido penicillin.. The Journal of antibiotics, 43(5), 574-577. doi:10.7164/antibiotics.43.574

    DOI: 10.7164/antibiotics.43.574

    1988

    Acetonitrile: an excellent solvent for the 1,1-dichloromethylenation of certain ketones (Journal article)

    Burton, G., Elder, J. S., Fell, S. C. M., & Stachulski, A. V. (1988). Acetonitrile: an excellent solvent for the 1,1-dichloromethylenation of certain ketones. Tetrahedron Letters, 29(24), 3003-3006. doi:10.1016/0040-4039(88)85072-x

    DOI: 10.1016/0040-4039(88)85072-x

    1987

    Degradation of BRL 36650, a 6a-formamido penicillin: C(5)–C(6) bond cleavage (Journal article)

    Cutmore, E. A., Guest, A. W., Hatto, J. D. I., Smale, T. C., Stachulski, A. V., & Tyler, J. W. (n.d.). Degradation of BRL 36650, a 6a-formamido penicillin: C(5)–C(6) bond cleavage. J. Chem. Soc., Chem. Commun., (1), 21-23. doi:10.1039/c39870000021

    DOI: 10.1039/c39870000021

    1986

    Penicillin C-6 substitution using the versatile 6a-succinimido-oxy leaving group (Journal article)

    Stachulski, A. V. (n.d.). Penicillin C-6 substitution using the versatile 6a-succinimido-oxy leaving group. J. Chem. Soc., Chem. Commun., (5), 401-402. doi:10.1039/c39860000401

    DOI: 10.1039/c39860000401

    Structure-activity relationships of some 6 alpha-formamido penicillins. (Journal article)

    Guest, A. W., Harrington, F. P., Milner, P. H., Ponsford, R. J., Smale, T. C., Stachulski, A. V., . . . Slocombe, B. (1986). Structure-activity relationships of some 6 alpha-formamido penicillins.. The Journal of antibiotics, 39(10), 1498-1501. doi:10.7164/antibiotics.39.1498

    DOI: 10.7164/antibiotics.39.1498

    1985

    Penicillin C-6 substitution: a novel oxygen-bridged dimer (Journal article)

    Stachulski, A. V. (1985). Penicillin C-6 substitution: a novel oxygen-bridged dimer. Tetrahedron Letters, 26(15), 1883-1884. doi:10.1016/s0040-4039(00)94764-6

    DOI: 10.1016/s0040-4039(00)94764-6

    1984

    6a(7a)-Formamido penicillins and cephalosporins (Journal article)

    Milner, P. H., Guest, A. W., Harrington, F. P., Ponsford, R. J., Smale, T. C., & Stachulski, A. V. (n.d.). 6a(7a)-Formamido penicillins and cephalosporins. J. Chem. Soc., Chem. Commun., (20), 1335-1336. doi:10.1039/c39840001335

    DOI: 10.1039/c39840001335

    The chemistry of some 2-aminothiazol-4-ylacetic acid derivatives and the synthesis of derived penicillins (Journal article)

    Hardy, K. D., Harrington, F. P., & Stachulski, A. V. (1984). The chemistry of some 2-aminothiazol-4-ylacetic acid derivatives and the synthesis of derived penicillins. Journal of the Chemical Society, Perkin Transactions 1, 1227. doi:10.1039/p19840001227

    DOI: 10.1039/p19840001227

    1983

    Biosynthesis. Part 26. Synthetic studies on structural modification of late biosynthetic precursors for colchicine (Journal article)

    Battersby, A. R., McDonald, E., & Stachulski, A. V. (1983). Biosynthesis. Part 26. Synthetic studies on structural modification of late biosynthetic precursors for colchicine. Journal of the Chemical Society, Perkin Transactions 1, 3053. doi:10.1039/p19830003053

    DOI: 10.1039/p19830003053

    1982

    Oxidation of benzyloxycarbonyl threonine and serine methyl esters to an oxamate derivative (Journal article)

    Stachulski, A. V. (1982). Oxidation of benzyloxycarbonyl threonine and serine methyl esters to an oxamate derivative. Tetrahedron Letters, 23(37), 3789-3790. doi:10.1016/s0040-4039(00)87707-2

    DOI: 10.1016/s0040-4039(00)87707-2

    1979

    Synthesis and biological activities of [7-(azetidine-2-carboxylic acid)]-oxytocin and -lysine-vasopressin. (Journal article)

    Barber, M., Jones, J. H., Stachulski, A. V., Bisset, G. W., Chowdrey, H. S., & Hudson, A. L. (1979). Synthesis and biological activities of [7-(azetidine-2-carboxylic acid)]-oxytocin and -lysine-vasopressin.. International journal of peptide and protein research, 14(3), 247-261. doi:10.1111/j.1399-3011.1979.tb01931.x

    DOI: 10.1111/j.1399-3011.1979.tb01931.x

    The use of the N(p)-phenacyl group for the protection of the histidine side chain in peptide synthesis (Journal article)

    Fletcher, A. R., Jones, J. H., Ramage, W. I., & Stachulski, A. V. (n.d.). The use of the N(p)-phenacyl group for the protection of the histidine side chain in peptide synthesis. J. Chem. Soc., Perkin Trans. 1, (0), 2261-2267. doi:10.1039/p19790002261

    DOI: 10.1039/p19790002261