2023
Pollock, N., Macpherson, P. C., Staunton, C. A., Hemmings, K., Davis, C. S., Owen, E. D., . . . Jackson, M. J. (2023). Deletion of <i>Sod1</i> in Motor Neurons Exacerbates Age-Related Changes in Axons and Neuromuscular Junctions in Mice.. eNeuro, 10(3), ENEURO.0086-ENEU22.2023. doi:10.1523/eneuro.0086-22.2023DOI: 10.1523/eneuro.0086-22.2023
O'Brien, F., Feetham, C. H., Staunton, C. A., Hext, K., & Barrett-Jolley, R. (2023). Temperature modulates PVN pre-sympathetic neurones via transient receptor potential ion channels.. Frontiers in pharmacology, 14, 1256924. doi:10.3389/fphar.2023.1256924DOI: 10.3389/fphar.2023.1256924
The effect of maternal and early-life nutrition on redox homeostasis (Chapter)
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3DOI: 10.1016/b978-0-443-19247-0.00002-3
2022
O'Brien, F., Staunton, C. A., & Barrett-Jolley, R. (2022). Systemic application of the transient receptor potential vanilloid-type 4 antagonist GSK2193874 induces tail vasodilation in a mouse model of thermoregulation. BIOLOGY LETTERS, 18(6). doi:10.1098/rsbl.2022.0129DOI: 10.1098/rsbl.2022.0129
Jackson, M. J., Pollock, N., Staunton, C., Jones, S., & McArdle, A. (2022). Redox Control of Signalling Responses to Contractile Activity and Ageing in Skeletal Muscle. CELLS, 11(10). doi:10.3390/cells11101698DOI: 10.3390/cells11101698
Altered oxidative DNA damage repair systems in muscles of old mice: role in the age-related increase in muscle production of cytokines/chemokines (Journal article)
Kumiscia, K., Shigdar, S., Owen, E., Staunton, C. A., Proctor, C. J., Jackson, M. J., . . . McArdle, A. (2022). Altered oxidative DNA damage repair systems in muscles of old mice: role in the age-related increase in muscle production of cytokines/chemokines. FASEB JOURNAL, 36. doi:10.1096/fasebj.2022.36.S1.R4404DOI: 10.1096/fasebj.2022.36.S1.R4404
Combined transcriptomic, proteomic and synthesis profiling reveal distinct proteostatic signatures for skeletal muscle of adult and old mice (Journal article)
Staunton, C. A., Owen, E. D., Hemmings, K., Jackson, M. J., Barrett-Jolley, R., Hammond, D., . . . McArdle, A. (2022). Combined transcriptomic, proteomic and synthesis profiling reveal distinct proteostatic signatures for skeletal muscle of adult and old mice. FASEB JOURNAL, 36. doi:10.1096/fasebj.2022.36.S1.R4458DOI: 10.1096/fasebj.2022.36.S1.R4458
Cytokine and Chemokine Release from Immortalised Human Myotubes in Culture: Effect of Contractions and Comparison with Isolated Intact Mature Adult Murine Muscle Fibres (Journal article)
Neiland, H. J., Staunton, C. A., Owen, E., Kumiscia, J., Shigdar, S., Jones, S. W., . . . McArdle, A. (2022). Cytokine and Chemokine Release from Immortalised Human Myotubes in Culture: Effect of Contractions and Comparison with Isolated Intact Mature Adult Murine Muscle Fibres. FASEB JOURNAL, 36. doi:10.1096/fasehj.2022.36.S1.L7908DOI: 10.1096/fasehj.2022.36.S1.L7908
Staunton, C. A., Owen, E. D., Hemmings, K., Vasilaki, A., McArdle, A., Barrett-Jolley, R., & Jackson, M. J. (2022). Skeletal muscle transcriptomics identifies common pathways in nerve crush injury and ageing. SKELETAL MUSCLE, 12(1). doi:10.1186/s13395-021-00283-4DOI: 10.1186/s13395-021-00283-4
Deletion of <i>Sod1</i> in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice (Preprint)
DOI: 10.1101/2022.01.27.477840
2021
Redox cross talk from motor nerves to skeletal muscle regulates muscle redox homeostasis (Conference Paper)
Jackson, M. J., Pollock, N., Staunton, C., Hemmings, K., Vasilaki, A., & McArdle, A. (2021). Redox cross talk from motor nerves to skeletal muscle regulates muscle redox homeostasis. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 177. doi:10.1016/j.freeradbiomed.2021.08.047DOI: 10.1016/j.freeradbiomed.2021.08.047
Systemic application of the TRPV4 antagonist GSK2193874 induces tail vasodilation in a mouse model of thermoregulation (Journal article)
O’Brien, F., Staunton, C., & Barrett-Jolley, R. (2021). Systemic application of the TRPV4 antagonist GSK2193874 induces tail vasodilation in a mouse model of thermoregulation. doi:10.1101/2021.03.12.435126DOI: 10.1101/2021.03.12.435126
Development of age-related loss of muscle mass and function - role of oxidative DNA damage repair systems (Conference Paper)
Kumiscia, K., Shigdar, S., Proctor, C., Shanley, D., Owen, E., Staunton, C., . . . McArdle, A. (2021). Development of age-related loss of muscle mass and function - role of oxidative DNA damage repair systems. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 165. doi:10.1016/j.freeradbiomed.2020.12.339DOI: 10.1016/j.freeradbiomed.2020.12.339
Extracellular Vesicle Production by Skeletal Muscle: Role in Neuromuscular Ageing (Conference Paper)
Hemmings, K., Pollock, N., Owen, E., Staunton, C., Brooks, S. V., & McArdle, A. (2021). Extracellular Vesicle Production by Skeletal Muscle: Role in Neuromuscular Ageing. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 165. doi:10.1016/j.freeradbiomed.2020.12.334DOI: 10.1016/j.freeradbiomed.2020.12.334
Neuron specific lack of SOD1 leads to accelerated age-related loss of NMJ structure (Conference Paper)
Pollock, N., Hemmings, K., Staunton, C. A., Owen, E. D., Scalabrin, M., Vasilaki, A., . . . Jackson, M. J. (2021). Neuron specific lack of SOD1 leads to accelerated age-related loss of NMJ structure. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 165. doi:10.1016/j.freeradbiomed.2020.12.304DOI: 10.1016/j.freeradbiomed.2020.12.304
2020
Exosomal Signaling by Skeletal Muscle: Role in Neuromuscular Ageing (Conference Paper)
Hemmings, K., Owen, E., Staunton, C., Pollock, N., Brooks, S. V., & McArdle, A. (2020). Exosomal Signaling by Skeletal Muscle: Role in Neuromuscular Ageing. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 159 (pp. S105-S106). doi:10.1016/j.freeradbiomed.2020.10.268DOI: 10.1016/j.freeradbiomed.2020.10.268
Lack of SOD1 In Neuronal Tissue Affects Neuromuscular Junction Stability in Advanced Age (Conference Paper)
Pollock, N., Hemmings, K., Staunton, C., Owen, E., MacPherson, P., Vasilaki, A., . . . Jackson, M. (2020). Lack of SOD1 In Neuronal Tissue Affects Neuromuscular Junction Stability in Advanced Age. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 159 (pp. S108-S109). doi:10.1016/j.freeradbiomed.2020.10.275DOI: 10.1016/j.freeradbiomed.2020.10.275
Transcriptomic analysis of skeletal muscle ageing: focus on neurotrophic factors and ROS-related genes (Conference Paper)
Staunton, C., McArdle, A., Barrett-Jolley, R., & Jackson, M. (2020). Transcriptomic analysis of skeletal muscle ageing: focus on neurotrophic factors and ROS-related genes. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 159 (pp. S110-S111). doi:10.1016/j.freeradbiomed.2020.10.280DOI: 10.1016/j.freeradbiomed.2020.10.280
Bhaskaran, S., Pollock, N., Macpherson, P. C., Ahn, B., Piekarz, K. M., Staunton, C. A., . . . Van Remmen, H. (2020). Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice. AGING CELL, 19(10). doi:10.1111/acel.13225DOI: 10.1111/acel.13225
Altered Redox Signalling in both Muscle and Nerve are Required for Neuromuscular Breakdown (Conference Paper)
Pollock, N., Hemmings, K., Staunton, C., Owen, E., Scalabrin, M., Macpherson, P., . . . Jackson, M. (2020). Altered Redox Signalling in both Muscle and Nerve are Required for Neuromuscular Breakdown. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.05492DOI: 10.1096/fasebj.2020.34.s1.05492
Genomic Profiling and Physiological Approaches to Understand Aquaporins and their Role in ROS Signalling within Skeletal Muscle (Conference Paper)
Staunton, C., Vasilaki, A., McArdle, A., Jackson, M., & Barrett-Jolley, R. (2020). Genomic Profiling and Physiological Approaches to Understand Aquaporins and their Role in ROS Signalling within Skeletal Muscle. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.02026DOI: 10.1096/fasebj.2020.34.s1.02026
Rates of Synthesis of Individual Proteins in Muscles of Old Mice: A Heavy Water Approach (Conference Paper)
Owen, E., Hammond, D., Staunton, C., Franco, C., Prescott, M., Brooks, S., . . . McArdle, A. (2020). Rates of Synthesis of Individual Proteins in Muscles of Old Mice: A Heavy Water Approach. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.06592DOI: 10.1096/fasebj.2020.34.s1.06592
The Contribution of Environment to Impair Re-Innervation in Age-Related Failure of Muscle Regeneration Following (Conference Paper)
Pollock, N., Owen, E., Staunton, C., Davis, C., Vasilaki, A., Richardson, A., . . . McArdle, A. (2020). The Contribution of Environment to Impair Re-Innervation in Age-Related Failure of Muscle Regeneration Following. In FASEB JOURNAL Vol. 34. doi:10.1096/fasebj.2020.34.s1.05784DOI: 10.1096/fasebj.2020.34.s1.05784
Haidar, O., O'Neill, N., Staunton, C. A., Bavan, S., O'Brien, F., Zouggari, S., . . . Barrett-Jolley, R. (2020). Pro-inflammatory Cytokines Drive Deregulation of Potassium Channel Expression in Primary Synovial Fibroblasts. FRONTIERS IN PHYSIOLOGY, 11. doi:10.3389/fphys.2020.00226DOI: 10.3389/fphys.2020.00226
2019
Staunton, C. A., Owen, E. D., Pollock, N., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. J. (2019). HyPer2 imaging reveals temporal and heterogeneous hydrogen peroxide changes in denervated and aged skeletal muscle fibers in vivo. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-51035-wDOI: 10.1038/s41598-019-51035-w
Vasilaki, A. (n.d.). Redox responses in skeletal muscle following denervation. Redox Biology.
Genomic Profiling using RNAseq to identify key drivers of sarcopenia and motor unit turnover in murine skeletal muscle (Conference Paper)
Staunton, C. A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. (2019). Genomic Profiling using RNAseq to identify key drivers of sarcopenia and motor unit turnover in murine skeletal muscle. In FASEB JOURNAL Vol. 33. Retrieved from https://www.webofscience.com/
Neuromuscular Junction Structure and Redox Status of Skeletal Muscle Fiber: Effect on Schwann Cells (Conference Paper)
Pollock, N., Scalabrin, M., Staunton, C. A., Vasilaki, A., Van Remmen, H., Richardson, A., . . . Jackson, M. J. (2019). Neuromuscular Junction Structure and Redox Status of Skeletal Muscle Fiber: Effect on Schwann Cells. In FASEB JOURNAL Vol. 33. Retrieved from https://www.webofscience.com/
McArdle, A., Pollock, N., Staunton, C. A., & Jackson, M. J. (2019). Aberrant redox signalling and stress response in age-related muscle decline: Role in inter- and intra-cellular signalling. FREE RADICAL BIOLOGY AND MEDICINE, 132, 50-57. doi:10.1016/j.freeradbiomed.2018.11.038DOI: 10.1016/j.freeradbiomed.2018.11.038
Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species (Chapter)
Jackson, M. J., Pollock, N., Staunton, C. A., Stretton, C., Vasilaki, A., & McArdle, A. (2020). Oxidative stress in skeletal muscle: Unraveling the potential beneficial and deleterious roles of reactive oxygen species. In OXIDATIVE STRESS: EUSTRESS AND DISTRESS (pp. 713-733). doi:10.1016/B978-0-12-818606-0.00034-1DOI: 10.1016/B978-0-12-818606-0.00034-1
Reactive oxygen species in age-related decline of skeletal muscle and the musculoskeletal system (Conference Paper)
Jackson, M., McArdle, A., Pollock, N., Staunton, C., Stretton, C., & Vasilaki, A. (2019). Reactive oxygen species in age-related decline of skeletal muscle and the musculoskeletal system. In EUROPEAN JOURNAL OF CLINICAL INVESTIGATION Vol. 49 (pp. 46). Retrieved from https://www.webofscience.com/
2018
Aberrant redox signaling in age-related muscle decline (Conference Paper)
McArdle, A., Pollock, N., Staunton, C. A., Owen, E., Shigdar, S., Scalabrin, M., . . . Jackson, M. J. (2018). Aberrant redox signaling in age-related muscle decline. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 120 (pp. S13-S14). doi:10.1016/j.freeradbiomed.2018.04.059DOI: 10.1016/j.freeradbiomed.2018.04.059
ANALYSIS OF ANION CHANNEL ACTIVITY IN CHONDROCYTES IN VITRO MODEL OF OSTEOARTHRITIS (Conference Paper)
Kumagai, K., Toyoda, F., Staunton, C., Sharif, U., Lewis, R., Maeda, T., . . . Barrett-Jolley, R. (2018). ANALYSIS OF ANION CHANNEL ACTIVITY IN CHONDROCYTES IN VITRO MODEL OF OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S104). doi:10.1016/j.joca.2018.02.226DOI: 10.1016/j.joca.2018.02.226
Staunton, C. A., Barrett-Jolley, R., Djouhri, L., & Thippeswamy, T. (2018). Inducible nitric oxide synthase inhibition by 1400W limits pain hypersensitivity in a neuropathic pain rat model. EXPERIMENTAL PHYSIOLOGY, 103(04), 535-544. doi:10.1113/EP086764DOI: 10.1113/EP086764
Do senescent cells drive the ageing phenotype of skeletal muscle in vivo? (Conference Paper)
Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Do senescent cells drive the ageing phenotype of skeletal muscle in vivo?. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
Ion Channel Activity in a 3-hydroxyacyl-coA dehydratase 1 (HACD1) Deficient Muscle Cell Line (Conference Paper)
Morgan, R. S., Walmsley, G., Dyer, S., O'Brien, F., Staunton, C., Blondelle, J., . . . Barrett-Jolley, R. (2018). Ion Channel Activity in a 3-hydroxyacyl-coA dehydratase 1 (HACD1) Deficient Muscle Cell Line. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia. (Conference Paper)
Staunton, C. A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. J. (2018). Novel intravital assessment of muscle cytosol H<sub>2</sub>0<sub>2</sub> content supports a key role for motor unit remodelling in sarcopenia.. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
Senescence in Myoblasts; Role in Age-Related Muscle Dysfunction (Conference Paper)
Shigdar, S., Staunton, C., Vasilaki, A., & McArdle, A. (2018). Senescence in Myoblasts; Role in Age-Related Muscle Dysfunction. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
2017
Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. J. (2017). Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging. FREE RADICAL BIOLOGY AND MEDICINE, 112, 84-92. doi:10.1016/j.freeradbiomed.2017.07.017DOI: 10.1016/j.freeradbiomed.2017.07.017
Kumagai, K., O'Neill, N., Zouggari, S., Staunton, C. A., Bavany, S., Hadair, O., . . . Barrett-Jolley, R. (2017). CHANGES IN ION CHANNEL EXPRESSION IN SYNOVIAL FIBROBLASTS IN AN IN VITRO MODEL OF OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 25 (pp. S380-S381). doi:10.1016/j.joca.2017.02.651DOI: 10.1016/j.joca.2017.02.651
Neuromuscular regeneration following whole muscle transplantation (Conference Paper)
Pollock, N., Davis, C. S., Hassett, C. A., Staunton, C. A., Vasilaki, A., Jackson, M. J., . . . McArdle, A. (2017). Neuromuscular regeneration following whole muscle transplantation. In FASEB JOURNAL Vol. 31. Retrieved from https://www.webofscience.com/
The role of hydrogen peroxide production in skeletal muscle dysfunction following nerve crush. (Conference Paper)
Staunton, C. A., Pollock, N., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. J. (2017). The role of hydrogen peroxide production in skeletal muscle dysfunction following nerve crush.. In FASEB JOURNAL Vol. 31. Retrieved from https://www.webofscience.com/
2016
Effect of Partial Denervation on Mitochondrial ROS Generation in Skeletal Muscle; a Role in Sarcopenia? (Conference Paper)
Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. J. (2016). Effect of Partial Denervation on Mitochondrial ROS Generation in Skeletal Muscle; a Role in Sarcopenia?. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 100 (pp. S86-S87). doi:10.1016/j.freeradbiomed.2016.10.216DOI: 10.1016/j.freeradbiomed.2016.10.216
The Role of Denervation in Cytokine-Mediated Muscle Dysfunction in Old Mice (Conference Paper)
Staunton, C. A., Pollock, N., McCormick, R., Vasilaki, A., Barrett-Jolley, R., Jackson, M., & McArdle, A. (2016). The Role of Denervation in Cytokine-Mediated Muscle Dysfunction in Old Mice. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 100 (pp. S89). doi:10.1016/j.freeradbiomed.2016.10.222DOI: 10.1016/j.freeradbiomed.2016.10.222
Kumagai, K., Toyoda, F., staunton, C., Maeda, T., Okumura, N., Matsuura, H., . . . Barrett-jolley, R. (2016). Activation of a chondrocyte volume-sensitive Cl(-) conductance prior to macroscopic cartilage lesion formation in the rabbit knee anterior cruciate ligament transection osteoarthritis model.. Osteoarthritis and Cartilage, 24(10), 1786-1794. doi:10.1016/j.joca.2016.05.019DOI: 10.1016/j.joca.2016.05.019
Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle (Conference Paper)
Jackson, M. J., Vasilaki, A., Pollock, N., Staunton, C., McDonagh, B., & McArdle, A. (2016). Age-related neuromuscular deficits in reactive oxygen species generation in exercising skeletal muscle. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 96 (pp. S13). doi:10.1016/j.freeradbiomed.2016.04.059DOI: 10.1016/j.freeradbiomed.2016.04.059
Effect of partial denervation mitochondrial ROS generation in skeletal muscle (Conference Paper)
Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. (2016). Effect of partial denervation mitochondrial ROS generation in skeletal muscle. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/
Effects of TNFα challenge on sensory neuron ion channel expression and temperature sensitivity (Conference Paper)
Staunton, C. A., Kumagai, K. A., Thippeswamy, T., Djourhi, L., & Barrett-Jolley, R. A. (2016). Effects of TNFα challenge on sensory neuron ion channel expression and temperature sensitivity. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/
The role of denervation in cytokine-mediated muscle dysfunction in muscles of old mice (Conference Paper)
Staunton, C. A., Pollock, N., Lightfoot, A., Vasilaki, A., Barrett-Jolley, R., McArdle, A., & Jackson, M. (2016). The role of denervation in cytokine-mediated muscle dysfunction in muscles of old mice. In FASEB JOURNAL Vol. 30. Retrieved from https://www.webofscience.com/
2015
Nutrigenomics, Inflammaging, and Osteoarthritis (Chapter)
Mobasheri, A., Barrett‐Jolley, R., Staunton, C. A., Ford, C., & Henrotin, Y. (2015). Nutrigenomics, Inflammaging, and Osteoarthritis. In Unknown Book (pp. 71-84). Wiley. doi:10.1002/9781118930458.ch7DOI: 10.1002/9781118930458.ch7
Wibberley, A., Staunton, C., Feetham, C., Vereninov, A. A., & Barrett-Jolley, R. (2015). An In Vitro Model of Skeletal Muscle Volume Regulation. PLoS One, 10(6). doi:10.1371/journal.pone.0127889DOI: 10.1371/journal.pone.0127889
Cytokine Expression Profiles and Electrophysiological Recordings of Dorsal Root Ganglion Cells in an <i>In Vitro</i> Model of Chronic Pain (Conference Paper)
Staunton, C., Barrett-Jolley, R., Djouhri, L., & Thippeswamy, T. (2015). Cytokine Expression Profiles and Electrophysiological Recordings of Dorsal Root Ganglion Cells in an <i>In Vitro</i> Model of Chronic Pain. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/
2014
Staunton, C. A., Mobasheri, A., & Barrett-Jolley, R. (2014). High hopes for cannabinoid agonists in the treatment of rheumatic diseases. BMC MUSCULOSKELETAL DISORDERS, 15. doi:10.1186/1471-2474-15-410DOI: 10.1186/1471-2474-15-410
2013
Staunton, C. A., Lewis, R., & Barrett-Jolley, R. (2013). Ion Channels and Osteoarthritic Pain: Potential for Novel Analgesics. CURRENT PAIN AND HEADACHE REPORTS, 17(12). doi:10.1007/s11916-013-0378-zDOI: 10.1007/s11916-013-0378-z
