2024
Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractile-strain-driven collagen degradation (Journal article)
Saini, K., Cho, S., Tewari, M., Jalil, A., Wang, M., Kasznel, A., . . . Discher, D. E. (2024). Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractile-strain-driven collagen degradation. Biophysical Journal, 123(3), 469a. doi:10.1016/j.bpj.2023.11.2834DOI: 10.1016/j.bpj.2023.11.2834
Yamamoto, K., Isohata, M., & Higashi, S. (2024). Expression and Purification of Active Monomeric MMP7.. Methods in molecular biology (Clifton, N.J.), 2747, 67-73. doi:10.1007/978-1-0716-3589-6_6DOI: 10.1007/978-1-0716-3589-6_6
2023
Minns, A. F., Qi, Y., Yamamoto, K., Lee, K., & Santamaria, S. (2022). The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 299(4). doi:10.1016/j.jbc.2023.103048DOI: 10.1016/j.jbc.2023.103048
Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen (Conference Paper)
Saini, K., Cho, S., Tewari, M., Jalil, A., Wang, M., Vashisth, M., . . . Discher, D. E. (2023). Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen. In BIOPHYSICAL JOURNAL Vol. 122 (pp. 87A). Retrieved from https://www.webofscience.com/
Kwok, H. F., Yamamoto, K., de Groot, R., Scilabra, S. D., & Santamaria, S. (2023). Editorial: ADAM, ADAMTS and astacin proteases: Challenges and breakthroughs in the -Omics era-Volume II. FRONTIERS IN MOLECULAR BIOSCIENCES, 10. doi:10.3389/fmolb.2023.1172288DOI: 10.3389/fmolb.2023.1172288
Increased LANTA31 activates Akt signalling in breast cancer and changes the mode of tumour invasion into laminin matrixes (Conference Paper)
Asiri, F. M., Troughton, L. D., Zech, T., Bou-Gharios, G., Yamamoto, K., & Hamill, K. J. (2023). Increased LANTA31 activates Akt signalling in breast cancer and changes the mode of tumour invasion into laminin matrixes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A10). Retrieved from https://www.webofscience.com/
Interaction of Wnts and low-density lipoprotein receptor-related protein 1 in cartilage development (Conference Paper)
Gremida, A. M. E., Jensen, A., Alhashmi, M., Mogensen, E. H., Thogersen, I. B., Enghild, J. J., . . . Yamamoto, K. (2023). Interaction of Wnts and low-density lipoprotein receptor-related protein 1 in cartilage development. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A6-A7). Retrieved from https://www.webofscience.com/
LANT α31 induces an epithelial to mesenchymal-like transition in pancreatic adenocarcinoma cells and changes laminin α3 expression (Conference Paper)
Sari, B., Hamill, K. J., Zech, T., & Yamamoto, K. (2023). LANT α31 induces an epithelial to mesenchymal-like transition in pancreatic adenocarcinoma cells and changes laminin α3 expression. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A8). Retrieved from https://www.webofscience.com/
Optimisation of a proteomic workflow for the extraction of extracellular matrix proteins within dental tissues (Conference Paper)
Jensen, A., Peffers, M., Jarad, F., & Yamamoto, K. (2023). Optimisation of a proteomic workflow for the extraction of extracellular matrix proteins within dental tissues. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A14). Retrieved from https://www.webofscience.com/
Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice (Conference Paper)
Kobayashi, Y., Yamamoto, K., Kanakis, I., Yamashita, Y., Sakai, T., Jarad, F., . . . Ooi, K. (2023). Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A9). Retrieved from https://www.webofscience.com/
Transcriptional elements driving MMP13 in development (Conference Paper)
AlSalhi, S. I., Alhashmi, M., Young, D., Tew, S., Yamamoto, K., & Bou-Gharios, G. (2023). Transcriptional elements driving MMP13 in development. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A5). Retrieved from https://www.webofscience.com/
2022
Al-Maslamani, N. A., Oldershaw, R., Tew, S., Curran, J., D'Hooghe, P., Yamamoto, K., & Horn, H. F. (2022). Chondrocyte De-Differentiation: Biophysical Cues to Nuclear Alterations. CELLS, 11(24). doi:10.3390/cells11244011DOI: 10.3390/cells11244011
Yamamoto, K., Scavenius, C., Meschis, M. M., Gremida, A. M. E., Mogensen, E. H., Thøgersen, I. B., . . . Nagase, H. (2022). A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.. Matrix biology : journal of the International Society for Matrix Biology, S0945-053X(22)00101-9. doi:10.1016/j.matbio.2022.08.007DOI: 10.1016/j.matbio.2022.08.007
Mogensen, E. H., Poulsen, E. T., Thogersen, I. B., Yamamoto, K., Bruel, A., & Enghild, J. J. (2022). The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea. EXPERIMENTAL EYE RESEARCH, 219. doi:10.1016/j.exer.2022.109081DOI: 10.1016/j.exer.2022.109081
Uncovering the ligandome of low-density lipoprotein receptor-related protein 1 in cartilage: a top-down approach to identify therapeutic targets (Preprint)
DOI: 10.1101/2022.03.02.482546
Heterogeneous strains in tissue suppress collagen degradation by collagenases (Conference Paper)
Saini, K., Tewari, M., Cho, S., Vashisth, M., Jalil, A., Andrechak, J. C., . . . Discher, D. E. (2022). Heterogeneous strains in tissue suppress collagen degradation by collagenases. In BIOPHYSICAL JOURNAL Vol. 121 (pp. 492A). Retrieved from https://www.webofscience.com/
Wilkinson, D. J., Falconer, A. M. D., Wright, H. L., Lin, H., Yamamoto, K., Cheung, K., . . . Rowan, A. D. (2022). Matrix metalloproteinase-13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha-1 antitrypsin: Implications for osteoarthritis. FEBS JOURNAL, 289(1), 121-139. doi:10.1111/febs.16127DOI: 10.1111/febs.16127
2021
Santamaria, S., Martin, D. R., Dong, X., Yamamoto, K., Apte, S. S., & Ahnstrom, J. (2021). Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8. JOURNAL OF BIOLOGICAL CHEMISTRY, 297(5). doi:10.1016/j.jbc.2021.101323DOI: 10.1016/j.jbc.2021.101323
Yamamoto, K., de Groot, R., Scilabra, S. D., Kwok, H. F., & Santamaria, S. (2021). Editorial: ADAM, ADAMTS and Astacin Proteases: Challenges and Breakthroughs in the -Omics Era. FRONTIERS IN MOLECULAR BIOSCIENCES, 8. doi:10.3389/fmolb.2021.780242DOI: 10.3389/fmolb.2021.780242
Yamamoto, K., Wilkinson, D., & Bou-Gharios, G. (n.d.). Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis. Calcified Tissue International. doi:10.1007/s00223-020-00739-7DOI: 10.1007/s00223-020-00739-7
Harwood, S. L., Nielsen, N. S., Diep, K., Jensen, K. T., Nielsen, P. K., Yamamoto, K., & Enghild, J. J. (2021). Development of selective protease inhibitors <i>via</i> engineering of the bait region of human α<sub>2</sub>-macroglobulin. JOURNAL OF BIOLOGICAL CHEMISTRY, 297(1). doi:10.1016/j.jbc.2021.100879DOI: 10.1016/j.jbc.2021.100879
IDENTIFICATION OF A NOVEL REGULATOR OF ADAMTS-5-MEDIATED AGGRECAN DEGRADATION IN CHONDROCYTES (Conference Paper)
Collins, I., Yamamoto, K., Troeberg, L., & Wann, A. K. (2021). IDENTIFICATION OF A NOVEL REGULATOR OF ADAMTS-5-MEDIATED AGGRECAN DEGRADATION IN CHONDROCYTES. In OSTEOARTHRITIS AND CARTILAGE Vol. 29 (pp. S100). Retrieved from https://www.webofscience.com/
Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation where Strains are High (Conference Paper)
Saini, K., Tewari, M., Cho, S., Jalil, A., Irianto, J., Vashisth, M., . . . Discher, D. E. (2021). Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation where Strains are High. In BIOPHYSICAL JOURNAL Vol. 120 (pp. 102A). Retrieved from https://www.webofscience.com/
Identification of a novel regulator of ADAMTS-5-mediated aggrecan degradation in chondrocytes (Conference Paper)
Collins, I., Coveney, C. R., Yamamoto, K., Troeberg, L., & Wann, A. K. T. (2021). Identification of a novel regulator of ADAMTS-5-mediated aggrecan degradation in chondrocytes. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 102 (pp. 120-121). Retrieved from https://www.webofscience.com/
\ Fibroblast-specific deletion of cell-surface endocytic receptor LRP1 prevents the development of pulmonary fibrosis in mouse in vivo (Conference Paper)
Meschis, M. M., Scavenius, C., Enghild, J. J., Craig, S., Bou-Gharios, G., & Yamamoto, K. (2021). \ Fibroblast-specific deletion of cell-surface endocytic receptor LRP1 prevents the development of pulmonary fibrosis in mouse in vivo. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 102 (pp. A14). Retrieved from https://www.webofscience.com/
2020
Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation Where Strains are High (Conference Paper)
Saini, K., Tewari, M., Cho, S., Jalil, A., Irianto, J., Vashisth, M., . . . Discher, D. E. (2020). Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation Where Strains are High. In BIOPHYSICAL JOURNAL Vol. 118 (pp. 398A). Retrieved from https://www.webofscience.com/
Analysis of Aggrecanase Activity Using Neoepitope Antibodies (Chapter)
Santamaria, S., & Yamamoto, K. (2020). Analysis of Aggrecanase Activity Using Neoepitope Antibodies. In ADAMTS PROTEASES: METHODS AND PROTOCOLS (Vol. 2043, pp. 125-136). doi:10.1007/978-1-4939-9698-8_11DOI: 10.1007/978-1-4939-9698-8_11
Endocytosis of extracellular molecules in respiratory health and disease (Conference Paper)
Meschis, M. M., Scavenius, C., Enghild, J. J., Craig, S., Bou-Gharios, G., & Yamamoto, K. (2020). Endocytosis of extracellular molecules in respiratory health and disease. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 101 (pp. A3). Retrieved from https://www.webofscience.com/
2019
Mirastschijski, U., Lupse, B., Maedler, K., Sarma, B., Radtke, A., Belge, G., . . . Agren, M. S. (2019). Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(20). doi:10.3390/ijms20205234DOI: 10.3390/ijms20205234
Scavenius, C., Poulsen, E. C., Thøgersen, I. B., Roebuck, M., Frostick, S., Bou-Gharios, G., . . . Enghild, J. J. (2019). Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients. Journal of Biological Chemistry, 294(42), 15495-15504. doi:10.1074/jbc.ra119.008844DOI: 10.1074/jbc.ra119.008844
Santamaria, S., Yamamoto, K., Teraz-Orosz, A., Koch, C., Apte, S. S., de Groot, R., . . . Ahnstrom, J. (2019). Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-47494-wDOI: 10.1038/s41598-019-47494-w
Laminin N-terminus α31 regulates keratinocyte adhesion and migration through modifying the organisation and proteolytic processing of laminin 332 (Journal article)
Troughton, L., Iorio, V., Shaw, L., Sugden, C., Yamamoto, K., & Hamill, K. (2019). Laminin N-terminus α31 regulates keratinocyte adhesion and migration through modifying the organisation and proteolytic processing of laminin 332. doi:10.1101/617597DOI: 10.1101/617597
2018
Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP-1-mediated endocytosis. (Journal article)
Coveney, C. R., Collins, I., Mc Fie, M., Chanalaris, A., Yamamoto, K., & Wann, A. K. T. (2018). Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP-1-mediated endocytosis.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(12), 6771-6782. doi:10.1096/fj.201800334DOI: 10.1096/fj.201800334
INHIBITION OF LRP1 SHEDDING REVERSES CARTILAGE DEGRADATION IN OSTEOARTHRITIS (Conference Paper)
Yamamoto, K., Scavenius, C., Santamaria, S., Botkjaer, K. A., Dudhia, J., Troeberg, L., . . . Nagase, H. (2018). INHIBITION OF LRP1 SHEDDING REVERSES CARTILAGE DEGRADATION IN OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S22). doi:10.1016/j.joca.2018.02.060DOI: 10.1016/j.joca.2018.02.060
2017
Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signalling (Conference Paper)
Ghadiali, R. S., Guimond, S. E., Turnbull, J. E., & Pisconti, A. (2017). Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signalling. In International Journal of Experimental Pathology: mechanisms and models of disease Vol. 98 (pp. A3-A4). University of Oxford: Wiley. doi:10.1111/iep.12235DOI: 10.1111/iep.12235
Yamamoto, K., Santamaria, S., Botkjaer, K. A., Dudhia, J., Troeberg, L., Itoh, Y., . . . Nagase, H. (2017). Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis.. Arthritis & rheumatology (Hoboken, N.J.), 69(6), 1246-1256. doi:10.1002/art.40080DOI: 10.1002/art.40080
Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue. (Journal article)
Scilabra, S. D., Yamamoto, K., Pigoni, M., Sakamoto, K., Müller, S. A., Papadopoulou, A., . . . Kadomatsu, K. (2017). Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue.. Matrix Biology, 59, 69-79. doi:10.1016/j.matbio.2016.07.004DOI: 10.1016/j.matbio.2016.07.004
Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1 (Journal article)
Santamaria, S., Fedorov, O., McCafferty, J., Murphy, G., Dudhia, J., Nagase, H., & Yamamoto, K. (2017). Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1. mAbs, 9(4), 595-602. doi:10.1080/19420862.2017.1304341DOI: 10.1080/19420862.2017.1304341
A comparison of COMP (TSP5) proteolysis by ADAMTS7 and ADAMTS4 (Conference Paper)
Santamaria, S., Crawley, J. T. B., Yamamoto, K., Ahnstrom, J., & de Groot, R. (2017). A comparison of COMP (TSP5) proteolysis by ADAMTS7 and ADAMTS4. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 98 (pp. A3-A4). Retrieved from https://www.webofscience.com/
2016
MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1. (Journal article)
Yamamoto, K., Okano, H., Miyagawa, W., Visse, R., Shitomi, Y., Santamaria, S., . . . Nagase, H. (2016). MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1.. Matrix biology : journal of the International Society for Matrix Biology, 56, 57-73. doi:10.1016/j.matbio.2016.03.007DOI: 10.1016/j.matbio.2016.03.007
Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis (Journal article)
Ismail, H. M., Miotla-Zarebska, J., Troeberg, L., Tang, X., Stott, B., Yamamoto, K., . . . Saklatvala, J. (2016). Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis. Arthritis and Rheumatology, 68(5), 1165-1171. doi:10.1002/art.39547DOI: 10.1002/art.39547
2015
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2) (Journal article)
Santamaria, S., Yamamoto, K., Botkjaer, K., Tape, C., Dyson, M. R., McCafferty, J., . . . Nagase, H. (2015). Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2). The Biochemical journal, 471(3), 391-401. doi:10.1042/BJ20150758DOI: 10.1042/BJ20150758
Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes (Journal article)
Ismail, H. M., Yamamoto, K., Vincent, T. L., Nagase, H., Troeberg, L., & Saklatvala, J. (2015). Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes. Arthritis and Rheumatology, 67(7), 1826-1836. doi:10.1002/art.39099DOI: 10.1002/art.39099
Extracellular regulation of metalloproteinases. (Journal article)
Yamamoto, K., Murphy, G., & Troeberg, L. (2015). Extracellular regulation of metalloproteinases.. Matrix biology : journal of the International Society for Matrix Biology, 44-46, 255-263. doi:10.1016/j.matbio.2015.02.007DOI: 10.1016/j.matbio.2015.02.007
A significant role for the JNK pathway in regulating interleukin 1 induced-aggrecan degradation in human articular chondrocytes (Journal article)
Ismail, H. M., Yamamoto, K., Vincent, T., Nagase, H., Troeberg, L., & Saklatvala, J. (2015). A significant role for the JNK pathway in regulating interleukin 1 induced-aggrecan degradation in human articular chondrocytes. Osteoarthritis and Cartilage, 23, A152. doi:10.1016/j.joca.2015.02.902DOI: 10.1016/j.joca.2015.02.902
Metalloproteinase‐dependent and ‐independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs‐15 (Journal article)
Kelwick, R., Wagstaff, L., Decock, J., Roghi, C., Cooley, L. S., Robinson, S. D., . . . Edwards, D. R. (2015). Metalloproteinase‐dependent and ‐independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs‐15. International journal of cancer, 136(4), E14-E26. doi:10.1002/ijc.29129DOI: 10.1002/ijc.29129
2014
Autofluorescence lifetime metrology for label-free detection of cartilage matrix degradation (Conference Paper)
Nickdel, M. B., Lagarto, J. L., Kelly, D. J., Manning, H. B., Yamamoto, K., Talbot, C. B., . . . Itoh, Y. (2014). Autofluorescence lifetime metrology for label-free detection of cartilage matrix degradation. In R. R. Alfano, & S. G. Demos (Eds.), SPIE Proceedings. SPIE. doi:10.1117/12.2037285DOI: 10.1117/12.2037285
Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4): FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING (Journal article)
Yamamoto, K., Owen, K., Parker, A. E., Scilabra, S. D., Dudhia, J., Strickland, D. K., . . . Nagase, H. (2014). Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4): FUNCTIONAL DIFFERENCES OF NON-CATALYTIC DOMAINS OF ADAMTS-4 AND ADAMTS-5 IN LRP1 BINDING. The Journal of biological chemistry, 289(10), 6462-6474. doi:10.1074/jbc.m113.545376DOI: 10.1074/jbc.m113.545376
Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin. (Journal article)
Yamamoto, K., Miyazaki, K., & Higashi, S. (2014). Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin.. The FEBS journal, 281(15), 3346-3356. doi:10.1111/febs.12865DOI: 10.1111/febs.12865
2013
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: synthesis and biological evaluation. (Journal article)
Nuti, E., Santamaria, S., Casalini, F., Yamamoto, K., Marinelli, L., La Pietra, V., . . . Rossello, A. (2013). Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: synthesis and biological evaluation.. European journal of medicinal chemistry, 62, 379-394. doi:10.1016/j.ejmech.2012.12.058DOI: 10.1016/j.ejmech.2012.12.058
LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage. (Journal article)
Yamamoto, K., Troeberg, L., Scilabra, S. D., Pelosi, M., Murphy, C. L., Strickland, D. K., & Nagase, H. (2013). LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(2), 511-521. doi:10.1096/fj.12-216671DOI: 10.1096/fj.12-216671
Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1. (Journal article)
Scilabra, S. D., Troeberg, L., Yamamoto, K., Emonard, H., Thøgersen, I., Enghild, J. J., . . . Nagase, H. (2013). Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.. The Journal of biological chemistry, 288(1), 332-342. doi:10.1074/jbc.m112.393322DOI: 10.1074/jbc.m112.393322
Autofluorescence lifetime imaging and metrology for medical research and clinical diagnosis (Conference Paper)
Coda, S., Kelly, D., Lagarto, J., Manning, H., Patalay, R., Sparks, H., . . . French, P. M. (2013). Autofluorescence lifetime imaging and metrology for medical research and clinical diagnosis. In Optics in the Life Sciences. OSA. doi:10.1364/omp.2013.mt3c.4DOI: 10.1364/omp.2013.mt3c.4
Detection of cartilage matrix degradation by autofluorescence lifetime. (Journal article)
Manning, H. B., Nickdel, M. B., Yamamoto, K., Lagarto, J. L., Kelly, D. J., Talbot, C. B., . . . Itoh, Y. (2013). Detection of cartilage matrix degradation by autofluorescence lifetime.. Matrix biology : journal of the International Society for Matrix Biology, 32(1), 32-38. doi:10.1016/j.matbio.2012.11.012DOI: 10.1016/j.matbio.2012.11.012
2010
Cholesterol sulfate alters substrate preference of matrix metalloproteinase-7 and promotes degradations of pericellular laminin-332 and fibronectin. (Journal article)
Yamamoto, K., Miyazaki, K., & Higashi, S. (2010). Cholesterol sulfate alters substrate preference of matrix metalloproteinase-7 and promotes degradations of pericellular laminin-332 and fibronectin.. The Journal of biological chemistry, 285(37), 28862-28873. doi:10.1074/jbc.m110.136994DOI: 10.1074/jbc.m110.136994
2008
Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate. (Journal article)
Higashi, S., Oeda, M., Yamamoto, K., & Miyazaki, K. (2008). Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate.. The Journal of biological chemistry, 283(51), 35735-35744. doi:10.1074/jbc.m806285200DOI: 10.1074/jbc.m806285200
Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces. (Journal article)
Tsunezumi, J., Yamamoto, K., Higashi, S., & Miyazaki, K. (2008). Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces.. The FEBS journal, 275(19), 4810-4823. doi:10.1111/j.1742-4658.2008.06620.xDOI: 10.1111/j.1742-4658.2008.06620.x
2006
Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion. (Journal article)
Yamamoto, K., Higashi, S., Kioi, M., Tsunezumi, J., Honke, K., & Miyazaki, K. (2006). Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion.. The Journal of biological chemistry, 281(14), 9170-9180. doi:10.1074/jbc.m510377200DOI: 10.1074/jbc.m510377200
2003
Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model. (Journal article)
Kioi, M., Yamamoto, K., Higashi, S., Koshikawa, N., Fujita, K., & Miyazaki, K. (2003). Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model.. Oncogene, 22(54), 8662-8670. doi:10.1038/sj.onc.1207181DOI: 10.1038/sj.onc.1207181
Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity. (Journal article)
Ahmed, S., Yamamoto, K., Sato, Y., Ogawa, T., Herrmann, A., Higashi, S., & Miyazaki, K. (2003). Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity.. Biochemical and biophysical research communications, 310(2), 612-618. doi:10.1016/j.bbrc.2003.09.058DOI: 10.1016/j.bbrc.2003.09.058
