The blog of the Institute of Ageing & Chronic Disease
If you’re interested in how people and animals move, see, eat and age, and what we can do when things go wrong, then this blog is for you.
This is a behind the scenes look at the latest research and activities from the Institute of Ageing & Chronic Disease. We’d love to hear your questions and comments.
Year of Engineering: Improving Lives
Posted on: 6 April 2018 | Category: 2018 posts

I have been interested in design and in making things from an early age and was always interested in science subjects at school, studying maths, physics and chemistry at A-Level. My parents were medics, and I became interested in the role of engineering in medical innovation and how it could make a real difference to people’s lives. As an undergraduate student, I had an amazing opportunity to go into an operating theatre and watch open heart surgery. I saw the incredible amount of technology needed to take the blood into a bypass machine with all the pumps, filters, valves and sensors that were required to keep the patient alive while their heart was stopped so that the surgery could be carried out.
Antimicrobial contact lens development - an update
Posted on: 31 January 2018 | Category: 2018 posts

You might remember that last year we announced that a project led by Professor Rachel Williams successfully applied to the Medical Research Council’s Developmental Pathway Funding Scheme to fund the development of an antimicrobial contact lens. The lens, which is naturally antimicrobial, has applications for post-surgery infection prevention. The gels can also incorporate antibiotics and antifungals to treat microbial keratitis, one of the commonest conditions affecting the cornea. It is now month four of the project and staff have made real progress.
Treating AMD through cell transplantation
Posted on: 29 January 2018 | Category: 2018 posts

Age-related macular degeneration (AMD) is a debilitating condition which results in the loss of central vision. More than 600,000 people in the UK alone are affected by it, and in the developed world it is the most common cause of sight loss. Staff at Eye & Vision Science are working with colleagues at St Paul’s Eye Unit and the University’s School of Engineering to develop a new surgical treatment for AMD which could radically change the lives of people with both the wet and dry forms of the condition.
Outreach event for primary school children
Posted on: 28 November 2017 | Category: 2017 posts

“Inspiring, educational, awesome, factual, exhilarating, incredible, epic, fab….” These are some of the ways the children described their visit to the Institute, following the IACD Junior Science Lab on 28 November. The theme for the opening session was “The Giant Cardiovascular System”, with demonstrations and hands-on activities to explore the physiology of blood cells and circulation, the eye, and the brain. Twenty-nine Year Six children (aged 10-11) and four members of staff from St Thomas CE School (Lydiate) were amazed by their experience and excited about what they learned. Whilst 50% of the children reported previously having visited a university, only 32% had ever met a scientist before their visit.
Workshop on chemical cross-linking for the treatment of keratoconus
Posted on: 22 November 2017 | Category: 2017 posts

A workshop was organised by Eye & Vision Science staff with experts at the Aravind Eye Care System in Madurai, India to discuss the findings of a project that aims to develop a new chemical cross-linker to treat keratoconus. The workshop, on November 18th 2017, featured speakers including Professor Rachel Williams (front, second left), Professor Colin Willoughby and Dr Atikah Haneef (front, second right) from Eye and Vision Science and clinicians from across India. The workshop was funded by the Engineering & Physical Sciences Research Council under the Translational Alliance Program Scheme.
Ageing workshop & symposium
Posted on: 6 November 2017 | Category: 2017 posts
On the 26th and 27th October 2017, our lab (the Integrative Genomics of Ageing Group, led by Dr. João Pedro de Magalhães), organised a two day scientific symposium and workshop to bring together scientists researching the field of ageing.
Microbial keratitis in Malawi
Posted on: 30 October 2017 | Category: 2017 posts

Microbial keratitis is an infection of the cornea that may lead to ulcers, scarring and loss of sight. The risk factors and organisms that cause microbial keratitis are unknown in Malawi meaning that treatment is limited and outcomes are poor. One of the barriers to identifying the organisms responsible has been the difficulty in collecting samples from the cornea. This has depended on the use of sharp instruments and specialist equipment, which are not available in resource deprived settings as you find in Malawi. Dr Tobi Somerville, also of St Paul’s Eye Unit, recently tested a novel method for identifying the cause of the infection.
Diagnosing malaria in comatose children
Posted on: 23 October 2017 | Category: 2017 posts

Great strides have been taken in the battle against malaria – the biggest killer of African children under five years of age – but still around 450,000 children die from the disease every year. Many of those children will slip into a short coma during their illness; around 15% of them will die and a further 15% will suffer a neurological disability. It is therefore imperative that an accurate diagnosis is made as quickly as possible so that treatment can begin.
Tackling blindness in Malawi
Posted on: 16 October 2017 | Category: 2017 posts

Staff from Eye & Vision Science recently visited the Malawi-Liverpool Wellcome Trust Clinical Research Programme in Blantyre, Malawi, one of five Wellcome Major Overseas Programmes. This first post on their visit examines the dramatic rise of diabetes and diabetic retinopathy in Malawi and the programme’s efforts to tackle the problem.
Launch of the ONWARD Network
Posted on: 2 October 2017 | Category: 2017 posts

The National Institute for Health Research (the research arm of the NHS) Ophthalmology Speciality Group has given its approval to support a national strategy, in collaboration with the Royal College of Ophthalmologists, for supporting Trainee Research Networks. In the Liverpool region, Dr Neeru Vallabh (Glaucoma Research Fellow) will be leading.
Blog
Year of Engineering: Improving Lives
Posted on: 6 April 2018 | Category: 2018 posts

I have been interested in design and in making things from an early age and was always interested in science subjects at school, studying maths, physics and chemistry at A-Level. My parents were medics, and I became interested in the role of engineering in medical innovation and how it could make a real difference to people’s lives. As an undergraduate student, I had an amazing opportunity to go into an operating theatre and watch open heart surgery. I saw the incredible amount of technology needed to take the blood into a bypass machine with all the pumps, filters, valves and sensors that were required to keep the patient alive while their heart was stopped so that the surgery could be carried out.