Dr Anna Daroszewska FRCP(Ed) PhD

Senior Clinical Lecturer Musculoskeletal Biology I

    Publications

    2018

    Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre. (Journal article)

    Ranganath, L. R., Khedr, M., Milan, A. M., Davison, A. S., Hughes, A. T., Usher, J. L., . . . Gallagher, J. A. (2018). Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre.. Molecular genetics and metabolism. doi:10.1016/j.ymgme.2018.07.011

    DOI: 10.1016/j.ymgme.2018.07.011

    Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease. (Journal article)

    Daroszewska, A., Rose, L., Sarsam, N., Charlesworth, G., Prior, A., Rose, K., . . . van 't Hof, R. J. (2018). Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease.. Disease models & mechanisms, 11(9). doi:10.1242/dmm.035576

    DOI: 10.1242/dmm.035576

    2017

    Analysis of Nkx3.1: Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity (Journal article)

    Loveridge, C. J., van't Hof, R. J., Charlesworth, G., King, A., Tan, E. H., Rose, L., . . . Leung, H. Y. (2017). Analysis of Nkx3.1: Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-13346-8

    DOI: 10.1038/s41598-017-13346-8

    Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density (Journal article)

    Alonso, N., Estrada, K., Albagha, O. M. E., Herrera, L., Reppe, S., Olstad, O. K., . . . Ralston, S. H. (2018). Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density. ANNALS OF THE RHEUMATIC DISEASES, 77(3). doi:10.1136/annrheumdis-2017-212469

    DOI: 10.1136/annrheumdis-2017-212469

    Open source software for semi-automated histomorphometry of bone resorption and formation parameters (Journal article)

    van't Hof, R. J., Rose, L., Bassonga, E., & Daroszewska, A. (2017). Open source software for semi-automated histomorphometry of bone resorption and formation parameters. BONE, 99, 69-79. doi:10.1016/j.bone.2017.03.051

    DOI: 10.1016/j.bone.2017.03.051

    2015

    Prevention and treatment of osteoporosis in women: an update (Journal article)

    Daroszewska, A. (2015). Prevention and treatment of osteoporosis in women: an update. Obstetrics, Gynaecology & Reproductive Medicine, 25(7), 181-187. doi:10.1016/j.ogrm.2015.04.001

    DOI: 10.1016/j.ogrm.2015.04.001

    2014

    Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus (Journal article)

    Oei, L., Estrada, K., Duncan, E. L., Christiansen, C., Liu, C. -T., Langdahl, B. L., . . . Rivadeneira, F. (2014). Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus. BONE, 59, 20-27. doi:10.1016/j.bone.2013.10.015

    DOI: 10.1016/j.bone.2013.10.015

    Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus (Journal article)

    Oei, L., Estrada, K., Duncan, E. L., Christiansen, C., Liu, C. T., Langdahl, B. L., . . . Rivadeneira, F. (2014). Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone, 59, 20-27. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/24516880

    2012

    Prevention and treatment of osteoporosis in women: an update (Journal article)

    Daroszewska, A. (2012). Prevention and treatment of osteoporosis in women: an update. Obstetrics, Gynaecology and Reproductive Medicine, 22(6), 162-169.

    2011

    A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice (Journal article)

    Daroszewska, A., van't Hof, R. J., Rojas, J. A., Layfield, R., Landao-Basonga, E., Rose, L., . . . Ralston, S. H. (2011). A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice. HUMAN MOLECULAR GENETICS, 20(14), 2734-2744. doi:10.1093/hmg/ddr172

    DOI: 10.1093/hmg/ddr172

    2010

    Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone (Journal article)

    Chung, P. Y. J., Beyens, G., Riches, P. L., Van Wesenbeeck, L., de Freitas, F., Jennes, K., . . . Van Hul, W. (2010). Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone. Journal of Bone and Mineral Research, 25(12), 2592-2605. doi:10.1002/jbmr.162

    DOI: 10.1002/jbmr.162

    Unilateral glossopharyngeal and hypoglossal nerve palsies due to compression by a rheumatoid pannus (Journal article)

    Mathew, R., Mumford, C. J., & Daroszewska, A. (2010). Unilateral glossopharyngeal and hypoglossal nerve palsies due to compression by a rheumatoid pannus. Rheumatology, 49(10), 1996-1997. doi:10.1093/rheumatology/keq156

    DOI: 10.1093/rheumatology/keq156

    2009

    Chapter: Other Bone Diseases (Chapter)

    Ralston, S. H., Daroszewska, A., & Podenphant, J. (2009). Chapter: Other Bone Diseases. In J. W. Bijlsma (Ed.), EULAR Compendium on Rheumatic Diseases (pp. 546-555). London: BMJ Publishing Group and European League Against Rheumatism.

    2007

    Identification of Sex-Specific Associations Between Polymorphisms of the Osteoprotegerin Gene, TNFRSF11B, and Paget's Disease of Bone (Journal article)

    Beyens, G., Daroszewska, A., de Freitas, F., Fransen, E., Vanhoenacker, F., Verbruggen, L., . . . Van Hul, W. (2007). Identification of Sex-Specific Associations Between Polymorphisms of the Osteoprotegerin Gene, TNFRSF11B, and Paget's Disease of Bone. Journal of Bone and Mineral Research, 22(7), 1062-1071. doi:10.1359/jbmr.070333

    DOI: 10.1359/jbmr.070333

    2006

    Contribution of Genetic Factors to the Pathogenesis of Paget's Disease of Bone and Related Disorders (Journal article)

    Lucas, G. J., Daroszewska, A., & Ralston, S. H. (2006). Contribution of Genetic Factors to the Pathogenesis of Paget's Disease of Bone and Related Disorders. Journal of Bone and Mineral Research, 21(S2), P31-P37. doi:10.1359/jbmr.06s206

    DOI: 10.1359/jbmr.06s206

    Mechanisms of Disease: genetics of Paget's disease of bone and related disorders (Journal article)

    Daroszewska, A., & Ralston, S. H. (2006). Mechanisms of Disease: genetics of Paget's disease of bone and related disorders. Nature Clinical Practice Rheumatology, 2(5), 270-277. doi:10.1038/ncprheum0172

    DOI: 10.1038/ncprheum0172

    2005

    Genetics of Paget's disease of bone (Journal article)

    Daroszewska, A., & Ralston, S. (2005). Genetics of Paget's disease of bone. Clinical Science, 109(3), 257-263. doi:10.1042/CS20050053

    DOI: 10.1042/CS20050053

    Ubiquitin-Associated Domain Mutations of SQSTM1 in Paget's Disease of Bone: Evidence for a Founder Effect in Patients of British Descent (Journal article)

    Lucas, G. J., Hocking, L. J., Daroszewska, A., Cundy, T., Nicholson, G. C., Walsh, J. P., . . . Ralston, S. H. (2005). Ubiquitin-Associated Domain Mutations of SQSTM1 in Paget's Disease of Bone: Evidence for a Founder Effect in Patients of British Descent. Journal of Bone and Mineral Research, 20(2), 227-231. doi:10.1359/JBMR.041106

    DOI: 10.1359/JBMR.041106

    2004

    Bone turnover in untreated patients with polymyalgia rheumatica. (Journal article)

    Barnes, T., Daroszewska, A., Fraser, W., & Bucknall, R. (2004). Bone turnover in untreated patients with polymyalgia rheumatica.. Rheumatology, 43(4), 486-490. doi:10.1093/rheumatology/keh072

    DOI: 10.1093/rheumatology/keh072

    Novel UBA Domain Mutations of SQSTM1 in Paget's Disease of Bone: Genotype Phenotype Correlation, Functional Analysis, and Structural Consequences (Journal article)

    Hocking, L. J., Lucas, G. J., Daroszewska, A., Cundy, T., Nicholson, G. C., Donath, J., . . . Ralston, S. H. (2004). Novel UBA Domain Mutations of SQSTM1 in Paget's Disease of Bone: Genotype Phenotype Correlation, Functional Analysis, and Structural Consequences. Journal of Bone and Mineral Research, 19(7), 1122-1127. doi:10.1359/JBMR.0403015

    DOI: 10.1359/JBMR.0403015

    Susceptibility to Paget's Disease of Bone Is Influenced by a Common Polymorphic Variant of Osteoprotegerin (Journal article)

    Daroszewska, A., Hocking, L. J., McGuigan, F. E., Langdahl, B., Stone, M. D., Cundy, T., . . . Ralston, S. H. (2004). Susceptibility to Paget's Disease of Bone Is Influenced by a Common Polymorphic Variant of Osteoprotegerin. Journal of Bone and Mineral Research, 19(9), 1506-1511. doi:10.1359/JBMR.040602

    DOI: 10.1359/JBMR.040602

    2002

    Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease (Journal article)

    Hocking, L. J., Lucas, G. J., Daroszewska, A., Mangion, J., Olavesen, M., Cundy, T., . . . Ralston, S. H. (2002). Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease. Hum Mol Genet, 11(22), 2735-2739. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12374763

    1999

    Severe hypercalcaemia in B-cell lymphoma: combined effects of PTH-rP, IL-6 and TNF (Journal article)

    Daroszewska, A., Bucknall, R. C., Chu, P., & Fraser, W. D. (1999). Severe hypercalcaemia in B-cell lymphoma: combined effects of PTH-rP, IL-6 and TNF. Postgrad Med J, 75(889), 672-674. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/10621879

    1997

    The value of arthrography in steroid injection of the shoulder joint (Journal article)

    Goh, G. J., Over, K. E., Daroszewska, A., Whitehouse, G. H., & Bucknall, R. C. (1997). The value of arthrography in steroid injection of the shoulder joint. Br J Rheumatol, 36(6), 709-710. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/9236689
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